MA26057A1 - Appareil et procédé de perçage de peau par microdents - Google Patents

Appareil et procédé de perçage de peau par microdents

Info

Publication number
MA26057A1
MA26057A1 MA27151A MA27151A MA26057A1 MA 26057 A1 MA26057 A1 MA 26057A1 MA 27151 A MA27151 A MA 27151A MA 27151 A MA27151 A MA 27151A MA 26057 A1 MA26057 A1 MA 26057A1
Authority
MA
Morocco
Prior art keywords
impact
microprotrusion member
stratum corneum
skin
microdents
Prior art date
Application number
MA27151A
Other languages
English (en)
Inventor
Michel J N Cormier
Peter E Daddona
Richard L Keenan
Weiqi Lin
James A Matriano
Ahmad P Samiee
Joseph C Trautman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22906027&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA26057(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of MA26057A1 publication Critical patent/MA26057A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150801—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142—Devices intended for single use, i.e. disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Manufacturing & Machinery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Perforating, Stamping-Out Or Severing By Means Other Than Cutting (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Massaging Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
MA27151A 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents MA26057A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24030700P 2000-10-13 2000-10-13

Publications (1)

Publication Number Publication Date
MA26057A1 true MA26057A1 (fr) 2004-04-01

Family

ID=22906027

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27151A MA26057A1 (fr) 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents

Country Status (22)

Country Link
US (2) US7131960B2 (fr)
EP (1) EP1341453B1 (fr)
JP (1) JP4659332B2 (fr)
KR (1) KR20030068136A (fr)
CN (1) CN1250171C (fr)
AT (1) ATE428357T1 (fr)
AU (2) AU9682801A (fr)
BR (1) BR0114629A (fr)
CA (1) CA2425315C (fr)
CZ (1) CZ20031037A3 (fr)
DE (1) DE60138411D1 (fr)
ES (1) ES2324461T3 (fr)
HU (1) HUP0303558A2 (fr)
IL (1) IL155374A0 (fr)
MA (1) MA26057A1 (fr)
MX (1) MXPA03003299A (fr)
NO (1) NO20031681L (fr)
NZ (1) NZ525294A (fr)
PL (1) PL360998A1 (fr)
RU (1) RU2275871C2 (fr)
WO (1) WO2002030301A1 (fr)
ZA (1) ZA200303633B (fr)

