KR850004386A - 유효 화합물 방출 조성체 제조방법 - Google Patents
유효 화합물 방출 조성체 제조방법 Download PDFInfo
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- KR850004386A KR850004386A KR1019840008334A KR840008334A KR850004386A KR 850004386 A KR850004386 A KR 850004386A KR 1019840008334 A KR1019840008334 A KR 1019840008334A KR 840008334 A KR840008334 A KR 840008334A KR 850004386 A KR850004386 A KR 850004386A
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- effective compound
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- 239000000203 mixture Substances 0.000 title claims description 7
- 150000001875 compounds Chemical class 0.000 title claims 12
- 238000000034 method Methods 0.000 title claims 10
- 230000001225 therapeutic effect Effects 0.000 claims description 2
- 239000010410 layer Substances 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 6
- 239000011347 resin Substances 0.000 claims 5
- 229920005989 resin Polymers 0.000 claims 5
- 239000011247 coating layer Substances 0.000 claims 4
- 229920003244 diene elastomer Polymers 0.000 claims 4
- 239000004711 α-olefin Substances 0.000 claims 4
- 238000009825 accumulation Methods 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 229920001577 copolymer Polymers 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 125000000547 substituted alkyl group Chemical group 0.000 claims 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims 2
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 150000001993 dienes Chemical class 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 230000009477 glass transition Effects 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims 1
- 229920000089 Cyclic olefin copolymer Polymers 0.000 claims 1
- 229920002943 EPDM rubber Polymers 0.000 claims 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 239000005977 Ethylene Substances 0.000 claims 1
- 229920002367 Polyisobutene Polymers 0.000 claims 1
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims 1
- 230000002745 absorbent Effects 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000007334 copolymerization reaction Methods 0.000 claims 1
- 150000001925 cycloalkenes Chemical class 0.000 claims 1
- -1 fatty acid esters Chemical class 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000007888 film coating Substances 0.000 claims 1
- 238000009501 film coating Methods 0.000 claims 1
- 150000002314 glycerols Chemical class 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 239000011259 mixed solution Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 claims 1
- 150000003097 polyterpenes Chemical class 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000003860 storage Methods 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Control Of Eletrric Generators (AREA)
- Liquid Developers In Electrophotography (AREA)
- External Artificial Organs (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Materials For Medical Uses (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 치료 조성체 제조용 장치의 개략도임. 제2도는 본 발명완성 제품의 단면 도식임.
Claims (10)
- 유효 화합물에 본질적으로 침투되지 않는 피복층, 유효 화합물 축적층 및 필요에 따라 박리시킬 수 있고, 유효 화합물에 본질적으로 침투되지 않는 피복층으로 되는 치료조성체의 제조방법에 있어서, 유리 전이온도 20℃인 고무상과 같은 주로 무정형인 올레핀계 공중합체를 임의로 디엔고무 또는 스티렌/디엔고무와 혼합해서 그 자체로 또는 폴리이소부틸렌의 중합체 성분 50중량%이하와 혼합시킨 혼합물로 되는 중합체 성분, 1이상의 비말동반제 및 1이상의 수지를 용매중에 용해시키고, 유효화합물로서 중합체 성분의 혼합물의 중량에 기초해서 소염제 2―15중량%, 비말동반제 및 수지를 또한 용매중에 용해시키고, 이용액들을 혼합해서 얻은 혼합용액을 유효화합물에 본질적으로 침투되지 않ㄴ느 필름피복층에 고르게 사용하고, 인발시켜 필름을 형성시키고, 피복시킨 필름(회복층)을 처음에 실온에서 건조시킨 다음 50℃이하에서 건조시키고, 필요에 따라 건조시킨 필름(피복층)의 피복층에, 유효화합물에 본질적으로 침투되지 않고 박리시킬 수 있는 보호층을 제공함을 특징으로 하는 치료 조성제의 제조방법.
- 제1항에 있어서, 하기 일반식(Ⅰ) 및 (또는) 일반식(Ⅱ)의 소염제가 유효 화합물로 사용되는 방법:상기식에서, R1―R5는 같거나 서로 다를 수 있는 수소, 할로겐, 서급알킬 또는 치환알킬이고, X는 N 또는 CH이고, Y는 수소, 금속이온, 알킬 또는 치환알킬이고, R은 수소, 저급 알킬 또는 치환알킬이고, Ar은 아릴, 헤테로아릴, 치환아릴 또는 치환헤테로 알릴이고, n+m은 정수로서 0,1 또는 2이고, p는 0 또는 1임. 단 n,m 및 p가 0인 경우에 Ar는 아릴 또는 헤테로아릴을 나타내지 않는다.
