JP2019131713A - 親水性基材 - Google Patents
親水性基材 Download PDFInfo
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- JP2019131713A JP2019131713A JP2018015011A JP2018015011A JP2019131713A JP 2019131713 A JP2019131713 A JP 2019131713A JP 2018015011 A JP2018015011 A JP 2018015011A JP 2018015011 A JP2018015011 A JP 2018015011A JP 2019131713 A JP2019131713 A JP 2019131713A
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F120/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F120/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F120/10—Esters
- C08F120/26—Esters containing oxygen in addition to the carboxy oxygen
- C08F120/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/10—Esters
- C08F20/26—Esters containing oxygen in addition to the carboxy oxygen
- C08F20/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/042—Coating with two or more layers, where at least one layer of a composition contains a polymer binder
- C08J7/0423—Coating with two or more layers, where at least one layer of a composition contains a polymer binder with at least one layer of inorganic material and at least one layer of a composition containing a polymer binder
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/056—Forming hydrophilic coatings
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/315—Compounds containing carbon-to-nitrogen triple bonds
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2500/00—Characteristics or properties of obtained polyolefins; Use thereof
- C08F2500/01—High molecular weight, e.g. >800,000 Da.
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
- C08J2333/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
- C08J2333/14—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
- C08J2333/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
- C08J2333/14—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
- C08J2333/16—Homopolymers or copolymers of esters containing halogen atoms
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- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
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Abstract
Description
なお、本明細書において、表面粗さRaは、JIS B0601−2001で規定される中心線表面粗さRaである。
(1)、(2)の保持、乾燥時間は、基材の大きさ、導入する液種、等により適宜設定すれば良い。保持時間は、5分〜10時間が好ましく、10分〜5時間がより好ましく、15分〜2時間が更に好ましい。乾燥は、室温(約23℃)から80℃で行うことが好ましく、室温から50℃で行うことがより好ましい。また、減圧して乾燥しても良い。更に、保持して一定時間後、適宜、余分な親水性ポリマー溶液・分散液を排出し、乾燥してもよい。
AIBN(アゾビスイソブチロニトリル)12.5mg/mlメタノール溶液を用いて、2−メトキシエチルアクリレート(45wt%メタノール)を60℃で7時間熱重合し、ポリ2−メトキシエチルアクリレートを作製した。
AIBN(アゾビスイソブチロニトリル)を用いて、2−メトキシエチルアクリレート(68wt%メタノール)を60℃で7時間熱重合し、ポリ2−メトキシエチルアクリレートを作製した。
AIBN(アゾビスイソブチロニトリル)を用いて、2−メトキシエチルアクリレート(23wt%メタノール)を60℃で7時間熱重合し、ポリ2−メトキシエチルアクリレートを作製した。
上記で得られたポリ2−メトキシエチルアクリレートのMw、Mnを前述の方法で測定した。
親水性基材の親水性ポリマー層の膜厚は、親水性ポリマー層の断面を、TEMを使用し、加速電圧15kV、1000倍で測定(撮影)した。
親水性基材の親水性ポリマー層の表面に蒸留水2μlを滴下し、30秒後の接触角をθ/2法(室温)で測定した。
レーザー顕微鏡を用いて、非接触で表面粗さを1つの親水性基材(親水性ポリマー層)で4箇所(第1ピーク)測定し、そのRaの4点の平均を表面粗さRaとした(JIS B0601−2001で規定される中心線表面粗さRaの平均)。
Claims (4)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018015011A JP7358030B2 (ja) | 2018-01-31 | 2018-01-31 | 親水性基材 |
CN201811427625.0A CN110093081B (zh) | 2018-01-31 | 2018-11-27 | 亲水性基材 |
EP18210687.2A EP3521351B1 (en) | 2018-01-31 | 2018-12-06 | Hydrophilic substrate |
US16/237,923 US10975176B2 (en) | 2018-01-31 | 2019-01-02 | Hydrophilic substrate |
Applications Claiming Priority (1)
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---|---|---|---|
JP2018015011A JP7358030B2 (ja) | 2018-01-31 | 2018-01-31 | 親水性基材 |
Publications (2)
Publication Number | Publication Date |
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JP2019131713A true JP2019131713A (ja) | 2019-08-08 |
JP7358030B2 JP7358030B2 (ja) | 2023-10-10 |
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JP2018015011A Active JP7358030B2 (ja) | 2018-01-31 | 2018-01-31 | 親水性基材 |
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US (1) | US10975176B2 (ja) |
EP (1) | EP3521351B1 (ja) |
JP (1) | JP7358030B2 (ja) |
