KR860002267A - 국소용 경피 마취조성물의 제조방법 - Google Patents

국소용 경피 마취조성물의 제조방법 Download PDF

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Publication number
KR860002267A
KR860002267A KR1019850006446A KR850006446A KR860002267A KR 860002267 A KR860002267 A KR 860002267A KR 1019850006446 A KR1019850006446 A KR 1019850006446A KR 850006446 A KR850006446 A KR 850006446A KR 860002267 A KR860002267 A KR 860002267A
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KR
South Korea
Prior art keywords
composition
weight
anesthetic
gelling agent
total weight
Prior art date
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KR1019850006446A
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English (en)
Inventor
맥카퍼티(외 1) 더모트
Original Assignee
원본미기재
쏘시에떼 데뛰드 시앙띠훠크에 앵뒤스트리엘드 일-드-프랑스
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10566481&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR860002267(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 원본미기재, 쏘시에떼 데뛰드 시앙띠훠크에 앵뒤스트리엘드 일-드-프랑스 filed Critical 원본미기재
Publication of KR860002267A publication Critical patent/KR860002267A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Pipeline Systems (AREA)
  • Vehicle Body Suspensions (AREA)
  • Indication And Recording Devices For Special Purposes And Tariff Metering Devices (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

내용 없음

Description

국소용 경피 마취조성물의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 국소용으로, 아메도카인, 수성겔화제 및 물을 혼합하여 구성되는데, 여기서 겔이 형성되고, 아메도카인은 저장동안에는 가수분해로부터 보호되고 조성물이 피부에 적용되었을대 녹고 흡수에 유용하도록, 아메도카인은 완전히 분산된 고체상으로 듀지되는 조성물을 제조하는 방법.
  2. 제1항에 있어서, 사용하였을때, 마취제는 녹아서 침투가 촉진되도록 겔을 통해 분산되고, 마취제, 마취제를 안정화하는 수성겔화제 및 물로 구성되는 국소용 경피마취제 조성물의 제조방법.
  3. 제2항에 있어서, 마취제는 아메도카인인 조성물의 제조방법.
  4. 제3항에 있어서, 조성물의 전체무게에 기초하여 1내지 7%무게의 마취제로 구성되는 조성물의 제조방법.
  5. 제2항에 있어서, 조성물의 전체무게에 기초하여 0.5내지 10%무게의 수성겔화제로 구성되는 조성물의 제조방법.
  6. 제5항에 있어서, 수성겔화제는 카보머인 구성되는 조성물의 제조방법.
  7. 제6항에 있어서, 조성물의 전체무게에 기초하여 0.5내지 2%무게의 카보머로 구성되는 조성물의 제조방법.
  8. 제5항에 있어서, 수성겔화제는 메틸셀룰로우스인 조성물의 제조방법.
  9. 제8항에 있어서, 조성물의 전체무게에 기초하여 3 내지 10%무게의 메팀셀룰로우스로 구성되는 조성물의 제조방법.
  10. 제2항에 있어서, 조성물의 전체무게에 기초하여 81내지 94.5%무게의 물로 구성되는 조성물의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850006446A 1984-09-08 1985-09-04 국소용 경피 마취조성물의 제조방법 KR860002267A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB08422759A GB2163956B (en) 1984-09-08 1984-09-08 Percutaneous anaesthetic composition for topical application
GB8422759 1984-09-08

Publications (1)

Publication Number Publication Date
KR860002267A true KR860002267A (ko) 1986-04-24

Family

ID=10566481

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850006446A KR860002267A (ko) 1984-09-08 1985-09-04 국소용 경피 마취조성물의 제조방법

Country Status (31)

Country Link
EP (1) EP0175609B1 (ko)
JP (1) JPS6185316A (ko)
KR (1) KR860002267A (ko)
AT (1) ATE73352T1 (ko)
AU (1) AU581246B2 (ko)
BE (1) BE903186A (ko)
CH (1) CH666815A5 (ko)
CS (1) CS261887B2 (ko)
DD (1) DD236876A5 (ko)
DE (2) DE3531002A1 (ko)
DK (1) DK406785A (ko)
FI (1) FI853416L (ko)
FR (1) FR2569982B1 (ko)
GB (1) GB2163956B (ko)
GR (1) GR852142B (ko)
HU (1) HU193611B (ko)
IL (1) IL76092A0 (ko)
IN (1) IN165072B (ko)
IS (1) IS3035A7 (ko)
IT (1) IT1182854B (ko)
LU (1) LU86068A1 (ko)
MA (1) MA20519A1 (ko)
NO (1) NO853504L (ko)
NZ (1) NZ213325A (ko)
OA (1) OA08158A (ko)
PH (1) PH21731A (ko)
PL (1) PL255285A1 (ko)
PT (1) PT81079B (ko)
ZA (1) ZA856501B (ko)
ZM (1) ZM6185A1 (ko)
ZW (1) ZW14285A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030083316A (ko) * 2002-04-20 2003-10-30 김성수 인두의 국소마취를 위한 고형 리도케인 제제

