MX2021009232A - Metodos de tratamiento del dolor con un antihiperalgesico de tiazolina. - Google Patents
Metodos de tratamiento del dolor con un antihiperalgesico de tiazolina.Info
- Publication number
- MX2021009232A MX2021009232A MX2021009232A MX2021009232A MX2021009232A MX 2021009232 A MX2021009232 A MX 2021009232A MX 2021009232 A MX2021009232 A MX 2021009232A MX 2021009232 A MX2021009232 A MX 2021009232A MX 2021009232 A MX2021009232 A MX 2021009232A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compound
- hyperalgesic
- thiazoline
- treating pain
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporcionan métodos para tratar el dolor neuropático diabético y el dolor posquirúrgico. Los métodos incluyen administrar a un individuo una cantidad terapéuticamente eficaz de un compuesto de Fórmula I (Compuesto 1). El método se puede usar para tratar la neuropatía diabética que surge de cualquier tipo de daño nervioso, y también se puede usar para tratar el dolor posquirúrgico que surge de cualquier procedimiento quirúrgico sin los efectos secundarios asociados con analgésicos ampliamente usados tales como los opioides. El Compuesto 1 se puede formular en muchas formas de dosificación adecuadas, incluidas formas de dosificación orales tales como comprimidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962800232P | 2019-02-01 | 2019-02-01 | |
PCT/US2019/067454 WO2020159643A1 (en) | 2019-02-01 | 2019-12-19 | Methods of treating pain with a thiazoline anti-hyperalgesic |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021009232A true MX2021009232A (es) | 2021-09-08 |
Family
ID=67211892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021009232A MX2021009232A (es) | 2019-02-01 | 2019-12-19 | Metodos de tratamiento del dolor con un antihiperalgesico de tiazolina. |
Country Status (14)
Country | Link |
---|---|
US (4) | US20200246316A1 (es) |
EP (1) | EP3917520A1 (es) |
JP (1) | JP2022523499A (es) |
KR (1) | KR20210124311A (es) |
CN (1) | CN113365626A (es) |
AU (1) | AU2019427298A1 (es) |
BR (1) | BR112021015115A2 (es) |
CA (1) | CA3126802A1 (es) |
EA (1) | EA202191947A1 (es) |
IL (1) | IL284943A (es) |
MX (1) | MX2021009232A (es) |
SG (1) | SG11202107875SA (es) |
WO (2) | WO2020159565A1 (es) |
ZA (1) | ZA202104960B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20220241200A1 (en) * | 2021-01-29 | 2022-08-04 | Insitu Biologics, Inc. | Compositions and methods for sustained treatment of pain |
WO2022266211A1 (en) * | 2021-06-17 | 2022-12-22 | Acadia Pharmaceuticals Inc. | Methods of treating, ameliorating, and/or preventing osteoarthritic pain |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
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US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
US5007790A (en) | 1989-04-11 | 1991-04-16 | Depomed Systems, Inc. | Sustained-release oral drug dosage form |
AU668386B2 (en) | 1992-03-25 | 1996-05-02 | Depomed Systems, Incorporated | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
US5582837A (en) | 1992-03-25 | 1996-12-10 | Depomed, Inc. | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
WO1997047285A1 (en) | 1996-06-10 | 1997-12-18 | Depomed, Inc. | Gastric-retentive oral controlled drug delivery system with enhanced retention properties |
US5972389A (en) | 1996-09-19 | 1999-10-26 | Depomed, Inc. | Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter |
PT998271E (pt) | 1997-06-06 | 2005-10-31 | Depomed Inc | Formas de dosagem oral de farmacos com retencao gastrica para a libertacao controlada de farmacos altamente soluveis |
US6635280B2 (en) | 1997-06-06 | 2003-10-21 | Depomed, Inc. | Extending the duration of drug release within the stomach during the fed mode |
