JP2022503879A - がん治療におけるentファミリートランスポーター阻害剤の使用及びそのアデノシン受容体アンタゴニストとの組み合わせ - Google Patents
がん治療におけるentファミリートランスポーター阻害剤の使用及びそのアデノシン受容体アンタゴニストとの組み合わせ Download PDFInfo
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US201862737717P | 2018-09-27 | 2018-09-27 | |
US62/737,717 | 2018-09-27 | ||
BE20180115A BE1026612B1 (fr) | 2018-09-27 | 2018-09-27 | Utilisation d’un inhibiteur d’un transporteur de la famille ent dans le traitement du cancer et combinaison de celui-ci avec un antagoniste de recepteur de l’adenosine |
BE2018/0115 | 2018-09-27 | ||
PCT/EP2019/076244 WO2020065036A1 (fr) | 2018-09-27 | 2019-09-27 | Utilisation d'un inhibiteur d'un transporteur de la famille des ent dans le traitement du cancer et de la combinaison de ceux-ci avec un antagoniste du récepteur de l'adénosine |
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BR (1) | BR112021006033A2 (fr) |
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SI3601296T1 (sl) | 2017-03-30 | 2022-10-28 | iTeos Belgium SA | 2-okso-tiazolni derivati kot zaviralci A2A in spojine za uporabo pri zdravljenju raka |
US11376255B2 (en) | 2018-09-11 | 2022-07-05 | iTeos Belgium SA | Thiocarbamate derivatives as A2A inhibitors, pharmaceutical composition thereof and combinations with anticancer agents |
AU2020395495B2 (en) * | 2019-12-02 | 2024-05-09 | Astrazeneca Ab | Solid pharmaceutical formulations of 6-(2-chloro-6-methylpyridin-4-yl)-5-(-4-fluorophenyl)-1,2,4-triazin-3-amine |
WO2022178135A1 (fr) | 2021-02-17 | 2022-08-25 | Iteos Belguim Sa | Composés, compositions et procédés de traitement de ces derniers |
WO2023056910A1 (fr) * | 2021-10-06 | 2023-04-13 | iTeos Belgium SA | Procédés de préparation d'un composé macrocyclique ayant une activité inhibitrice de l'ent1 |
WO2023059739A1 (fr) * | 2021-10-06 | 2023-04-13 | iTeos Belgium SA | Composés macrocycliques ayant une activité d'inhibition de l'ent1 |
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WO2007140181A2 (fr) * | 2006-05-26 | 2007-12-06 | King Pharmaceuticals Research And Development, Inc. | Polythérapie comprenant un inhibiteur de fixation de l'adénosine et un antagoniste des récepteurs de l'adénosine non sélectif |
WO2009011897A1 (fr) * | 2007-07-17 | 2009-01-22 | Combinatorx, Incorporated | Combinaisons pour le traitement des troubles prolifératifs des lymphocytes b |
GB0906579D0 (en) | 2009-04-16 | 2009-05-20 | Vernalis R&D Ltd | Pharmaceuticals, compositions and methods of making and using the same |
CN102869631B (zh) | 2010-02-08 | 2016-09-07 | 埃西勒国际通用光学公司 | 包含具有防雾性能的抗反射涂层的光学制品 |
ES2365960B1 (es) | 2010-03-31 | 2012-06-04 | Palobiofarma, S.L | Nuevos antagonistas de los receptores de adenosina. |
US20130267515A1 (en) * | 2010-10-26 | 2013-10-10 | Alberta Health Services | Combination comprising an atp analog and an adenosine receptor antagonist or a nucleobase/nucleoside analog for the treatment of cancer |
KR102611446B1 (ko) | 2017-01-20 | 2023-12-06 | 아르커스 바이오사이언시즈 인코포레이티드 | 암-관련 장애의 치료를 위한 아졸로피리미딘 |
WO2018178338A1 (fr) | 2017-03-30 | 2018-10-04 | Iteos Therapeutics | Dérivés de 2-oxo-thiazole en tant qu'inhibiteurs de a2a et composés destinés à être utilisés dans le traitement de cancers |
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