JP5292533B2 - インプラントおよび関節疾患の治療、置換および治療方法 - Google Patents
インプラントおよび関節疾患の治療、置換および治療方法 Download PDFInfo
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- JP5292533B2 JP5292533B2 JP2008528250A JP2008528250A JP5292533B2 JP 5292533 B2 JP5292533 B2 JP 5292533B2 JP 2008528250 A JP2008528250 A JP 2008528250A JP 2008528250 A JP2008528250 A JP 2008528250A JP 5292533 B2 JP5292533 B2 JP 5292533B2
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- A61F2310/00011—Metals or alloys
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- A61F2310/00131—Tantalum or Ta-based alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00395—Coating or prosthesis-covering structure made of metals or of alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00395—Coating or prosthesis-covering structure made of metals or of alloys
- A61F2310/00407—Coating made of titanium or of Ti-based alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00964—Coating or prosthesis-covering structure made of cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
- A61F2310/00982—Coating made of collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
- A61F2310/00988—Coating made of fibrin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Dispersion Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Description
実施例1
実施例2
実施例3
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実施例7
実施例8
実施例9
Claims (19)
- 軟骨細胞;および
少なくとも1つの小柱金属を含む軟骨下基盤
を含み、該軟骨下基盤が少なくとも1つの多孔質表面層および中心部を含み、該少なくとも1つの多孔質表面層が、メディアン径が3μmないし800μmである複数の小孔を含み、ここに、該少なくとも1つの多孔質表面層の該複数の小孔のメディアン径が、該軟骨下基盤の中心部の複数の小孔のそれとは異なる、関節疾患、欠損または損傷の治療を必要としている患者へ施すためのインプラント。 - 該中心部が、メディアン径が100μmないし800μmである複数の小孔を含む、請求項1記載のインプラント。
- 該軟骨細胞が軟骨組織に含まれる、請求項1または2記載のインプラント。
- 該少なくとも1つの多孔質表面層が軟骨細胞−付着表面を含む、請求項1、2または3記載のインプラント。
- 軟骨組織に含まれる軟骨細胞;ならびに
100μmないし800μmのメディアン小孔径を有する複数の小孔を有する小柱金属を含む第一の表面、および軟骨細胞−付着表面を含む第二の表面を含む軟骨下基盤
を含む、関節疾患、欠損または損傷の治療を必要としている患者へ施すためのインプラント。 - 該軟骨細胞または軟骨細胞−付着表面が、3μmないし20μmのメディアン径を有する複数の小孔を含む、請求項4または5記載のインプラント。
- 該軟骨細胞または軟骨細胞−付着表面が接着剤を含む、請求項4、5または6記載のインプラント。
- 該接着剤がフィブリンを含む、請求項7記載のインプラント。
- 該軟骨細胞または軟骨細胞−付着表面が非-小柱金属材料を含む、請求項4、5、6、7または8記載のインプラント。
- 該非−小柱金属材料がポリマーまたはセラミックを含む、請求項9記載のインプラント。
- 該軟骨細胞が、インプラントが施される患者に対して同種異系である軟骨細胞を含む、請求項1〜10のいずれかに記載のインプラント。
- 該軟骨細胞がヒトの死体由来の軟骨細胞を含む、請求項1〜11のいずれかに記載のインプラント。
- 該軟骨細胞が若年性の軟骨細胞を含む、請求項1〜12のいずれかに記載のインプラント。
- 該軟骨細胞が細分化された軟骨組織に含まれる、請求項1〜13のいずれかに記載のインプラント。
- 該軟骨細胞がインビトロで軟骨下基盤に結合された、請求項1〜14のいずれかに記載のインプラント。
- 該軟骨細胞がインビトロで培養された、請求項1〜15のいずれかに記載のインプラント。
- 該軟骨細胞が、軟骨下基盤の少なくとも一部と接触してインビトロで培養された、請求項1〜16のいずれかに記載のインプラント。
- 該小柱金属が、タンタル、ニオブ、ステンレス鋼、クロム-コバルト合金、クロム-コバルト-モリブデン合金、チタンまたはそれらの組合せを含む、請求項1〜17のいずれかに記載のインプラント。
- 該小柱金属がタンタルを含む、請求項1〜18のいずれかに記載のインプラント。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71200405P | 2005-08-26 | 2005-08-26 | |
US60/712,004 | 2005-08-26 | ||
PCT/US2006/033687 WO2007025290A2 (en) | 2005-08-26 | 2006-08-28 | Implants and methods for repair, replacement and treatment of joint disease |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2009505754A JP2009505754A (ja) | 2009-02-12 |
JP2009505754A5 JP2009505754A5 (ja) | 2009-10-15 |
JP5292533B2 true JP5292533B2 (ja) | 2013-09-18 |
Family
ID=37772531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008528250A Expired - Fee Related JP5292533B2 (ja) | 2005-08-26 | 2006-08-28 | インプラントおよび関節疾患の治療、置換および治療方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8480757B2 (ja) |
EP (1) | EP1916964A4 (ja) |
JP (1) | JP5292533B2 (ja) |
AU (1) | AU2006282754A1 (ja) |
WO (1) | WO2007025290A2 (ja) |
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- 2006-08-28 WO PCT/US2006/033687 patent/WO2007025290A2/en active Application Filing
- 2006-08-28 US US12/063,291 patent/US8480757B2/en not_active Expired - Fee Related
- 2006-08-28 JP JP2008528250A patent/JP5292533B2/ja not_active Expired - Fee Related
- 2006-08-28 EP EP06813900.5A patent/EP1916964A4/en not_active Withdrawn
- 2006-08-28 AU AU2006282754A patent/AU2006282754A1/en not_active Abandoned
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WO2007025290A3 (en) | 2007-10-18 |
US8480757B2 (en) | 2013-07-09 |
JP2009505754A (ja) | 2009-02-12 |
EP1916964A4 (en) | 2015-11-04 |
AU2006282754A2 (en) | 2008-03-06 |
WO2007025290A2 (en) | 2007-03-01 |
US20090143867A1 (en) | 2009-06-04 |
AU2006282754A1 (en) | 2007-03-01 |
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