JP2018526160A - 磁性マーカ局在化(mml)のためのマーカ材料 - Google Patents
磁性マーカ局在化(mml)のためのマーカ材料 Download PDFInfo
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- JP2018526160A JP2018526160A JP2018515358A JP2018515358A JP2018526160A JP 2018526160 A JP2018526160 A JP 2018526160A JP 2018515358 A JP2018515358 A JP 2018515358A JP 2018515358 A JP2018515358 A JP 2018515358A JP 2018526160 A JP2018526160 A JP 2018526160A
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Abstract
Description
本出願は、2015年6月4日に出願された米国仮特許出願番号第62/170,768号からの優先権を主張しており、その内容は、その全体が参考として本明細書中に援用される。
本発明は、概して、医療検出のためのマーカの分野に関し、より具体的には、磁気医療マーカに関する。
マンモグラフィスクリーニングプログラムの普及の増加に伴って、***温存治療を受けることができる、小触知不能(または、潜在的)病変のような乳癌の大部分が、検出される。触知不能乳癌の正確な局在化は、適正なエッジを伴って、完全腫瘍の外科手術的除去を可能にするために重要である。腫瘍が完全に切除されない場合、患者は、さらなる手術を受け、任意の残っている癌性組織を除去する必要がある。正確な局在化はまた、有害な審美的結果をもたらし得る、過剰な***組織の切除を回避することに役立つ。正確な局在化は、結腸直腸、前立腺、および肺等の他の癌ならびに当業者によって公知の他の状態によっても要求される。
本発明は、外科手術用途のための磁気マーカに関する。特に、いったん展開されると、展開に先立ってその幾何学形状から予期されるであろうものより均一な磁気応答を伴う、磁気マーカに関する。
磁気マーカを永久磁石として作製するための方法は、米国特許第6,173,715号に説明されている。永久磁石インプラントは、近傍における任意の磁性材料を誘引し、したがって、例えば、磁性材料から作製される外科手術用ツールが近傍にあるとき、望ましくなく、他のインプラントと相互作用するか、または組織内で移動し得るという短所を有する。
磁化率の異方性=最大磁化率/最小磁化率
Claims (19)
- 身体内の組織中の部位をマークするための送達デバイス内に保持される、パックされる磁気マーカであって、展開に先立って非球状構成を備え、5未満の展開後の最大磁気応答と最小磁気応答の比(磁化率の磁気異方性比)を有する、磁気マーカ。
- 展開前の前記マーカのアスペクト比(長さ対直径)は、4を上回る、請求項1に記載の磁気マーカ。
- 展開前の前記マーカの磁化率の磁気異方性比は、5を上回る、請求項1に記載の磁気マーカ。
- 前記マーカは、磁化率のより高い磁気異方性を有するパック構成と、磁化率のより低い磁気異方性を有する展開/非パック構成との間で弾力により変形可能である、請求項1に記載の磁気マーカ。
- 前記マーカは、より高い投影面積異方性比を有するパック構成と、より低い投影面積異方性比を有する展開/非パック構成との間で弾力により変形可能である、請求項1に記載の磁気マーカ。
- 前記非球状構成は、円筒形、ケーブル、ビーズ、「ダンベル状」形態、およびヤーンのボールから成る群から選択される形状である、請求項1に記載の磁気マーカ。
- 前記円筒形またはケーブルは、組織内への留置の際に屈曲する、請求項6に記載の磁気マーカ。
- 前記非球状構成は、6未満の異方性比を有する、請求項1に記載の磁気マーカ。
- 前記非球状構成は、3未満の磁化率の磁気異方性比を有する、請求項1に記載の磁気マーカ。
- 前記非球状構成は、小面を有する、請求項1に記載の磁気マーカ。
- 1つまたはそれを上回る磁性材料を含み、前記磁性材料は、好ましくは、>0.05、より好ましくは、>1さらにより好ましくは、>5m3kg-1の磁気質量磁化率を有する、請求項1に記載の磁気マーカ。
- 1つまたはそれを上回る磁性材料から成り、前記磁性材料は、100Oe未満の保磁力を有する、請求項1に記載の磁気マーカ。
- 身体内の組織中の部位をマークするための磁気マーカであって、前記部位内への留置の際に再構成する、可撓性非磁気構成要素によって連結される複数の磁気構成要素を備える、磁気マーカ。
- 身体内の組織中の部位をマークするための磁気マーカであって、第2の形状の非磁気マトリクス内に位置する第1の形状の1つまたはそれを上回る材料から作製される、磁気構成要素を備える、磁気マーカ。
- 身体内の組織中の部位をマークするための磁気マーカであって、磁性材料シース内の磁性材料コアを備える、磁気マーカ。
- 前記コアおよび前記シースのうちの1つは、100Oe未満の保磁力を伴う、軟質磁性材料から成る、請求項15に記載の磁気マーカ。
- 身体内の組織中の部位をマークするための磁気マーカであって、前記身体の中への前記マーカの留置に続いて、前記磁気マーカに自己組織化する、複数の磁気構成要素を備える、磁気マーカ。
- 前記磁気構成要素はそれぞれ、疎水性コーティング内に封入される、請求項17に記載の磁気マーカ。
- 磁性金属ガラスを含む、身体内の組織中の部位をマークするための磁気マーカ。
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021005955A1 (ja) * | 2019-07-10 | 2021-01-14 | 京都府公立大学法人 | 医療用イメージガイダンスマーカー |
