MX2020005736A - Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. - Google Patents
Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida.Info
- Publication number
- MX2020005736A MX2020005736A MX2020005736A MX2020005736A MX2020005736A MX 2020005736 A MX2020005736 A MX 2020005736A MX 2020005736 A MX2020005736 A MX 2020005736A MX 2020005736 A MX2020005736 A MX 2020005736A MX 2020005736 A MX2020005736 A MX 2020005736A
- Authority
- MX
- Mexico
- Prior art keywords
- glutarimide derivatives
- general formula
- methods
- producing
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
La presente invencion se relaciona con derivados de glutarimida biológicamente activos novedosos de formula general (I) o sales farmaceuticamente aceptables de los mismos, el uso de los mismos como agentes para tratar enfermedades del tracto respiratorio superior, composiciones farmaceuticas que contienen derivados de glutarimida de formula general (I) y metodos para producir derivados de glutarimida de formula general (I) calentando una monoamida de ácido dicarboxilico de formula general (II) con un agente deshidratante.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2013116826A RU2562773C3 (ru) | 2013-04-12 | Производные глутаримидов, их применение, фармацевтическая композиция на их основе, способы их получения | |
PCT/RU2014/000264 WO2014168522A1 (ru) | 2013-04-12 | 2014-04-10 | Производные глутаримидов, их применение, фармацевтическая композиция на их основе, способы их получения |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020005736A true MX2020005736A (es) | 2021-06-14 |
Family
ID=51689819
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015014336A MX2015014336A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. |
MX2020005738A MX2020005738A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. |
MX2020005736A MX2020005736A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. |
MX2020005735A MX2020005735A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composición farmacéutica basada en los mismos y métodos para producir derivados de glutarimida. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015014336A MX2015014336A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. |
MX2020005738A MX2020005738A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composicion farmaceutica basada en los mismos y metodos para producir derivados de glutarimida. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020005735A MX2020005735A (es) | 2013-04-12 | 2014-04-10 | Derivados de glutarimida, uso de los mismos, composición farmacéutica basada en los mismos y métodos para producir derivados de glutarimida. |
Country Status (15)
Country | Link |
---|---|
US (8) | US9815814B2 (es) |
EP (3) | EP3722290B1 (es) |
JP (4) | JP6529958B2 (es) |
KR (3) | KR102255929B1 (es) |
CN (4) | CN110229140B (es) |
AU (5) | AU2014251442A1 (es) |
BR (3) | BR112015025804B1 (es) |
CA (1) | CA2909057C (es) |
EA (4) | EA032938B1 (es) |
IL (4) | IL266301B2 (es) |
MX (4) | MX2015014336A (es) |
SG (4) | SG11201508394UA (es) |
UA (1) | UA121299C2 (es) |
WO (1) | WO2014168522A1 (es) |
ZA (3) | ZA201508278B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2014251442A1 (en) * | 2013-04-12 | 2015-12-03 | Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises" | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives |
RU2552929C1 (ru) * | 2013-11-14 | 2015-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний |
RU2628800C2 (ru) * | 2014-03-12 | 2017-08-22 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
CN106539792B (zh) * | 2016-11-07 | 2017-08-25 | 王晓旭 | 一种治疗高血脂症的药物 |
GEP20227354B (en) * | 2017-09-07 | 2022-02-25 | Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises | Use of a glutarimide derivative to treat diseases related to the aberrant activity of cytokines |
JP2022506892A (ja) * | 2018-11-01 | 2022-01-17 | アハンムネ バイオサイエンシーズ プライベート リミテッド | 新規なイミダゾール化合物、その合成法及びその使用 |
RU2712281C1 (ru) | 2018-11-23 | 2020-01-28 | Общество С Ограниченной Ответственностью "Хемиммьюн Терапьютикс" | Применение производного глутаримида для преодоления резистентности к стероидам и терапии заболеваний, ассоциированных с аберрантным сигналингом интерферона гамма |
MA58653B1 (fr) * | 2020-06-26 | 2024-02-29 | Valenta Intellekt Ltd | Utilisation d'un dérivé de glutarimide pour traiter des maladies liées à l'activité aberrante d'interleukine-6 |
WO2023121519A1 (ru) * | 2021-12-23 | 2023-06-29 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Применение 1-[2-(1-метилимидазол-4-ил)-этил]пергидроазин-2,6-диона для лечения covid-19 |
WO2023177329A1 (ru) * | 2022-03-18 | 2023-09-21 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Применение 1-(2-(1н-имидазол-4-ил)этил)пиперидин-2,6-диона для лечения кашля, вызванного вирусными инфекциями |
WO2023191666A1 (ru) * | 2022-03-29 | 2023-10-05 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Кристаллическая форма 1-(2-(1н-имидазол-4-ил)этил)пиперидин-2,6-диона и ее применение |
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AU2014251442A1 (en) | 2013-04-12 | 2015-12-03 | Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises" | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives |
RU2665688C2 (ru) * | 2013-04-12 | 2018-09-04 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения |
RU2552929C1 (ru) * | 2013-11-14 | 2015-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний |
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2014
- 2014-04-10 AU AU2014251442A patent/AU2014251442A1/en not_active Abandoned
- 2014-04-10 CN CN201910437241.5A patent/CN110229140B/zh active Active
- 2014-04-10 CA CA2909057A patent/CA2909057C/en active Active
- 2014-04-10 BR BR112015025804-2A patent/BR112015025804B1/pt not_active IP Right Cessation
- 2014-04-10 CN CN201910437243.4A patent/CN110172055B/zh active Active
- 2014-04-10 KR KR1020157032457A patent/KR102255929B1/ko active IP Right Grant
- 2014-04-10 SG SG11201508394UA patent/SG11201508394UA/en unknown
- 2014-04-10 EA EA201792597A patent/EA032938B1/ru not_active IP Right Cessation
- 2014-04-10 SG SG10201802647QA patent/SG10201802647QA/en unknown
- 2014-04-10 EP EP20178489.9A patent/EP3722290B1/en active Active
- 2014-04-10 BR BR122020010210-1A patent/BR122020010210B1/pt not_active IP Right Cessation
- 2014-04-10 UA UAA201511008A patent/UA121299C2/uk unknown
- 2014-04-10 JP JP2016507512A patent/JP6529958B2/ja active Active
- 2014-04-10 CN CN201910437242.XA patent/CN110128406B/zh active Active
- 2014-04-10 MX MX2015014336A patent/MX2015014336A/es unknown
- 2014-04-10 KR KR1020207016268A patent/KR102254315B1/ko active IP Right Grant
- 2014-04-10 BR BR122020010204-7A patent/BR122020010204B1/pt active IP Right Grant
- 2014-04-10 EA EA201591957A patent/EA031392B1/ru unknown
- 2014-04-10 EA EA201792072A patent/EA032951B1/ru unknown
- 2014-04-10 CN CN201480032755.8A patent/CN106061962B/zh not_active Expired - Fee Related
- 2014-04-10 WO PCT/RU2014/000264 patent/WO2014168522A1/ru active Application Filing
- 2014-04-10 KR KR1020207016274A patent/KR102296182B1/ko active IP Right Grant
- 2014-04-10 IL IL266301A patent/IL266301B2/en unknown
- 2014-04-10 MX MX2020005738A patent/MX2020005738A/es unknown
- 2014-04-10 EA EA201792071A patent/EA033054B1/ru unknown
- 2014-04-10 SG SG10201802650WA patent/SG10201802650WA/en unknown
- 2014-04-10 MX MX2020005736A patent/MX2020005736A/es unknown
- 2014-04-10 EP EP14782170.6A patent/EP2985282A4/en not_active Withdrawn
- 2014-04-10 MX MX2020005735A patent/MX2020005735A/es unknown
- 2014-04-10 US US14/783,911 patent/US9815814B2/en active Active
- 2014-04-10 SG SG10201802648SA patent/SG10201802648SA/en unknown
- 2014-04-10 EP EP20178488.1A patent/EP3725785B1/en active Active
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2015
- 2015-10-11 IL IL241998A patent/IL241998B/en active IP Right Grant
- 2015-11-10 ZA ZA2015/08278A patent/ZA201508278B/en unknown
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2016
- 2016-05-10 ZA ZA2016/03108A patent/ZA201603108B/en unknown
- 2016-05-10 ZA ZA2016/03109A patent/ZA201603109B/en unknown
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2017
- 2017-09-28 US US15/718,252 patent/US10155745B2/en active Active
- 2017-09-28 US US15/718,295 patent/US10155746B2/en active Active
- 2017-09-28 US US15/718,226 patent/US10155744B2/en active Active
- 2017-09-28 US US15/718,207 patent/US10155743B2/en active Active
- 2017-09-28 US US15/718,316 patent/US10155747B2/en active Active
- 2017-09-28 US US15/718,274 patent/US10196377B2/en active Active
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2018
- 2018-09-27 AU AU2018236805A patent/AU2018236805C1/en not_active Ceased
- 2018-11-07 JP JP2018209573A patent/JP6627039B2/ja active Active
- 2018-11-07 JP JP2018209574A patent/JP6620324B2/ja active Active
- 2018-11-07 JP JP2018209575A patent/JP6843103B2/ja active Active
- 2018-11-15 US US16/192,065 patent/US10377739B2/en active Active
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2019
- 2019-04-29 IL IL266302A patent/IL266302B/en unknown
- 2019-04-29 IL IL266300A patent/IL266300B/en unknown
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2020
- 2020-06-02 AU AU2020203630A patent/AU2020203630B2/en active Active
- 2020-06-02 AU AU2020203632A patent/AU2020203632B2/en active Active
- 2020-06-15 AU AU2020203968A patent/AU2020203968B2/en not_active Ceased
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