JP4635276B2 - 生体組織における欠損を治療するための装置および方法 - Google Patents
生体組織における欠損を治療するための装置および方法 Download PDFInfo
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- JP4635276B2 JP4635276B2 JP2005503939A JP2005503939A JP4635276B2 JP 4635276 B2 JP4635276 B2 JP 4635276B2 JP 2005503939 A JP2005503939 A JP 2005503939A JP 2005503939 A JP2005503939 A JP 2005503939A JP 4635276 B2 JP4635276 B2 JP 4635276B2
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- implant
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0085—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof hardenable in situ, e.g. epoxy resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0067—Three-dimensional shapes conical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0018—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0023—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in porosity
-
- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
- A61F2310/00383—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Cell Biology (AREA)
- Materials Engineering (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
Description
脂肪族ポリエステル
セルロース
キチン
コラーゲン
グリコリド共重合体
ラクチド共重合体
エラスチン
フィブリン
グリコリド/l−ラクチド共重合体(PGA/PLLA)
グリコリド/トリメチレン炭酸塩共重合体(PGA/TMC)
ヒドロゲル
ラクチド/テトラメチルグリコリド共重合体
ラクチド/トリメチレンカーボネート共重合体
ラクチド/ε−カプロラクトン共重合体
ラクチド/σ−バレロラクトン共重合体
L-ラクチド/dl−ラクチド共重合体
メチルメタクリレート―N―ビニルピロリドン共重合体
変性タンパク質
ナイロン−2
PHBA/γ−ヒドロキシバレレート共重合体
PLA/酸化ポリエチレン共重合体
PLA/酸化ポリエチレン(PELA)
ポリ(アミノ酸)
ポリ(炭酸トリメチレン)
ポリヒドロキシ脂肪酸ポリマー(PHA)
ポリ(シュウ酸アルキレン)
ポリ(ジグリコール酸ブチレン)
ポリ(ヒドロキシ酪酸)(PHB)
ポリ(n−ビニルピロリドン)
ポリ(オルトエステル)
2−シアノアクリル酸ポリアルキル
ポリ無水物
ポリシアノアクリル酸
ポリデプシペプチド
ポリジヒドロピラン
ポリ−dl−ラクチド(PDLLA)
ポリエステルアミド
シュウ酸ポリエステル
ポリグリコリド(PGA)
ポリイミノ炭酸塩
ポリラクチド(PLA)
ポリ―1―ラクチド(PLA)
ポリオルトエステル
ポリ―p―ジオキサノン(PDO)
ポリペプチド
ポリホスファゼン
多糖類
ポリウレタン(PU)
ポリビニルアルコール(PVA)
ポリ―β―ヒドロキシプロピオン酸(PHPA)
ポリ―β―ヒドロキシ酪酸エステル(PBA)
ポリ―σ―バレロラクトン
ポリ―β―カルボン酸
ポリ―β―リンゴ酸(PMLA)
ポリ−ε−カプロラクトン(PCL)
擬(Pseudo)ポリ(アミノ酸)
デンプン
炭酸トリメチレン(TMC)
チロシンベースのポリマー
遺伝物質を有する、または有していないアデノウィルス
血管形成薬
アンジオテンシン転換酵素阻害薬(ACE阻害薬)
アンジオテンシンIIアンタゴニスト
抗血管形成薬
抗不整脈薬
抗菌薬
抗生物質
エリスロマイシン
ペニシリン
抗凝固薬
ヘパリン
抗成長因子
抗炎症薬
デキサメタゾン
アスピリン
ヒドロコルチゾン
抗酸化薬
抗血小板薬
フォルスコリン
抗増殖薬
抗拒絶反応薬
ラパマイシン
抗再狭窄薬
アンチセンス
抗血栓形成薬
アルガトロバン
ヒルジン
GPIIb/IIIa阻害薬
抗ウィルス薬
動脈形成薬
酸性繊維芽細胞成長因子(aFGF)
