MX2010003815A - Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un agente activo anti-bcl-2. - Google Patents
Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un agente activo anti-bcl-2.Info
- Publication number
- MX2010003815A MX2010003815A MX2010003815A MX2010003815A MX2010003815A MX 2010003815 A MX2010003815 A MX 2010003815A MX 2010003815 A MX2010003815 A MX 2010003815A MX 2010003815 A MX2010003815 A MX 2010003815A MX 2010003815 A MX2010003815 A MX 2010003815A
- Authority
- MX
- Mexico
- Prior art keywords
- bcl
- antibody
- type
- active agent
- combination therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
La presente invención se refiere al uso de un anticuerpo anti-CD2O de tipo II para la fabricación de un medicamento destinado al tratamiento del cáncer, en especial de los cánceres que expresan al CD20, en combinación con un agente activo anti-Bcl-2.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07020120 | 2007-10-15 | ||
PCT/EP2008/008635 WO2009049841A1 (en) | 2007-10-15 | 2008-10-13 | Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010003815A true MX2010003815A (es) | 2010-08-04 |
Family
ID=38904707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010003815A MX2010003815A (es) | 2007-10-15 | 2008-10-13 | Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un agente activo anti-bcl-2. |
Country Status (16)
Country | Link |
---|---|
US (6) | US20090098118A1 (es) |
EP (2) | EP2604277A1 (es) |
JP (1) | JP5416124B2 (es) |
KR (1) | KR101278395B1 (es) |
CN (1) | CN101827611B (es) |
AR (1) | AR068862A1 (es) |
AU (1) | AU2008314068B2 (es) |
BR (1) | BRPI0818673A2 (es) |
CA (1) | CA2702300A1 (es) |
CL (1) | CL2008003035A1 (es) |
IL (1) | IL204744A0 (es) |
MX (1) | MX2010003815A (es) |
PE (1) | PE20090966A1 (es) |
RU (1) | RU2541805C2 (es) |
TW (1) | TWI430809B (es) |
WO (1) | WO2009049841A1 (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI2380911T1 (en) * | 2003-11-05 | 2018-07-31 | Roche Glycart Ag | ANTIGEN-RELATED PATIENTS WITH INCREASED ATTENTION ON THE RECEPTOR FC AND EFFECTORAL FUNCTION |
US20110021440A1 (en) * | 2007-05-16 | 2011-01-27 | University Of Maryland, Baltimore | Apoptotic pathway targeting for the diagnosis and treatment of cancer |
TW201438738A (zh) | 2008-09-16 | 2014-10-16 | Genentech Inc | 治療進展型多發性硬化症之方法 |
WO2010043582A1 (en) * | 2008-10-17 | 2010-04-22 | Santaris Pharma A/S | Method for the treatment of cancer |
US8586754B2 (en) | 2008-12-05 | 2013-11-19 | Abbvie Inc. | BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
US20220315555A1 (en) | 2009-05-26 | 2022-10-06 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
SG175253A1 (en) * | 2009-05-26 | 2011-11-28 | Abbott Lab | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
EP2515883A4 (en) * | 2009-12-22 | 2013-07-17 | Abbvie Inc | CAPSULE OF ABT-263 |
EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
WO2012021486A2 (en) * | 2010-08-09 | 2012-02-16 | University Of South Florida | Acylsulfonamides and processes for producing the same |
WO2012020038A1 (en) | 2010-08-13 | 2012-02-16 | Roche Glycart Ag | Anti-tenascin-c a2 antibodies and methods of use |
RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
CA2819436A1 (en) * | 2010-12-16 | 2012-06-21 | Roche Glycart Ag | Combination therapy of an afucosylated cd20 antibody with a mdm2 inhibitor |
KR101274731B1 (ko) * | 2011-01-18 | 2013-06-18 | 동아대학교 산학협력단 | 레스베라트롤의 유사체인 hs-1793 또는 이의 약학적으로 허용가능한 염을 유효성분으로 하는 전립선 암 치료용 약학적 조성물 |
JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
JO3733B1 (ar) * | 2011-04-05 | 2021-01-31 | Bayer Ip Gmbh | استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة |
CN102222176A (zh) * | 2011-06-01 | 2011-10-19 | 山东大学 | 一种快速发现以Bcl-2蛋白为靶点的先导化合物的方法 |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