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2195151T3 (es) * 1996-06-18 2003-12-01 Alza Corp Dispositivo de mejora de aporte o de muestreo de agentes transdermicos.
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
IL155389A0 (en) * 2000-10-13 2003-11-23 Alza Corportion Microprotrusion member retainer for impact applicator
EP1341453B1 (fr) * 2000-10-13 2009-04-15 Alza Corporation Dispositif et procede permettant la perforation de la peau au moyen de microprotuberances
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
IL155583A0 (en) 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
BR0209046A (pt) * 2001-04-20 2004-11-09 Alza Corp Disposição de microprojeção que possui um agente benéfico contendo revestimento
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
ES2297056T3 (es) 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US20040062813A1 (en) * 2002-06-28 2004-04-01 Cormier Michel J. N. Transdermal drug delivery devices having coated microprotrusions
MXPA05000597A (es) * 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
AU2003275301A1 (en) * 2002-09-30 2004-04-23 Alza Corporation Drug delivery device having coated microprojections incorporating vasoconstrictors
WO2004044557A2 (fr) 2002-11-12 2004-05-27 Argose, Inc. Mesure non invasive d'analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
US7087063B2 (en) * 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
CN1842320B (zh) * 2003-06-30 2013-06-19 阿尔扎公司 含有不挥发性平衡离子的用于经涂覆的微突出物的制剂
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
UY28398A1 (es) * 2003-07-02 2004-11-08 Alza Corp Método y parche de inmunización por disposición de microproyección
US20050031676A1 (en) * 2003-08-04 2005-02-10 Wong Patrick S.L. Method and device for enhancing transdermal agent flux
AU2004285484A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
WO2005041871A2 (fr) * 2003-10-24 2005-05-12 Alza Corporation Dispositif et procede d'amelioration de l'administration transdermique de medicament
WO2005044985A2 (fr) * 2003-10-28 2005-05-19 Alza Corporation Administration de conjugues polymeres de peptides et de proteines therapeutiques par le biais de microprotuberances revetues
CA2543154A1 (fr) * 2003-10-28 2005-05-19 Alza Corporation Procede et appareil de reduction de l'incidence du tabagisme
EP1680154B1 (fr) * 2003-10-31 2012-01-04 ALZA Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
EP1706171A1 (fr) * 2003-12-29 2006-10-04 3M Innovative Properties Company Dispositifs medicaux et kits comprenant ces dispositifs
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
SG136133A1 (en) 2004-03-08 2007-10-29 Ichor Medical Systems Inc Ca U Improved apparatus for electrically mediated delivery of therapeutic agents
AU2005228145B2 (en) 2004-03-24 2011-03-03 Corium Pharma Solutions, Inc. Transdermal delivery device
EP1735469A2 (fr) * 2004-04-13 2006-12-27 ALZA Corporation Appareil et procede d'administration transdermique de multiples vaccins
CA2566032A1 (fr) 2004-05-13 2005-12-01 Alza Corporation Appareil et procede pour la delivrance transdermique d'agents a base d'hormone parathyroide
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
CA2579509A1 (fr) * 2004-09-08 2006-03-16 Alza Corporation Reseau de protuberances microscopiques possedant une adherence a la peau et une conformite ameliorees
BRPI0517749A (pt) 2004-11-18 2008-10-21 3M Innovative Properties Co dispositivo de aplicação para aplicar um dispositivo de micro-agulha a uma superfìcie de pele, e, método para usar um dispositivo de aplicação
CN101060882B (zh) 2004-11-18 2010-06-16 3M创新有限公司 微针阵列施放器和保持器
EP1853231A2 (fr) * 2005-02-16 2007-11-14 Alza Corporation Dispositif et procede d'administration transdermique d'agents a base d'epoetine s
EP1869414A4 (fr) 2005-03-29 2010-07-28 Arkal Medical Inc Dispositifs, systemes, procedes et outils pour la surveillance continue du glucose
WO2006108185A1 (fr) 2005-04-07 2006-10-12 3M Innovative Properties Company Systeme et procede de captage de retroaction d’un outil
