KR890002547A - Monoclonal antibodies and peptides for the treatment and diagnosis of HIV infection - Google Patents

Monoclonal antibodies and peptides for the treatment and diagnosis of HIV infection

Info

Publication number
KR890002547A
KR890002547A KR1019870009058A KR870009058A KR890002547A KR 890002547 A KR890002547 A KR 890002547A KR 1019870009058 A KR1019870009058 A KR 1019870009058A KR 870009058 A KR870009058 A KR 870009058A KR 890002547 A KR890002547 A KR 890002547A
Authority
KR
South Korea
Prior art keywords
peptides
diagnosis
treatment
monoclonal antibodies
hiv infection
Prior art date
Application number
KR1019870009058A
Other languages
Korean (ko)
Other versions
KR920008744B1 (en
Inventor
캐틀린 스리버 매리
케이. 토머스 엘레인
엘. 코산드 웨슬리
에이치. 고스팅 라리
에스 딕킨슨 에드나
먹클루어 제넬라(엔엠아이)
제이. 토라도 조지
씨. 노윈스키 로버트
Original Assignee
제네틱 시스팀스 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 제네틱 시스팀스 코포레이션 filed Critical 제네틱 시스팀스 코포레이션
Publication of KR890002547A publication Critical patent/KR890002547A/en
Application granted granted Critical
Publication of KR920008744B1 publication Critical patent/KR920008744B1/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
KR1019870009058A 1986-08-20 1987-08-19 Monoclonal antibodies to hiv and related peptides KR920008744B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US898273 1986-08-20
US4502687A 1987-05-01 1987-05-01
US45026 1987-05-01
US6799687A 1987-06-29 1987-06-29
US67996 1987-06-29

Publications (2)

Publication Number Publication Date
KR890002547A true KR890002547A (en) 1989-04-10
KR920008744B1 KR920008744B1 (en) 1992-10-09

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870009058A KR920008744B1 (en) 1986-08-20 1987-08-19 Monoclonal antibodies to hiv and related peptides

Country Status (28)

Country Link
JP (1) JPS6485928A (en)
KR (1) KR920008744B1 (en)
AT (1) AT398080B (en)
AU (1) AU616156B2 (en)
BE (1) BE1000811A4 (en)
CH (1) CH675728A5 (en)
CS (1) CS275838B6 (en)
DE (1) DE3727703A1 (en)
DK (1) DK433087A (en)
ES (1) ES2010727A6 (en)
FI (1) FI873553A (en)
FR (1) FR2603107B1 (en)
GB (1) GB2196634B (en)
GR (1) GR871298B (en)
HU (1) HU214439B (en)
IE (1) IE60671B1 (en)
IL (1) IL83580A (en)
IT (1) IT1222518B (en)
LU (1) LU86972A1 (en)
NL (1) NL8701950A (en)
NO (2) NO300462B1 (en)
NZ (1) NZ221440A (en)
OA (1) OA08652A (en)
PL (1) PL155084B1 (en)
PT (1) PT85567B (en)
SE (1) SE506025C2 (en)
YU (1) YU152587A (en)
ZW (1) ZW15487A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
DE3853779T2 (en) * 1987-05-29 1995-09-07 Tanox Biosystems Inc HIV-1 NEUTRALIZING MONOCLONAL ANTIBODIES.
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
AU621097B2 (en) * 1988-01-26 1992-03-05 United States of America, as represented by the Secretary, U.S. Department of Commerce, The A synthetic antigen evoking anti-hiv response
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (en) * 1988-06-06 1992-04-10 Pasteur Institut PEPTIDES HAVING PROTECTIVE PROPERTIES OF A PATHOGENIC VIRUS OF THE HIV TYPE IN SENSITIVE CELLS
JPH04502760A (en) * 1988-10-03 1992-05-21 レプリゲン・コーポレーション Novel HIV proteins and peptides effective in the diagnosis, prevention and treatment of AIDS
EP0421626A1 (en) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vaccine for aids and hepatitis B
SE9000333D0 (en) * 1990-01-31 1990-01-31 Britta Wahren MONOCLONAL ANTIBODY
SE468168B (en) * 1990-02-20 1992-11-16 Replico Medical Ab HIV-1, P24 PEPTIDES, DIAGNOSTIC ANTIGENS AND PROCEDURES FOR DIFFERENTIAL DIAGNOSTICS OF PRELIMINARY HIV-1 POSITIVE SERUM TESTS
JPH03271233A (en) * 1990-03-19 1991-12-03 Inst Pasteur Inducement of protective action against virus infection by synergism between peptides cor- responding to virus envelope glycoprotein and neutral epitope of its glycoprotein
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (en) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv-related cyclic peptide and adsorption material obtained by immobilizing the same
DE69333537T2 (en) * 1992-03-27 2005-06-16 Advanced Immuni T, Inc. T-peptide and related peptides in the treatment of inflammation, including multiple sclerosis
US8470778B2 (en) 2005-12-09 2013-06-25 Vectus Biosystems Limited VIP fragments and methods of use
WO2010026940A1 (en) 2008-09-02 2010-03-11 日本特殊陶業株式会社 Spark plug