US6323219B1 (en) | 1998-04-02 | 2001-11-27 | Ortho-Mcneil Pharmaceutical, Inc. | Methods for treating immunomediated inflammatory disorders |
IL149421A0 (en) | 1999-11-02 | 2002-11-10 | Depomed Inc | Pharmaceutical compositions containing fed mode inducing agents |
AU767812B2 (en) | 2000-02-04 | 2003-11-27 | Depomed, Inc. | Shell-and-core dosage form approaching zero-order drug release |
US6488962B1 (en) | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
US6451808B1 (en) | 2000-10-17 | 2002-09-17 | Depomed, Inc. | Inhibition of emetic effect of metformin with 5-HT3 receptor antagonists |
KR20040020056A (ko) | 2001-05-29 | 2004-03-06 | 디포메드 디벨롭먼트 리미티드 | 위식도 역류 질환 및 야간 위산분비의 치료 방법 |
CA2409552A1 (en) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
US6723340B2 (en) | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
EP1438027A1 (en) | 2001-10-25 | 2004-07-21 | DepoMed, Inc. | Methods of treatment using a gastric retained losartan dosage |
US20030091630A1 (en) | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
CN101272684A (zh) * | 2005-07-26 | 2008-09-24 | 多夫药品公司 | 治疗神经病及相关病症的方法及组合物 |
CN101484152A (zh) * | 2006-06-08 | 2009-07-15 | 舒沃茨药物股份公司 | 用于疼痛性医学病症的治疗组合 |
NL2003786C2 (en) * | 2009-11-11 | 2010-07-30 | Medner B V | COMPOSITION FOR TOPICAL APPLICATION, USES THEREOF, APPLICATOR DEVICE AND KIT OF PARTS. |
WO2011112602A1 (en) * | 2010-03-10 | 2011-09-15 | Galleon Pharmaceuticals, Inc. | Analgesic compounds, compositions, and uses thereof |
US10400264B2 (en) * | 2016-12-01 | 2019-09-03 | Promega Corporation | 5,5-disubstituted luciferins and their use in luciferase-based assays |
-
2019
- 2019-06-19 WO PCT/US2019/038028 patent/WO2020159565A1/en active Application Filing
- 2019-06-19 US US16/446,307 patent/US20200246316A1/en not_active Abandoned
- 2019-12-19 BR BR112021015115-0A patent/BR112021015115A2/pt not_active Application Discontinuation
- 2019-12-19 CA CA3126802A patent/CA3126802A1/en active Pending
- 2019-12-19 SG SG11202107875SA patent/SG11202107875SA/en unknown
- 2019-12-19 CN CN201980091049.3A patent/CN113365626A/zh active Pending
- 2019-12-19 WO PCT/US2019/067454 patent/WO2020159643A1/en unknown
- 2019-12-19 KR KR1020217027712A patent/KR20210124311A/ko unknown
- 2019-12-19 EP EP19839575.8A patent/EP3917520A1/en not_active Withdrawn
- 2019-12-19 EA EA202191947A patent/EA202191947A1/ru unknown
- 2019-12-19 JP JP2021544282A patent/JP2022523499A/ja active Pending
- 2019-12-19 AU AU2019427298A patent/AU2019427298A1/en active Pending
- 2019-12-19 US US16/720,819 patent/US20200246318A1/en not_active Abandoned
- 2019-12-19 MX MX2021009232A patent/MX2021009232A/es unknown
-
2020
- 2020-05-28 US US16/886,074 patent/US20200289474A1/en not_active Abandoned
-
2021
- 2021-07-14 ZA ZA2021/04960A patent/ZA202104960B/en unknown
- 2021-07-19 IL IL284943A patent/IL284943A/en unknown
- 2021-11-03 US US17/518,349 patent/US20220168279A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
SG11202107875SA (en) | 2021-08-30 |
EP3917520A1 (en) | 2021-12-08 |
US20200246318A1 (en) | 2020-08-06 |
US20200246316A1 (en) | 2020-08-06 |
WO2020159643A1 (en) | 2020-08-06 |
IL284943A (en) | 2021-09-30 |
WO2020159565A1 (en) | 2020-08-06 |
ZA202104960B (en) | 2023-12-20 |
CN113365626A (zh) | 2021-09-07 |
BR112021015115A2 (pt) | 2021-09-28 |
CA3126802A1 (en) | 2020-08-06 |
JP2022523499A (ja) | 2022-04-25 |
US20220168279A1 (en) | 2022-06-02 |
EA202191947A1 (ru) | 2021-11-03 |
US20200289474A1 (en) | 2020-09-17 |
KR20210124311A (ko) | 2021-10-14 |
AU2019427298A1 (en) | 2021-08-12 |
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