CL2008003035A1 - Uso de un anticuerpo anti cd-20 de tipo 2 que sirve para preparar un medicamento, que en conjunto con un agente activo anti-bcl-2, permite tratar un cancer que exprese el cd 20. - Google Patents
Uso de un anticuerpo anti cd-20 de tipo 2 que sirve para preparar un medicamento, que en conjunto con un agente activo anti-bcl-2, permite tratar un cancer que exprese el cd 20.Info
- Publication number
- CL2008003035A1 CL2008003035A1 CL2008003035A CL2008003035A CL2008003035A1 CL 2008003035 A1 CL2008003035 A1 CL 2008003035A1 CL 2008003035 A CL2008003035 A CL 2008003035A CL 2008003035 A CL2008003035 A CL 2008003035A CL 2008003035 A1 CL2008003035 A1 CL 2008003035A1
- Authority
- CL
- Chile
- Prior art keywords
- expresses
- cancer
- drug
- prepare
- active agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
Uso de un anticuerpo anti cd-20 de tipo 2 que sirve para preparar un medicamento, que en conjunto con un agente activo anti-bel-2, permite tratar un cáncer que exprese el cd 20.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07020120 | 2007-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003035A1 true CL2008003035A1 (es) | 2010-01-11 |
Family
ID=38904707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003035A CL2008003035A1 (es) | 2007-10-15 | 2008-10-14 | Uso de un anticuerpo anti cd-20 de tipo 2 que sirve para preparar un medicamento, que en conjunto con un agente activo anti-bcl-2, permite tratar un cancer que exprese el cd 20. |
Country Status (16)
Country | Link |
---|---|
US (6) | US20090098118A1 (es) |
EP (2) | EP2203185A1 (es) |
JP (1) | JP5416124B2 (es) |
KR (1) | KR101278395B1 (es) |
CN (1) | CN101827611B (es) |
AR (1) | AR068862A1 (es) |
AU (1) | AU2008314068B2 (es) |
BR (1) | BRPI0818673A2 (es) |
CA (1) | CA2702300A1 (es) |
CL (1) | CL2008003035A1 (es) |
IL (1) | IL204744A0 (es) |
MX (1) | MX2010003815A (es) |
PE (1) | PE20090966A1 (es) |
RU (1) | RU2541805C2 (es) |
TW (1) | TWI430809B (es) |
WO (1) | WO2009049841A1 (es) |
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ME03330B (me) * | 2003-11-05 | 2019-10-20 | Roche Glycart Ag | Cd20 antitijela sa povećanim afinitetom za vezivanje fc receptora i efektornom funkcijom |
US20110021440A1 (en) * | 2007-05-16 | 2011-01-27 | University Of Maryland, Baltimore | Apoptotic pathway targeting for the diagnosis and treatment of cancer |
TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
WO2010043582A1 (en) * | 2008-10-17 | 2010-04-22 | Santaris Pharma A/S | Method for the treatment of cancer |
US8586754B2 (en) | 2008-12-05 | 2013-11-19 | Abbvie Inc. | BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases |
US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
TWI561523B (en) * | 2009-05-26 | 2016-12-11 | Abbvie Bahamas Ltd | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
US20220315555A1 (en) | 2009-05-26 | 2022-10-06 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
AR078161A1 (es) * | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
KR20120098915A (ko) * | 2009-12-22 | 2012-09-05 | 아보트 러보러터리즈 | Abt?263 캡슐제 |
EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
WO2012021486A2 (en) * | 2010-08-09 | 2012-02-16 | University Of South Florida | Acylsulfonamides and processes for producing the same |
