KR100203759B1 - 신규의 알파-글리코실 나린진 및 그 제조방법과 용도 - Google Patents

신규의 알파-글리코실 나린진 및 그 제조방법과 용도 Download PDF

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Publication number: KR100203759B1
Authority: KR; South Korea
Prior art keywords: naringin; glycosyl; weight; parts; alpha
Prior art date: 1990-04-29

Application number

KR1019910006864A

Other languages

English (en)

Korean (ko)

Other versions

KR910018400A (ko

Inventor

마사루 요네야마

도시오 미야께

Original Assignee

하야시바라 겐

가부시키가이샤 하야시바라 세부쓰 가가쿠 겐쿠쇼

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-29

Filing date

1991-04-29

Publication date

1999-06-15

1991-04-29 Application filed by 하야시바라 겐, 가부시키가이샤 하야시바라 세부쓰 가가쿠 겐쿠쇼 filed Critical 하야시바라 겐

1991-11-30 Publication of KR910018400A publication Critical patent/KR910018400A/ko

1999-02-05 Priority to KR1019990003921A priority Critical patent/KR100227598B1/ko

1999-06-15 Application granted granted Critical

1999-06-15 Publication of KR100203759B1 publication Critical patent/KR100203759B1/ko

Links

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239000001606 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one Substances 0.000 claims abstract description 185
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229960004555 rutoside Drugs 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
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235000011803 sesame oil Nutrition 0.000 description 1
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238000004904 shortening Methods 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
235000017281 sodium acetate Nutrition 0.000 description 1
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239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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239000001540 sodium lactate Substances 0.000 description 1
235000011088 sodium lactate Nutrition 0.000 description 1
229940005581 sodium lactate Drugs 0.000 description 1
NGSFWBMYFKHRBD-DKWTVANSSA-M sodium;(2s)-2-hydroxypropanoate Chemical compound [Na+].C[C@H](O)C([O-])=O NGSFWBMYFKHRBD-DKWTVANSSA-M 0.000 description 1
239000007921 spray Substances 0.000 description 1
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230000008733 trauma Effects 0.000 description 1
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235000019165 vitamin E Nutrition 0.000 description 1
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FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/605—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin to a 1-benzopyran-2-on (or the chalcones and hydrogenated chalcones thereof, e.g. coumermycin, novobiocin, novenamin)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01019—Cyclomaltodextrin glucanotransferase (2.4.1.19)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0102—Alpha-glucosidase (3.2.1.20)
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

KR1019910006864A 1990-04-29 1991-04-29 신규의 알파-글리코실 나린진 및 그 제조방법과 용도 KR100203759B1 (ko)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
KR1019990003921A KR100227598B1 (ko)	1990-04-29	1999-02-05	신규의α-글리코실나린진을함유시킨화장품

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP02-112665		1990-04-29
JP2112665A JP3060232B2 (ja)	1990-04-29	1990-04-29	α―グリコシルナリンジンとその製造方法並びに用途

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019990003921A Division KR100227598B1 (ko)	1990-04-29	1999-02-05	신규의α-글리코실나린진을함유시킨화장품

Publications (2)

Publication Number	Publication Date
KR910018400A KR910018400A (ko)	1991-11-30
KR100203759B1 true KR100203759B1 (ko)	1999-06-15

Family

ID=14592419

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019910006864A KR100203759B1 (ko)	1990-04-29	1991-04-29	신규의 알파-글리코실 나린진 및 그 제조방법과 용도

Country Status (6)

