JP5148478B2 - マラリア治療用のフェロキンとアーテミシニン誘導体との組合せ - Google Patents

マラリア治療用のフェロキンとアーテミシニン誘導体との組合せ Download PDF

Info

Publication number
JP5148478B2
JP5148478B2 JP2008507122A JP2008507122A JP5148478B2 JP 5148478 B2 JP5148478 B2 JP 5148478B2 JP 2008507122 A JP2008507122 A JP 2008507122A JP 2008507122 A JP2008507122 A JP 2008507122A JP 5148478 B2 JP5148478 B2 JP 5148478B2
Authority
JP
Japan
Prior art keywords
ferrokin
pharmaceutical composition
composition according
day
artesunate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008507122A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008536900A (ja
Inventor
フレス，ローラン
テール−ミナシアン，ダニエル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of JP2008536900A publication Critical patent/JP2008536900A/ja
Application granted granted Critical
Publication of JP5148478B2 publication Critical patent/JP5148478B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008507122A 2005-04-20 2006-04-18 マラリア治療用のフェロキンとアーテミシニン誘導体との組合せ Expired - Fee Related JP5148478B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0503932A FR2884715B1 (fr) 2005-04-20 2005-04-20 Association entre la ferroquine et un derive d'artemisinine pour le traitement du paludisme
FR0503932 2005-04-20
PCT/FR2006/000842 WO2006111647A1 (fr) 2005-04-20 2006-04-18 Association entre la ferroquine et un derive d’artemisinine pour le traitement du paludisme

Publications (2)

Publication Number Publication Date
JP2008536900A JP2008536900A (ja) 2008-09-11
JP5148478B2 true JP5148478B2 (ja) 2013-02-20

Family

ID=35385843

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008507122A Expired - Fee Related JP5148478B2 (ja) 2005-04-20 2006-04-18 マラリア治療用のフェロキンとアーテミシニン誘導体との組合せ

Country Status (30)

Country Link
US (1) US20120258945A1 (no)
EP (1) EP1874293A1 (no)
JP (1) JP5148478B2 (no)
KR (1) KR20080009088A (no)
CN (2) CN101163470A (no)
AP (1) AP2782A (no)
AR (1) AR054253A1 (no)
AU (1) AU2006238506B2 (no)
BR (1) BRPI0610851A2 (no)
CA (1) CA2605385A1 (no)
CR (1) CR9425A (no)
DO (1) DOP2006000092A (no)
EA (1) EA012630B1 (no)
FR (1) FR2884715B1 (no)
GT (1) GT200600157A (no)
HN (1) HN2006015130A (no)
IL (1) IL186048A0 (no)
MA (1) MA29451B1 (no)
MX (1) MX2007012645A (no)
MY (1) MY145581A (no)
NO (1) NO20075920L (no)
NZ (1) NZ562117A (no)
PA (1) PA8669801A1 (no)
PE (2) PE20061314A1 (no)
SG (1) SG161270A1 (no)
TN (1) TNSN07359A1 (no)
TW (1) TWI387456B (no)
UA (1) UA96414C2 (no)
WO (1) WO2006111647A1 (no)
ZA (1) ZA200708800B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2926993B1 (fr) * 2008-02-06 2011-03-11 Sanofi Aventis Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme
FR2952823B1 (fr) * 2009-10-30 2012-04-20 Sanofi Aventis Utilisation de la ferroquine dans le traitement ou la prevention du paludisme
FR2951945B1 (fr) * 2009-11-05 2013-08-09 Sanofi Aventis Composition pharmaceutique
FR2961209B1 (fr) * 2010-06-11 2013-03-01 Sanofi Aventis Procede de synthese de la ferroquine par amination reductrice convergente.
FR2989588A1 (fr) * 2012-04-19 2013-10-25 Centre Nat Rech Scient Composes pour la prevention ou le traitement des infections par des virus de la famille des flaviviridae
WO2015069942A1 (en) 2013-11-08 2015-05-14 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
CN105250295B (zh) * 2014-07-07 2018-12-25 广州中医药大学科技产业园有限公司 一种联合用药物及其作为免疫调节剂的应用
WO2017015344A1 (en) * 2015-07-20 2017-01-26 University Of Vermont And State Agricultural College Use of cymanquine compounds as antimalarial agents
CN107802755A (zh) * 2017-11-08 2018-03-16 江西龙卿堂科技有限公司 一种具有防蚊防疟作用的青蒿软膏
KR102073961B1 (ko) * 2018-11-16 2020-02-05 (주)프론트바이오 메트포르민 및 페로센계 화합물을 유효성분으로 함유하는 암 예방 또는 치료용 약학적 조성물
WO2022231238A1 (ko) * 2021-04-26 2022-11-03 심민보 아르테수네이트 또는 그의 염, 및 피로나리딘 또는 그의 염의 해열, 항염증, 항바이러스용, 또는 covid-19 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법
CN113952360B (zh) * 2021-09-14 2023-03-10 上海交通大学 一种亚铁离子在治疗疟疾的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166154B (no) * 1987-05-08 1990-03-24 Hoechst India
WO2005023304A2 (en) * 2003-09-04 2005-03-17 Cipla Limited Antimalarial compositions and manufacturing process thereof

Also Published As

Publication number Publication date
BRPI0610851A2 (pt) 2010-08-03
EP1874293A1 (fr) 2008-01-09
DOP2006000092A (es) 2006-11-15
CR9425A (es) 2008-02-20
AU2006238506B2 (en) 2012-03-01
PE20061314A1 (es) 2006-12-27
TNSN07359A1 (en) 2008-12-31
AU2006238506A1 (en) 2006-10-26
HN2006015130A (es) 2010-08-19
PE20110119A1 (es) 2011-03-08
NO20075920L (no) 2007-11-16
ZA200708800B (en) 2009-01-28
MY145581A (en) 2012-02-29
CA2605385A1 (fr) 2006-10-26
JP2008536900A (ja) 2008-09-11
PA8669801A1 (es) 2006-11-09
AP2782A (en) 2013-10-31
MA29451B1 (fr) 2008-05-02
FR2884715A1 (fr) 2006-10-27
EA012630B1 (ru) 2009-10-30
EA200702282A1 (ru) 2008-02-28
NZ562117A (en) 2010-01-29
AR054253A1 (es) 2007-06-13
UA96414C2 (ru) 2011-11-10
FR2884715B1 (fr) 2007-06-15
KR20080009088A (ko) 2008-01-24
US20120258945A1 (en) 2012-10-11
MX2007012645A (es) 2007-12-13
CN101163470A (zh) 2008-04-16
TWI387456B (zh) 2013-03-01
AP2007004211A0 (en) 2007-10-31
TW200716092A (en) 2007-05-01
WO2006111647A1 (fr) 2006-10-26
SG161270A1 (en) 2010-05-27
CN102836163A (zh) 2012-12-26
GT200600157A (es) 2006-11-07
IL186048A0 (en) 2008-02-09

Similar Documents

Publication Publication Date Title
JP5148478B2 (ja) マラリア治療用のフェロキンとアーテミシニン誘導体との組合せ
Warrell et al. Treatment and prevention of malaria
KR100221689B1 (ko) 항말라리아조성물
US5219865A (en) Pharmaceutical combination for the prophylaxis and therapy of malaria
KR20080081358A (ko) Ｈｉｖ 인테그라제 억제제의 약동학을 개선하기 위한 방법
WO2012171015A2 (en) Therapeutic combination for cancer treatment
AU614515B2 (en) A pharmaceutical combination for the prophylaxis and therapy of malaria
JP5469095B2 (ja) 急性マラリアを治療するためのビス−チアゾリウム塩またはこれらの前駆体およびアルテミシニンまたはこれらの誘導体の組み合わせ
JPS6256425A (ja) マラリア治療用の組合せ製剤
JP7391036B2 (ja) キノリン－４－カルボキサミドおよびベンゾナフチリジン誘導体の抗マラリア複合薬としての組み合わせ。
JP2001507672A (ja) Ｃｉｓ―縮合シクロペンテノ―１，２，４―トリオキサン誘導体を含有する抗マラリア組成物
WO2017143964A1 (zh) Quisinostat，一种新型的高效抗疟药物
JP2002540150A (ja) ウイルス治療
JP5820812B2 (ja) マラリアの治療または予防におけるフェロキンの使用
WO1992007564A2 (en) Method of treating demyelinating disease
JP2011037814A (ja) マラリア原虫疾患予防又は治療用の５−ヘテロ環置換イミノ−９−ジアルキルアミノベンゾ［ａ］フェノキサチン化合物又はその塩とアーテミシニン誘導体との組み合わせ
JP2010138081A (ja) インフルエンザウイルス免疫賦活剤、および抗インフルエンザウイルス剤
JPH0873355A (ja) 抗マラリア薬耐性克服剤
KR100930480B1 (ko) 신규 디아릴 헵타노이드계 화합물 및 그 용도
JPH04230322A (ja) 抗マラリア医薬組成物

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090331

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120313

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120607

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120614

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120730

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120821

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121031

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20121114

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121120

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121128

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151207

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees