KR870008848A - 페닐우레아의 제조방법 - Google Patents
페닐우레아의 제조방법 Download PDFInfo
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- KR870008848A KR870008848A KR870002415A KR870002415A KR870008848A KR 870008848 A KR870008848 A KR 870008848A KR 870002415 A KR870002415 A KR 870002415A KR 870002415 A KR870002415 A KR 870002415A KR 870008848 A KR870008848 A KR 870008848A
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
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- C07—ORGANIC CHEMISTRY
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- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (7)
- a) 하기의 구조식(Ⅰ)의 화합물을 하기의 구조식(Ⅱ)의 화합물과 반응시키거나, 또는b) 하기의 구조식(Ⅲ)의 벤즈아미드를 하기의 구조식(Ⅳ)의 화합물과 반응시키는 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.식중, X1, X2, X3및 X5는 각각 수소, 할로겐 또는 C1-4알킬이고,X4는 수소, 할로겐, 비치환 또는 할로겐화 C1-4알킬 또는 COOR이고,X6은 수소, 할로겐, C1-8알킬 또는 COOR´이고,Y는 산소 또는 황이고,A는 질소 또는 C-R4이고,B는 질소 또는 C-R3이고,R1및 R4는 각각 수소, 할로겐, 할로겐화 C1-8알킬, 비치환 또는 할로겐화 C1-8알콕시, 비치환 또는 할로겐화 C1-8알킬티오, 또는 비치환 또는 1 내지 4개의 할로겐원자로 치환되거나 하나의 CF3, C1-4알킬 또는 C1-4알콕시기와 0 내지 3개의 할로겐 원자로 치환된 아릴, 아릴옥시 또는 아릴티오이고,R2및 R3는 각각 수소, 할로겐, 시아노, 비치환 또는 할로겐화 C1-8알킬, 비치환 또는 할로겐화 C1-8알콕시, 비치환 또는 할로겐화 C1-8알킬티오, COOR˝, 비치환 또는 1 내지 4개의 할로겐 원자로 치환되거나 하나의 C1-4알킬, C1-4알콕시 또는 CF3기와 0 내지 3개의 할로겐원자로 치환된 아릴, 알콕시 또는 아릴티오이고,또는 R1및 R2또는 R2및 R3는 공히 4개의 탄소원자로 이루어진 포화 또는 불포화의 가교기를 형성할 수 있고, 경우에 따라서 1 내지 4개의 할로겐 원자로 치환되거나 하나의 트리플루오로메틸기와 0 내지 3개의 할로겐 원자로 치환 가능하고,R,R´및 R˝는 각각 수소 또는 C1-8알킬이고,A가 C-R4이고 B가 C-R3인 경우에는 R1,R2,R3및 R4모두가 수소는 아니다.
- 제 1 항에 있어서, A는 질소이고 B는 C-R3인 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.
- 제 1 항 또는 제 2 항에 있어서, 아릴, 아릴옥시 또는 아릴티오는 비치환 또는 하나의 메틸, 메톡시 또는 CF3기와 0 또는 1개의 할로겐 또는 1 또는 2개의 할로겐으로 단일치환 또는 이치환되어서 아릴, 아릴옥시 및 아릴티오는 나프틸, 페닐, 피리딜 또는 티에닐을 표시하는 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.
- 제 3 항에 있어서, Y노 0인 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.
- 제 3 항 또는 제 4 항에 있어서, X1, X2및 X3는 각각 H 또는 할로겐이고, X4는 H, 할로겐, CH3또는 CF3이고, X5는 H, 할로겐 또는 CH3이고, X6은 H 또는 할로겐이고, R1및 R2는 각각 H, 할로겐 또는 CF3이고, R3는 H, 할로겐, C1-4알킬 또는 CF3이고, R1, R2및 R3중의 하나는 할로페닐, 디할로페닐, 메틸페닐 또는 트리플루오로메틸페닐일 수 있고, 또는 R1과 R2가 공히 비치환, 단일치환 또는 이치환된 구조식 CH=CH-CH=CH의 가교기를 형성하거나, 또는 R2와 R3가 공히 구조식(CH2)4의 가교기를 형성하는 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.
