MX2012006072A - Composiciones y metodos para el diagnostico y el tratamiento de tumores. - Google Patents

Composiciones y metodos para el diagnostico y el tratamiento de tumores.

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Publication number
MX2012006072A
MX2012006072A MX2012006072A MX2012006072A MX2012006072A MX 2012006072 A MX2012006072 A MX 2012006072A MX 2012006072 A MX2012006072 A MX 2012006072A MX 2012006072 A MX2012006072 A MX 2012006072A MX 2012006072 A MX2012006072 A MX 2012006072A
Authority
MX
Mexico
Prior art keywords
tat211
seqid2
antibodies
treating
tumors expressing
Prior art date
Application number
MX2012006072A
Other languages
English (en)
Inventor
Paul Polakis
Mark Dennis
Bonnee Rubinfeld
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43856230&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012006072(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2012006072A publication Critical patent/MX2012006072A/es

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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

La presente invención está dirigida a composiciones de una materia útil para el diagnóstico y el tratamiento de un tumor en mamíferos y a métodos para usar esas composiciones de materia para el mismo propósito.
MX2012006072A 2009-11-30 2010-11-29 Composiciones y metodos para el diagnostico y el tratamiento de tumores. MX2012006072A (es)

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