JPS5951288A - 新規な９−ニトロカンプトテシン及びその製造法 - Google Patents

新規な９−ニトロカンプトテシン及びその製造法

Info

Publication number
JPS5951288A
JPS5951288A JP16094482A JP16094482A JPS5951288A JP S5951288 A JPS5951288 A JP S5951288A JP 16094482 A JP16094482 A JP 16094482A JP 16094482 A JP16094482 A JP 16094482A JP S5951288 A JPS5951288 A JP S5951288A
Authority
JP
Japan
Prior art keywords
camptothecin
nitrocamptothecin
chloroform
nitric acid
room temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16094482A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0312069B2 (de
Inventor
Sada Miyasaka
宮坂　貞
Seigo Sawada
誠吾 沢田
Kenichiro Nogata
野方　健一郎
Masahiko Mutai
務台　方彦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Priority to JP16094482A priority Critical patent/JPS5951288A/ja
Publication of JPS5951288A publication Critical patent/JPS5951288A/ja
Publication of JPH0312069B2 publication Critical patent/JPH0312069B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP16094482A 1982-09-17 1982-09-17 新規な９−ニトロカンプトテシン及びその製造法 Granted JPS5951288A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16094482A JPS5951288A (ja) 1982-09-17 1982-09-17 新規な９−ニトロカンプトテシン及びその製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16094482A JPS5951288A (ja) 1982-09-17 1982-09-17 新規な９−ニトロカンプトテシン及びその製造法

Publications (2)

Publication Number Publication Date
JPS5951288A true JPS5951288A (ja) 1984-03-24
JPH0312069B2 JPH0312069B2 (de) 1991-02-19

Family

ID=15725587

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16094482A Granted JPS5951288A (ja) 1982-09-17 1982-09-17 新規な９−ニトロカンプトテシン及びその製造法

Country Status (1)

Country Link
JP (1) JPS5951288A (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6315881U (de) * 1986-07-15 1988-02-02
US6166029A (en) * 1989-11-06 2000-12-26 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
CN1312155C (zh) * 2005-01-21 2007-04-25 华东理工大学 一种分离纯化9－硝基喜树碱的方法
CN100334089C (zh) * 2004-07-21 2007-08-29 王洋 一种9－硝基喜树碱的生产方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6315881U (de) * 1986-07-15 1988-02-02
JPH0319814Y2 (de) * 1986-07-15 1991-04-26
US6166029A (en) * 1989-11-06 2000-12-26 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
US6342506B1 (en) 1989-11-06 2002-01-29 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
US6624170B2 (en) 1989-11-06 2003-09-23 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble S-Camptothecin of the closed lactone ring form and derivatives thereof
CN100334089C (zh) * 2004-07-21 2007-08-29 王洋 一种9－硝基喜树碱的生产方法
CN1312155C (zh) * 2005-01-21 2007-04-25 华东理工大学 一种分离纯化9－硝基喜树碱的方法

Also Published As

Publication number Publication date
JPH0312069B2 (de) 1991-02-19

Similar Documents

Publication Publication Date Title
JPS5951289A (ja) 新規な９−置換−カンプトテシン誘導体
SK288073B6 (sk) Method of synthesizing campothecin-relating compounds
JPH0737460B2 (ja) ピラノインドリジン誘導体及びその製造法
JPS6232749B2 (de)
JPS5951287A (ja) 新規なカンプトテシン誘導体
JPS6345254A (ja) アルデヒト官能基を有するカルバゾ−ルおよびその製造方法
JPS6150985A (ja) 新規なカンプトテシン誘導体
JPS6185389A (ja) 新規なカンプトテシン誘導体
CN109516986B (zh) 2,4,4,8,8-五硝基-2-氮杂金刚烷及其合成方法
JPS5951288A (ja) 新規な９−ニトロカンプトテシン及びその製造法
JPH029032B2 (de)
JP7205059B2 (ja) エボジアミンの製造方法
CN111233750B (zh) 一种3,3-二氟-1,2,3,6-四氢哌啶类衍生物及其制备方法
JP5276267B2 (ja) Ｃｌ−２０のモノアミンおよびジアミン誘導体
RU2145325C1 (ru) Способы получения 9-аминокамптотецина, промежуточные продукты и способ их получения
CN107382898B (zh) 一种基于anpz含能母体结构的含能材料及其合成方法
JPS6332796B2 (de)
JP4498923B2 (ja) イミダゾ（１，２−ａ）ピリジン−３−アセトアミド類の調製方法
JPS58134095A (ja) 新規なカンプトテシン誘導体
CN113200902B (zh) 一种多取代吡咯衍生物及其制备方法
CN116283819A (zh) 一种异噻唑-5(2h)-亚胺类化合物的制备方法及其应用
JPH02264757A (ja) ニトロインドール類の製造方法
CN116621762A (zh) 一种3-硝基吲哚类似物及其制备方法
CN116606253A (zh) 基于吡唑环的碘代含能化合物及其制备方法与应用
Yue et al. Synthesis, Crystal Structure and Antitumor Activity of Novel 5-Chloro-β-carboline Derivatives