アンギオジェニン
アンギオトロピン
塩基性繊維芽細胞成長因子(bFGF)
骨形態形成タンパク質(BMP)
上皮成長因子(EGF)
フィブリン
顆粒球マクロファージコロニー刺激因子(GM−CSF)
肝細胞成長因子(HGF)
HIF−1
インスリン成長因子(IGF−1)
インターロイキン−8(IL−8)
MAC−1
ニコチンアミド
血小板由来内皮細胞成長因子(PD−ECGF)
血小板由来成長因子(PDGF)
トランスフォーミング成長因子αおよびβ(TGF−α、TGF−β)
腫瘍壊死因子α(TNF−α)
血管内皮成長因子(VEGF)
血管透過性因子(VPF)
バクテリア
β遮断薬
血液凝固因子
骨形態形成タンパク質(BMP)
カルシウムチャネル遮断薬
発ガン物質
細胞
骨髄細胞
血液細胞
幹細胞
臍帯細胞
脂肪細胞
骨細胞
軟骨細胞
化学療法薬(例えば、セラミド、タキソール、シスプラチン)
コレステロール減少薬
コンドロイチン
コラーゲン阻害薬
コロニー刺激因子
クマジン
サイトカインプロスタグランジン
象牙質
エトレチナート
遺伝物質
グルコサミン
グルコサミノグリカン
GPIIb/IIIa阻害薬
L−703,081
顆粒球コロニー刺激因子(GM−CSF)
成長因子アンタゴニストまたは阻害薬
成長因子
酸性繊維芽細胞成長因子(aFGF)
自己由来成長因子
塩基性繊維芽細胞成長因子(bFGF)
骨形態形成タンパク質(BMPs)
ブタ由来成長因子
軟骨由来成長因子(CDF)
上皮細胞成長因子(ECGF)
上皮成長因子(EGF)
繊維芽細胞成長因子(FGF)
肝細胞成長因子(HGF)
インスリン様成長因子(例えば、IGF−I)
神経成長因子(NGF)
血小板由来内皮細胞成長因子(PD−ECGF)
血小板由来成長因子(PDGF)
組み換えNGF(rhNGF)
組み換え成長因子
組織由来サイトカイン
組織壊死因子(TNF)
トランスフォーミング成長因子α(TGF−α)
トランスフォーミング成長因子β(TGF−β)
組織壊死因子α(TNF−α)
血管内皮成長因子(VEGF)
血管透過性因子(UPF)
成長ホルモン
ヘパリン硫酸塩プロテオグリカン
HMC−CoA還元酵素阻害薬(スタチン)
ホルモン
エリスロポイエチン
immoxidal
免疫抑制薬
炎症伝達物質
インスリン
インターロイキン
インターリューキン−8(IL−8)
インターリューキン
脂肪減少薬
リポタンパク質
低分子量ヘパリン
リンパ球
リシン
MAC−1
モルフォゲン
一酸化窒素(NO)
ヌクレオチド
ペプチド
PR39
タンパク質
プロスタグランジン
プロテオグリカン
パールカン
放射性物質
ヨウ素−125
ヨウ素−131
イリジウム−192
パラジウム−103
放射性医薬品
二次伝達物質
セラミド
ソマトメジン
スタチン
ステロイド
スルホニル
トロンビン
トロンビン阻害薬
血栓溶解薬
チクリド
チロシンキナーゼ阻害薬
ST638
AG−17
血管拡張薬
ヒスタミン
フォースコリン
ニトログリセリン
ビタミン
E
C
酵母
脂肪細胞
血液細胞
骨髄
改変された受容体または結合部位を有する細胞
内皮細胞
上皮細胞
繊維芽細胞
遺伝子組み換え細胞
糖タンパク質
成長因子
脂質
リポソーム
マクロファージ
間葉幹細胞
前駆細胞
赤血球
骨格筋細胞
平滑筋細胞
幹細胞
小胞
アルギン酸塩
カルシウム
リン酸カルシウム
硫酸カルシウム
セラミック
キトサン
シアノアクリル酸塩
コラーゲン
ダクロン
脱塩した骨
エラスチン
フィブリン
ゼラチン
ガラス
金
ヒアルロン酸
ヒドロゲル
水酸化アパタイト
メタクリル酸ヒドロキシエチル
ヒアルロン酸
リポソーム
間葉細胞
ニチノール
骨芽細胞
酸化還元型セルロース
リン酸塩ガラス
ポリエチレングリコール
ポリエステル
多糖類
ポリビニルアルコール
血小板、血液細胞
放射線不透過剤(Radiopacifiers)
塩
シリコン
絹
スチール(例えば、ステンレススチール)
合成ポリマー
トロンビン
チタン
1,2−シクロヘキサジオン
クエン酸アセトキシトリエチル
アセチル化ヤシ油(EPZ)
クエン酸アセチルトリ−n−ブチル
クエン酸アセチルトリ−n−ヘキシル
クエン酸アセチルトリエチル
アジピン酸エステル
安息香酸−2−ヒドロキシアセテート
フタル酸ビス−2−メトキシエチル
ステアリル酸カルシウム
ショウノウ
カプロラクトン
クエン酸エステル
フタル酸ジブチル
フタル酸ジエチル
アジピン酸ジオクチル
エポキシ化大豆油
安息香酸エチル
アセチル化クエン酸のエチル、ブチル、およびヘキシルエステル
エチル基で終了した乳酸オリゴマー
グリセロール
トリ酢酸グリセリル
グリコリド
ヘキサメチルベンゼン
ラクチド
アマニ油
脂質
リポソーム
クエン酸n−ブチルトリ−n−ヘキシル
オイル
フタル酸エステル
ポリウレタン
ステアリル酸
クエン酸トリブチル
クエン酸トリエチル
シリカ
クレイ
金属
酸化アルミニウム
セラミック
ポリマー
酸化金属
アルブミン
アルキルメタクリレート
グリコサミノグリカン
ヘパリン
ヒアルロン酸
