MX2016007376A - Regimen de dosificacion para un inhibidor selectivo alfa-isomorfo de fosfatidilinositol 3-quinasa. - Google Patents
Regimen de dosificacion para un inhibidor selectivo alfa-isomorfo de fosfatidilinositol 3-quinasa.Info
- Publication number
- MX2016007376A MX2016007376A MX2016007376A MX2016007376A MX2016007376A MX 2016007376 A MX2016007376 A MX 2016007376A MX 2016007376 A MX2016007376 A MX 2016007376A MX 2016007376 A MX2016007376 A MX 2016007376A MX 2016007376 A MX2016007376 A MX 2016007376A
- Authority
- MX
- Mexico
- Prior art keywords
- alpha
- kinase inhibitor
- dosage regimen
- isoform selective
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
La presente invención hace referencia a un compuesto inhibidor selectivo de la isomorfo alfa de la fosfatidilinositol 3-quinasa de formula (I) o una sal farmacéuticamente aceptable del mismo, para su uso en métodos útiles que tratan o previenen una enfermedad proliferativa en pacientes en necesidad del mismo mediante la administración oral de una cantidad terapéuticamente efectiva de dicho compuesto por al menos dos ciclos de cinco días consecutivos, en donde dicho compuesto no es administrado al paciente por un periodo de alrededor de dos días o alrededor de tres días entre dicho ciclo de cinco días consecutivos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13306679 | 2013-12-06 | ||
PCT/IB2014/066558 WO2015083101A1 (en) | 2013-12-06 | 2014-12-03 | Dosage regimen for an alpha-isoform selective phosphatidylinositol 3-kinase inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016007376A true MX2016007376A (es) | 2017-05-11 |
Family
ID=49876516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016007376A MX2016007376A (es) | 2013-12-06 | 2014-12-03 | Regimen de dosificacion para un inhibidor selectivo alfa-isomorfo de fosfatidilinositol 3-quinasa. |
Country Status (23)
Country | Link |
---|---|
US (4) | US20170000778A1 (es) |
EP (2) | EP3076969B1 (es) |
JP (1) | JP2016539149A (es) |
KR (1) | KR20160095035A (es) |
CN (1) | CN105979947A (es) |
AU (2) | AU2014358773A1 (es) |
BR (1) | BR112016011811A2 (es) |
CA (1) | CA2930359C (es) |
CL (1) | CL2016001361A1 (es) |
DK (1) | DK3076969T3 (es) |
ES (1) | ES2899167T3 (es) |
HK (1) | HK1223549A1 (es) |
HU (1) | HUE057092T2 (es) |
IL (1) | IL245709B (es) |
MX (1) | MX2016007376A (es) |
PH (1) | PH12016501026A1 (es) |
PL (1) | PL3076969T3 (es) |
PT (1) | PT3076969T (es) |
RU (1) | RU2680246C1 (es) |
SI (1) | SI3076969T1 (es) |
TN (1) | TN2016000179A1 (es) |
TW (1) | TWI666019B (es) |
WO (1) | WO2015083101A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3002954A1 (en) * | 2015-11-02 | 2017-05-11 | Novartis Ag | Dosage regimen for a phosphatidylinositol 3-kinase inhibitor |
WO2018060833A1 (en) * | 2016-09-27 | 2018-04-05 | Novartis Ag | Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib |
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-
2014
- 2014-12-03 AU AU2014358773A patent/AU2014358773A1/en not_active Abandoned
- 2014-12-03 CA CA2930359A patent/CA2930359C/en active Active
- 2014-12-03 HU HUE14812658A patent/HUE057092T2/hu unknown
- 2014-12-03 TN TN2016000179A patent/TN2016000179A1/en unknown
- 2014-12-03 BR BR112016011811A patent/BR112016011811A2/pt not_active Application Discontinuation
- 2014-12-03 MX MX2016007376A patent/MX2016007376A/es unknown
- 2014-12-03 KR KR1020167017707A patent/KR20160095035A/ko not_active Application Discontinuation
- 2014-12-03 RU RU2016126716A patent/RU2680246C1/ru active
- 2014-12-03 JP JP2016536539A patent/JP2016539149A/ja active Pending
- 2014-12-03 EP EP14812658.4A patent/EP3076969B1/en not_active Revoked
- 2014-12-03 DK DK14812658.4T patent/DK3076969T3/da active
- 2014-12-03 WO PCT/IB2014/066558 patent/WO2015083101A1/en active Application Filing
- 2014-12-03 CN CN201480074816.7A patent/CN105979947A/zh active Pending
- 2014-12-03 SI SI201431901T patent/SI3076969T1/sl unknown
- 2014-12-03 ES ES14812658T patent/ES2899167T3/es active Active
- 2014-12-03 EP EP21193406.2A patent/EP4000619A1/en not_active Withdrawn
- 2014-12-03 PT PT148126584T patent/PT3076969T/pt unknown
- 2014-12-03 US US15/101,155 patent/US20170000778A1/en not_active Abandoned
- 2014-12-03 PL PL14812658T patent/PL3076969T3/pl unknown
- 2014-12-05 TW TW103142503A patent/TWI666019B/zh not_active IP Right Cessation
-
2016
- 2016-05-18 IL IL245709A patent/IL245709B/en active IP Right Grant
- 2016-05-31 PH PH12016501026A patent/PH12016501026A1/en unknown
- 2016-06-03 CL CL2016001361A patent/CL2016001361A1/es unknown
- 2016-10-13 HK HK16111811.6A patent/HK1223549A1/zh unknown
-
2017
- 2017-09-29 US US15/719,636 patent/US10434092B2/en not_active Expired - Fee Related
- 2017-10-09 AU AU2017245292A patent/AU2017245292B2/en not_active Ceased
-
2019
- 2019-08-29 US US16/556,111 patent/US20200069670A1/en not_active Abandoned
-
2020
- 2020-11-25 US US17/105,453 patent/US20210196696A1/en not_active Abandoned
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