MX2019012849A - Metodos de tratamiento con polipeptidos del dominio extracelular del cd80. - Google Patents
Metodos de tratamiento con polipeptidos del dominio extracelular del cd80.Info
- Publication number
- MX2019012849A MX2019012849A MX2019012849A MX2019012849A MX2019012849A MX 2019012849 A MX2019012849 A MX 2019012849A MX 2019012849 A MX2019012849 A MX 2019012849A MX 2019012849 A MX2019012849 A MX 2019012849A MX 2019012849 A MX2019012849 A MX 2019012849A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- methods
- extracellular domain
- domain polypeptides
- polypeptides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940022399 cancer vaccine Drugs 0.000 abstract 1
- 238000009566 cancer vaccine Methods 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 210000003071 memory t lymphocyte Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G01N15/01—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Abstract
La presente solicitud hace referencia al uso de polipéptidos del dominio extracelular (ECD) del CD80 (B7- 1) y moléculas de fusión de CD80-ECD y su uso en métodos para aumentar la cantidad de linfocitos T de memoria central o para el tratamiento del cáncer o para el uso en composiciones de vacunas contra el cáncer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762491479P | 2017-04-28 | 2017-04-28 | |
PCT/US2018/029897 WO2018201014A1 (en) | 2017-04-28 | 2018-04-27 | Methods of treatment with cd80 extracellular domain polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019012849A true MX2019012849A (es) | 2019-11-28 |
Family
ID=62196719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012849A MX2019012849A (es) | 2017-04-28 | 2018-04-27 | Metodos de tratamiento con polipeptidos del dominio extracelular del cd80. |
Country Status (11)
Country | Link |
---|---|
US (1) | US11789010B2 (es) |
EP (1) | EP3628070B1 (es) |
JP (2) | JP2020517913A (es) |
KR (1) | KR20190139216A (es) |
CN (1) | CN110546509A (es) |
AU (1) | AU2018258661A1 (es) |
CA (1) | CA3057866A1 (es) |
EA (1) | EA201992586A1 (es) |
ES (1) | ES2899616T3 (es) |
MX (1) | MX2019012849A (es) |
WO (1) | WO2018201014A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
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PE20181300A1 (es) | 2015-11-02 | 2018-08-09 | Five Prime Therapeutics Inc | Polipeptidos del dominio extracelular de cd80 y su uso en el tratamiento del cancer |
JP2020517913A (ja) | 2017-04-28 | 2020-06-18 | ファイブ プライム セラピューティクス, インコーポレイテッド | Cd80細胞外ドメインポリペプチドによる治療方法 |
CN111148996A (zh) * | 2017-07-28 | 2020-05-12 | 百时美施贵宝公司 | 用于检查点抑制剂的预测性外周血生物标志物 |
JP2021535083A (ja) * | 2018-08-29 | 2021-12-16 | ファイブ プライム セラピューティクス, インコーポレイテッド | Cd80細胞外ドメインfc融合タンパク質投与レジメン |
US20220348657A1 (en) * | 2019-04-18 | 2022-11-03 | Five Prime Therapeutics, Inc. | Bioassay for t-cell co-stimulatory proteins containing fc domains |
EP4054721A1 (en) * | 2019-11-04 | 2022-09-14 | Five Prime Therapeutics, Inc. | Cd80 extracellular domain fc fusion protein dosing regimens |
TWI820361B (zh) * | 2019-11-27 | 2023-11-01 | 南韓商Gi醫諾微新股份有限公司 | 包含含有il-2蛋白與cd80蛋白之融合蛋白及免疫檢查點抑制劑的用於治療癌症的藥學組成物 |
EP4110802A1 (en) * | 2020-02-26 | 2023-01-04 | Five Prime Therapeutics, Inc. | Cd80 extracellular domain fc fusion protein therapy |
WO2021238904A1 (zh) * | 2020-05-25 | 2021-12-02 | 北京比洋生物技术有限公司 | Fc-CD80融合蛋白和其缀合物以及它们的用途 |
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-
2018
- 2018-04-27 JP JP2019554739A patent/JP2020517913A/ja active Pending
- 2018-04-27 US US16/608,911 patent/US11789010B2/en active Active
- 2018-04-27 WO PCT/US2018/029897 patent/WO2018201014A1/en unknown
- 2018-04-27 KR KR1020197029416A patent/KR20190139216A/ko not_active Application Discontinuation
- 2018-04-27 CN CN201880024161.0A patent/CN110546509A/zh active Pending
- 2018-04-27 EA EA201992586A patent/EA201992586A1/ru unknown
- 2018-04-27 CA CA3057866A patent/CA3057866A1/en active Pending
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2021
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EP3628070A1 (en) | 2020-04-01 |
CA3057866A1 (en) | 2018-11-01 |
EA201992586A1 (ru) | 2020-03-03 |
US11789010B2 (en) | 2023-10-17 |
WO2018201014A1 (en) | 2018-11-01 |
EP3628070B1 (en) | 2021-09-08 |
JP2020517913A (ja) | 2020-06-18 |
KR20190139216A (ko) | 2019-12-17 |
JP2021095417A (ja) | 2021-06-24 |
US20200182858A1 (en) | 2020-06-11 |
ES2899616T3 (es) | 2022-03-14 |
CN110546509A (zh) | 2019-12-06 |
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