- 제1항에 있어서, 하기 일반식의 혼합물이 유효 화합물로 사용되는 방법.
- 제1,2및 3항에 있어서, 유효 화합물 축적층 제조에 있어서, 중합체 성분 30―60중량%, 비말동반제 30―60중량% 및 점착성을 개선시키는 수지 2―20중량%를 사용하고, 이 3성분의 합량이 100%인 방법.
- 제 1,2,3, 및 4항에 있어서, 중합체 성분으로서 디올레핀과더 공중합시킬 수 있고, 20℃이하의 유리전이 온도를 가지며, 그 자체로 또는 α―올레핀류와 랜덤하게 또는 블록형태로 또한 공중합시킬 수 있는 공지의 디엔고무의 중합체 총량 95중량%이하와 혼합시킨 적어도 1이상의 C12―C18―α―올레핀 또는 시클로올레핀으로 되고 주로 무정형인 공중합체를 사용하는 방법.
- 제1,2,3,4 및 5항에 있어서, 중합체 성분으로 에틸렌 및 (또는) 프로필렌과 C4―C18―α―올레핀류로 되는 주로 무정형인 공중합체가 사용되는 방법.
- 제1,2,3,4,5 및 6항에 있어서, 사용된 디엔 고무가 1,3―디엔류에 기초한 것인 방법.
- 제1,2,3,4,5,6 및 7항에 있어서, EPDM 고무가 디엔류와 공중합된 α―올레핀 공중합체로 사용되는 방법.
- 제1,2,3,4,5,7,8항에 있어서, 유효 화합물 축적층에 사용된 필름(피복층)이 흡장성이 굴요성재 또는 비굴요성재로 되는 방법.
- 제1,2,3,4,5,6,7,8 및 9항에 있어서, 폴리테르펜 수지 또는 로진의 변형 글리세롤에 스테르가 유효 화합물 축적용 수지로 사용되고, 오일류, 지방산 에스테르류, 트리글리세리드류, 알코올류 및 (또는) 지방산류가 유효 화합물 축적층용 비말동반 제로서 사용되는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP3347277,7 | 1983-12-28 | ||
DE19833347277 DE3347277A1 (de) | 1983-12-28 | 1983-12-28 | Wirkstoffabgabesysteme |
Publications (1)
Publication Number | Publication Date |
---|---|
KR850004386A true KR850004386A (ko) | 1985-07-15 |
Family
ID=6218283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840008334A KR850004386A (ko) | 1983-12-28 | 1984-12-26 | 유효 화합물 방출 조성체 제조방법 |
Country Status (18)
Country | Link |
---|---|
US (1) | US4661104A (ko) |
EP (1) | EP0150426B1 (ko) |
JP (1) | JPS60158110A (ko) |
KR (1) | KR850004386A (ko) |
AT (1) | ATE57838T1 (ko) |
AU (1) | AU569355B2 (ko) |
CA (1) | CA1240924A (ko) |
DE (2) | DE3347277A1 (ko) |
DK (1) | DK626484A (ko) |
ES (1) | ES8605157A1 (ko) |
FI (1) | FI845133L (ko) |
GR (1) | GR82618B (ko) |
HU (1) | HU193074B (ko) |
IL (1) | IL73936A (ko) |
NO (1) | NO162216B (ko) |
NZ (1) | NZ210689A (ko) |
PT (1) | PT79763B (ko) |
ZA (1) | ZA8410059B (ko) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849226A (en) * | 1981-06-29 | 1989-07-18 | Alza Corporation | Method for increasing oxygen supply by administering vasodilator |
US4812313A (en) * | 1981-06-29 | 1989-03-14 | Alza Corporation | Method for lessening the incidence of anginal attacks |
US4954344A (en) * | 1981-06-29 | 1990-09-04 | Alza Corporation | Method for treating nocturnal angina |
DE3344691A1 (de) * | 1983-12-10 | 1985-06-20 | Bayer Ag, 5090 Leverkusen | Wirkstoffabgasesysteme |
DE3587616D1 (de) * | 1984-12-22 | 1993-11-11 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
JP2572763B2 (ja) * | 1987-04-02 | 1997-01-16 | 帝國製薬株式会社 | エトフェナマ−ト含有貼付薬 |
US5051261A (en) * | 1987-11-24 | 1991-09-24 | Fmc Corporation | Method for preparing a solid sustained release form of a functionally active composition |
US4906475A (en) | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
US5241925A (en) * | 1988-12-27 | 1993-09-07 | Dermamed | Apparatus and techniques for administering veterinary medicaments |
US5332577A (en) * | 1988-12-27 | 1994-07-26 | Dermamed | Transdermal administration to humans and animals |
EP0431519B1 (en) * | 1989-12-04 | 1994-06-15 | G.D. Searle & Co. | System for transdermal albuterol administration |
