LUC00133I2 - - Google Patents

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Publication number
LUC00133I2
LUC00133I2 LU00133C LUC00133C LUC00133I2 LU C00133 I2 LUC00133 I2 LU C00133I2 LU 00133 C LU00133 C LU 00133C LU C00133 C LUC00133 C LU C00133C LU C00133 I2 LUC00133 I2 LU C00133I2
Authority
LU
Luxembourg
Application number
LU00133C
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00133(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of LUC00133I1 publication Critical patent/LUC00133I1/fr
Publication of LUC00133I2 publication Critical patent/LUC00133I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU00133C 2007-05-25 2019-10-14 LUC00133I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
LU2008006661 2008-05-23

Publications (2)

Publication Number Publication Date
LUC00133I1 LUC00133I1 (fr) 2019-10-16
LUC00133I2 true LUC00133I2 (fr) 2020-07-16

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00133C LUC00133I2 (fr) 2007-05-25 2019-10-14

Country Status (30)

Country Link
US (1) US7534595B2 (fr)
EP (2) EP2657335A1 (fr)
JP (1) JP5670183B2 (fr)
KR (2) KR101603796B1 (fr)
CN (1) CN101842482B (fr)
AR (2) AR066716A1 (fr)
AU (1) AU2008263190B2 (fr)
BR (1) BRPI0811267B8 (fr)
CA (1) CA2687450C (fr)
CL (1) CL2008001497A1 (fr)
CY (2) CY1116894T1 (fr)
DK (1) DK2152868T3 (fr)
EA (1) EA018443B1 (fr)
ES (1) ES2551315T3 (fr)
HK (1) HK1135141A1 (fr)
HR (1) HRP20151268T1 (fr)
HU (2) HUE025784T2 (fr)
IL (1) IL202132A (fr)
LT (1) LTC2152868I2 (fr)
LU (1) LUC00133I2 (fr)
MX (1) MX2009012453A (fr)
MY (1) MY151413A (fr)
NL (1) NL301011I2 (fr)
NO (1) NO2019037I1 (fr)
PE (1) PE20090315A1 (fr)
PL (1) PL2152868T3 (fr)
PT (1) PT2152868E (fr)
SI (1) SI2152868T1 (fr)
TW (1) TWI418633B (fr)
WO (1) WO2008153776A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7537923B2 (en) * 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
WO2010014225A2 (fr) 2008-07-30 2010-02-04 Biomarin Pharmaceutical Inc. Dosages permettant la détection de la phénylalanine ammoniac-lyase et des anticorps contre la phénylalanine ammoniac-lyase
PT3025728T (pt) * 2010-02-04 2018-11-05 Biomarin Pharm Inc Método para purificar variantes procarióticas de fenilalanina amónia-liase
AU2013295621A1 (en) * 2012-07-27 2015-03-12 University Of North Texas Genetically modified probiotic for the treatment of phenylketonuria (PKU) disease
DK2986722T3 (da) 2013-04-18 2019-05-13 Codexis Inc Manipulerede phenylalaninammoniak-lyasepolypeptider
CA2930665A1 (fr) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Complexes membrane synthetique- recepteur
CN106456744A (zh) 2014-04-01 2017-02-22 鲁比厄斯治疗法股份有限公司 用于免疫调节的方法和组合物
EP3928787A1 (fr) * 2014-04-16 2021-12-29 Codexis, Inc. Tyrosine ammoniac-lyase génétiquement modifiée
KR20220123342A (ko) 2014-12-22 2022-09-06 코덱시스, 인코포레이티드 인간 알파-갈락토시다제 변이체
TWI797060B (zh) 2015-08-04 2023-04-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
SG11201811603WA (en) 2016-07-26 2019-02-27 Biomarin Pharm Inc Novel adeno-associated virus capsid proteins
CN109844127B (zh) * 2016-08-30 2023-09-19 三菱化学株式会社 突变型酶的制造方法及突变型醇酰基转移酶
CN106497905A (zh) * 2016-12-14 2017-03-15 江南大学 一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
CN110573175A (zh) 2017-02-13 2019-12-13 科德克希思公司 工程化苯丙氨酸氨裂合酶多肽
CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
US11739345B2 (en) 2018-05-09 2023-08-29 Biomarin Pharmaceutical Inc. Methods of treating phenylketonuria
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
CA3102968A1 (fr) * 2018-06-12 2019-12-19 Codexis, Inc. Tyrosine ammonia-lyase modifiee
WO2020013951A1 (fr) * 2018-07-12 2020-01-16 Codexis, Inc. Polypeptides de phénylalanine ammonia-lyase modifiés
WO2020123286A1 (fr) 2018-12-14 2020-06-18 Codexis, Inc. Tyrosine ammonia-lyase modifiée
CA3123598A1 (fr) 2018-12-20 2020-06-25 Codexis, Inc. Variants d'alpha-galactosidase humaine
CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
US11987823B2 (en) 2019-08-30 2024-05-21 Societe Des Produits Nestle S.A. Engineered lipase variants
IL294082A (en) 2019-12-20 2022-08-01 Codexis Inc Transgenic variants of acid alpha-glycosidase
AR122409A1 (es) 2020-04-03 2022-09-07 Biomarin Pharm Inc Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
US11959108B2 (en) 2020-08-28 2024-04-16 Codexis, Inc. Engineered protease variants
BR112023003643A2 (pt) 2020-08-28 2023-03-28 Codexis Inc Amilase recombinante, composição, sequência de polinucleotídeo recombinante, vetor de expressão, célula hospedeira, métodos para produzir uma amilase recombinante e para tratar e/ou prevenir os sintomas de insuficiência pancreática, composição farmacêutica para o tratamento de insuficiência pancreática, e, uso
WO2022245924A1 (fr) * 2021-05-19 2022-11-24 Biomarin Pharmaceutical Inc. Compositions de phénylalanine ammonia-lyase procaryotique et méthodes de traitement de sujets adolescents
WO2023044381A1 (fr) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions et procédés de traitement de la phénylcétonurie
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN116478975B (zh) * 2023-06-16 2023-09-01 苏州优信合生技术有限公司 高活性苯丙氨酸解氨酶突变体及其表达菌株