Country	Link
EP (1)	EP0455432B1 (ja)
JP (1)	JP3060232B2 (ja)
KR (1)	KR100203759B1 (ja)
AT (1)	ATE135362T1 (ja)
CA (1)	CA2041422A1 (ja)
DE (1)	DE69117795T2 (ja)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3321712B2 (ja)	1992-06-04	2002-09-09	株式会社林原生物化学研究所	マツエキス含有外用養毛剤
FR2719468B1 (fr) *	1994-05-05	1996-05-31	Oreal	Compositions cosmétiques à base de certains bioflavonoïdes et utilisations notamment dans le domaine capillaire.
US6224872B1 (en)	1997-07-31	2001-05-01	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Composition
KR20000019716A (ko) *	1998-09-15	2000-04-15	박호군	바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
WO2005087182A1 (ja)	2004-03-17	2005-09-22	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	機能性粉体
JP4982644B2 (ja) *	2004-08-23	2012-07-25	株式会社林原	α−グリコシルグリチルリチンを有効成分とする保湿剤とその用途
US9044038B2 (en) *	2007-11-12	2015-06-02	San-Ei Gen F.F.I., Inc.	Method of improving sweetness qualities of stevia extract
CN103833809A (zh) *	2014-01-21	2014-06-04	李玉山	柚皮苷的新型提取分离工艺
JP6503266B2 (ja) *	2015-08-31	2019-04-17	東洋精糖株式会社	水溶性組成物、その製造方法および難水溶性物質の溶解性改善方法
AU2017351069B2 (en) *	2016-10-24	2019-09-12	Colgate-Palmolive Company	Oral care compositions and methods of use
CA3070931A1 (en) *	2017-10-24	2019-05-02	Colgate-Palmolive Company	Personal care compositions including naringin:zinc complexes and methods for the same
EP3698642A1 (en) *	2019-02-21	2020-08-26	Interquim, S.A.	Flavonoids and animal health and performance
JPWO2021085293A1 (ja)	2019-10-30	2021-05-06
EP4108323A4 (en) *	2020-02-17	2024-03-13	Hayashibara Co	STABILIZER FOR EMULSION COMPOSITION
JP2023007737A (ja)	2021-07-02	2023-01-19	東洋精糖株式会社	ウイルスの細胞侵入阻害剤
WO2023090287A1 (ja) *	2021-11-16	2023-05-25	株式会社林原	塩味増強用組成物並びに口に入れる組成物及びその塩味を増強する方法
CN114868919A (zh) *	2022-05-07	2022-08-09	健码制药（广东）有限公司	一种清肝养肺的组合物及其加工方法
WO2024090424A1 (ja) *	2022-10-28	2024-05-02	株式会社林原	口当たり改善用組成物、飲食品組成物及びその製造方法、並びに口当たりを改善する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5432073A (en) *	1977-08-17	1979-03-09	Hitachi Ltd	Manufacture of cooling body
JPS5854799A (ja) *	1981-09-27	1983-03-31	Nitto Electric Ind Co Ltd	スピ−カ−キヤビネツト板材
FR2626583B1 (fr) *	1988-01-29	1991-03-15	Bioeurope	Procede de preparation enzymatique d'oligodextranes utiles dans la fabrication de substituts du sucre, et nouveaux oligodextranes
JPH01199575A (ja) *	1988-02-04	1989-08-10	Rikagaku Kenkyusho	新規なサイクロマルトデキストリン・グルカノトランスフェラーゼ及びその製造法
JP3194145B2 (ja) *	1989-09-28	2001-07-30	株式会社林原生物化学研究所	４Ｇ―α―Ｄ―グルコピラノシルルチンとその製造方法並びに用途

1990
- 1990-04-29 JP JP2112665A patent/JP3060232B2/ja not_active Expired - Fee Related
1991
- 1991-04-26 AT AT91303798T patent/ATE135362T1/de not_active IP Right Cessation
- 1991-04-26 EP EP91303798A patent/EP0455432B1/en not_active Expired - Lifetime
- 1991-04-26 DE DE69117795T patent/DE69117795T2/de not_active Expired - Fee Related
- 1991-04-29 KR KR1019910006864A patent/KR100203759B1/ko not_active IP Right Cessation
- 1991-04-29 CA CA002041422A patent/CA2041422A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ATE135362T1 (de)	1996-03-15
DE69117795T2 (de)	1996-10-02
EP0455432A1 (en)	1991-11-06
EP0455432B1 (en)	1996-03-13
DE69117795D1 (de)	1996-04-18
CA2041422A1 (en)	1991-10-30
KR910018400A (ko)	1991-11-30
JP3060232B2 (ja)	2000-07-10
JPH0413691A (ja)	1992-01-17

Legal Events

Date	Code	Title	Description
1996-04-25	A201	Request for examination
1998-08-27	E902	Notification of reason for refusal
1999-01-26	E902	Notification of reason for refusal
1999-02-05	A107	Divisional application of patent
1999-02-26	E701	Decision to grant or registration of patent right
1999-03-24	GRNT	Written decision to grant
2007-02-05	FPAY	Annual fee payment	Payment date: 20070205 Year of fee payment: 9
2008-03-25	LAPS	Lapse due to unpaid annual fee

Publication	Publication Date	Title
KR0184244B1 (ko)	1999-05-01	알파-글리코실헤스페리딘을함유시킨화장품
KR100228885B1 (ko)	1999-12-01	알파-글리코실 케르세틴과 그 제조방법 및 용도
KR0158454B1 (ko)	1998-11-16	알파-글리코실 루틴의 제조방법
KR100194270B1 (ko)	1999-06-15	알파-글리코실-엘-아스코르브산을 함유시킨 식품
KR0181013B1 (ko)	1999-10-01	결정질 2-오-알파-디-글루코피라노실-엘-아스코르브산을 함유시킨 화장품 조성물
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