US5324521A (en) * | 1989-12-18 | 1994-06-28 | Dermamed | Systems for transdermal administration of medicaments |
DK0453603T3 (da) * | 1990-04-26 | 1993-11-22 | Com Pharm Arzneimittel Gmbh | Piroxicamholdige farmaceutiske præparater til topisk anvendelse |
US5580573A (en) * | 1991-02-01 | 1996-12-03 | E. R. Squibb And Sons, Inc. | Temperature activated controlled release |
US5294438A (en) * | 1991-02-05 | 1994-03-15 | Minnesota Mining And Manufacturing Company | Lubricating and moisturizing shaving preparations |
EP0607434B1 (en) * | 1991-08-30 | 1999-01-27 | Hisamitsu Pharmaceutical Co., Inc. | Anti-inflammatory analgesic plaster |
US5264219A (en) * | 1992-08-07 | 1993-11-23 | Minnesota Mining And Manufacturing Company | Transdermal drug delivery backing |
JPH08504146A (ja) * | 1992-12-09 | 1996-05-07 | パステラ,アンソニー・フランシス | 円板状表面スキマーを備えた船舶 |
DE19834025A1 (de) * | 1998-07-28 | 2000-02-03 | Aventis Res & Tech Gmbh & Co | Mikrokapseln hergestellt aus Cycloolefinpolymeren oder Cycloolefincopolymeren und deren Verwendung zur kontrollierten Wirkstoffabgabe |
DE19940238A1 (de) | 1999-08-25 | 2001-03-01 | Lohmann Therapie Syst Lts | Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten |
DE10003767A1 (de) | 2000-01-28 | 2001-10-04 | Beiersdorf Ag | Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung nichtsteroidaler Antirheumatika |
US7704522B2 (en) * | 2004-09-08 | 2010-04-27 | Clyde Morgan | Topical medicament |
CN101080219B (zh) * | 2004-12-15 | 2010-11-17 | 帝国制药株式会社 | 含依托芬那酯的外用贴剂 |
MY148823A (en) * | 2007-01-11 | 2013-06-14 | Drossapharm Ag | Medically active plaster |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
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DE132690C (ko) * | ||||
US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
US3996934A (en) * | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
AR207805A1 (es) * | 1975-02-06 | 1976-10-29 | Alza Corp | Substrato apropiado para formar apositos para la dispensacion continua de escopolamina base por via transdermica |
US4031894A (en) * | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
US4201211A (en) * | 1977-07-12 | 1980-05-06 | Alza Corporation | Therapeutic system for administering clonidine transdermally |
FR2435950A1 (fr) * | 1978-06-05 | 1980-04-11 | Riker Laboratories Inc | Pansement medical comprenant une composition a base de nitroglycerine, sa fabrication et son application |
GB2045618B (en) * | 1979-04-03 | 1983-05-11 | Hisamitsu Pharmaceutical Co | Adhesive plaster |
JPS562909A (en) * | 1979-06-22 | 1981-01-13 | Toyo Ink Mfg Co Ltd | Plaster medicine |
US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
JPS56133381A (en) * | 1980-03-25 | 1981-10-19 | Nippon Kayaku Co Ltd | Pressure-sensitive adhesive tape or sheet containing nitroglycerin |
US4314557A (en) * | 1980-05-19 | 1982-02-09 | Alza Corporation | Dissolution controlled active agent dispenser |
JPS57116011A (en) * | 1981-01-08 | 1982-07-19 | Nitto Electric Ind Co Ltd | Pharmaceutical preparation |
US4379454A (en) * | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