- 제 5 항에 있어서, X1은 할로겐이고, X3및 X6은 H이고, X4는 할로겐, CH3또는 CF3이고, X5는 할로겐 또는 CH3이고, R3는 H, 할로겐, CF|3또는 할로페닐인 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.
- 제 6 항에 있어서, 구조식(A)의 화합물은 하기의 화합물 중에서 선택되는 것을 특징으로 하는 구조식(A)의 화합물의 제조방법.a) N-3,5-디클로로-4-[4-클로로-3-(4-클로로페닐)-1-피라졸일]페닐-N´-2,6-디플루오로벤조일우레아b) N-3,5-디메틸-4-[4-클로로-3-(4-클로로페닐)-1-피라졸일]페닐-N´-2,6-디플루오로벤조일우레아c) N-3,5-디클로로-4-(4-브로모-1-피라졸일)-페닐-N´-2-클로로벤조일우레아d) N-3,5-디클로로-4-(3,4-디브로모-1-피라졸일)페닐-N´-2-클로로벤조일우레아e) N-3,5-디클로로-4-(4,5-디클로로-3-트리플루오로메틸-1-피라졸일) 페닐-N´-2-클로로벤조일우레아f) N-3,5-디클로로-4-[3-(4-클로로페닐)-1-피라졸일] 페닐-N´-2-클로로벤조일우레아g) N-3,5-디클로로-4-(3,4,5-트리클로로-1-피라졸일)페닐-N´-2-클로로벤조 일우레아h) N-3,5-디클로로-4-(4,5-디클로로-3-트리플루오로메틸-1-피라졸일) 페닐-N´-2-플루오로벤조일우레아i) N-3,5-디클로로-4-[3-(4-브로모페닐)-1-피라졸일]페닐-N´-2-플루오로벤조 일우레아※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84081486A | 1986-03-18 | 1986-03-18 | |
US840814 | 1986-03-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870008848A true KR870008848A (ko) | 1987-10-21 |
KR910000042B1 KR910000042B1 (ko) | 1991-01-19 |
Family
ID=25283301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870002415A KR910000042B1 (ko) | 1986-03-18 | 1987-03-16 | 페닐우레아 및 그 제조방법 |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0242322B1 (ko) |
JP (1) | JPS62230765A (ko) |
KR (1) | KR910000042B1 (ko) |
CN (1) | CN1017397B (ko) |
AT (1) | ATE83477T1 (ko) |
AU (1) | AU602884B2 (ko) |
BR (1) | BR8701205A (ko) |
DE (1) | DE3783070T2 (ko) |
DK (1) | DK134587A (ko) |
EG (1) | EG18296A (ko) |
ES (1) | ES2053579T3 (ko) |
GR (1) | GR3007051T3 (ko) |
HU (1) | HU203945B (ko) |
IE (1) | IE60258B1 (ko) |
IL (1) | IL81900A0 (ko) |
MY (1) | MY101169A (ko) |
NZ (1) | NZ219623A (ko) |
PT (1) | PT84498B (ko) |
SU (1) | SU1491333A3 (ko) |
TR (1) | TR23211A (ko) |
ZA (1) | ZA871996B (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5187185A (en) * | 1988-12-09 | 1993-02-16 | Rhone-Poulenc Ag Company | Pesticidal 1-arylpyrroles |
DE3712934A1 (de) * | 1987-04-16 | 1988-11-03 | Bayer Ag | Substituierte 1-arylpyrazole |
DE3715703A1 (de) * | 1987-05-12 | 1988-11-24 | Bayer Ag | 1-aryl-3-halogenalkyl-4-halogen-pyrazole |
DE3927483A1 (de) * | 1989-08-19 | 1991-02-21 | Boehringer Ingelheim Kg | Neue substituierte heterocyclische fuenfringe, ihre herstellung und verwendung |
US6506747B1 (en) * | 1998-06-05 | 2003-01-14 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents |
JP2006502247A (ja) * | 2002-07-12 | 2006-01-19 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 複素環で置換されたベンゾイル尿素、その製造方法および医薬としてのその使用 |
RU2597421C2 (ru) * | 2011-02-07 | 2016-09-10 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и связанные с ними способы |