AU2006252342A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2007002523A2 (fr) 2005-06-24 2007-01-04 3M Innovative Properties Company Timbre repliable et son procede d'application
CA2613111C (fr) 2005-06-27 2015-05-26 3M Innovative Properties Company Dispositif applicateur de matrice de micro-aiguilles et procede d'application d'une telle matrice
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CN101267896A (zh) * 2005-09-12 2008-09-17 阿尔扎公司 可涂覆的透皮给药微突起组合件
EP1957145A4 (fr) * 2005-11-30 2011-03-23 3M Innovative Properties Co Reseaux de microaiguilles et leurs methodes d'utilisation
JP4963849B2 (ja) * 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
CN101466393A (zh) * 2006-03-15 2009-06-24 阿尔扎公司 用于经皮递送甲状旁腺激素药剂以治疗骨质减少的方法
WO2007124411A1 (fr) * 2006-04-20 2007-11-01 3M Innovative Properties Company Dispositif de pose d'une barrette de microaiguilles
WO2007127815A2 (fr) * 2006-04-25 2007-11-08 Alza Corporation Application d'un réseau de microprotubérances muni d'éléments de microprotubérances multicouches pour charge de médicament élevée
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (fr) 2007-04-16 2020-08-12 Corium, Inc. Réseaux de micro-aiguilles coulées dans un solvant contenant un actif
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
EP2211918B1 (fr) * 2007-10-29 2017-10-18 Syneron Medical Ltd. Séchage vertical de timbres transdermiques
WO2009129349A2 (fr) * 2008-04-16 2009-10-22 Kim Stanley I Dispositif auto-piqueur jetable à usage unique et procédés
RU2494769C2 (ru) * 2008-11-18 2013-10-10 3М Инновейтив Пропертиз Компани Массив полых микроигл и способ его использования
WO2010101620A2 (fr) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systèmes et procédés permettant de créer et d'utiliser des bulles de succion ou d'autres régions groupées de fluide dans la peau
WO2012018486A2 (fr) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Distribution et/ou réception rapide de fluides
US9119578B2 (en) 2011-04-29 2015-09-01 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
US10010706B2 (en) 2009-07-31 2018-07-03 3M Innovative Properties Company Hollow microneedle arrays
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
WO2011105496A1 (fr) * 2010-02-24 2011-09-01 久光製薬株式会社 Dispositif à micro-aiguilles
WO2011135530A2 (fr) * 2010-04-28 2011-11-03 Kimberly-Clark Worldwide, Inc. Dispositif pour administrer un médicament contre l'arthrite rhumatoïde
WO2011135531A2 (fr) * 2010-04-28 2011-11-03 Kimberly-Clark Worldwide, Inc. DISPOSITIFS MÉDICAUX POUR L'ADMINISTRATION D'ARNsi
GB201007207D0 (en) 2010-04-29 2010-06-16 Univ Cork Method
KR101808635B1 (ko) 2010-05-04 2017-12-13 코리움 인터네셔널, 인크. 미세 바늘을 위한 어플리케이터
EP2566501B1 (fr) * 2010-05-04 2019-03-13 Corium International, Inc. Méthode et dispositif permettant l'administration transdermique d'hormone parathyroïdienne au moyen d'un réseau de microprojections
KR101759370B1 (ko) 2010-05-28 2017-07-18 히사미쓰 세이야꾸 가부시키가이샤 미소 돌기가 형성된 어레이
WO2011148994A1 (fr) 2010-05-28 2011-12-01 久光製薬株式会社 Dispositif pourvu d'une matrice dotée de fines saillies
JP5562138B2 (ja) 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
EP2399635A1 (fr) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
US8257379B2 (en) * 2010-07-29 2012-09-04 Kyphon Sarl Tissue structure perforation system and method
WO2012021801A2 (fr) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systèmes et procédés adaptés pour surveiller des sujets
US20130226098A1 (en) * 2010-10-07 2013-08-29 Hisamitsu Pharmaceutical Co., Inc. Applicator
DE202010013095U1 (de) 2010-12-10 2011-02-17 Mt Derm Gmbh Vorrichtung zum wiederholten Aufstechen von Haut und Stechmodul
EP2489386A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489388A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489381A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489380A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Dispositif d'injection
RU2612959C2 (ru) 2011-02-18 2017-03-14 АСАНА БАЙОСАЙЕНСИЗ, ЭлЭлСи Аминоиндановые соединения и их применение при лечении боли
