MX2017016324A - Tratamientos de combinacion de antagonista de ligando 1 de muerte programada (pd-l1). - Google Patents
Tratamientos de combinacion de antagonista de ligando 1 de muerte programada (pd-l1).Info
- Publication number
- MX2017016324A MX2017016324A MX2017016324A MX2017016324A MX2017016324A MX 2017016324 A MX2017016324 A MX 2017016324A MX 2017016324 A MX2017016324 A MX 2017016324A MX 2017016324 A MX2017016324 A MX 2017016324A MX 2017016324 A MX2017016324 A MX 2017016324A
- Authority
- MX
- Mexico
- Prior art keywords
- combination treatments
- antagonist combination
- combination therapies
- antagonist
- receptor
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
La presente descripción describe terapias de combinación que comprenden un antagonista de un receptor de Ligando 1 de Muerte Programada (PD-L1) y otro agente terapéutico, y el uso de las terapias de combinación para el tratamiento de cáncer.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562180543P | 2015-06-16 | 2015-06-16 | |
US201562219995P | 2015-09-17 | 2015-09-17 | |
US201662286501P | 2016-01-25 | 2016-01-25 | |
US201662337489P | 2016-05-17 | 2016-05-17 | |
PCT/US2016/037498 WO2016205277A1 (en) | 2015-06-16 | 2016-06-15 | Pd-l1 antagonist combination treatments |
Publications (1)
Publication Number | Publication Date |
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MX2017016324A true MX2017016324A (es) | 2018-03-02 |
Family
ID=56236125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017016324A MX2017016324A (es) | 2015-06-16 | 2016-06-15 | Tratamientos de combinacion de antagonista de ligando 1 de muerte programada (pd-l1). |
Country Status (16)
Country | Link |
---|---|
US (2) | US10869924B2 (es) |
EP (1) | EP3310810A1 (es) |
JP (2) | JP6876629B2 (es) |
KR (1) | KR20180018762A (es) |
CN (1) | CN107750166B (es) |
AU (1) | AU2016280003B2 (es) |
CA (1) | CA2989586A1 (es) |
HK (1) | HK1248530A1 (es) |
IL (1) | IL256245B (es) |
MX (1) | MX2017016324A (es) |
MY (1) | MY193229A (es) |
PH (1) | PH12017501857A1 (es) |
RU (1) | RU2766890C2 (es) |
TW (1) | TWI772261B (es) |
UA (1) | UA126892C2 (es) |
WO (1) | WO2016205277A1 (es) |
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KR20170132171A (ko) | 2015-02-26 | 2017-12-01 | 메르크 파텐트 게엠베하 | 암 치료를 위한 pd1 / pdl1 저해제 |
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2016
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- 2016-06-15 EP EP16732440.9A patent/EP3310810A1/en active Pending
- 2016-06-15 WO PCT/US2016/037498 patent/WO2016205277A1/en active Application Filing
- 2016-06-15 MY MYPI2017704745A patent/MY193229A/en unknown
- 2016-06-15 RU RU2018101314A patent/RU2766890C2/ru active
- 2016-06-15 US US15/736,615 patent/US10869924B2/en active Active
- 2016-06-15 AU AU2016280003A patent/AU2016280003B2/en active Active
- 2016-06-15 JP JP2017565142A patent/JP6876629B2/ja active Active
- 2016-06-15 MX MX2017016324A patent/MX2017016324A/es unknown
- 2016-06-15 UA UAA201800418A patent/UA126892C2/uk unknown
- 2016-06-15 IL IL256245A patent/IL256245B/en unknown
- 2016-06-15 CA CA2989586A patent/CA2989586A1/en active Pending
- 2016-06-15 CN CN201680035168.3A patent/CN107750166B/zh active Active
- 2016-06-16 TW TW105118967A patent/TWI772261B/zh active
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2017
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2020
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US10869924B2 (en) | 2020-12-22 |
IL256245B (en) | 2022-09-01 |
JP6876629B2 (ja) | 2021-05-26 |
AU2016280003A1 (en) | 2018-02-01 |
HK1248530A1 (zh) | 2018-10-19 |
CN107750166B (zh) | 2022-02-11 |
JP2021113220A (ja) | 2021-08-05 |
CA2989586A1 (en) | 2016-12-22 |
RU2018101314A3 (es) | 2020-01-29 |
TWI772261B (zh) | 2022-08-01 |
WO2016205277A1 (en) | 2016-12-22 |
RU2018101314A (ru) | 2019-07-16 |
MY193229A (en) | 2022-09-26 |
NZ737018A (en) | 2021-11-26 |
EP3310810A1 (en) | 2018-04-25 |
PH12017501857A1 (en) | 2018-02-26 |
TW201709933A (zh) | 2017-03-16 |
UA126892C2 (uk) | 2023-02-22 |
RU2766890C2 (ru) | 2022-03-16 |
JP2018522850A (ja) | 2018-08-16 |
AU2016280003B2 (en) | 2021-09-16 |
KR20180018762A (ko) | 2018-02-21 |
IL256245A (en) | 2018-02-28 |
CN107750166A (zh) | 2018-03-02 |
US20180169232A1 (en) | 2018-06-21 |
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