HUT44619A - Process for preparing monoclonal antibodies and peptides suitable for the treatment and detection of hiv infections - Google Patents

Process for preparing monoclonal antibodies and peptides suitable for the treatment and detection of hiv infections

Info

Publication number
HUT44619A
HUT44619A HU873707A HU370787A HUT44619A HU T44619 A HUT44619 A HU T44619A HU 873707 A HU873707 A HU 873707A HU 370787 A HU370787 A HU 370787A HU T44619 A HUT44619 A HU T44619A
Authority
HU
Hungary
Prior art keywords
detection
treatment
monoclonal antibodies
hiv infections
preparing monoclonal
Prior art date
Application number
HU873707A
Other languages
Hungarian (hu)
Other versions
HU214439B (en
Inventor
Mary K Shriver
Jarry H Gosting
Edna S Dickinson
Janela Mcclure
Elaine K Thomas
Wesley L Cosand
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of HUT44619A publication Critical patent/HUT44619A/en
Publication of HU214439B publication Critical patent/HU214439B/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU873707A 1986-08-20 1987-08-19 Method for the production of monoclonal antibodies and peptids useful in treating hiv infections and for the production of pharmaceutical compositions and vaccines HU214439B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (2)

Publication Number Publication Date
HUT44619A true HUT44619A (en) 1988-03-28
HU214439B HU214439B (en) 1998-03-30

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
HU873707A HU214439B (en) 1986-08-20 1987-08-19 Method for the production of monoclonal antibodies and peptids useful in treating hiv infections and for the production of pharmaceutical compositions and vaccines

Country Status (28)

Country Link
JP (1) JPS6485928A (en)
KR (1) KR920008744B1 (en)
AT (1) AT398080B (en)
AU (1) AU616156B2 (en)
BE (1) BE1000811A4 (en)
CH (1) CH675728A5 (en)
CS (1) CS275838B6 (en)
DE (1) DE3727703A1 (en)
DK (1) DK433087A (en)
ES (1) ES2010727A6 (en)
FI (1) FI873553A (en)
FR (1) FR2603107B1 (en)
GB (1) GB2196634B (en)
GR (1) GR871298B (en)
HU (1) HU214439B (en)
IE (1) IE60671B1 (en)
IL (1) IL83580A (en)
IT (1) IT1222518B (en)
LU (1) LU86972A1 (en)
NL (1) NL8701950A (en)
NO (2) NO300462B1 (en)
NZ (1) NZ221440A (en)
OA (1) OA08652A (en)
PL (1) PL155084B1 (en)
PT (1) PT85567B (en)
SE (1) SE506025C2 (en)
YU (1) YU152587A (en)
ZW (1) ZW15487A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
CA1339857C (en) * 1987-05-29 1998-05-05 Cecily Rou-Yun Sun Monoclonal antibodies to gp120 which neutraleze hiv-1
JP2569185B2 (en) * 1988-01-26 1997-01-08 アメリカ合衆国 Synthetic antigen eliciting anti-HIV response
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (en) * 1988-06-06 1992-04-10 Pasteur Institut PEPTIDES HAVING PROTECTIVE PROPERTIES OF A PATHOGENIC VIRUS OF THE HIV TYPE IN SENSITIVE CELLS
JPH04502760A (en) * 1988-10-03 1992-05-21 レプリゲン・コーポレーション Novel HIV proteins and peptides effective in the diagnosis, prevention and treatment of AIDS
CA2025481A1 (en) * 1989-09-19 1991-03-20 Peter J. Kniskern Vaccine for aids and hepatitis b
SE9000333D0 (en) * 1990-01-31 1990-01-31 Britta Wahren MONOCLONAL ANTIBODY
SE468168B (en) * 1990-02-20 1992-11-16 Replico Medical Ab HIV-1, P24 PEPTIDES, DIAGNOSTIC ANTIGENS AND PROCEDURES FOR DIFFERENTIAL DIAGNOSTICS OF PRELIMINARY HIV-1 POSITIVE SERUM TESTS
JPH03271233A (en) * 1990-03-19 1991-12-03 Inst Pasteur Inducement of protective action against virus infection by synergism between peptides cor- responding to virus envelope glycoprotein and neutral epitope of its glycoprotein
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (en) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv-related cyclic peptide and adsorption material obtained by immobilizing the same
DE69333537T2 (en) * 1992-03-27 2005-06-16 Advanced Immuni T, Inc. T-peptide and related peptides in the treatment of inflammation, including multiple sclerosis
CA2952475C (en) 2005-12-09 2022-08-09 Vectus Biosystems Limited Vip fragment for the treatment of myocardial fibrosis
KR101215215B1 (en) 2008-09-02 2012-12-24 니혼도꾸슈도교 가부시키가이샤 Spark Plug