吸収性ポリマー
インテグリン
パリレン
ホスホリルコリン
リン脂質
ポリアクリルアミド
ポリ無水物
酢酸ポリエチレン
ポリエチレングリコール
酸化ポリエチレン
ポリペプチド
ポリウレタン
ポリビニルアルコール
ポリビニルピロリドン
シラン
シリコン
骨
骨組織採取術
脊椎固定術
脊椎固定/融合術
截骨術
骨の生体組織検査
顎顔面再構築
長骨固定術
圧迫骨折
股間接の再構築/置換術
膝間接の再構築/置換術
手部の再構築
足部の再構築
踝関節の再構築
手関節の再構築
肘関節の再構築
肩部の再構築
軟骨
自家骨軟骨移植術
半月版
歯骨
歯槽堤増大形成術
第三大臼歯抜歯
腱
じん帯
皮膚
局所的創傷
火傷治療
生体組織検査
筋肉
硬膜
肺
肝臓
すい臓
胆のう
腎臓
神経
動脈
バイパス手術
心臓カテーテル検査
心臓
心臓弁置換法
Claims (11)
- 少なくとも生体組織内に配置される時に、骨伝導性マトリックスを備え、前記マトリックスの少なくとも一部分が自然の不溶性コラーゲンをコラーゲン繊維の形態で備えており、前記生体組織内に配置される、前記生体組織を修復または再生するためのインプラント。
- 前記マトリックスがさらに孔を備え、前記孔は少なくとも一つの骨誘導性因子を収容し、前記骨誘導性因子は少なくとも一つの治療薬を備えている、請求項1に記載のインプラント。
- 前記マトリックスが少なくとも一つの治療薬をさらに備えている、請求項1に記載のインプラント。
- 前記治療薬が、少なくとも一つの薬物または生物学的に活性な作用物質を備えている、請求項3に記載のインプラント。
- 前記マトリックスが少なくとも一つのセラミックをさらに備えている、請求項1に記載のインプラント。
- 前記セラミックは、リン酸カルシウム、硫酸カルシウムまたは水酸化アパタイトを含む、請求項5に記載のインプラント。
- 前記マトリックスが生体マッチングされている、請求項1に記載のインプラント。
- 前記マトリックスが圧縮された状態にある、請求項1に記載のインプラント。
- 前記圧縮された状態からの弾性回復が、欠損部位への放出後に起こる、請求項8に記載のインプラント。
- 前記弾性回復によって、前記インプラントが治療対象の欠損の形状と一致する、請求項9に記載のインプラント。
- 前記孔のサイズが25〜1000μmである、請求項2に記載のインプラント。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/171,248 US7166133B2 (en) | 2002-06-13 | 2002-06-13 | Devices and methods for treating defects in the tissue of a living being |
PCT/US2003/019622 WO2005004755A1 (en) | 2002-06-13 | 2003-06-14 | Devices for treating defects in the tissue of a living being |
Publications (2)
Publication Number | Publication Date |
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JP2006527009A JP2006527009A (ja) | 2006-11-30 |
JP4635276B2 true JP4635276B2 (ja) | 2011-02-23 |
Family
ID=40296077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2005503939A Expired - Lifetime JP4635276B2 (ja) | 2002-06-13 | 2003-06-14 | 生体組織における欠損を治療するための装置および方法 |
Country Status (6)
Country | Link |
---|---|
US (15) | US7166133B2 (ja) |
EP (2) | EP1648347B1 (ja) |
JP (1) | JP4635276B2 (ja) |
AU (1) | AU2003243711A1 (ja) |
CA (1) | CA2503904C (ja) |
WO (1) | WO2005004755A1 (ja) |
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- 2003-06-14 JP JP2005503939A patent/JP4635276B2/ja not_active Expired - Lifetime
- 2003-06-14 EP EP03817461A patent/EP1648347B1/en not_active Revoked
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