LT2489733T - Šoninės amiotrofinės sklerozės ir kitų nugaros smegenų sutrikimų genų terapija - Google Patents
Šoninės amiotrofinės sklerozės ir kitų nugaros smegenų sutrikimų genų terapijaInfo
- Publication number
- LT2489733T LT2489733T LTEP12152550.5T LT12152550T LT2489733T LT 2489733 T LT2489733 T LT 2489733T LT 12152550 T LT12152550 T LT 12152550T LT 2489733 T LT2489733 T LT 2489733T
- Authority
- LT
- Lithuania
- Prior art keywords
- gene therapy
- spinal cord
- lateral sclerosis
- amyotrophic lateral
- cord disorders
- Prior art date
Links
- 208000029033 Spinal Cord disease Diseases 0.000 title 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 title 1
- 238000001415 gene therapy Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/864—Parvoviral vectors, e.g. parvovirus, densovirus
- C12N15/8645—Adeno-associated virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/025—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a parvovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81141906P | 2006-06-07 | 2006-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2489733T true LT2489733T (lt) | 2019-05-27 |
Family
ID=38832369
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP12152550.5T LT2489733T (lt) | 2006-06-07 | 2007-06-07 | Šoninės amiotrofinės sklerozės ir kitų nugaros smegenų sutrikimų genų terapija |
LTEP07795835.3T LT2029742T (lt) | 2006-06-07 | 2007-06-07 | Genų terapija, skirta amiotrofinei lateralinei sklerozei ir kitiems stuburo smegenų sutrikimams |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP07795835.3T LT2029742T (lt) | 2006-06-07 | 2007-06-07 | Genų terapija, skirta amiotrofinei lateralinei sklerozei ir kitiems stuburo smegenų sutrikimams |
Country Status (19)
Country | Link |
---|---|
US (4) | US9034836B2 (pt) |
EP (3) | EP2489733B1 (pt) |
JP (6) | JP2009539847A (pt) |
CN (1) | CN101460621B (pt) |
AR (2) | AR061282A1 (pt) |
BR (1) | BRPI0711965A2 (pt) |
CA (2) | CA3139726A1 (pt) |
CY (1) | CY1118555T1 (pt) |
ES (2) | ES2596885T3 (pt) |
HU (2) | HUE044182T2 (pt) |
IL (2) | IL195647A (pt) |
LT (2) | LT2489733T (pt) |
MX (4) | MX364444B (pt) |
PL (2) | PL2029742T3 (pt) |
PT (2) | PT2029742T (pt) |
RU (1) | RU2008152821A (pt) |
SI (2) | SI2489733T1 (pt) |
TR (1) | TR201906106T4 (pt) |
WO (1) | WO2007146046A2 (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3139726A1 (en) | 2006-06-07 | 2007-12-21 | Genzyme Corporation | Gene therapy for motor disorders |
WO2009089635A1 (en) * | 2008-01-16 | 2009-07-23 | Neurodyn, Inc. | Treating neurodegenerative diseases with progranulin (pgrn) |
WO2010048710A1 (en) | 2008-10-31 | 2010-05-06 | Neurodyn, Inc. | Neurotoxic sterol glycosides |
CN102459611B (zh) | 2009-05-02 | 2016-11-09 | 建新公司 | 神经退行性疾病的基因治疗 |
US20150352185A1 (en) * | 2010-11-16 | 2015-12-10 | Denis G. Kay | Method for increasing neprilysin expression and activity |
CN103083667A (zh) * | 2011-11-01 | 2013-05-08 | 北京清美联创干细胞科技有限公司 | 嗅鞘细胞增殖试剂的连续给药方案 |
WO2013112871A1 (en) | 2012-01-27 | 2013-08-01 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic il-13 polypeptides |
US9663564B2 (en) | 2013-03-15 | 2017-05-30 | The Regents Of The University Of California | Vectors and methods to treat ischemia |
US20140065110A1 (en) * | 2012-08-31 | 2014-03-06 | The Regents Of The University Of California | Genetically modified msc and therapeutic methods |
JP6262661B2 (ja) | 2012-10-24 | 2018-01-17 | 第一三共株式会社 | 筋萎縮性側索硬化症治療剤 |
JP6232547B2 (ja) * | 2012-11-28 | 2017-11-22 | 国立大学法人名古屋大学 | 聴覚障害又は小脳性運動失調症の予防・治療剤 |
KR20200060536A (ko) | 2013-05-01 | 2020-05-29 | 젠자임 코포레이션 | 척수성 근위축증을 치료하기 위한 조성물 및 방법 |
