JP4808363B2 - 新規ポリペプチド及びこれを含む抗hiv剤 - Google Patents

新規ポリペプチド及びこれを含む抗hiv剤 Download PDF

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Publication number
JP4808363B2
JP4808363B2 JP2002525180A JP2002525180A JP4808363B2 JP 4808363 B2 JP4808363 B2 JP 4808363B2 JP 2002525180 A JP2002525180 A JP 2002525180A JP 2002525180 A JP2002525180 A JP 2002525180A JP 4808363 B2 JP4808363 B2 JP 4808363B2
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residue
polypeptide
citrulline
alanine
arginine
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Japanese (ja)
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JPWO2002020561A1 (ja
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信孝 藤井
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バイオカイン セラピューティックス リミテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855Proteins from animals other than mammals or birds
    • Y10S530/857Fish; fish eggs; shell fish; crustacea

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2002525180A 2000-09-05 2001-09-05 新規ポリペプチド及びこれを含む抗hiv剤 Expired - Fee Related JP4808363B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002525180A JP4808363B2 (ja) 2000-09-05 2001-09-05 新規ポリペプチド及びこれを含む抗hiv剤

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2000269296 2000-09-05
JP2000269296 2000-09-05
JP2001092306 2001-03-28
JP2001092306 2001-03-28
JP2002525180A JP4808363B2 (ja) 2000-09-05 2001-09-05 新規ポリペプチド及びこれを含む抗hiv剤
PCT/JP2001/007668 WO2002020561A1 (fr) 2000-09-05 2001-09-05 Nouveaux polypeptides et medicaments anti-vih contenant lesdits polypeptides

Publications (2)

Publication Number Publication Date
JPWO2002020561A1 JPWO2002020561A1 (ja) 2004-01-15
JP4808363B2 true JP4808363B2 (ja) 2011-11-02

Family

ID=26599311

Family Applications (1)

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JP2002525180A Expired - Fee Related JP4808363B2 (ja) 2000-09-05 2001-09-05 新規ポリペプチド及びこれを含む抗hiv剤

Country Status (8)

Country Link
US (2) US7138488B2 (fr)
EP (1) EP1323730B1 (fr)
JP (1) JP4808363B2 (fr)
AT (1) ATE465170T1 (fr)
AU (1) AU2001284419A1 (fr)
CA (1) CA2421183C (fr)
DE (1) DE60136373D1 (fr)
WO (1) WO2002020561A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
JP4781621B2 (ja) * 2002-08-27 2011-09-28 バイオカイン セラピューティックス リミテッド Cxcr4拮抗薬およびその用途
AU2003261723A1 (en) * 2002-08-27 2004-03-19 Takeda Chemical Industries, Ltd. Cxcr4 antagonist and use thereof
WO2006126188A2 (fr) * 2005-05-25 2006-11-30 Hadasit Medical Research Services And Development Ltd. Antagonistes de cxcr4 pour la cicatrisation des blessures et la reepithelialisation
ES2842210T3 (es) * 2006-12-21 2021-07-13 Biokine Therapeutics Ltd 4F-benzoil-TN14003 para la movilización de células progenitoras hematopoyéticas con vistas al trasplante
JP5715622B2 (ja) 2009-06-14 2015-05-07 バイオカイン セラピューティックス リミテッド 血小板レベルを増大させるためのペプチド療法
US20130303460A1 (en) 2011-01-10 2013-11-14 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
KR20150135432A (ko) 2013-03-24 2015-12-02 바이오카인 테라퓨틱스 리미티드 골수성 백혈병의 치료 방법
US20160243187A1 (en) 2013-10-31 2016-08-25 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
US20170042893A1 (en) 2014-02-03 2017-02-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Use of casein kinase i inhibitors for depleting stem cells
EP3943098A3 (fr) 2015-07-16 2022-05-11 Biokine Therapeutics Ltd. Compositions et procédés pour le traitement du cancer
US20180221393A1 (en) 2015-08-03 2018-08-09 Biokine Therapeutics Ltd. Cxcr4 binding agents for treatment of diseases
CA3014530A1 (fr) 2016-02-23 2017-08-31 Biolinerx Ltd. Methodes de traitement de la leucemie myeloide aigue
EP3856225A1 (fr) 2018-09-25 2021-08-04 BioLineRx Ltd. Procédés de sélection d'un traitement contre un cancer associé aux récepteurs cxcr4
CN116802189A (zh) 2020-12-30 2023-09-22 百欧林纳克斯有限公司 制备肽的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69416824T2 (de) 1993-10-14 1999-07-08 Seikagaku Corp., Tokio/Tokyo Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen
AU762472B2 (en) 1998-03-13 2003-06-26 University Of British Columbia, The Therapeutic chemokine receptor antagonists
AU2001236065A1 (en) * 2000-03-03 2001-09-12 Nobutaka Fujii Antiviral compounds
AU2003261723A1 (en) * 2002-08-27 2004-03-19 Takeda Chemical Industries, Ltd. Cxcr4 antagonist and use thereof

Also Published As

Publication number Publication date
US7138488B2 (en) 2006-11-21
EP1323730A1 (fr) 2003-07-02
US20060264605A1 (en) 2006-11-23
EP1323730B1 (fr) 2010-04-21
AU2001284419A1 (en) 2002-03-22
EP1323730A4 (fr) 2005-01-05
DE60136373D1 (de) 2008-12-11
ATE465170T1 (de) 2010-05-15
US7595298B2 (en) 2009-09-29
CA2421183C (fr) 2015-06-16
WO2002020561A1 (fr) 2002-03-14
CA2421183A1 (fr) 2003-03-04
US20040116655A1 (en) 2004-06-17
JPWO2002020561A1 (ja) 2004-01-15

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