MA26913A1 - Derives de beta-amino acide nitrile. - Google Patents
Derives de beta-amino acide nitrile.Info
- Publication number
- MA26913A1 MA26913A1 MA26950A MA26950A MA26913A1 MA 26913 A1 MA26913 A1 MA 26913A1 MA 26950 A MA26950 A MA 26950A MA 26950 A MA26950 A MA 26950A MA 26913 A1 MA26913 A1 MA 26913A1
- Authority
- MA
- Morocco
- Prior art keywords
- amino derivatives
- acid beta
- nitrile acid
- nitrile
- beta
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000002825 nitriles Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
- C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
- C07C255/44—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms at least one of the singly-bound nitrogen atoms being acylated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00112577 | 2000-06-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA26913A1 true MA26913A1 (fr) | 2004-12-20 |
Family
ID=8168969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA26950A MA26913A1 (fr) | 2000-06-14 | 2002-12-13 | Derives de beta-amino acide nitrile. |
Country Status (29)
Country | Link |
---|---|
US (1) | US6462076B2 (fr) |
EP (1) | EP1294679B1 (fr) |
JP (1) | JP3872427B2 (fr) |
KR (1) | KR20030029057A (fr) |
CN (1) | CN1324006C (fr) |
AR (1) | AR031594A1 (fr) |
AT (1) | ATE304997T1 (fr) |
AU (2) | AU2001266056B2 (fr) |
BR (1) | BR0111733A (fr) |
CA (1) | CA2410303C (fr) |
DE (1) | DE60113533T2 (fr) |
EC (1) | ECSP024383A (fr) |
ES (1) | ES2248346T3 (fr) |
HK (1) | HK1057539A1 (fr) |
HR (1) | HRP20020963A2 (fr) |
HU (1) | HUP0300896A3 (fr) |
IL (1) | IL153166A0 (fr) |
JO (1) | JO2234B1 (fr) |
MA (1) | MA26913A1 (fr) |
MX (1) | MXPA02012253A (fr) |
NO (1) | NO20025823L (fr) |
NZ (1) | NZ522587A (fr) |
PE (1) | PE20020064A1 (fr) |
PL (1) | PL359811A1 (fr) |
RU (1) | RU2245871C2 (fr) |
UY (1) | UY26769A1 (fr) |
WO (1) | WO2001096285A1 (fr) |
YU (1) | YU90802A (fr) |
ZA (1) | ZA200209415B (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9916575D0 (en) * | 1999-07-15 | 1999-09-15 | Cambridge Combinatorial Ltd | Solid phase nitrile synthesis |
WO2002069901A2 (fr) * | 2001-03-02 | 2002-09-12 | Merck Frosst Canada & Co. | Inhibiteurs de cathepsines de la cysteine protease |
MXPA04001977A (es) * | 2001-09-13 | 2004-06-07 | Hoffmann La Roche | Antagonistas v de receptor ccr-3. |
US6759428B2 (en) * | 2001-12-04 | 2004-07-06 | Roche Palo Alto Llc | Indole nitriles |
RU2004120784A (ru) * | 2001-12-04 | 2005-08-10 | Ф.Хоффманн-Ля Рош Аг (Ch) | Замещенные 2-аминоциклоалканкарбоксамиды и их применение в качестве ингибиторов цистеиновой протеазы |
WO2004037181A2 (fr) | 2002-10-23 | 2004-05-06 | Bristol-Myers Squibb Company | Inhibiteurs de dipeptidyl peptidase iv a base de glycinenitrile et procedes correspondants |
RU2005141533A (ru) * | 2003-06-02 | 2006-08-10 | Ф.Хоффманн-Ля Рош Аг (Ch) | Бензамиднитрильные производные |
WO2005000793A1 (fr) * | 2003-06-26 | 2005-01-06 | Taisho Pharmaceutical Co., Ltd. | Derive d'acide cycloalkylcarboxylique substitue en position 2 |
EP1644326B1 (fr) * | 2003-06-30 | 2016-11-02 | Merck Canada Inc. | Inhibiteurs de la cathepsine cysteine protease |
EP1841730A4 (fr) * | 2005-01-19 | 2010-10-27 | Merck Frosst Canada Ltd | Inhibiteurs de la cathepsine k et atherosclerose |
WO2007003056A1 (fr) * | 2005-07-06 | 2007-01-11 | Merck Frosst Canada Ltd. | Inhibiteurs de cystéine protéases de type cathepsine |
EP2240491B1 (fr) | 2008-01-09 | 2015-07-15 | Amura Therapeutics Limited | DÉRIVÉS DE TÉTRAHYDROFURO(2,3-b)PYRROL-3-ONE COMME INHIBITEURS DE CYSTÉINE PROTÉINASES |
US7893099B2 (en) * | 2009-06-11 | 2011-02-22 | Hoffman-La Roche Inc. | Cyclopentane derivatives |
JP6021910B2 (ja) | 2011-07-26 | 2016-11-09 | サノフイ | 3−ヘテロアロイルアミノ−プロピオン酸誘導体及び医薬としてのそれらの使用 |