ES2859605T3 (es) | 2013-07-26 | 2021-10-04 | Univ Iowa Res Found | Procedimientos y composiciones para tratar enfermedades del cerebro |
KR101548989B1 (ko) | 2013-07-30 | 2015-09-01 | 광주과학기술원 | SirT1을 이용한 관절 질환의 예방 또는 치료용 물질의 스크리닝 방법 |
US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
DE102014207498A1 (de) * | 2014-04-17 | 2015-10-22 | Universitätsklinikum Hamburg-Eppendorf | Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark |
CN107106689A (zh) | 2014-11-05 | 2017-08-29 | 沃雅戈治疗公司 | 用于治疗帕金森病的aadc多核苷酸 |
US10214731B2 (en) * | 2015-05-28 | 2019-02-26 | Cornell University | Adeno-associated virus mediated delivery of C1E1 as a therapy for angioedema |
CL2015003024A1 (es) | 2015-10-09 | 2016-05-13 | Univ Chile | Método de tratamiento genético utilizando el virus aav-xbp1s/gfp, y su uso en la prevención y tratamiento de la esclerosis lateral amiotrofica. |
US10357543B2 (en) | 2015-11-16 | 2019-07-23 | Ohio State Innovation Foundation | Methods and compositions for treating disorders and diseases using Survival Motor Neuron (SMN) protein |
CA3016314A1 (en) * | 2016-03-02 | 2017-09-08 | Julianne REIDERS | Therapy for frontotemporal dementia |
JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
CA3053399A1 (en) | 2017-02-28 | 2018-09-07 | The Trustees Of The University Of Pennsylvania | Novel adeno-associated virus (aav) clade f vector and uses therefor |
JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
US11807849B2 (en) | 2017-10-03 | 2023-11-07 | Prevail Therapeutics, Inc. | Gene therapies for lysosomal disorders |
EP3692075A4 (en) | 2017-10-03 | 2022-02-09 | Prevail Therapeutics, Inc. | GENE THERAPIES FOR LYSOSOMAL DISEASES |
MX2020003965A (es) | 2017-10-03 | 2020-10-05 | Prevail Therapeutics Inc | Terapias genicas para los trastornos lisosomales. |
CN111405911A (zh) * | 2017-10-10 | 2020-07-10 | 梅迪塞纳医疗股份有限公司 | 用于治疗中枢神经***(cns)肿瘤的il-4融合制剂 |
RU2731514C2 (ru) * | 2018-12-21 | 2020-09-03 | Селл энд Джин Терапи Лтд | Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов SHH, CTNNB1, NOG, WNT7A для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-SHH, или Escherichia coli SCS110-AF/VTvaf17-CTNNB1, или Escherichia coli SCS110-AF/VTvaf17-NOG, или Escherichia coli SCS110-AF/VTvaf17-WNT7A, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора |
WO2020160458A1 (en) * | 2019-02-01 | 2020-08-06 | Avrobio, Inc. | Compositions and methods for treating neurocognitive disorders |
JP2022523766A (ja) * | 2019-02-22 | 2022-04-26 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | Grn関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス |
US11999974B2 (en) | 2019-04-10 | 2024-06-04 | Prevail Therapeutics, Inc. | Gene therapies for lysosomal disorders |
BR112021020421A2 (pt) * | 2019-04-12 | 2021-12-21 | Encoded Therapeutics Inc | Composições e métodos para administração de componentes terapêuticos |
US20220235373A1 (en) * | 2019-10-12 | 2022-07-28 | Shenzhen University | Agent that enables sirt7 gene expression and the use thereof |
BR112022012230A2 (pt) | 2019-12-23 | 2022-08-30 | Denali Therapeutics Inc | Variantes de progranulina |
CN115323002A (zh) * | 2022-07-28 | 2022-11-11 | 深圳先进技术研究院 | 一种基因递送***在从脑部逆行递送基因到脊髓神经元中的应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8303626D0 (sv) | 1983-06-23 | 1983-06-23 | Kabigen Ab | A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced |
US5672344A (en) | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
ATE304604T1 (de) | 1993-06-24 | 2005-09-15 | Frank L Graham | Adenovirus vektoren für gentherapie |