CN107176951A (zh) * | 2016-03-11 | 2017-09-19 | 恩瑞生物医药科技(上海)有限公司 | 一种脲类化合物、其制备方法及其医药用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4560770A (en) * | 1983-02-09 | 1985-12-24 | Ciba-Geigy Corporation | Pesticidal compositions based on N-pyrrolylphenyl-N'-benzoylurea compounds |
DE3423582A1 (de) * | 1984-06-27 | 1986-01-09 | Bayer Ag, 5090 Leverkusen | Substituierte 5-acylamino-1-phenylpyrazole |
-
1987
- 1987-03-11 AT AT87810137T patent/ATE83477T1/de not_active IP Right Cessation
- 1987-03-11 EP EP87810137A patent/EP0242322B1/en not_active Expired - Lifetime
- 1987-03-11 ES ES87810137T patent/ES2053579T3/es not_active Expired - Lifetime
- 1987-03-11 DE DE8787810137T patent/DE3783070T2/de not_active Expired - Fee Related
- 1987-03-16 IE IE68187A patent/IE60258B1/en not_active IP Right Cessation
- 1987-03-16 NZ NZ219623A patent/NZ219623A/xx unknown
- 1987-03-16 MY MYPI87000302A patent/MY101169A/en unknown
- 1987-03-16 DK DK134587A patent/DK134587A/da not_active Application Discontinuation
- 1987-03-16 KR KR1019870002415A patent/KR910000042B1/ko not_active IP Right Cessation
- 1987-03-16 AU AU70048/87A patent/AU602884B2/en not_active Ceased
- 1987-03-16 IL IL81900A patent/IL81900A0/xx not_active IP Right Cessation
- 1987-03-16 EG EG155/87A patent/EG18296A/xx active
- 1987-03-17 JP JP62065533A patent/JPS62230765A/ja active Pending
- 1987-03-17 PT PT84498A patent/PT84498B/pt not_active IP Right Cessation
- 1987-03-17 CN CN87102145A patent/CN1017397B/zh not_active Expired
- 1987-03-17 SU SU874202182A patent/SU1491333A3/ru active
- 1987-03-17 BR BR8701205A patent/BR8701205A/pt unknown
- 1987-03-17 HU HU871157A patent/HU203945B/hu not_active IP Right Cessation
- 1987-03-18 ZA ZA871996A patent/ZA871996B/xx unknown
- 1987-03-18 TR TR177/87A patent/TR23211A/xx unknown
-
1993
- 1993-02-11 GR GR930400283T patent/GR3007051T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HUT43941A (en) | 1988-01-28 |
EG18296A (en) | 1992-10-30 |
KR910000042B1 (ko) | 1991-01-19 |
EP0242322A2 (en) | 1987-10-21 |
HU203945B (en) | 1991-11-28 |
ES2053579T3 (es) | 1994-08-01 |
DK134587A (da) | 1987-09-19 |
AU7004887A (en) | 1987-09-24 |
EP0242322B1 (en) | 1992-12-16 |
AU602884B2 (en) | 1990-11-01 |
JPS62230765A (ja) | 1987-10-09 |
EP0242322A3 (en) | 1989-03-22 |
NZ219623A (en) | 1990-09-26 |
DK134587D0 (da) | 1987-03-16 |
IE60258B1 (en) | 1994-06-29 |
IL81900A0 (en) | 1987-10-20 |
ZA871996B (en) | 1988-10-26 |
TR23211A (tr) | 1989-06-21 |
IE870681L (en) | 1987-09-18 |
PT84498B (pt) | 1989-11-10 |
MY101169A (en) | 1991-07-31 |
CN1017397B (zh) | 1992-07-15 |
DE3783070D1 (en) | 1993-01-28 |
DE3783070T2 (de) | 1993-05-13 |
CN87102145A (zh) | 1987-09-30 |
PT84498A (en) | 1987-04-01 |
GR3007051T3 (ko) | 1993-07-30 |
ATE83477T1 (de) | 1993-01-15 |
BR8701205A (pt) | 1988-01-12 |
SU1491333A3 (ru) | 1989-06-30 |
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