CN103086923B (zh) * | 2013-01-21 | 2014-04-23 | 吉林大学 | 肼腈类组织蛋白酶k抑制剂及其在治疗骨质疏松症方面的应用 |
JP6454335B2 (ja) * | 2013-10-08 | 2019-01-16 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | カテプシンシステインプロテアーゼ阻害剤 |
NO2699580T3 (fr) | 2014-01-24 | 2018-02-24 | ||
CN105837479B (zh) * | 2016-04-05 | 2017-10-27 | 吉林大学 | 肼腈类组织蛋白酶k抑制剂及其在制备治疗骨关节炎药物中的应用 |
CN113045491A (zh) * | 2019-12-26 | 2021-06-29 | 罗欣药业(上海)有限公司 | 一种仑伐替尼及中间体的制备方法 |
IL300855A (en) | 2020-08-26 | 2023-04-01 | Haisco Pharmaceuticals Pte Ltd | A nitrile derivative acting as an inhibitor of DIPEPTIDYL PEPTIDASE 1 and its use |
AU2021391452A1 (en) | 2020-12-04 | 2023-06-29 | Reistone Biopharma Company Limited | Small molecule inhibitor of cathepsin c and medicinal use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU177576B (en) | 1975-06-02 | 1981-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds |
IT1283467B1 (it) | 1996-07-19 | 1998-04-21 | Menarini Farma Ind | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni |
EP1024134A4 (fr) * | 1997-10-09 | 2003-05-14 | Ono Pharmaceutical Co | Derives d'acide aminobutanoique |
TR200001189T2 (tr) | 1997-11-05 | 2000-09-21 | Novartis Ag. | Dipeptid nitriller. |
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2001
- 2001-06-01 US US09/872,927 patent/US6462076B2/en not_active Expired - Fee Related
- 2001-06-07 JO JO200188A patent/JO2234B1/en active
- 2001-06-08 NZ NZ522587A patent/NZ522587A/en unknown
- 2001-06-08 KR KR1020027017073A patent/KR20030029057A/ko active IP Right Grant
- 2001-06-08 YU YU90802A patent/YU90802A/sh unknown
- 2001-06-08 EP EP01943489A patent/EP1294679B1/fr not_active Expired - Lifetime
- 2001-06-08 JP JP2002510429A patent/JP3872427B2/ja not_active Expired - Fee Related
- 2001-06-08 DE DE60113533T patent/DE60113533T2/de not_active Expired - Fee Related
- 2001-06-08 AU AU2001266056A patent/AU2001266056B2/en not_active Ceased
- 2001-06-08 BR BR0111733-5A patent/BR0111733A/pt not_active IP Right Cessation
- 2001-06-08 PL PL35981101A patent/PL359811A1/xx not_active Application Discontinuation
- 2001-06-08 CA CA002410303A patent/CA2410303C/fr not_active Expired - Fee Related
- 2001-06-08 MX MXPA02012253A patent/MXPA02012253A/es active IP Right Grant
- 2001-06-08 AT AT01943489T patent/ATE304997T1/de not_active IP Right Cessation
- 2001-06-08 AU AU6605601A patent/AU6605601A/xx active Pending
- 2001-06-08 IL IL15316601A patent/IL153166A0/xx unknown
- 2001-06-08 HU HU0300896A patent/HUP0300896A3/hu unknown
- 2001-06-08 ES ES01943489T patent/ES2248346T3/es not_active Expired - Lifetime
- 2001-06-08 CN CNB018110819A patent/CN1324006C/zh not_active Expired - Fee Related
- 2001-06-08 PE PE2001000541A patent/PE20020064A1/es not_active Application Discontinuation
- 2001-06-08 RU RU2002135634/04A patent/RU2245871C2/ru not_active IP Right Cessation
- 2001-06-08 WO PCT/EP2001/006541 patent/WO2001096285A1/fr active IP Right Grant
- 2001-06-12 AR ARP010102783A patent/AR031594A1/es not_active Application Discontinuation
- 2001-06-13 UY UY26769A patent/UY26769A1/es not_active Application Discontinuation
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2002
- 2002-11-19 ZA ZA200209415A patent/ZA200209415B/en unknown
- 2002-12-04 NO NO20025823A patent/NO20025823L/no not_active Application Discontinuation
- 2002-12-05 HR HR20020963A patent/HRP20020963A2/xx not_active Application Discontinuation
- 2002-12-13 EC EC2002004383A patent/ECSP024383A/es unknown
- 2002-12-13 MA MA26950A patent/MA26913A1/fr unknown
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2004
- 2004-01-21 HK HK04100483A patent/HK1057539A1/xx not_active IP Right Cessation
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