MX2013001336A (es) | 2010-08-13 | 2013-03-08 | Roche Glycart Ag | Anticuerpos ani-tenascina c a2 y metodos de utilizacion. |
NZ608972A (en) | 2010-10-01 | 2015-09-25 | Moderna Therapeutics Inc | Engineered nucleic acids and methods of use thereof |
KR20130088170A (ko) * | 2010-12-16 | 2013-08-07 | 로슈 글리카트 아게 | 비푸코실화 cd20 항체와 mdm2 저해제와의 조합 치료 |
KR101274731B1 (ko) * | 2011-01-18 | 2013-06-18 | 동아대학교 산학협력단 | 레스베라트롤의 유사체인 hs-1793 또는 이의 약학적으로 허용가능한 염을 유효성분으로 하는 전립선 암 치료용 약학적 조성물 |
US8710200B2 (en) | 2011-03-31 | 2014-04-29 | Moderna Therapeutics, Inc. | Engineered nucleic acids encoding a modified erythropoietin and their expression |
JO3733B1 (ar) * | 2011-04-05 | 2021-01-31 | Bayer Ip Gmbh | استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة |
CN102222176A (zh) * | 2011-06-01 | 2011-10-19 | 山东大学 | 一种快速发现以Bcl-2蛋白为靶点的先导化合物的方法 |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
CA2850624A1 (en) | 2011-10-03 | 2013-04-11 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
CN110201187A (zh) | 2011-12-16 | 2019-09-06 | 现代泰克斯公司 | 经修饰的核苷、核苷酸和核酸组合物 |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
AU2013243952A1 (en) | 2012-04-02 | 2014-10-30 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9539251B2 (en) | 2012-09-07 | 2017-01-10 | Genentech, Inc. | Combination therapy of a type II anti-CD20 antibody with a selective Bcl-2 inhibitor |
PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
EP2934531A4 (en) * | 2012-12-19 | 2016-06-15 | Glaxosmithkline Llc | COMBINATION |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
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US10323076B2 (en) | 2013-10-03 | 2019-06-18 | Modernatx, Inc. | Polynucleotides encoding low density lipoprotein receptor |
WO2016188935A1 (en) * | 2015-05-26 | 2016-12-01 | F. Hoffmann-La Roche Ag | Combination therapy of an anti cd20 antibody with a bcl-2 inhibitor and a mdm2 inhibitor |
JP2020508436A (ja) | 2016-12-07 | 2020-03-19 | プロジェニティ, インコーポレイテッド | 胃腸管の検出方法、装置およびシステム |
TR201703149A2 (tr) * | 2017-03-01 | 2018-09-21 | Univ Yeditepe | Kemoterapi̇k i̇laç kompozi̇syonu |
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CN110869391A (zh) * | 2017-07-26 | 2020-03-06 | 豪夫迈·罗氏有限公司 | 用BET抑制剂,Bcl-2抑制剂和抗CD20抗体的组合疗法 |
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US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
BR112020019134A2 (pt) * | 2018-07-31 | 2021-02-09 | Ascentage Pharma (Suzhou) Co., Ltd. | produtos de combinação que compreendem inibidor de bcl-2 e mab anti-cd20, ou inibidor de bcl-2, mab anti-cd20 e bendamustina, ou inibidor de bcl-2 e chop e usos terapêuticos dos mesmos |
CN116726362A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
CA3142361A1 (en) | 2019-06-12 | 2020-12-17 | Juno Therapeutics, Inc. | Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein |
EP4309722A2 (en) | 2019-12-13 | 2024-01-24 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
CA3176495A1 (en) * | 2020-04-27 | 2021-11-04 | Aruna Bio, Inc. | Binding agents and uses thereof for central nervous system delivery |
WO2022133030A1 (en) | 2020-12-16 | 2022-06-23 | Juno Therapeutics, Inc. | Combination therapy of a cell therapy and a bcl2 inhibitor |
WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
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US7850962B2 (en) | 2004-04-20 | 2010-12-14 | Genmab A/S | Human monoclonal antibodies against CD20 |