EP2489382A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489385A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489390A1 (fr) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489389A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489384A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489387A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
KR20120119250A (ko) * 2011-04-21 2012-10-31 (주)마이티시스템 단턱이 형성된 미세바늘
KR102013466B1 (ko) 2011-04-29 2019-08-22 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
WO2012149155A1 (fr) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systèmes et procédés pour collecter un fluide d'un sujet
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
KR102022574B1 (ko) 2011-10-12 2019-09-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 통합된 마이크로니들 어레이 전달 시스템
DK2771320T3 (en) 2011-10-24 2016-10-03 Endo Pharmaceuticals Inc Cyclohexylamines
USD733290S1 (en) 2012-01-27 2015-06-30 3M Innovative Properties Company Microneedle applicator
KR102064628B1 (ko) 2012-04-05 2020-01-08 히사미쓰 세이야꾸 가부시키가이샤 천자 장치 및 그 제조 방법
EP4112112A1 (fr) * 2012-05-01 2023-01-04 University of Pittsburgh - Of the Commonwealth System of Higher Education Réseaux de micro-aiguilles à extrémité chargée pour l'insertion transdermique
JP6009302B2 (ja) * 2012-09-27 2016-10-19 シスメックス株式会社 微細孔形成装置、微細針チップおよびチップホルダ
CN105073102B (zh) 2012-10-01 2018-06-19 香港科技大学 透皮贴装置
WO2014097837A1 (fr) 2012-12-21 2014-06-26 久光製薬株式会社 Applicateur
CA2896188C (fr) 2012-12-21 2021-02-23 Corium International, Inc. Micro-reseau pour la distribution d'un agent therapeutique et ses procedes d'utilisation
KR102244475B1 (ko) * 2013-01-08 2021-04-23 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 장치를 피부에 적용하기 위한 어플리케이터
ES2921481T3 (es) 2013-03-12 2022-08-26 Corium Inc Aplicadores para microproyecciones
AU2014233695A1 (en) 2013-03-15 2015-10-01 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
EP2968751B1 (fr) 2013-03-15 2022-11-30 Corium, Inc. Applicateurs de microprojection d'impacts multiples
WO2014144973A1 (fr) 2013-03-15 2014-09-18 Corium International, Inc. Micro-réseau pour administrer un agent thérapeutique, procédés d'utilisation et procédés de fabrication
WO2015017561A1 (fr) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Applicateur extra-plat de tampon de micro-aiguilles
WO2015040697A1 (fr) 2013-09-18 2015-03-26 コスメディ製薬株式会社 Dispositif d'application de timbre de micro-aiguille et organe de retenue de timbre
JP6215343B2 (ja) 2013-11-05 2017-10-18 久光製薬株式会社 アプリケータ
CA2933811C (fr) 2013-12-16 2021-02-09 Asana Biosciences, Llc Composes de p2x3 et/ou p2x2/3 et procedes
CN103654969B (zh) * 2013-12-24 2015-12-30 湖州美奇医疗器械有限公司 一种医疗助针器
WO2016036866A1 (fr) 2014-09-04 2016-03-10 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
US10137289B2 (en) * 2014-12-20 2018-11-27 Esthetic Education LLC Microneedle cartridge and nosecone assembly
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) * 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
KR102135518B1 (ko) 2015-09-02 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
EP3416618A1 (fr) 2016-02-19 2018-12-26 ZP Opco, Inc. Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines
KR102377747B1 (ko) 2016-03-16 2022-03-23 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 패치 케이스
IL296595A (en) 2016-03-28 2022-11-01 Ichor Medical Systems Inc Method and device for administering medical substances
WO2018064135A1 (fr) 2016-09-30 2018-04-05 Asana Biosciences, Llc Composés p2x3 et/ou p2x2/3 et méthodes associées
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
US11660264B2 (en) * 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
CA3073442C (fr) 2017-08-23 2024-02-06 Zosano Pharma Corporation Procede d'obtention rapide de concentrations therapeutiques de zolmitriptan pour le traitement de migraines et de cephalees de horton
US11458289B2 (en) 2017-10-17 2022-10-04 Kindeva Drug Delivery L.P. Applicator for applying a microneedle array to skin
CN111629772A (zh) 2018-01-24 2020-09-04 考司美德制药株式会社 微针用张紧器具
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ２