PT797676E (pt) | 1993-10-25 | 2006-05-31 | Canji Inc | Vector adenoviral recombinante e metodos de utilizacao |
DK0733103T3 (da) | 1993-11-09 | 2004-07-12 | Univ Johns Hopkins | Fremstilling af höje titre af rekombinante AAV vektorer |
US7252989B1 (en) | 1994-04-04 | 2007-08-07 | Board Of Regents, The University Of Texas System | Adenovirus supervector system |
ATE386131T1 (de) | 1994-04-13 | 2008-03-15 | Univ Rockefeller | Aav-vermittelte überbringung von dna in zellen des nervensystems |
US5882914A (en) | 1995-06-06 | 1999-03-16 | The Johns Hopkins University School Of Medicine | Nucleic acids encoding the hypoxia inducible factor-1 |
AU1525797A (en) | 1996-04-22 | 1997-11-12 | Medtronic, Inc. | Two-stage angled venous cannula |
US20040076613A1 (en) * | 2000-11-03 | 2004-04-22 | Nicholas Mazarakis | Vector system |
CA2311643C (en) | 1997-12-04 | 2009-04-07 | Genzyme Corporation | Compositions and methods for inducing gene expression |
US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
US6468524B1 (en) | 2000-03-22 | 2002-10-22 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | AAV4 vector and uses thereof |
US7037493B2 (en) * | 2000-05-01 | 2006-05-02 | Cornell Research Foundation, Inc. | Method of inducing neuronal production in the brain and spinal cord |
NZ522841A (en) * | 2000-06-01 | 2004-12-24 | Univ North Carolina | Surgically implantable matrix with a viral vector dried onto it for controlled release of recombinant parvovirus vectors |
DE60115070T2 (de) | 2000-09-18 | 2006-07-27 | Genzyme Corp., Cambridge | Expressionsvektoren mit hybriden ubiquitin-promotoren |
GB0103998D0 (en) * | 2001-02-19 | 2001-04-04 | King S College London | Method |
JP2002322068A (ja) | 2001-02-26 | 2002-11-08 | Japan Science & Technology Corp | 血管再生促進剤 |
EP1402043A1 (en) * | 2001-07-03 | 2004-03-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods of administering vectors to synaptically connected neurons |
AU2002364221B2 (en) | 2001-12-21 | 2008-07-10 | The Salk Institute For Biological Studies | Targeted retrograde gene delivery to motor neurons |
US7241444B2 (en) * | 2002-01-18 | 2007-07-10 | Pierre Fabre Medicament | Anti-IGF-IR antibodies and uses thereof |
US7576065B2 (en) * | 2002-02-15 | 2009-08-18 | Cornell Research Foundation, Inc. | Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein |
US20060246036A1 (en) * | 2002-09-06 | 2006-11-02 | The General Hospital Corporation | Delivery of therapeutics to the brain and spinal cord |
WO2006035741A1 (ja) * | 2004-09-29 | 2006-04-06 | Dainippon Sumitomo Pharma Co., Ltd. | Es細胞特異的発現遺伝子及びその利用 |
EP1878793B1 (en) | 2004-11-18 | 2011-08-24 | Tokyo Medical and Dental University | Novel protein and preventive/remedy for neurodegenerative disease such as polyglutamine disease using the same |
EP1879623B1 (en) * | 2005-05-02 | 2012-10-03 | Genzyme Corporation | Gene therapy for spinal cord disorders |
ES2887076T3 (es) | 2005-05-02 | 2021-12-21 | Genzyme Corp | Terapia génica para trastornos neurometabólicos |
CA3139726A1 (en) | 2006-06-07 | 2007-12-21 | Genzyme Corporation | Gene therapy for motor disorders |
LT2773354T (lt) | 2011-11-01 | 2019-08-12 | Resverlogix Corp. | Geriamosios greitai atsipalaiduojančios pakeistų chinozolinų vaisto formos |
WO2013190059A1 (en) | 2012-06-21 | 2013-12-27 | Association Institut De Myologie | Widespread gene delivery of gene therapy vectors |
-
2007
- 2007-06-07 CA CA3139726A patent/CA3139726A1/en active Pending
- 2007-06-07 ES ES07795835.3T patent/ES2596885T3/es active Active
- 2007-06-07 TR TR2019/06106T patent/TR201906106T4/tr unknown
- 2007-06-07 EP EP12152550.5A patent/EP2489733B1/en active Active
