MA54862A - Procédé de préparation d'un agoniste double gip/glp1 - Google Patents
Procédé de préparation d'un agoniste double gip/glp1Info
- Publication number
- MA54862A MA54862A MA054862A MA54862A MA54862A MA 54862 A MA54862 A MA 54862A MA 054862 A MA054862 A MA 054862A MA 54862 A MA54862 A MA 54862A MA 54862 A MA54862 A MA 54862A
- Authority
- MA
- Morocco
- Prior art keywords
- gip
- preparing
- dual agonist
- glp1 dual
- glp1
- Prior art date
Links
- 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 title 1
- 108091016366 Histone-lysine N-methyltransferase EHMT1 Proteins 0.000 title 1
- 229940125542 dual agonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
- C07C7/04—Purification; Separation; Use of additives by distillation
- C07C7/05—Purification; Separation; Use of additives by distillation with the aid of auxiliary compounds
- C07C7/06—Purification; Separation; Use of additives by distillation with the aid of auxiliary compounds by azeotropic distillation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Water Supply & Treatment (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962797963P | 2019-01-29 | 2019-01-29 | |
US201962815053P | 2019-03-07 | 2019-03-07 | |
US201962818342P | 2019-03-14 | 2019-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA54862A true MA54862A (fr) | 2022-05-04 |
Family
ID=69724140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA054862A MA54862A (fr) | 2019-01-29 | 2020-01-28 | Procédé de préparation d'un agoniste double gip/glp1 |
Country Status (18)
Country | Link |
---|---|
US (1) | US20220135639A1 (fr) |
EP (1) | EP3917950A1 (fr) |
JP (2) | JP7315683B2 (fr) |
KR (1) | KR20210110349A (fr) |
CN (1) | CN113330024A (fr) |
AU (3) | AU2020216922A1 (fr) |
BR (1) | BR112021012368A2 (fr) |
CA (2) | CA3224820A1 (fr) |
CL (1) | CL2021001905A1 (fr) |
CO (1) | CO2021009662A2 (fr) |
EC (1) | ECSP21056124A (fr) |
IL (1) | IL284446A (fr) |
MA (1) | MA54862A (fr) |
MX (1) | MX2021008965A (fr) |
PE (1) | PE20211992A1 (fr) |
SG (1) | SG11202107123TA (fr) |
TW (1) | TWI799680B (fr) |
WO (1) | WO2020159949A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110642935A (zh) * | 2019-09-25 | 2020-01-03 | 成都奥达生物科技有限公司 | 一种替瑞帕肽类似物 |
CA3200881A1 (fr) * | 2020-12-02 | 2022-06-09 | Zhixiang PAN | Composes polypeptidiques modifies par lactame |
WO2022159395A1 (fr) * | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions et procédés pour le traitement de troubles métaboliques et hépatiques |
CN117866050A (zh) * | 2021-05-28 | 2024-04-12 | 广东众生睿创生物科技有限公司 | 多肽的制备及其应用 |
WO2023089594A1 (fr) | 2021-11-22 | 2023-05-25 | Sun Pharmaceutical Industries Limited | Procédé de préparation de tirzépatide ou de sel pharmaceutiquement acceptable de celui-ci |
TW202404996A (zh) | 2022-04-04 | 2024-02-01 | 美商美國禮來大藥廠 | 製備glp-1/升糖素雙重促效劑之方法 |
CN116023444B (zh) * | 2022-08-12 | 2023-08-01 | 重庆宸安生物制药有限公司 | 一种gip和glp-1双受体激动剂多肽化合物及其应用 |
WO2024077149A2 (fr) * | 2022-10-05 | 2024-04-11 | Eli Lilly And Company | Peptides pour la synthèse d'incrétine |
WO2024112617A2 (fr) | 2022-11-21 | 2024-05-30 | Eli Lilly And Company | Procédé de préparation d'un double agoniste gip/glp1 |
