MX2016007885A - Metodos de tratamiento de cancer usando antagonistas de union del eje de pd-1 y un anticuerpo anti-cd20. - Google Patents
Metodos de tratamiento de cancer usando antagonistas de union del eje de pd-1 y un anticuerpo anti-cd20.Info
- Publication number
- MX2016007885A MX2016007885A MX2016007885A MX2016007885A MX2016007885A MX 2016007885 A MX2016007885 A MX 2016007885A MX 2016007885 A MX2016007885 A MX 2016007885A MX 2016007885 A MX2016007885 A MX 2016007885A MX 2016007885 A MX2016007885 A MX 2016007885A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- antibody
- axis binding
- treating cancer
- binding antagonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
La presente invención describe el tratamiento de combinación que comprende un antagonista de unión del eje de PD-1 y un anticuerpo anti-CD20 y métodos para el uso de los mismos, incluyendo métodos de tratamiento de condiciones donde es deseada la inmunogenicidad mejorada, como el incremento de la inmunogenicidad del tumor para el tratamiento del cáncer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361917264P | 2013-12-17 | 2013-12-17 | |
US201462034766P | 2014-08-07 | 2014-08-07 | |
PCT/US2014/070983 WO2015095410A1 (en) | 2013-12-17 | 2014-12-17 | Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016007885A true MX2016007885A (es) | 2017-01-11 |
Family
ID=52396807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016007885A MX2016007885A (es) | 2013-12-17 | 2014-12-17 | Metodos de tratamiento de cancer usando antagonistas de union del eje de pd-1 y un anticuerpo anti-cd20. |
Country Status (13)
Country | Link |
---|---|
US (2) | US20150210772A1 (es) |
EP (1) | EP3083690A1 (es) |
JP (1) | JP2017501157A (es) |
KR (1) | KR20160089532A (es) |
CN (1) | CN105899535A (es) |
AU (1) | AU2014364593A1 (es) |
BR (1) | BR112016013741A2 (es) |
CA (1) | CA2933881A1 (es) |
IL (1) | IL246183A0 (es) |
MX (1) | MX2016007885A (es) |
RU (1) | RU2016128726A (es) |
SG (1) | SG11201604875PA (es) |
WO (1) | WO2015095410A1 (es) |
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-
2014
- 2014-12-17 BR BR112016013741A patent/BR112016013741A2/pt not_active Application Discontinuation
- 2014-12-17 SG SG11201604875PA patent/SG11201604875PA/en unknown
- 2014-12-17 MX MX2016007885A patent/MX2016007885A/es unknown
- 2014-12-17 JP JP2016539902A patent/JP2017501157A/ja active Pending
- 2014-12-17 WO PCT/US2014/070983 patent/WO2015095410A1/en active Application Filing
- 2014-12-17 EP EP14830759.8A patent/EP3083690A1/en not_active Withdrawn
- 2014-12-17 CA CA2933881A patent/CA2933881A1/en not_active Abandoned
- 2014-12-17 CN CN201480068499.8A patent/CN105899535A/zh active Pending
- 2014-12-17 AU AU2014364593A patent/AU2014364593A1/en not_active Abandoned
- 2014-12-17 KR KR1020167018822A patent/KR20160089532A/ko not_active Application Discontinuation
- 2014-12-17 US US14/574,197 patent/US20150210772A1/en not_active Abandoned
- 2014-12-17 RU RU2016128726A patent/RU2016128726A/ru unknown
-
2016
- 2016-06-13 IL IL246183A patent/IL246183A0/en unknown
-
2017
- 2017-07-28 US US15/662,684 patent/US20180171025A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20150210772A1 (en) | 2015-07-30 |
JP2017501157A (ja) | 2017-01-12 |
CN105899535A (zh) | 2016-08-24 |
SG11201604875PA (en) | 2016-07-28 |
WO2015095410A1 (en) | 2015-06-25 |
CA2933881A1 (en) | 2015-06-25 |
US20180171025A1 (en) | 2018-06-21 |
AU2014364593A1 (en) | 2016-07-07 |
BR112016013741A2 (pt) | 2017-10-03 |
EP3083690A1 (en) | 2016-10-26 |
KR20160089532A (ko) | 2016-07-27 |
RU2016128726A (ru) | 2018-01-23 |
IL246183A0 (en) | 2016-07-31 |
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