EP1853255A4 (en) | 2005-02-22 | 2009-07-08 | Gemin X Pharmaceuticals Canada | METHODS FOR TREATING ARTHRITIS USING TRIHETEROCYCLIC COMPOUNDS |
WO2006099667A1 (en) | 2005-03-21 | 2006-09-28 | The Walter And Eliza Hall Institute Of Medical Research | Prophylactic and therapeutic agents and uses therefor |
JP5132550B2 (ja) * | 2005-05-12 | 2013-01-30 | アボット・ラボラトリーズ | アポトーシス促進剤 |
CN101282993A (zh) * | 2005-06-02 | 2008-10-08 | 阿斯利康公司 | 针对cd20的抗体和其用途 |
KR101460932B1 (ko) | 2005-08-26 | 2014-11-12 | 로슈 글리카트 아게 | 변형된 세포 신호 활성을 가진 개질된 항원 결합 분자 |
-
2008
- 2008-09-22 US US12/234,739 patent/US20090098118A1/en not_active Abandoned
- 2008-10-13 KR KR1020107008152A patent/KR101278395B1/ko not_active IP Right Cessation
- 2008-10-13 JP JP2010528326A patent/JP5416124B2/ja not_active Expired - Fee Related
- 2008-10-13 AU AU2008314068A patent/AU2008314068B2/en not_active Ceased
- 2008-10-13 BR BRPI0818673A patent/BRPI0818673A2/pt not_active IP Right Cessation
- 2008-10-13 EP EP08839967A patent/EP2203185A1/en not_active Withdrawn
- 2008-10-13 CA CA2702300A patent/CA2702300A1/en not_active Abandoned
- 2008-10-13 CN CN200880111728.4A patent/CN101827611B/zh not_active Expired - Fee Related
- 2008-10-13 EP EP13155433.9A patent/EP2604277A1/en not_active Withdrawn
- 2008-10-13 RU RU2010118448/15A patent/RU2541805C2/ru not_active IP Right Cessation
- 2008-10-13 WO PCT/EP2008/008635 patent/WO2009049841A1/en active Application Filing
- 2008-10-13 MX MX2010003815A patent/MX2010003815A/es active IP Right Grant
- 2008-10-14 CL CL2008003035A patent/CL2008003035A1/es unknown
- 2008-10-14 PE PE2008001762A patent/PE20090966A1/es not_active Application Discontinuation
- 2008-10-14 TW TW097139389A patent/TWI430809B/zh not_active IP Right Cessation
- 2008-10-14 AR ARP080104472A patent/AR068862A1/es unknown
-
2010
- 2010-03-25 IL IL204744A patent/IL204744A0/en unknown
- 2010-05-14 US US12/780,640 patent/US20110086025A1/en not_active Abandoned
-
2011
- 2011-07-26 US US13/190,752 patent/US20110287006A1/en not_active Abandoned
-
2012
- 2012-03-20 US US13/424,506 patent/US20120276085A1/en not_active Abandoned
-
2013
- 2013-01-31 US US13/756,319 patent/US20140004104A1/en not_active Abandoned
-
2014
- 2014-03-27 US US14/227,728 patent/US20150056186A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX2010003815A (es) | 2010-08-04 |
AU2008314068A1 (en) | 2009-04-23 |
US20090098118A1 (en) | 2009-04-16 |
RU2010118448A (ru) | 2012-05-20 |
RU2541805C2 (ru) | 2015-02-20 |
WO2009049841A1 (en) | 2009-04-23 |
AU2008314068B2 (en) | 2014-01-16 |
KR101278395B1 (ko) | 2013-06-24 |
TWI430809B (zh) | 2014-03-21 |
CN101827611A (zh) | 2010-09-08 |
JP2011500521A (ja) | 2011-01-06 |
AR068862A1 (es) | 2009-12-09 |
US20110086025A1 (en) | 2011-04-14 |
BRPI0818673A2 (pt) | 2015-09-08 |
CN101827611B (zh) | 2014-01-15 |
EP2203185A1 (en) | 2010-07-07 |
US20150056186A1 (en) | 2015-02-26 |
JP5416124B2 (ja) | 2014-02-12 |
TW200920401A (en) | 2009-05-16 |
US20120276085A1 (en) | 2012-11-01 |
CA2702300A1 (en) | 2009-04-23 |
US20110287006A1 (en) | 2011-11-24 |
KR20100056559A (ko) | 2010-05-27 |
PE20090966A1 (es) | 2009-07-13 |
IL204744A0 (en) | 2010-11-30 |
US20140004104A1 (en) | 2014-01-02 |
EP2604277A1 (en) | 2013-06-19 |
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