WO2024134676A1 (fr) * | 2022-12-19 | 2024-06-27 | Dr. Reddy’S Laboratories Limited | Procédé de préparation de tirzépatide |
KR20240102887A (ko) * | 2022-12-23 | 2024-07-03 | 한미약품 주식회사 | 신규한 glp-1, gip, 및 글루카곤 수용체 모두에 활성을 갖는 삼중 활성체 및 이를 포함하는 비만의 예방 또는 치료용 약학적 조성물 |
CN116731154A (zh) * | 2023-08-14 | 2023-09-12 | 苏州金顶生物有限公司 | 一种全液相法制备替西帕肽的方法 |
CN117736273B (zh) * | 2023-12-08 | 2024-05-07 | 广东省卓肽医药有限公司 | 一种替尔泊肽的纯化方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1076066A1 (fr) * | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides abaissant le taux de glucose sanguin |
CN102414220A (zh) * | 2009-05-01 | 2012-04-11 | 霍夫曼-拉罗奇有限公司 | 使用固相和液相组合技术的促胰岛素肽合成 |
JOP20200119A1 (ar) | 2015-01-09 | 2017-06-16 | Lilly Co Eli | مركبات مساعد مشترك من gip وglp-1 |
CN106928086B (zh) * | 2015-12-31 | 2019-05-31 | 深圳翰宇药业股份有限公司 | 一种长链化合物的制备方法 |
-
2020
- 2020-01-22 TW TW109102657A patent/TWI799680B/zh active
- 2020-01-28 CA CA3224820A patent/CA3224820A1/fr active Pending
- 2020-01-28 EP EP20707971.6A patent/EP3917950A1/fr active Pending
- 2020-01-28 AU AU2020216922A patent/AU2020216922A1/en not_active Abandoned
- 2020-01-28 KR KR1020217024133A patent/KR20210110349A/ko not_active Application Discontinuation
- 2020-01-28 US US17/310,247 patent/US20220135639A1/en active Pending
- 2020-01-28 CA CA3128023A patent/CA3128023A1/fr active Pending
- 2020-01-28 CN CN202080011536.7A patent/CN113330024A/zh active Pending
- 2020-01-28 BR BR112021012368-7A patent/BR112021012368A2/pt unknown
- 2020-01-28 PE PE2021001218A patent/PE20211992A1/es unknown
- 2020-01-28 MX MX2021008965A patent/MX2021008965A/es unknown
- 2020-01-28 JP JP2021542153A patent/JP7315683B2/ja active Active
- 2020-01-28 MA MA054862A patent/MA54862A/fr unknown
- 2020-01-28 WO PCT/US2020/015353 patent/WO2020159949A1/fr unknown
- 2020-01-28 SG SG11202107123TA patent/SG11202107123TA/en unknown
-
2021
- 2021-06-28 IL IL284446A patent/IL284446A/en unknown
- 2021-07-19 CL CL2021001905A patent/CL2021001905A1/es unknown
- 2021-07-23 CO CONC2021/0009662A patent/CO2021009662A2/es unknown
- 2021-07-29 EC ECSENADI202156124A patent/ECSP21056124A/es unknown
-
2023
- 2023-02-16 JP JP2023022752A patent/JP2023078130A/ja active Pending
- 2023-05-15 AU AU2023203001A patent/AU2023203001B2/en active Active
-
2024
- 2024-02-16 AU AU2024201004A patent/AU2024201004A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2020216922A1 (en) | 2021-07-15 |
TWI799680B (zh) | 2023-04-21 |
CN113330024A (zh) | 2021-08-31 |
CA3224820A1 (fr) | 2020-08-06 |
BR112021012368A2 (pt) | 2021-09-14 |
MX2021008965A (es) | 2021-08-24 |
AU2024201004A1 (en) | 2024-03-07 |
IL284446A (en) | 2021-08-31 |
US20220135639A1 (en) | 2022-05-05 |
JP2023078130A (ja) | 2023-06-06 |
KR20210110349A (ko) | 2021-09-07 |
WO2020159949A1 (fr) | 2020-08-06 |
PE20211992A1 (es) | 2021-10-18 |
JP7315683B2 (ja) | 2023-07-26 |
ECSP21056124A (es) | 2021-08-31 |
CL2021001905A1 (es) | 2022-03-11 |
AU2023203001A1 (en) | 2023-06-08 |
CA3128023A1 (fr) | 2020-08-06 |
EP3917950A1 (fr) | 2021-12-08 |
AU2023203001B2 (en) | 2024-03-28 |
JP2022517834A (ja) | 2022-03-10 |
CO2021009662A2 (es) | 2021-08-09 |
TW202043260A (zh) | 2020-12-01 |
SG11202107123TA (en) | 2021-08-30 |
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