JP4808363B2 - 新規ポリペプチド及びこれを含む抗hiv剤 - Google Patents
新規ポリペプチド及びこれを含む抗hiv剤 Download PDFInfo
- Publication number
- JP4808363B2 JP4808363B2 JP2002525180A JP2002525180A JP4808363B2 JP 4808363 B2 JP4808363 B2 JP 4808363B2 JP 2002525180 A JP2002525180 A JP 2002525180A JP 2002525180 A JP2002525180 A JP 2002525180A JP 4808363 B2 JP4808363 B2 JP 4808363B2
- Authority
- JP
- Japan
- Prior art keywords
- residue
- polypeptide
- citrulline
- alanine
- arginine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
- Y10S530/857—Fish; fish eggs; shell fish; crustacea
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Insects & Arthropods (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002525180A JP4808363B2 (ja) | 2000-09-05 | 2001-09-05 | 新規ポリペプチド及びこれを含む抗hiv剤 |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000269296 | 2000-09-05 | ||
JP2000269296 | 2000-09-05 | ||
JP2001092306 | 2001-03-28 | ||
JP2001092306 | 2001-03-28 | ||
JP2002525180A JP4808363B2 (ja) | 2000-09-05 | 2001-09-05 | 新規ポリペプチド及びこれを含む抗hiv剤 |
PCT/JP2001/007668 WO2002020561A1 (fr) | 2000-09-05 | 2001-09-05 | Nouveaux polypeptides et medicaments anti-vih contenant lesdits polypeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
JPWO2002020561A1 JPWO2002020561A1 (ja) | 2004-01-15 |
JP4808363B2 true JP4808363B2 (ja) | 2011-11-02 |
Family
ID=26599311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002525180A Expired - Fee Related JP4808363B2 (ja) | 2000-09-05 | 2001-09-05 | 新規ポリペプチド及びこれを含む抗hiv剤 |
Country Status (8)
Country | Link |
---|---|
US (2) | US7138488B2 (fr) |
EP (1) | EP1323730B1 (fr) |
JP (1) | JP4808363B2 (fr) |
AT (1) | ATE465170T1 (fr) |
AU (1) | AU2001284419A1 (fr) |
CA (1) | CA2421183C (fr) |
DE (1) | DE60136373D1 (fr) |
WO (1) | WO2002020561A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8435939B2 (en) | 2000-09-05 | 2013-05-07 | Biokine Therapeutics Ltd. | Polypeptide anti-HIV agent containing the same |
JP4781621B2 (ja) * | 2002-08-27 | 2011-09-28 | バイオカイン セラピューティックス リミテッド | Cxcr4拮抗薬およびその用途 |
AU2003261723A1 (en) * | 2002-08-27 | 2004-03-19 | Takeda Chemical Industries, Ltd. | Cxcr4 antagonist and use thereof |
WO2006126188A2 (fr) * | 2005-05-25 | 2006-11-30 | Hadasit Medical Research Services And Development Ltd. | Antagonistes de cxcr4 pour la cicatrisation des blessures et la reepithelialisation |
ES2842210T3 (es) * | 2006-12-21 | 2021-07-13 | Biokine Therapeutics Ltd | 4F-benzoil-TN14003 para la movilización de células progenitoras hematopoyéticas con vistas al trasplante |
JP5715622B2 (ja) | 2009-06-14 | 2015-05-07 | バイオカイン セラピューティックス リミテッド | 血小板レベルを増大させるためのペプチド療法 |
US20130303460A1 (en) | 2011-01-10 | 2013-11-14 | Biokine Therapeutics Ltd. | Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma |
US9439942B2 (en) | 2012-04-24 | 2016-09-13 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
KR20150135432A (ko) | 2013-03-24 | 2015-12-02 | 바이오카인 테라퓨틱스 리미티드 | 골수성 백혈병의 치료 방법 |
US20160243187A1 (en) | 2013-10-31 | 2016-08-25 | Biokine Therapeutics Ltd. | Methods of treating acute myeloid leukemia with a flt3 mutation |
US20170042893A1 (en) | 2014-02-03 | 2017-02-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Use of casein kinase i inhibitors for depleting stem cells |
EP3943098A3 (fr) | 2015-07-16 | 2022-05-11 | Biokine Therapeutics Ltd. | Compositions et procédés pour le traitement du cancer |
US20180221393A1 (en) | 2015-08-03 | 2018-08-09 | Biokine Therapeutics Ltd. | Cxcr4 binding agents for treatment of diseases |
CA3014530A1 (fr) | 2016-02-23 | 2017-08-31 | Biolinerx Ltd. | Methodes de traitement de la leucemie myeloide aigue |
EP3856225A1 (fr) | 2018-09-25 | 2021-08-04 | BioLineRx Ltd. | Procédés de sélection d'un traitement contre un cancer associé aux récepteurs cxcr4 |
CN116802189A (zh) | 2020-12-30 | 2023-09-22 | 百欧林纳克斯有限公司 | 制备肽的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69416824T2 (de) | 1993-10-14 | 1999-07-08 | Seikagaku Corp., Tokio/Tokyo | Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen |
AU762472B2 (en) | 1998-03-13 | 2003-06-26 | University Of British Columbia, The | Therapeutic chemokine receptor antagonists |
AU2001236065A1 (en) * | 2000-03-03 | 2001-09-12 | Nobutaka Fujii | Antiviral compounds |
AU2003261723A1 (en) * | 2002-08-27 | 2004-03-19 | Takeda Chemical Industries, Ltd. | Cxcr4 antagonist and use thereof |
-
2001
- 2001-09-05 US US10/363,209 patent/US7138488B2/en not_active Expired - Lifetime
- 2001-09-05 WO PCT/JP2001/007668 patent/WO2002020561A1/fr active Application Filing
- 2001-09-05 JP JP2002525180A patent/JP4808363B2/ja not_active Expired - Fee Related
- 2001-09-05 AU AU2001284419A patent/AU2001284419A1/en not_active Abandoned
- 2001-09-05 CA CA2421183A patent/CA2421183C/fr not_active Expired - Lifetime
- 2001-09-05 DE DE60136373T patent/DE60136373D1/de not_active Expired - Lifetime
- 2001-09-05 AT AT01963414T patent/ATE465170T1/de not_active IP Right Cessation
- 2001-09-05 EP EP01963414A patent/EP1323730B1/fr not_active Expired - Lifetime
-
2006
- 2006-08-01 US US11/497,225 patent/US7595298B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7138488B2 (en) | 2006-11-21 |
EP1323730A1 (fr) | 2003-07-02 |
US20060264605A1 (en) | 2006-11-23 |
EP1323730B1 (fr) | 2010-04-21 |
AU2001284419A1 (en) | 2002-03-22 |
EP1323730A4 (fr) | 2005-01-05 |
DE60136373D1 (de) | 2008-12-11 |
ATE465170T1 (de) | 2010-05-15 |
US7595298B2 (en) | 2009-09-29 |
CA2421183C (fr) | 2015-06-16 |
WO2002020561A1 (fr) | 2002-03-14 |
CA2421183A1 (fr) | 2003-03-04 |
US20040116655A1 (en) | 2004-06-17 |
JPWO2002020561A1 (ja) | 2004-01-15 |
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