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
DE122005000039I1 (en) * 1984-10-18 2006-02-23 Pasteur Institut DNA fragments of the GAG gene of LAV
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
DE3650011T2 (en) * 1985-04-08 1994-11-17 Genetic Systems Corp EXPRESSION AND DIAGNOSIS WITH GAG-CODED PEPTIDES THAT ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES AGAINST LAV.
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
DK171119B1 (en) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS virus envelope protein, expression vector carrying the envelope protein, transformants transformed with the expression vector, method of producing the virus envelope protein, method of detecting AIDS antibodies, method of determining AIDS virus, vaccine against AIDS, antibodies against the virus envelope protein and use of it to prepare a vaccine and for testing
ATE116006T1 (en) * 1985-04-29 1995-01-15 Genetic Systems Corp SYNTHETIC ANTIGENS FOR DETECTING AIDS.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
WO1987002775A1 (en) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Synthetic peptides and use for diagnosis and vaccination for aids and arc
JP2837669B2 (en) * 1985-11-07 1998-12-16 プレジデント アンド フエロウズ オブ ハ−バ−ド カレツジ T-cell lymphotropic virus protein and its analysis
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
EP0255190A3 (en) * 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
JPH0762031B2 (en) * 1986-12-30 1995-07-05 アメリカ合衆国 Synthetic peptides that induce cell-mediated immunity to AIDS virus and AIDS virus proteins

Also Published As

Publication number Publication date
KR920008744B1 (en) 1992-10-09
NO934897D0 (en) 1993-12-29
FI873553A0 (en) 1987-08-17
CS8706136A2 (en) 1990-08-14
KR890002547A (en) 1989-04-10
OA08652A (en) 1988-11-30
NO302176B1 (en) 1998-02-02
FR2603107A1 (en) 1988-02-26
ATA208987A (en) 1994-01-15
GR871298B (en) 1988-01-12
NO873495L (en) 1988-02-22
IL83580A (en) 1992-11-15
BE1000811A4 (en) 1989-04-11
GB2196634A (en) 1988-05-05
JPS6485928A (en) 1989-03-30
LU86972A1 (en) 1988-03-02
IT8721678A0 (en) 1987-08-19
PT85567A (en) 1987-09-01
AT398080B (en) 1994-09-26
SE8703225L (en) 1988-02-21
NO300462B1 (en) 1997-06-02
FI873553A (en) 1988-02-21
DK433087D0 (en) 1987-08-19
IE872219L (en) 1988-02-20
NZ221440A (en) 1991-11-26
ZW15487A1 (en) 1988-09-14
NL8701950A (en) 1988-03-16
IE60671B1 (en) 1994-08-10
NO873495D0 (en) 1987-08-19
CH675728A5 (en) 1990-10-31
PL267401A1 (en) 1988-07-21
DE3727703A1 (en) 1988-05-05
CS275838B6 (en) 1992-03-18
AU616156B2 (en) 1991-10-24
IL83580A0 (en) 1988-01-31
PT85567B (en) 1991-02-08
ES2010727A6 (en) 1989-12-01
NO934897L (en) 1993-12-29
YU152587A (en) 1992-09-07
IT1222518B (en) 1990-09-05
AU7720187A (en) 1988-05-19
SE8703225D0 (en) 1987-08-19
HU214439B (en) 1998-03-30
GB8719587D0 (en) 1987-09-23
SE506025C2 (en) 1997-11-03
PL155084B1 (en) 1991-10-31
FR2603107B1 (en) 1992-04-24
DK433087A (en) 1988-02-21
GB2196634B (en) 1991-05-15

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee