JP7221692B2 - 血栓溶解と薬剤送達のためのシステムおよび方法 - Google Patents
血栓溶解と薬剤送達のためのシステムおよび方法 Download PDFInfo
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
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- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
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- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
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- A61B2017/22079—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
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- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
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Description
供給ルーメンの遠位端に隣接し、吸引ルーメンの内部と流体連通するオリフィスであって、オリフィスは、吸引ルーメンの開放遠位端の近位に配置され、オリフィスは、加圧流体が供給ルーメンを通って圧送されると、スプレーパターンを生成するように構成される、オリフィスと、近位端、および遠位端を有する、マンドレルであって、遠位端は、90度よりも大きい湾曲を含み、かつ吸引カテーテルの遠位端と係合するように構成された凹部を含み、オリフィスは、マンドレルに印加された牽引力によって、吸引カテーテルの長手方向軸線に対して横断方向に平行移動可能な、マンドレルとを備える。
RU=VSCU/VICU
であり、VSCU=供給シリンダ252の使用可能な体積、およびVICU=注入シリンダ254の使用可能な体積である。
Claims (10)
- 血栓を吸引し薬剤を送達するためのシステムであって、
吸引ルーメンと、供給チューブとを含む吸引カテーテルであって、前記供給チューブが、近位端、遠位端、壁および供給ルーメンを有し、前記吸引ルーメンが、近位端、開放遠位端、および前記開放遠位端に隣接する内壁面を有する、吸引カテーテルと、
前記供給ルーメンの遠位端に隣接する位置にあり、前記吸引ルーメンと流体連通する少なくとも1つのオリフィスと
を備え、
前記少なくとも1つのオリフィスは、前記吸引ルーメンの前記開放遠位端の近位に配置され、前記少なくとも1つのオリフィスは、加圧流体が前記供給ルーメンを通って圧送されると、前記吸引ルーメンの長手方向軸線に対して垂直に導かれるスプレーパターンを生成するように構成され、前記吸引カテーテルの遠位端が水性環境に浸されると、前記スプレーパターンが前記吸引ルーメンの前記内壁面に衝突し、かつ前記内壁面に衝突したときの前記スプレーパターンが偏向されて、前記吸引ルーメンの前記開放遠位端から出るように構成された少なくとも略遠位方向を向いた流れに変換されるようになっており、
前記吸引ルーメンの内壁面は、少なくとも部分的に、前記略遠位方向を向いた流れを生成するように構成された、***した偏向エレメントを含み、
前記偏向エレメントは、区画線によって分離された2つの斜面を有し、
前記斜面は、前記吸引ルーメンの前記長手方向軸に対して、前記内壁面の半径を変化させる、システム。 - 前記遠位方向を向いた流れがジェットを含む、請求項1に記載のシステム。
- 前記スプレーパターンがジェットを含む、請求項1に記載のシステム。
- 前記スプレーパターンが少なくとも2つのジェットを含む、請求項1に記載のシステム。
- 前記少なくとも1つのオリフィスが、第1のオリフィスと、第2のオリフィスとを含み、前記第1のオリフィスが、前記少なくとも2つのジェットのうちの第1のジェットを生成するように構成され、前記第2のオリフィスが、前記少なくとも2つのジェットのうちの第2のジェットを生成するように構成され、前記内壁面に衝突する、前記第1のジェットおよび前記第2のジェットのうちの少なくとも1つが、前記略遠位方向を向いた流れに変換されるようになっている、請求項4に記載のシステム。
- 前記偏向エレメントが、少なくとも部分的に、略近位方向を向いた流れを生成するように構成されている、請求項1に記載のシステム。
- 前記偏向エレメントが、前記内壁面に衝突する前記スプレーパターンの概ね全てを、前記略遠位方向を向いた流れに変換するように構成されている、請求項1に記載のシステム。
- 前記供給ルーメンが、溶解剤、または造影剤のうちの少なくとも1つを輸送するように構成されている、請求項1に記載のシステム。
- 前記供給チューブが前記吸引ルーメン内で延びている、請求項1に記載のシステム。
- 前記偏向エレメントが、前記吸引カテーテルの細長いシャフトの内壁に固定されている、請求項1に記載のシステム。
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JP2022193291A JP2023022249A (ja) | 2016-04-06 | 2022-12-02 | 血栓溶解と薬剤送達のためのシステムおよび方法 |
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US201662318972P | 2016-04-06 | 2016-04-06 | |
US62/318,972 | 2016-04-06 | ||
US15/480,354 US10492805B2 (en) | 2016-04-06 | 2017-04-05 | Systems and methods for thrombolysis and delivery of an agent |
US15/480,354 | 2017-04-05 | ||
PCT/US2017/026383 WO2017177022A1 (en) | 2016-04-06 | 2017-04-06 | Systems and methods for thrombolysis and delivery of an agent |
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JP2019513452A JP2019513452A (ja) | 2019-05-30 |
JP2019513452A5 JP2019513452A5 (ja) | 2020-05-14 |
JP7221692B2 true JP7221692B2 (ja) | 2023-02-14 |
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JP2022193291A Pending JP2023022249A (ja) | 2016-04-06 | 2022-12-02 | 血栓溶解と薬剤送達のためのシステムおよび方法 |
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US (7) | US10492805B2 (ja) |
EP (2) | EP4144310A1 (ja) |
JP (2) | JP7221692B2 (ja) |
CN (1) | CN109152583B (ja) |
CA (1) | CA3019166A1 (ja) |
WO (1) | WO2017177022A1 (ja) |
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