SG10201802650WA - Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives - Google Patents

Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

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Publication number
SG10201802650WA
SG10201802650WA SG10201802650WA SG10201802650WA SG10201802650WA SG 10201802650W A SG10201802650W A SG 10201802650WA SG 10201802650W A SG10201802650W A SG 10201802650WA SG 10201802650W A SG10201802650W A SG 10201802650WA SG 10201802650W A SG10201802650W A SG 10201802650WA
Authority
SG
Singapore
Prior art keywords
glutarimide derivatives
methods
pharmaceutical composition
composition based
producing
Prior art date
Application number
SG10201802650WA
Inventor
Vladimir Evgenievich Nebolsin
Tatyana Alexandrovna Kromova
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2013116826A external-priority patent/RU2562773C3/en
Application filed by Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises filed Critical Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
Publication of SG10201802650WA publication Critical patent/SG10201802650WA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
SG10201802650WA 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives SG10201802650WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2013116826A RU2562773C3 (en) 2013-04-12 GLUTARIMIDE DERIVATIVES, THEIR APPLICATION, PHARMACEUTICAL COMPOSITION BASED ON THEM, METHODS OF THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
SG10201802650WA true SG10201802650WA (en) 2018-05-30

Family

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SG10201802650WA SG10201802650WA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG10201802648SA SG10201802648SA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG10201802647QA SG10201802647QA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG11201508394UA SG11201508394UA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

Family Applications After (3)

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SG10201802648SA SG10201802648SA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG10201802647QA SG10201802647QA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG11201508394UA SG11201508394UA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

Country Status (15)

Country Link
US (8) US9815814B2 (en)
EP (3) EP2985282A4 (en)
JP (4) JP6529958B2 (en)
KR (3) KR102254315B1 (en)
CN (4) CN106061962B (en)
AU (5) AU2014251442A1 (en)
BR (3) BR122020010210B1 (en)
CA (1) CA2909057C (en)
EA (4) EA032951B1 (en)
IL (4) IL266301B2 (en)
MX (4) MX2020005736A (en)
SG (4) SG10201802650WA (en)
UA (1) UA121299C2 (en)
WO (1) WO2014168522A1 (en)
ZA (3) ZA201508278B (en)

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UA121299C2 (en) * 2013-04-12 2020-05-12 Общєство С Огранічєнной Отвєтствєнностью "Фармінтерпрайсез" Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
RU2552929C1 (en) * 2013-11-14 2015-06-10 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Pharmaceutical composition, containing derivatives of glutarimides, and their application for treatment of eosinophilic diseases
RU2628800C2 (en) * 2014-03-12 2017-08-22 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Amide compounds, methods for production, application as means for treatment and prevention of diseases caused by rna-containing viruses
CN106539792B (en) * 2016-11-07 2017-08-25 王晓旭 A kind of medicine for treating hyperlipemia
MD4788C1 (en) * 2017-09-07 2022-09-30 Ооо "Валента-Интеллект" Use of a glutarimide derivative to treat diseases related to the aberrant activity of cytokines
JP2022506892A (en) * 2018-11-01 2022-01-17 アハンムネ バイオサイエンシーズ プライベート リミテッド New imidazole compound, its synthesis method and its use
RU2712281C1 (en) * 2018-11-23 2020-01-28 Общество С Ограниченной Ответственностью "Хемиммьюн Терапьютикс" Use of a derivative glutarimide to overcome resistance to steroids and therapy of diseases associated with aberrant signaling of interferon gamma
CN115803026A (en) * 2020-06-26 2023-03-14 瓦伦塔有限责任公司 Use of glutarimide derivatives for the treatment of diseases associated with abnormal interleukin-6 activity
WO2023121519A1 (en) * 2021-12-23 2023-06-29 Общество С Ограниченной Ответственностью "Валента-Интеллект" Use of 1-[2-(1-methylimidazole-4-yl)-ethyl]perhydroazine-2,6-dione for treating covid-19
WO2023177329A1 (en) * 2022-03-18 2023-09-21 Общество С Ограниченной Ответственностью "Валента-Интеллект" Use of 1-(2-(1н-imidazole-4-yl)ethyl)piperidine-2,6-dione to treat cough caused by viral infections
WO2023191666A1 (en) * 2022-03-29 2023-10-05 Общество С Ограниченной Ответственностью "Валента-Интеллект" Crystalline form of 1-(2-(1н-imidazole-4-yl)ethyl)piperidine-2,6-dione and use thereof

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UA121299C2 (en) * 2013-04-12 2020-05-12 Общєство С Огранічєнной Отвєтствєнностью "Фармінтерпрайсез" Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
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KR20160021092A (en) 2016-02-24
AU2020203632B2 (en) 2021-04-22
JP2019034964A (en) 2019-03-07
CA2909057C (en) 2022-03-22
KR102255929B1 (en) 2021-05-26
EA032938B1 (en) 2019-08-30
BR112015025804B1 (en) 2022-01-04
RU2562773C2 (en) 2015-09-10
IL266301B2 (en) 2023-03-01
EA201792597A3 (en) 2018-09-28
AU2020203632A1 (en) 2020-06-25
ZA201508278B (en) 2017-11-29
CA2909057A1 (en) 2014-10-16
AU2018236805B2 (en) 2020-04-09
EP3725785B1 (en) 2024-04-10
CN110229140A (en) 2019-09-13
KR20200069381A (en) 2020-06-16
RU2013116826A (en) 2014-10-20
US10155743B2 (en) 2018-12-18
MX2020005736A (en) 2021-06-14
JP6529958B2 (en) 2019-06-12
IL241998B (en) 2019-06-30
US10196377B2 (en) 2019-02-05
US20180016256A1 (en) 2018-01-18
US20190084961A1 (en) 2019-03-21
WO2014168522A4 (en) 2015-01-22
MX2020005738A (en) 2021-08-13
JP2019034966A (en) 2019-03-07
EA201792072A2 (en) 2018-04-30
AU2020203630B2 (en) 2021-04-22
EP2985282A1 (en) 2016-02-17
US10155746B2 (en) 2018-12-18
KR102296182B1 (en) 2021-09-02
EA032951B1 (en) 2019-08-30
EA031392B1 (en) 2018-12-28
IL266302B (en) 2021-09-30
MX2015014336A (en) 2016-06-07
EA033054B1 (en) 2019-08-30
EA201792597A2 (en) 2018-04-30
EA201591957A1 (en) 2016-02-29
AU2014251442A1 (en) 2015-12-03
EP3722290B1 (en) 2023-06-21
BR122020010204B1 (en) 2022-03-03
CN106061962A (en) 2016-10-26
US20180022728A1 (en) 2018-01-25
CN106061962B (en) 2019-09-06
SG11201508394UA (en) 2015-11-27
CN110172055A (en) 2019-08-27
CN110229140B (en) 2022-06-10
US10377739B2 (en) 2019-08-13
US20180016255A1 (en) 2018-01-18
AU2018236805A1 (en) 2018-10-18
IL266302A (en) 2019-06-30
IL266301B (en) 2022-11-01
US10155744B2 (en) 2018-12-18
AU2018236805C1 (en) 2020-11-05
JP6843103B2 (en) 2021-03-17
CN110128406B (en) 2021-08-27
BR122020010210B1 (en) 2022-09-20
CN110128406A (en) 2019-08-16
US10155745B2 (en) 2018-12-18
ZA201603109B (en) 2017-08-30
AU2020203630A1 (en) 2020-06-25
US9815814B2 (en) 2017-11-14
EA201792072A3 (en) 2018-09-28
JP2016516766A (en) 2016-06-09
EP3725785A1 (en) 2020-10-21
EA201792071A2 (en) 2018-04-30
BR112015025804A2 (en) 2017-07-25
EA201792071A3 (en) 2018-09-28
IL266300B (en) 2021-10-31
SG10201802647QA (en) 2018-05-30
ZA201603108B (en) 2017-08-30
AU2020203968B2 (en) 2021-04-22
IL266301A (en) 2019-06-30
US10155747B2 (en) 2018-12-18
KR102254315B1 (en) 2021-05-25
JP6627039B2 (en) 2020-01-08
US20160046598A1 (en) 2016-02-18
WO2014168522A9 (en) 2014-12-04
KR20200069380A (en) 2020-06-16
US20180016254A1 (en) 2018-01-18
MX2020005735A (en) 2021-06-21
US20180016253A1 (en) 2018-01-18
CN110172055B (en) 2021-10-29
EP3722290A1 (en) 2020-10-14
EP2985282A4 (en) 2017-02-22
SG10201802648SA (en) 2018-05-30
UA121299C2 (en) 2020-05-12
WO2014168522A1 (en) 2014-10-16
US20180016257A1 (en) 2018-01-18
JP6620324B2 (en) 2019-12-18
JP2019034965A (en) 2019-03-07
IL266300A (en) 2019-06-30
AU2020203968A1 (en) 2020-07-02

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