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) * 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6048337A (en) * 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
ATE171629T1 (de) 1994-08-18 1998-10-15 Nmt Group Plc Vorrichtungen zum zurückziehen von nadeln
JPH10510175A (ja) * 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
WO1996037256A1 (fr) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Timbre micromecanique pour ameliorer l'administration de composes a travers la peau
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
ES2195151T3 (es) 1996-06-18 2003-12-01 Alza Corp Dispositivo de mejora de aporte o de muestreo de agentes transdermicos.
US6183434B1 (en) 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
ATE231015T1 (de) 1996-09-17 2003-02-15 Deka Products Lp System zur medikamentenabgabe durch transport
CN1133472C (zh) * 1996-12-20 2004-01-07 阿尔萨公司 增加经皮样剂流量的装置
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
DK1037686T3 (da) * 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP1037687B8 (fr) 1997-12-11 2008-10-22 Alza Corporation Dispositif renfor ant le flux d'agents transdermiques
CA2330207C (fr) 1998-06-10 2005-08-30 Georgia Tech Research Corporation Dispositifs a microaiguilles et procedes de fabrication et d'utilisation correspondants
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
CN100402105C (zh) * 1999-06-08 2008-07-16 奥尔蒂治疗学公司 采用薄膜组织界面装置在生物膜中制作微孔的设备及方法
US6364889B1 (en) * 1999-11-17 2002-04-02 Bayer Corporation Electronic lancing device
WO2001043643A1 (fr) * 1999-12-16 2001-06-21 Alza Corporation Dispositif destine a augmenter le flux transdermique de substances echantillonnees
IL155389A0 (en) * 2000-10-13 2003-11-23 Alza Corportion Microprotrusion member retainer for impact applicator
WO2002030281A1 (fr) * 2000-10-13 2002-04-18 Alza Corporation Applicateur a reseau de microlames produisant un impact
EP1341453B1 (fr) * 2000-10-13 2009-04-15 Alza Corporation Dispositif et procede permettant la perforation de la peau au moyen de microprotuberances
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
IL155583A0 (en) * 2000-10-26 2003-11-23 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
BR0209046A (pt) * 2001-04-20 2004-11-09 Alza Corp Disposição de microprojeção que possui um agente benéfico contendo revestimento
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
ES2297056T3 (es) * 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
US20040062813A1 (en) * 2002-06-28 2004-04-01 Cormier Michel J. N. Transdermal drug delivery devices having coated microprotrusions
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CN1842320B (zh) * 2003-06-30 2013-06-19 阿尔扎公司 含有不挥发性平衡离子的用于经涂覆的微突出物的制剂
WO2005044985A2 (fr) * 2003-10-28 2005-05-19 Alza Corporation Administration de conjugues polymeres de peptides et de proteines therapeutiques par le biais de microprotuberances revetues
EP1680154B1 (fr) * 2003-10-31 2012-01-04 ALZA Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
WO2005051456A2 (fr) * 2003-11-13 2005-06-09 Alza Corporation Composition et appareil d'administration transdermique
CA2566032A1 (fr) * 2004-05-13 2005-12-01 Alza Corporation Appareil et procede pour la delivrance transdermique d'agents a base d'hormone parathyroide

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US20020123675A1 (en) 2002-09-05
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US20050234401A1 (en) 2005-10-20
EP1341453A1 (fr) 2003-09-10
IL155374A0 (en) 2003-11-23
DE60138411D1 (de) 2009-05-28
CZ20031037A3 (cs) 2003-10-15
RU2275871C2 (ru) 2006-05-10
JP2004510535A (ja) 2004-04-08
CA2425315A1 (fr) 2002-04-18
NO20031681D0 (no) 2003-04-11
CN1479590A (zh) 2004-03-03
NO20031681L (no) 2003-06-13
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ZA200303633B (en) 2004-05-12
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CN1250171C (zh) 2006-04-12
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US7798987B2 (en) 2010-09-21
ES2324461T3 (es) 2009-08-07
CA2425315C (fr) 2010-01-12
NZ525294A (en) 2005-02-25
KR20030068136A (ko) 2003-08-19
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JP4659332B2 (ja) 2011-03-30
BR0114629A (pt) 2004-01-20

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