- 2007-06-07 AR ARP070102460A patent/AR061282A1/es not_active Application Discontinuation
- 2007-06-07 PT PT77958353T patent/PT2029742T/pt unknown
- 2007-06-07 PL PL07795835T patent/PL2029742T3/pl unknown
- 2007-06-07 PL PL12152550T patent/PL2489733T3/pl unknown
- 2007-06-07 RU RU2008152821/10A patent/RU2008152821A/ru not_active Application Discontinuation
- 2007-06-07 EP EP07795835.3A patent/EP2029742B1/en active Active
- 2007-06-07 CN CN200780020891.5A patent/CN101460621B/zh active Active
- 2007-06-07 PT PT12152550T patent/PT2489733T/pt unknown
- 2007-06-07 MX MX2015001403A patent/MX364444B/es unknown
- 2007-06-07 LT LTEP12152550.5T patent/LT2489733T/lt unknown
- 2007-06-07 BR BRPI0711965-8A patent/BRPI0711965A2/pt not_active Application Discontinuation
- 2007-06-07 ES ES12152550T patent/ES2725552T3/es active Active
- 2007-06-07 LT LTEP07795835.3T patent/LT2029742T/lt unknown
- 2007-06-07 SI SI200732107T patent/SI2489733T1/sl unknown
- 2007-06-07 HU HUE12152550 patent/HUE044182T2/hu unknown
- 2007-06-07 HU HUE07795835A patent/HUE031156T2/en unknown
- 2007-06-07 JP JP2009514369A patent/JP2009539847A/ja not_active Withdrawn
- 2007-06-07 CA CA2654292A patent/CA2654292C/en active Active
- 2007-06-07 MX MX2008015530A patent/MX2008015530A/es active IP Right Grant
- 2007-06-07 WO PCT/US2007/013391 patent/WO2007146046A2/en active Application Filing
- 2007-06-07 EP EP19156264.4A patent/EP3540054A3/en active Pending
- 2007-06-07 SI SI200731840A patent/SI2029742T1/sl unknown
-
2008
- 2008-12-02 IL IL195647A patent/IL195647A/en active IP Right Grant
- 2008-12-04 MX MX2019004843A patent/MX2019004843A/es unknown
- 2008-12-04 MX MX2023001965A patent/MX2023001965A/es unknown
- 2008-12-04 US US12/328,267 patent/US9034836B2/en active Active
-
2013
- 2013-08-22 JP JP2013172437A patent/JP2014012697A/ja active Pending
-
2015
- 2015-01-23 JP JP2015011696A patent/JP2015120719A/ja not_active Withdrawn
- 2015-04-21 US US14/692,469 patent/US20160067312A1/en not_active Abandoned
- 2015-10-06 IL IL241890A patent/IL241890A0/en unknown
-
2016
- 2016-10-19 CY CY20161101055T patent/CY1118555T1/el unknown
- 2016-11-10 JP JP2016219801A patent/JP6320489B2/ja active Active
-
2017
- 2017-07-27 AR ARP170102115A patent/AR109171A2/es unknown
-
2018
- 2018-04-03 JP JP2018071383A patent/JP6606215B2/ja active Active
-
2019
- 2019-08-20 US US16/546,070 patent/US11554161B2/en active Active
- 2019-10-17 JP JP2019190202A patent/JP2020079234A/ja active Pending
-
2022
- 2022-12-14 US US18/066,149 patent/US20230364200A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL2489733T3 (pl) | Terapia genowa w stwardnieniu zanikowym bocznym i innych zaburzeniach rdzenia kręgowego | |
LT3146982T (lt) | Amiotrofinės lateralinės sklerozės ir kitų nugaros smegenų sutrikimų genų terapija | |
IL237658A0 (en) | Gene therapy for spinal cord disorders | |
HRP20182147T1 (hr) | Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja | |
EP2010187A4 (en) | CONNECTIONS FOR DISEASES AND FUNCTIONAL DISORDERS | |
HK1205530A1 (en) | Gene expression and pain | |
IL198492A0 (en) | Pathotropic targeted gene delivery system for cancer and other disorders | |
IL197818A0 (en) | Multiple sclerosis therapy | |
GB0406728D0 (en) | Gene therapy | |
SI1879623T1 (sl) | Genska terapija za motnje hrbtenjače | |
EP2059238A4 (en) | THERAPEUTIC COMPOUNDS FOR DISEASES AND DISORDERS | |
IL255035A0 (en) | Gene therapy for spinal cord disorders | |
EP2031066A4 (en) | MUTANT AND COORDINATING GEN | |
GB0616452D0 (en) | Novel therapy for joint disorders | |
AU2006901311A0 (en) | Liver-directed gene therapy |