LT2791160T (lt) | 2011-12-16 | 2022-06-10 | Modernatx, Inc. | Modifikuotos mrnr sudėtys |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9192651B2 (en) | 2012-04-02 | 2015-11-24 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of secreted proteins |
JP6408993B2 (ja) * | 2012-09-07 | 2018-10-17 | ジェネンテック, インコーポレイテッド | タイプII抗CD20抗体と選択的Bcl−2インヒビターの併用療法 |
WO2014081507A1 (en) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Terminally modified rna |
US20150313906A1 (en) * | 2012-12-19 | 2015-11-05 | Glaxosmithkline Llc | Combination |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
CA2926218A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
CA2984706A1 (en) * | 2015-05-26 | 2016-12-01 | F. Hoffmann-La Roche Ag | Combination therapy of an anti cd20 antibody with a bcl-2 inhibitor and a mdm2 inhibitor |
EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
TR201703149A2 (tr) * | 2017-03-01 | 2018-09-21 | Univ Yeditepe | Kemoterapi̇k i̇laç kompozi̇syonu |
US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
CN110869391A (zh) * | 2017-07-26 | 2020-03-06 | 豪夫迈·罗氏有限公司 | 用BET抑制剂,Bcl-2抑制剂和抗CD20抗体的组合疗法 |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
GEP20237460B (en) * | 2018-07-31 | 2023-01-25 | Ascentage Pharma Suzhou Co Ltd | Synergistic antitumor effect of bcl-2 inhibitor combined with rituximab and/or bendamustine or bcl-2 inhibitor combined with chop |
WO2020106757A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
SG11202113356XA (en) | 2019-06-12 | 2021-12-30 | Juno Therapeutics Inc | Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein |
EP3870261B1 (en) | 2019-12-13 | 2024-01-31 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
CN115996760A (zh) * | 2020-04-27 | 2023-04-21 | 阿鲁纳生物股份公司 | 用于中枢神经***递送的结合剂及其用途 |
WO2022133030A1 (en) | 2020-12-16 | 2022-06-23 | Juno Therapeutics, Inc. | Combination therapy of a cell therapy and a bcl2 inhibitor |
WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US371191A (en) | 1887-10-11 | Cloth-sponging machine | ||
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
US5734033A (en) * | 1988-12-22 | 1998-03-31 | The Trustees Of The University Of Pennsylvania | Antisense oligonucleotides inhibiting human bcl-2 gene expression |
US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
EP0722342B1 (en) | 1993-09-20 | 2004-12-29 | The Trustees Of The University Of Pennsylvania | REGULATION OF bcl-2 GENE EXPRESSION |
EP1067956B1 (en) | 1998-04-03 | 2007-03-14 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
ATE458007T1 (de) * | 1998-04-20 | 2010-03-15 | Glycart Biotechnology Ag | Glykosylierungs-engineering von antikörpern zur verbesserung der antikörperabhängigen zellvermittelten zytotoxizität |
EP1080113A4 (en) | 1998-05-15 | 2002-04-17 | Imclone Systems Inc | TREATMENT OF HUMAN TUMORS USING RADIATION AND GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS |
US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
RU2306952C2 (ru) * | 2001-01-31 | 2007-09-27 | Байоджен Айдек Инк. | Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами |
US7432304B2 (en) * | 2001-05-30 | 2008-10-07 | The Regents Of The University Of Michigan | Small molecule antagonists of Bcl-2 family proteins |
NZ581541A (en) | 2002-10-17 | 2011-07-29 | Genmab As | Human monoclonal antibodies against CD20 |
CN103833854B (zh) | 2002-12-16 | 2017-12-12 | 健泰科生物技术公司 | 免疫球蛋白变体及其用途 |
WO2004056971A2 (en) | 2002-12-19 | 2004-07-08 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
PL224786B1 (pl) | 2003-01-22 | 2017-01-31 | Glycart Biotechnology Ag | Wyizolowany kwas nukleinowy, ssaczy wektor ekspresyjny, komórki gospodarza, fuzja polipeptydowa i sposób jej wytwarzania, sposoby in vitro i ex vivo modyfikowania profilu glikozylacji polipeptydu wytwarzanego przez komórki gospodarza |
KR101168441B1 (ko) | 2003-05-30 | 2012-07-25 | 게민 엑스 파마슈티컬스 캐나다 인코포레이티드 | 암 또는 바이러스 질환의 치료를 위한 삼복소환 화합물,조성물 및 방법 |
