KR100950432B1 - 개선된 분리법 - Google Patents
개선된 분리법 Download PDFInfo
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- KR100950432B1 KR100950432B1 KR1020047017107A KR20047017107A KR100950432B1 KR 100950432 B1 KR100950432 B1 KR 100950432B1 KR 1020047017107 A KR1020047017107 A KR 1020047017107A KR 20047017107 A KR20047017107 A KR 20047017107A KR 100950432 B1 KR100950432 B1 KR 100950432B1
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- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28078—Pore diameter
- B01J20/28085—Pore diameter being more than 50 nm, i.e. macropores
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
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- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
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- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
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- B01J20/3208—Polymeric carriers, supports or substrates
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- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
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- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
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- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
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- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
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- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
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- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/38—Treatment of water, waste water, or sewage by centrifugal separation
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Abstract
Description
실시예 3 | 실시예 17 | |
LPS 제거 (%) | 81 | 96 |
Claims (34)
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- 하우징(2), 입구(3), 출구(4) 및 하나 이상의 분리 매트릭스(5a, 5b, ...)를 포함하고, 이때 매트릭스는 혈액 또는 체액을 통과시키기 위한 경질의 일체형이고 5㎛ 내지 500㎛ 범위의 기공 크기를 가질 뿐 아니라 하나 이상의 성분을 결합시킬 수 있는 0.5㎠ 내지 10㎡ 범위의 활성 표면을 갖는 다공성 구조를 갖고 소결법, 성형법 및 발포법을 포함하는 그룹으로부터 선택된 방법에 의해 수득된 다공성 구조를 갖는, 체액으로부터 하나 이상의 성분을 선택적으로 결합 및 분리하기 위한 장치.
- 제26항에 있어서, 매트릭스의 기공 크기가 50㎛ 내지 500㎛인 장치.
- 제26항에 있어서, 2개 이상의 분리 매트릭스(5a, 5b, ...)를 갖고, 각각의 매트릭스가 전혈 또는 체액으로부터 하나 이상의 성분을 선택적이고 분리적으로 제거하는 장치.
- 제28항에 있어서, 2개 이상의 분리 매트릭스(5a, 5b, ...)가 체액으로부터 2개 이상의 성분을 제거하는 장치.
- 제29항에 있어서, 제1 분리 매트릭스가 체액으로부터 제1 성분을 제거하고, 제2 분리 매트릭스가 체액으로부터 제2 성분을 제거하는 장치.
- 제28항에 있어서, 하나 이상의 매트릭스의 기공 크기가 50㎛ 내지 500㎛인 장치.
- 제26항에 있어서, 분리 매트릭스의 형태가 디스크, 막대, 실린더, 환, 구, 튜브 또는 중공 튜브 형태인 장치.
- 제26항에 있어서, 분리 매트릭스가 유동 방향으로 연속적으로 배열된 몇몇의 디스크를 포함하여 체액이 하나의 디스크를 통과한 후, 다음 디스크의 전체 표면을 지나 유동하도록 배열되는 장치.