CN (1) | CN110093081B (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6779483B2 (ja) | 2016-09-29 | 2020-11-04 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
JP7109719B2 (ja) | 2018-02-14 | 2022-08-01 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
JP7158671B2 (ja) * | 2018-02-14 | 2022-10-24 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
US11614440B2 (en) | 2019-01-24 | 2023-03-28 | Sumitomo Rubber Industries, Ltd. | Specific cell fractionating and capturing methods |
JP2021187907A (ja) * | 2020-05-27 | 2021-12-13 | 住友ゴム工業株式会社 | 親水性基材及び親水性基材作製方法 |
EP4389714A1 (en) * | 2022-12-23 | 2024-06-26 | Sumitomo Rubber Industries, Ltd. | Polymer-coated glass substrate |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004244605A (ja) * | 2002-12-16 | 2004-09-02 | Takemoto Oil & Fat Co Ltd | 合成高分子フィルム用表面処理剤、合成高分子フィルムの表面処理方法及び表面処理合成高分子フィルム |
JP2007031545A (ja) * | 2005-07-26 | 2007-02-08 | Takemoto Oil & Fat Co Ltd | 防曇性樹脂シート及び防曇性成形体 |
JP2008534062A (ja) * | 2005-03-24 | 2008-08-28 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 非汚染性メタクリレート又はアクリレートポリマーから形成された埋め込み型デバイス |
WO2014171448A1 (ja) * | 2013-04-18 | 2014-10-23 | 国立大学法人 山形大学 | 胆管留置用ステント及びその製造方法 |
JP2017025285A (ja) * | 2015-03-10 | 2017-02-02 | テルモ株式会社 | 抗血栓性コーティング材の製造方法 |
JP2017082174A (ja) * | 2015-10-30 | 2017-05-18 | 国立大学法人山形大学 | ポリマー、ポリマー溶液及びポリマー被覆基板 |
JP2017080263A (ja) * | 2015-10-30 | 2017-05-18 | 株式会社パイオラックスメディカルデバイス | 消化器系ステント |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04135565A (ja) * | 1990-09-28 | 1992-05-11 | Terumo Corp | 人工皮膚 |
US6468649B1 (en) * | 1995-02-22 | 2002-10-22 | Scimed Life Systems, Inc. | Antimicrobial adhesion surface |
US7008979B2 (en) | 2002-04-30 | 2006-03-07 | Hydromer, Inc. | Coating composition for multiple hydrophilic applications |
US20080008736A1 (en) * | 2006-07-06 | 2008-01-10 | Thierry Glauser | Random copolymers of methacrylates and acrylates |
JP5467715B2 (ja) * | 2007-09-03 | 2014-04-09 | 株式会社Uacj | アルミニウム用親水性潤滑塗料、及びそれを用いた被塗物 |
KR101234133B1 (ko) * | 2008-05-26 | 2013-02-19 | 하리마 카세이 가부시키가이샤 | 친수성 피복제, 친수성 피막 및 친수성 기재 |
JP5777621B2 (ja) * | 2010-07-29 | 2015-09-09 | 三井化学株式会社 | 単層膜およびこれからなる親水性材料 |
US9493600B2 (en) * | 2011-08-10 | 2016-11-15 | Jsr Corporation | Polymer, surface hydrophilizing agent containing said polymer, and manufacturing method for substrate having hydrophilic surface |
KR102087646B1 (ko) * | 2015-03-27 | 2020-03-11 | 후지필름 가부시키가이샤 | 패턴 형성 방법, 레지스트 패턴, 전자 디바이스의 제조 방법, 및 상층막 형성용 조성물 |
EP3244208A1 (en) * | 2016-05-09 | 2017-11-15 | Sumitomo Rubber Industries, Ltd. | Medical analysis device and cell analysis method |
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2018
- 2018-01-31 JP JP2018015011A patent/JP7358030B2/ja active Active
- 2018-11-27 CN CN201811427625.0A patent/CN110093081B/zh active Active
- 2018-12-06 EP EP18210687.2A patent/EP3521351B1/en active Active
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2019
- 2019-01-02 US US16/237,923 patent/US10975176B2/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004244605A (ja) * | 2002-12-16 | 2004-09-02 | Takemoto Oil & Fat Co Ltd | 合成高分子フィルム用表面処理剤、合成高分子フィルムの表面処理方法及び表面処理合成高分子フィルム |
JP2008534062A (ja) * | 2005-03-24 | 2008-08-28 | アボット カーディオヴァスキュラー システムズ インコーポレイテッド | 非汚染性メタクリレート又はアクリレートポリマーから形成された埋め込み型デバイス |
JP2007031545A (ja) * | 2005-07-26 | 2007-02-08 | Takemoto Oil & Fat Co Ltd | 防曇性樹脂シート及び防曇性成形体 |
WO2014171448A1 (ja) * | 2013-04-18 | 2014-10-23 | 国立大学法人 山形大学 | 胆管留置用ステント及びその製造方法 |
JP2017025285A (ja) * | 2015-03-10 | 2017-02-02 | テルモ株式会社 | 抗血栓性コーティング材の製造方法 |
JP2017082174A (ja) * | 2015-10-30 | 2017-05-18 | 国立大学法人山形大学 | ポリマー、ポリマー溶液及びポリマー被覆基板 |
JP2017080263A (ja) * | 2015-10-30 | 2017-05-18 | 株式会社パイオラックスメディカルデバイス | 消化器系ステント |
Also Published As
Publication number | Publication date |
---|---|
JP7358030B2 (ja) | 2023-10-10 |
EP3521351A1 (en) | 2019-08-07 |
US20190233555A1 (en) | 2019-08-01 |
EP3521351B1 (en) | 2020-06-17 |
CN110093081A (zh) | 2019-08-06 |
CN110093081B (zh) | 2022-05-17 |
US10975176B2 (en) | 2021-04-13 |
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