JPS6059207B2 (ja) * | 1981-03-13 | 1985-12-24 | 日東電工株式会社 | 複合製剤の製法 |
US4725272A (en) * | 1981-06-29 | 1988-02-16 | Alza Corporation | Novel bandage for administering beneficial drug |
JPS5867617A (ja) * | 1981-10-17 | 1983-04-22 | Nitto Electric Ind Co Ltd | 消炎鎮痛貼付剤 |
US4420407A (en) * | 1981-10-22 | 1983-12-13 | Texaco Inc. | Method of lubricating upper cylinder of marine diesel engine |
US4435180A (en) * | 1982-05-25 | 1984-03-06 | Alza Corporation | Elastomeric active agent delivery system and method of use |
DE3319469A1 (de) * | 1983-05-28 | 1984-11-29 | Akzo Gmbh, 5600 Wuppertal | System zur transdermalen applikation von pharmakotherapeutisch wirksamen substanzen |
DE3344691A1 (de) * | 1983-12-10 | 1985-06-20 | Bayer Ag, 5090 Leverkusen | Wirkstoffabgasesysteme |
-
1983
- 1983-12-28 DE DE19833347277 patent/DE3347277A1/de not_active Withdrawn
-
1984
- 1984-12-13 AU AU36648/84A patent/AU569355B2/en not_active Ceased
- 1984-12-13 NO NO845001A patent/NO162216B/no unknown
- 1984-12-14 US US06/681,976 patent/US4661104A/en not_active Expired - Fee Related
- 1984-12-18 EP EP84115661A patent/EP0150426B1/de not_active Expired - Lifetime
- 1984-12-18 AT AT84115661T patent/ATE57838T1/de not_active IP Right Cessation
- 1984-12-18 DE DE8484115661T patent/DE3483525D1/de not_active Expired - Lifetime
- 1984-12-20 ES ES538862A patent/ES8605157A1/es not_active Expired
- 1984-12-21 DK DK626484A patent/DK626484A/da not_active Application Discontinuation
- 1984-12-21 NZ NZ210689A patent/NZ210689A/xx unknown
- 1984-12-21 CA CA000470801A patent/CA1240924A/en not_active Expired
- 1984-12-25 IL IL73936A patent/IL73936A/xx unknown
- 1984-12-26 KR KR1019840008334A patent/KR850004386A/ko not_active IP Right Cessation
- 1984-12-27 PT PT79763A patent/PT79763B/pt unknown
- 1984-12-27 ZA ZA8410059A patent/ZA8410059B/xx unknown
- 1984-12-27 FI FI845133A patent/FI845133L/fi not_active Application Discontinuation
- 1984-12-27 JP JP59274219A patent/JPS60158110A/ja active Pending
- 1984-12-28 GR GR82618A patent/GR82618B/el unknown
- 1984-12-28 HU HU844872A patent/HU193074B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4661104A (en) | 1987-04-28 |
NZ210689A (en) | 1988-08-30 |
NO845001L (no) | 1985-07-01 |
ATE57838T1 (de) | 1990-11-15 |
NO162216B (no) | 1989-08-21 |
CA1240924A (en) | 1988-08-23 |
EP0150426B1 (de) | 1990-10-31 |
IL73936A (en) | 1988-09-30 |
DE3483525D1 (de) | 1990-12-06 |
ZA8410059B (en) | 1985-08-28 |
ES8605157A1 (es) | 1986-03-16 |
EP0150426A3 (en) | 1986-01-15 |
PT79763A (en) | 1985-01-01 |
HUT36705A (en) | 1985-10-28 |
AU3664884A (en) | 1985-07-04 |
PT79763B (en) | 1986-10-21 |
AU569355B2 (en) | 1988-01-28 |
DK626484A (da) | 1985-06-29 |
GR82618B (en) | 1985-05-02 |
JPS60158110A (ja) | 1985-08-19 |
ES538862A0 (es) | 1986-03-16 |
EP0150426A2 (de) | 1985-08-07 |
IL73936A0 (en) | 1985-03-31 |
HU193074B (en) | 1987-08-28 |
FI845133A0 (fi) | 1984-12-27 |
DE3347277A1 (de) | 1985-07-11 |
DK626484D0 (da) | 1984-12-21 |
FI845133L (fi) | 1985-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SUBM | Surrender of laid-open application requested |