MX2016004283A - Biomarcadores para la actividad, e intesidad y arrebato de la enfermedad lupus eritematoso sistemico. - Google Patents

Biomarcadores para la actividad, e intesidad y arrebato de la enfermedad lupus eritematoso sistemico.

Info

Publication number
MX2016004283A
MX2016004283A MX2016004283A MX2016004283A MX2016004283A MX 2016004283 A MX2016004283 A MX 2016004283A MX 2016004283 A MX2016004283 A MX 2016004283A MX 2016004283 A MX2016004283 A MX 2016004283A MX 2016004283 A MX2016004283 A MX 2016004283A
Authority
MX
Mexico
Prior art keywords
biomarkers
lupus erythematosus
systemic lupus
flare
intensity
Prior art date
Application number
MX2016004283A
Other languages
English (en)
Inventor
A James Judith
E Munroe Melissa
Original Assignee
Oklahoma Med Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma Med Res Found filed Critical Oklahoma Med Res Found
Publication of MX2016004283A publication Critical patent/MX2016004283A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

La presente invención implica la identificación de biomarcadores que son proféticos de arrebatos inminentes de la enfermedad lupus eritematoso sistémico (SLE); se proveen también métodos para tratar a los pacientes identificados de esta manera.
MX2016004283A 2013-10-03 2014-10-02 Biomarcadores para la actividad, e intesidad y arrebato de la enfermedad lupus eritematoso sistemico. MX2016004283A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361886189P 2013-10-03 2013-10-03
PCT/US2014/058812 WO2015051110A1 (en) 2013-10-03 2014-10-02 Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare

Publications (1)

Publication Number Publication Date
MX2016004283A true MX2016004283A (es) 2016-10-12

Family

ID=52777119

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016004283A MX2016004283A (es) 2013-10-03 2014-10-02 Biomarcadores para la actividad, e intesidad y arrebato de la enfermedad lupus eritematoso sistemico.

Country Status (9)

Country Link
US (4) US20150098940A1 (es)
EP (1) EP3052193B1 (es)
AU (1) AU2014329535B2 (es)
BR (1) BR112016007391A2 (es)
CA (1) CA2925004C (es)
IL (1) IL244734A0 (es)
MX (1) MX2016004283A (es)
SG (1) SG11201602540XA (es)
WO (1) WO2015051110A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150098940A1 (en) * 2013-10-03 2015-04-09 Oklahoma Medical Research Foundation Biomarkers for Systemic Lupus Erythematosus Disease Activity, and Intensity and Flare
US20170315119A1 (en) * 2014-10-07 2017-11-02 University Health Network Urinary biomarkers for sle and lupus nephritis
WO2017140794A1 (en) * 2016-02-16 2017-08-24 Celltrend Gmbh Anti-cxc chemokine receptor antibodies and c-x-c chemokines for the diagnosis of autoimmune disease and graft-versus-host disease
US20190390278A1 (en) * 2017-01-26 2019-12-26 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US20180364229A1 (en) * 2017-06-16 2018-12-20 Oklahoma Medical Research Foundation Biomarkers for Assessing Risk of Transitioning to Systemic Lupus Erythematosus Classification and Disease Pathogenesis
JP6944700B2 (ja) * 2017-10-02 2021-10-06 学校法人 川崎学園 自己免疫異常の検査方法
KR102074798B1 (ko) * 2018-06-15 2020-02-07 코아스템(주) 자가면역질환 치료에 대한 유효성 예측용 바이오마커, 진단키트 및 치료용 용도
EP3867645A4 (en) * 2018-10-18 2022-07-13 Oklahoma Medical Research Foundation SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) DISEASE ACTIVITY IMMUNE INDEX BIOMARKERS THAT CHARACTERIZE DISEASE ACTIVITY
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EP4031880A4 (en) * 2019-09-20 2023-08-23 Oklahoma Medical Research Foundation SOLUBLE MEDIATORS FOR PREDICTING SYSTEMIC LUPUS ERYTHEMATOSUS ACTIVITY EVENTS
US11367521B1 (en) 2020-12-29 2022-06-21 Kpn Innovations, Llc. System and method for generating a mesodermal outline nourishment program

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Also Published As

Publication number Publication date
US20150098940A1 (en) 2015-04-09
US11585810B2 (en) 2023-02-21
US20230266315A1 (en) 2023-08-24
BR112016007391A2 (pt) 2017-08-01
CA2925004C (en) 2019-04-30
IL244734A0 (en) 2016-04-21
CA2925004A1 (en) 2015-04-09
EP3052193A1 (en) 2016-08-10
WO2015051110A1 (en) 2015-04-09
US20160349256A1 (en) 2016-12-01
AU2014329535B2 (en) 2017-09-07
SG11201602540XA (en) 2016-04-28
US10393739B2 (en) 2019-08-27
US20200049705A1 (en) 2020-02-13
EP3052193A4 (en) 2017-03-08
EP3052193B1 (en) 2018-01-31

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