MX2017003794A - Formulaciones estables de lipidos y liposomas. - Google Patents

Formulaciones estables de lipidos y liposomas.

Info

Publication number
MX2017003794A
MX2017003794A MX2017003794A MX2017003794A MX2017003794A MX 2017003794 A MX2017003794 A MX 2017003794A MX 2017003794 A MX2017003794 A MX 2017003794A MX 2017003794 A MX2017003794 A MX 2017003794A MX 2017003794 A MX2017003794 A MX 2017003794A
Authority
MX
Mexico
Prior art keywords
methods
liposomes
lipids
stable formulations
lipid
Prior art date
Application number
MX2017003794A
Other languages
English (en)
Inventor
Hernan Esparza Borquez Isaac
Haas Heinrich
Original Assignee
Biontech Rna Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biontech Rna Pharmaceuticals Gmbh filed Critical Biontech Rna Pharmaceuticals Gmbh
Publication of MX2017003794A publication Critical patent/MX2017003794A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proporcionan sistemas y métodos para determinar patógenos y resistencia antimicrobiana de patógenos en una muestra.
MX2017003794A 2014-09-25 2015-09-17 Formulaciones estables de lipidos y liposomas. MX2017003794A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2014/070503 WO2016045732A1 (en) 2014-09-25 2014-09-25 Stable formulations of lipids and liposomes
PCT/EP2015/071344 WO2016046060A1 (en) 2014-09-25 2015-09-17 Stable formulations of lipids and liposomes

Publications (1)

Publication Number Publication Date
MX2017003794A true MX2017003794A (es) 2017-07-07

Family

ID=51626523

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017003794A MX2017003794A (es) 2014-09-25 2015-09-17 Formulaciones estables de lipidos y liposomas.

Country Status (17)

Country Link
US (2) US11173120B2 (es)
EP (1) EP3197433A1 (es)
JP (1) JP6703982B2 (es)
KR (1) KR102264820B1 (es)
CN (1) CN107072945B (es)
AU (1) AU2015320980B2 (es)
BR (1) BR112017005821B1 (es)
CA (1) CA2960934C (es)
IL (2) IL250991B (es)
MA (1) MA40627A (es)
MX (1) MX2017003794A (es)
MY (1) MY184381A (es)
NZ (1) NZ730368A (es)
RU (1) RU2738060C2 (es)
SG (1) SG11201702182YA (es)
WO (2) WO2016045732A1 (es)
ZA (1) ZA201701670B (es)

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TW202206096A (zh) 2020-04-22 2022-02-16 德商拜恩迪克Ｒｎａ製藥有限公司 冠狀病毒疫苗
EP4213882A1 (en) 2020-09-15 2023-07-26 Verve Therapeutics, Inc. Lipid formulations for gene editing
WO2022235847A1 (en) 2021-05-04 2022-11-10 BioNTech SE Technologies for early detection of variants of interest
EP4376875A1 (en) 2021-07-29 2024-06-05 BioNTech SE Compositions and methods for treatment of melanoma
CN114306244B (zh) * 2022-01-14 2023-04-07 苏州尔生生物医药有限公司 一种微米级脂质复合物及其制备和应用
US11878055B1 (en) 2022-06-26 2024-01-23 BioNTech SE Coronavirus vaccine

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IL291055A (en) 2022-05-01
AU2015320980B2 (en) 2021-02-18
WO2016045732A1 (en) 2016-03-31
BR112017005821A2 (pt) 2017-12-12
RU2017113970A (ru) 2018-10-25
CA2960934A1 (en) 2016-03-31
IL250991B (en) 2022-04-01
IL250991A0 (en) 2017-04-30
US20170273907A1 (en) 2017-09-28
JP2017532322A (ja) 2017-11-02
CN107072945A (zh) 2017-08-18
CN107072945B (zh) 2021-04-06
MY184381A (en) 2021-04-01
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WO2016046060A1 (en) 2016-03-31
RU2017113970A3 (es) 2019-04-15
KR20170063780A (ko) 2017-06-08
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US11173120B2 (en) 2021-11-16
KR102264820B1 (ko) 2021-06-14
RU2738060C2 (ru) 2020-12-07
NZ730368A (en) 2024-02-23
BR112017005821B1 (pt) 2022-06-14
AU2015320980A1 (en) 2017-04-06
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JP6703982B2 (ja) 2020-06-03

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