- 제26항에 있어서, 전착, 전기증착, 플라즈마 화학 침착, 이온 플라즈마 유동으로부터의 침착, 플라즈마 중합, 플라즈마 강화된 표면 중합체 침착 및 화학 증착을 포함하는 그룹으로부터 선택되는 방법에 의해 표면 변형이 이루어지는 장치.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201257-3 | 2002-04-25 | ||
SE0201257A SE0201257D0 (sv) | 2002-04-25 | 2002-04-25 | Improved Separation |
PCT/SE2003/000553 WO2003090924A1 (en) | 2002-04-25 | 2003-04-04 | Improved separation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020087010746A Division KR20080044359A (ko) | 2002-04-25 | 2003-04-04 | 수용액으로부터 성분을 선택적으로 제거하기 위한 방법 및장치 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20040104615A KR20040104615A (ko) | 2004-12-10 |
KR100950432B1 true KR100950432B1 (ko) | 2010-04-02 |
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ID=20287687
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020047017107A KR100950432B1 (ko) | 2002-04-25 | 2003-04-04 | 개선된 분리법 |
KR1020087010746A KR20080044359A (ko) | 2002-04-25 | 2003-04-04 | 수용액으로부터 성분을 선택적으로 제거하기 위한 방법 및장치 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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KR1020087010746A KR20080044359A (ko) | 2002-04-25 | 2003-04-04 | 수용액으로부터 성분을 선택적으로 제거하기 위한 방법 및장치 |
Country Status (16)
Country | Link |
---|---|
US (3) | US20030231981A1 (ko) |
EP (2) | EP1704880B1 (ko) |
JP (4) | JP2006508703A (ko) |
KR (2) | KR100950432B1 (ko) |
CN (2) | CN101049522B (ko) |
AT (1) | ATE329687T1 (ko) |
AU (1) | AU2003217134C1 (ko) |
BR (1) | BR0309349A (ko) |
CA (2) | CA2680643A1 (ko) |
DE (2) | DE60306135T2 (ko) |
ES (2) | ES2328386T3 (ko) |
HK (2) | HK1081138A1 (ko) |
MX (1) | MXPA04010543A (ko) |
RU (2) | RU2311183C2 (ko) |
SE (1) | SE0201257D0 (ko) |
WO (1) | WO2003090924A1 (ko) |
Families Citing this family (48)
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WO2005085440A1 (de) * | 2004-03-05 | 2005-09-15 | Sirs-Lab Gmbh | VERFAHREN ZUR ANREICHERUNG UND/ODER ABTRENNUNG VON PROKARYONTER DNA MITTELS EINES PROTEINS, DAS NICHT-METHYLIERTE CpG-MOTIVE ENTHALTENDE DNA SPEZIFISCH BINDET |
EP1792635B1 (en) * | 2004-08-30 | 2014-05-21 | Kaneka Corporation | Granulocyte adsorbent |
WO2006025556A1 (en) * | 2004-08-31 | 2006-03-09 | Showa Denko K.K. | Surface-modified packing material for liquid chromatography and production method thereof |
GB2420976B (en) * | 2004-11-19 | 2006-12-20 | Zvi Finkelstein | Therapeutic implant |
DE102004062535A1 (de) * | 2004-12-24 | 2006-07-06 | Forschungszentrum Karlsruhe Gmbh | Semipermeables Membransystem für magnetische Partikelfraktionen |
JP4821466B2 (ja) * | 2006-07-03 | 2011-11-24 | 富士ゼロックス株式会社 | 液滴吐出ヘッド |
US8165663B2 (en) * | 2007-10-03 | 2012-04-24 | The Invention Science Fund I, Llc | Vasculature and lymphatic system imaging and ablation |
ES2639183T3 (es) | 2007-09-19 | 2017-10-25 | The Charles Stark Draper Laboratory, Inc. | Estructuras microfluídicas con sección transversal circular |
US8285367B2 (en) * | 2007-10-05 | 2012-10-09 | The Invention Science Fund I, Llc | Vasculature and lymphatic system imaging and ablation associated with a reservoir |
US8285366B2 (en) * | 2007-10-04 | 2012-10-09 | The Invention Science Fund I, Llc | Vasculature and lymphatic system imaging and ablation associated with a local bypass |
US7790803B2 (en) * | 2008-06-02 | 2010-09-07 | Uop Llc | Crosslinked organic-inorganic hybrid membranes and their use in gas separation |
US8167871B2 (en) * | 2009-02-25 | 2012-05-01 | The Invention Science Fund I, Llc | Device for actively removing a target cell from blood or lymph of a vertebrate subject |
US8721618B2 (en) | 2009-02-25 | 2014-05-13 | The Invention Science Fund I, Llc | Device for actively removing a target cell from blood or lymph of a vertebrate subject |
US8317737B2 (en) | 2009-02-25 | 2012-11-27 | The Invention Science Fund I, Llc | Device for actively removing a target component from blood or lymph of a vertebrate subject |
US8430831B2 (en) | 2009-02-25 | 2013-04-30 | The Invention Science Fund I, Llc | Device, system, and method for controllably reducing inflammatory mediators in a subject |
DE102009034150A1 (de) * | 2009-07-20 | 2011-01-27 | Fresenius Medical Care Deutschland Gmbh | Adsorbens zur Adsorption von Hepcidin |
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