MA39804A - Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin - Google Patents

Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin

Info

Publication number
MA39804A
MA39804A MA039804A MA39804A MA39804A MA 39804 A MA39804 A MA 39804A MA 039804 A MA039804 A MA 039804A MA 39804 A MA39804 A MA 39804A MA 39804 A MA39804 A MA 39804A
Authority
MA
Morocco
Prior art keywords
methods
inflammatory bowel
diagnosing
bowel disease
treating inflammatory
Prior art date
Application number
MA039804A
Other languages
English (en)
Inventor
Jason A Hackney
Mary Keir
Gaik Wei Tew
Original Assignee
Hoffmann La Roche
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Genentech Inc filed Critical Hoffmann La Roche
Publication of MA39804A publication Critical patent/MA39804A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

L'invention porte sur des biomarqueurs prédictifs de la réactivité aux antagonistes de l'intégrine bêta 7, y compris des anticorps de sous-unité de l'intégrine anti-bêta 7, et sur des procédés d'utilisation de tels biomarqueurs. De plus, l'invention concerne des méthodes de traitement de troubles inflammatoires gastro-intestinaux, tels que les maladies inflammatoires de l'intestin, y compris la colite ulcéreuse et la maladie de crohn. L'invention concerne également des méthodes d'utilisation de tels biomarqueurs prédictifs pour le traitement de maladies inflammatoires de l'intestin, y compris la colite ulcéreuse et la maladie de crohn.
MA039804A 2014-03-27 2015-03-26 Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin MA39804A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461971379P 2014-03-27 2014-03-27

Publications (1)

Publication Number Publication Date
MA39804A true MA39804A (fr) 2017-02-01

Family

ID=54196399

Family Applications (1)

Application Number Title Priority Date Filing Date
MA039804A MA39804A (fr) 2014-03-27 2015-03-26 Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin

Country Status (15)

Country Link
US (4) US10273542B2 (fr)
EP (1) EP3122377A4 (fr)
JP (3) JP7054990B2 (fr)
KR (2) KR102397324B1 (fr)
CN (2) CN106102767B (fr)
AR (1) AR099856A1 (fr)
AU (3) AU2015235986B2 (fr)
BR (1) BR112016020053A2 (fr)
CA (1) CA2939246A1 (fr)
IL (2) IL247266B (fr)
MA (1) MA39804A (fr)
MX (2) MX2016012282A (fr)
RU (1) RU2016136716A (fr)
SG (1) SG11201607938UA (fr)
WO (1) WO2015148809A1 (fr)

Families Citing this family (12)

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JP6219556B2 (ja) * 2008-05-16 2017-10-25 ジェネンテック， インコーポレイテッド ベータ７インテグリンアンタゴニストを用いた消化管炎症性障害の治療評価のためのバイオマーカーの使用
MX2016012282A (es) 2014-03-27 2017-01-06 Genentech Inc Metodos para diagnosticar y tratar enfermedad inflamatoria de intestino.
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CN107083423B (zh) * 2017-03-27 2022-01-28 北京极客基因科技有限公司 一种药物靶点预测和药物全方面评价方法
WO2019200202A1 (fr) 2018-04-12 2019-10-17 Morphic Therapeutic, Inc. Antagonistes de l'intégrine humaine (alpha4) (beta7)
EP3884276A2 (fr) * 2018-11-23 2021-09-29 Katholieke Universiteit Leuven Prédiction d'une réponse à un traitement dans une maladie intestinale inflammatoire
JP2022523564A (ja) 2019-03-04 2022-04-25 アイオーカレンツ， インコーポレイテッド 機械学習を使用するデータ圧縮および通信
UY38926A (es) 2019-10-16 2021-05-31 Morphic Therapeutic Inc INHIBICIÓN DE INTEGRINA alfa4beta7 HUMANA
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WO2023061502A1 (fr) * 2021-10-15 2023-04-20 苏州生物医药转化工程中心 Molécule de liaison bispécifique
CN114085908B (zh) * 2021-10-30 2023-08-08 中国人民解放军陆军军医大学第一附属医院 用于评估胶质母细胞瘤治疗效果的基因靶点组合及其应用

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Publication number Publication date
AU2015235986B2 (en) 2020-12-03
JP2020062013A (ja) 2020-04-23
KR20220065091A (ko) 2022-05-19
US10669587B2 (en) 2020-06-02
US20190256913A1 (en) 2019-08-22
AU2021203296A1 (en) 2021-06-17
US10273542B2 (en) 2019-04-30
IL276516A (en) 2020-09-30
CN113604543A (zh) 2021-11-05
AU2021200518B2 (en) 2021-03-04
US20220186314A1 (en) 2022-06-16
AU2021200518A1 (en) 2021-02-25
US20200325538A1 (en) 2020-10-15
JP2017511131A (ja) 2017-04-20
WO2015148809A1 (fr) 2015-10-01
IL247266B (en) 2020-08-31
SG11201607938UA (en) 2016-10-28
US11261493B2 (en) 2022-03-01
CA2939246A1 (fr) 2015-10-01
CN106102767A (zh) 2016-11-09
RU2016136716A (ru) 2018-04-28
US20170233809A1 (en) 2017-08-17
KR20160130780A (ko) 2016-11-14
BR112016020053A2 (pt) 2018-02-20
EP3122377A1 (fr) 2017-02-01
KR102397324B1 (ko) 2022-05-13
AU2015235986A1 (en) 2016-08-25
CN106102767B (zh) 2021-08-10
JP7054990B2 (ja) 2022-04-15
MX2022010809A (es) 2022-09-27
MX2016012282A (es) 2017-01-06
JP2022043033A (ja) 2022-03-15
EP3122377A4 (fr) 2018-03-14
AR099856A1 (es) 2016-08-24
IL247266A0 (en) 2016-09-29

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