EP2236172A1 (en) * | 2003-11-04 | 2010-10-06 | Novartis Vaccines and Diagnostics, Inc. | Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers |
SI2380911T1 (en) * | 2003-11-05 | 2018-07-31 | Roche Glycart Ag | ANTIGEN-RELATED PATIENTS WITH INCREASED ATTENTION ON THE RECEPTOR FC AND EFFECTORAL FUNCTION |
EA011218B1 (ru) * | 2004-03-25 | 2009-02-27 | Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган | Сокристаллы госсипола и их применение |
EP1740946B1 (en) | 2004-04-20 | 2013-11-06 | Genmab A/S | Human monoclonal antibodies against cd20 |
EP1853255A4 (en) | 2005-02-22 | 2009-07-08 | Gemin X Pharmaceuticals Canada | METHODS FOR TREATING ARTHRITIS USING TRIHETEROCYCLIC COMPOUNDS |
WO2006099667A1 (en) | 2005-03-21 | 2006-09-28 | The Walter And Eliza Hall Institute Of Medical Research | Prophylactic and therapeutic agents and uses therefor |
CN101175738B (zh) * | 2005-05-12 | 2010-10-27 | 雅培制药有限公司 | 细胞凋亡促进剂 |
BRPI0611220A2 (pt) * | 2005-06-02 | 2010-08-24 | Astrazeneca Ab | anticorpos direcionados para cd20 e usos dos mesmos |
NO345919B1 (no) | 2005-08-26 | 2021-10-18 | Roche Glycart Ag | Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet |
-
2008
- 2008-09-22 US US12/234,739 patent/US20090098118A1/en not_active Abandoned
- 2008-10-13 EP EP13155433.9A patent/EP2604277A1/en not_active Withdrawn
- 2008-10-13 KR KR1020107008152A patent/KR101278395B1/ko not_active IP Right Cessation
- 2008-10-13 EP EP08839967A patent/EP2203185A1/en not_active Withdrawn
- 2008-10-13 CN CN200880111728.4A patent/CN101827611B/zh not_active Expired - Fee Related
- 2008-10-13 WO PCT/EP2008/008635 patent/WO2009049841A1/en active Application Filing
- 2008-10-13 AU AU2008314068A patent/AU2008314068B2/en not_active Ceased
- 2008-10-13 JP JP2010528326A patent/JP5416124B2/ja not_active Expired - Fee Related
- 2008-10-13 RU RU2010118448/15A patent/RU2541805C2/ru not_active IP Right Cessation
- 2008-10-13 BR BRPI0818673A patent/BRPI0818673A2/pt not_active IP Right Cessation
- 2008-10-13 MX MX2010003815A patent/MX2010003815A/es active IP Right Grant
- 2008-10-13 CA CA2702300A patent/CA2702300A1/en not_active Abandoned
- 2008-10-14 AR ARP080104472A patent/AR068862A1/es unknown
- 2008-10-14 CL CL2008003035A patent/CL2008003035A1/es unknown
- 2008-10-14 PE PE2008001762A patent/PE20090966A1/es not_active Application Discontinuation
- 2008-10-14 TW TW097139389A patent/TWI430809B/zh not_active IP Right Cessation
-
2010
- 2010-03-25 IL IL204744A patent/IL204744A0/en unknown
- 2010-05-14 US US12/780,640 patent/US20110086025A1/en not_active Abandoned
-
2011
- 2011-07-26 US US13/190,752 patent/US20110287006A1/en not_active Abandoned
-
2012
- 2012-03-20 US US13/424,506 patent/US20120276085A1/en not_active Abandoned
-
2013
- 2013-01-31 US US13/756,319 patent/US20140004104A1/en not_active Abandoned
-
2014
- 2014-03-27 US US14/227,728 patent/US20150056186A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2702300A1 (en) | 2009-04-23 |
CL2008003035A1 (es) | 2010-01-11 |
AR068862A1 (es) | 2009-12-09 |
EP2604277A1 (en) | 2013-06-19 |
CN101827611A (zh) | 2010-09-08 |
TW200920401A (en) | 2009-05-16 |
IL204744A0 (en) | 2010-11-30 |
CN101827611B (zh) | 2014-01-15 |
US20110086025A1 (en) | 2011-04-14 |
WO2009049841A1 (en) | 2009-04-23 |
EP2203185A1 (en) | 2010-07-07 |
RU2010118448A (ru) | 2012-05-20 |
PE20090966A1 (es) | 2009-07-13 |
US20150056186A1 (en) | 2015-02-26 |
AU2008314068A1 (en) | 2009-04-23 |
KR101278395B1 (ko) | 2013-06-24 |
AU2008314068B2 (en) | 2014-01-16 |
TWI430809B (zh) | 2014-03-21 |
BRPI0818673A2 (pt) | 2015-09-08 |
JP5416124B2 (ja) | 2014-02-12 |
US20140004104A1 (en) | 2014-01-02 |
KR20100056559A (ko) | 2010-05-27 |
US20120276085A1 (en) | 2012-11-01 |
US20110287006A1 (en) | 2011-11-24 |
JP2011500521A (ja) | 2011-01-06 |
US20090098118A1 (en) | 2009-04-16 |
RU2541805C2 (ru) | 2015-02-20 |
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