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US4252822A (en) * 1979-12-26 1981-02-24 Children's Hospital Medical Center Method for treating phenylketonuria
US4562151A (en) * 1983-09-06 1985-12-31 Monsanto Company Stabilization of L-phenylalanine ammonia-lyase enzyme
US5206344A (en) * 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US5166322A (en) 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof
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ATE545703T1 (de) * 2000-07-25 2012-03-15 Immunomedics Inc Multivalentes zielbindendes protein
AU2001294774A1 (en) * 2000-09-26 2002-04-08 The Regents Of The University Of California Characterization of phenylalanine ammonia-lyase (pal) gene in wounded lettuce
WO2002038609A2 (fr) * 2000-11-10 2002-05-16 Proteopharma Aps Analogues d'apolipoproteine
IL162811A0 (en) 2002-02-26 2005-11-20 Du Pont Method for the recombination of genetic elements
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US20080124275A1 (en) 2002-11-14 2008-05-29 The Scripps Research Institute Crystalline Form of Fatty Acid Amide Hydrolase (Faah)
KR20060022261A (ko) * 2003-06-11 2006-03-09 와이어쓰 혈소판 당단백질 ｉｂ 알파 변이체 융합 폴리펩티드 및이의 사용 방법
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US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US20090011400A1 (en) 2006-12-01 2009-01-08 The Salk Institute for Biological Studies and The Regents of the University of California Substrate switched ammonia lyases and mutases
US7537923B2 (en) * 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof

Also Published As

Publication number Publication date
LTPA2019517I1 (lt) 2019-10-25
DK2152868T3 (en) 2015-11-16
AR066716A1 (es) 2009-09-09
MX2009012453A (es) 2010-01-25
US20080008695A1 (en) 2008-01-10
PL2152868T3 (pl) 2016-01-29
CY2019039I2 (el) 2020-05-29
NL301011I2 (nl) 2020-05-13
BRPI0811267B8 (pt) 2021-05-25
BRPI0811267A2 (pt) 2014-10-07
EA200970980A1 (ru) 2010-04-30
KR20150038753A (ko) 2015-04-08
NO2019037I1 (no) 2019-10-16
CL2008001497A1 (es) 2009-01-09
HUS1900049I1 (hu) 2019-11-28
TWI418633B (zh) 2013-12-11
EP2152868B1 (fr) 2015-09-02
CY1116894T1 (el) 2017-04-05
CY2019039I1 (el) 2020-05-29
JP2010529835A (ja) 2010-09-02
AR110834A2 (es) 2019-05-08
US7534595B2 (en) 2009-05-19
LTC2152868I2 (lt) 2020-09-25
IL202132A (en) 2017-06-29
EP2657335A1 (fr) 2013-10-30
SI2152868T1 (sl) 2015-12-31
JP5670183B2 (ja) 2015-02-18
LUC00133I1 (fr) 2019-10-16
WO2008153776A8 (fr) 2009-07-30
CA2687450C (fr) 2019-03-26
WO2008153776A1 (fr) 2008-12-18
IL202132A0 (en) 2010-06-16
KR20100024437A (ko) 2010-03-05
TW200902052A (en) 2009-01-16
HK1135141A1 (zh) 2010-05-28
HUE025784T2 (en) 2016-05-30
AU2008263190B2 (en) 2014-04-17
CN101842482A (zh) 2010-09-22
PE20090315A1 (es) 2009-03-19
HRP20151268T1 (hr) 2015-12-18
EA018443B1 (ru) 2013-08-30
PT2152868E (pt) 2015-11-13
NL301011I1 (nl) 2019-10-16
BRPI0811267B1 (pt) 2020-11-10
AU2008263190A1 (en) 2008-12-18
EP2152868A1 (fr) 2010-02-17
MY151413A (en) 2014-05-30
KR101603796B1 (ko) 2016-03-17
CA2687450A1 (fr) 2008-12-18
ES2551315T3 (es) 2015-11-18
CN101842482B (zh) 2014-10-22

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