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8712518D0 (en) * 1987-05-28 1987-07-01 Univ Belfast Unit-dose film composition
GB8729855D0 (en) * 1987-12-22 1988-02-03 Drythanol Ltd New dithranol compositions
GB9101986D0 (en) * 1991-01-30 1991-03-13 Smith & Nephew Pharmaceutical compositions
SE9402453D0 (sv) * 1994-07-12 1994-07-12 Astra Ab New pharmaceutical preparation
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US6284266B1 (en) 1995-07-28 2001-09-04 Zars, Inc. Methods and apparatus for improved administration of fentanyl and sufentanil
US5658583A (en) * 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US6955819B2 (en) 1998-09-29 2005-10-18 Zars, Inc. Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
US6453648B1 (en) 1999-07-06 2002-09-24 Zars, Inc. Method for manufacturing a heat generating apparatus
US6261595B1 (en) 2000-02-29 2001-07-17 Zars, Inc. Transdermal drug patch with attached pocket for controlled heating device
DK2117521T3 (da) 2006-11-03 2012-09-03 Durect Corp Transdermale indgivelsessystemer omfattende bupivacain
JP5648174B2 (ja) 2009-05-04 2015-01-07 ヌボ リサーチ インコーポレイテッド 神経腫、神経絞扼、および他の状態と関連する疼痛を処置する方法
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB633062A (en) * 1945-02-01 1949-12-12 Benjamin Clayton Improvements in or relating to ointment bases
GB948838A (en) * 1961-12-04 1964-02-05 Lucien Harnist Hemorrhoidal compositions containing topical anesthetics
US3337406A (en) * 1963-12-12 1967-08-22 Mar Sal Inc Treatment of arteriosclerotic diseases
SE387536B (sv) * 1973-03-13 1976-09-13 Astra Laekemedel Ab Forfarande for framstellning av en lokalanestetisk beredning
DE2413143A1 (de) * 1974-03-19 1975-10-09 Inst Chimii Drevesiny Akademii Arzneipraeparat mit lokalanaesthetischer wirkung
JPS5467022A (en) * 1977-11-07 1979-05-30 Toko Yakuhin Kogyo Kk Topical agent and production thereof
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
DE3234350A1 (de) * 1982-09-16 1984-03-22 Roland 3400 Göttingen Hemmann Verfahren zur herstellung eines keimtoetenden und oberflaechenanaesthesierenden heilmittels

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030083316A (ko) * 2002-04-20 2003-10-30 김성수 인두의 국소마취를 위한 고형 리도케인 제제

Also Published As

Publication number Publication date
PL255285A1 (en) 1988-03-31
AU4700685A (en) 1986-03-13
GB8422759D0 (en) 1984-10-10
ZW14285A1 (en) 1986-01-29
HUT39360A (en) 1986-09-29
CS261887B2 (en) 1989-02-10
ZA856501B (en) 1986-05-28
PT81079A (en) 1985-10-01
ZM6185A1 (en) 1986-01-23
CS635685A2 (en) 1988-06-15
DE3585580D1 (de) 1992-04-16
DK406785D0 (da) 1985-09-06
EP0175609A2 (fr) 1986-03-26
IT8548529A0 (it) 1985-09-05
IN165072B (ko) 1989-08-12
AU581246B2 (en) 1989-02-16
DK406785A (da) 1986-03-09
PT81079B (pt) 1987-10-20
EP0175609A3 (en) 1987-01-28
JPS6185316A (ja) 1986-04-30
DD236876A5 (de) 1986-06-25
PH21731A (en) 1988-02-10
NO853504L (no) 1986-03-10
IT1182854B (it) 1987-10-05
FI853416L (fi) 1986-03-09
IS3035A7 (is) 1986-03-09
OA08158A (fr) 1987-03-31
DE3531002A1 (de) 1986-03-20
BE903186A (fr) 1986-03-05
MA20519A1 (fr) 1986-04-01
FR2569982A1 (fr) 1986-03-14
FR2569982B1 (fr) 1988-03-25
GR852142B (ko) 1985-12-24
EP0175609B1 (fr) 1992-03-11
GB2163956B (en) 1988-03-30
LU86068A1 (fr) 1986-03-11
HU193611B (en) 1987-11-30
IL76092A0 (en) 1985-12-31
NZ213325A (en) 1989-06-28
CH666815A5 (fr) 1988-08-31
GB2163956A (en) 1986-03-12
FI853416A0 (fi) 1985-09-06
ATE73352T1 (de) 1992-03-15

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