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
ATE250083T1 (en) * 1984-10-18 2003-10-15 Pasteur Institut LAV ANTIGENS AND PEPTIDES
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
EP0220234B1 (en) * 1985-04-08 1994-08-03 Genetic Systems Corporation EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
NZ215867A (en) * 1985-04-19 1989-10-27 Hoffmann La Roche Aids envelope protein, dna vectors and method of production
DE3650175T3 (en) * 1985-04-29 2007-09-06 Bio-Rad Laboratories, Inc., Hercules SYNTHETIC ANTIGENIC TO IDENTIFY AIDS.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
DE3689941D1 (en) * 1985-10-24 1994-08-04 Southwest Found Biomed Res SYNTHETIC PEPTIDES AND THEIR USE FOR DIAGNOSIS AND VACCINATION FOR AIDS AND ARC.
JP2837669B2 (en) * 1985-11-07 1998-12-16 プレジデント アンド フエロウズ オブ ハ−バ−ド カレツジ T-cell lymphotropic virus protein and its analysis
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (en) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Human monoclonal antibody capable of reacting with an epitope on the LAV / HTLV-III envelope glycoprotein gp41, cell lines producing such antibody, pharmaceutical preparation containing the antibody, and method for determining the presence of LAV / HTLV-III in a biological sample. and method for separating specific antigenic determinants of LAV / HTLV-III using ant
EP0255190A3 (en) * 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
JPH0762031B2 (en) * 1986-12-30 1995-07-05 アメリカ合衆国 Synthetic peptides that induce cell-mediated immunity to AIDS virus and AIDS virus proteins

Also Published As

Publication number Publication date
PL155084B1 (en) 1991-10-31
PT85567A (en) 1987-09-01
CS8706136A2 (en) 1990-08-14
SE8703225D0 (en) 1987-08-19
NO934897D0 (en) 1993-12-29
PL267401A1 (en) 1988-07-21
FI873553A0 (en) 1987-08-17
GB2196634B (en) 1991-05-15
DK433087D0 (en) 1987-08-19
CS275838B6 (en) 1992-03-18
NO300462B1 (en) 1997-06-02
SE506025C2 (en) 1997-11-03
IT1222518B (en) 1990-09-05
ATA208987A (en) 1994-01-15
BE1000811A4 (en) 1989-04-11
SE8703225L (en) 1988-02-21
NO934897L (en) 1993-12-29
DK433087A (en) 1988-02-21
GB8719587D0 (en) 1987-09-23
GB2196634A (en) 1988-05-05
DE3727703A1 (en) 1988-05-05
NO302176B1 (en) 1998-02-02
YU152587A (en) 1992-09-07
FR2603107A1 (en) 1988-02-26
FR2603107B1 (en) 1992-04-24
NZ221440A (en) 1991-11-26
OA08652A (en) 1988-11-30
AT398080B (en) 1994-09-26
IT8721678A0 (en) 1987-08-19
CH675728A5 (en) 1990-10-31
IE872219L (en) 1988-02-20
NO873495L (en) 1988-02-22
ZW15487A1 (en) 1988-09-14
IL83580A0 (en) 1988-01-31
HUT44619A (en) 1988-03-28
FI873553A (en) 1988-02-21
IE60671B1 (en) 1994-08-10
IL83580A (en) 1992-11-15
AU616156B2 (en) 1991-10-24
AU7720187A (en) 1988-05-19
NL8701950A (en) 1988-03-16
JPS6485928A (en) 1989-03-30
GR871298B (en) 1988-01-12
KR920008744B1 (en) 1992-10-09
LU86972A1 (en) 1988-03-02
ES2010727A6 (en) 1989-12-01
PT85567B (en) 1991-02-08
HU214439B (en) 1998-03-30
NO873495D0 (en) 1987-08-19

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Legal Events

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E902 Notification of reason for refusal
G160 Decision to publish patent application
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GRNT Written decision to grant
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Payment date: 19970830

Year of fee payment: 6

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