WO2023007702A1 (ja) * | 2021-07-30 | 2023-02-02 | 株式会社マトリックス細胞研究所 | 磁性マーカセット、磁性マーカ配置方法 |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9936892B1 (en) | 2009-05-04 | 2018-04-10 | Cortex Manufacturing Inc. | Systems and methods for providing a fiducial marker |
WO2014081940A1 (en) | 2012-11-21 | 2014-05-30 | Trustees Of Boston University | Tissue markers and uses thereof |
JP2018516129A (ja) * | 2015-06-04 | 2018-06-21 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 近接照射療法シードといったオブジェクト位置の決定 |
CN105852984B (zh) * | 2016-03-23 | 2020-02-18 | 堃博生物科技(上海)有限公司 | 肺内标记物 |
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GB2582123B (en) * | 2018-01-25 | 2021-04-28 | Endomagnetics Ltd | Systems and methods for detecting magnetic markers for surgical guidance |
GB2573500B (en) | 2018-03-23 | 2020-11-04 | Endomagnetics Ltd | Magnetic markers for surgical guidance |
EP3864507A4 (en) * | 2018-10-12 | 2022-07-20 | Hologic, Inc. | TISSUE LOCATING DEVICE AND METHOD OF USE |
US11266481B2 (en) | 2018-10-12 | 2022-03-08 | Hologic, Inc. | Tissue localization marker with D-shaped cross-section |
WO2020154934A1 (zh) * | 2019-01-30 | 2020-08-06 | 唐山哈船科技有限公司 | 手术辅助*** |
KR102251651B1 (ko) * | 2019-03-19 | 2021-05-14 | 오스템임플란트 주식회사 | 파노라믹 영상 생성을 위한 커브 라인 자동 생성방법 및 이를 위한 치과영상 처리장치 |
EP4278985A3 (en) * | 2019-05-30 | 2024-02-21 | Devicor Medical Products, Inc. | Biopsy site marker for limited migration |
GB2585034A (en) * | 2019-06-25 | 2020-12-30 | Endomagnetics Ltd | Hyperthermia implants and a method and system for heating the implant |
WO2021081079A1 (en) * | 2019-10-23 | 2021-04-29 | Clemson University | A breast tissue marker and localization system |
US11166782B1 (en) | 2020-07-19 | 2021-11-09 | Sirius Medical Systems B.V. | Implantable marker and a method of implanting markers |
US20230285109A1 (en) * | 2020-10-07 | 2023-09-14 | Camtomsam AB | Radiation therapy reference positioning marker |
GB2612598B (en) * | 2021-11-03 | 2024-03-20 | Endomagnetics Ltd | Magnetic markers for imaging and surgical guidance |
GB2612597B (en) * | 2021-11-03 | 2024-06-12 | Endomagnetics Ltd | Improvements in or relating to implantable ferromagnetic markers |
GB2620722A (en) | 2022-04-05 | 2024-01-24 | Endomagnetics Ltd | Improvements in or relating to susceptibility probes for detecting surgical markers |
GB2617357A (en) | 2022-04-05 | 2023-10-11 | Endomagnetics Ltd | Improvements in or relating to susceptibility probes for detecting surgical markers |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002004118A (ja) * | 2000-06-21 | 2002-01-09 | Unitika Ltd | 徘徊患者用衣服 |
US20080097199A1 (en) * | 2004-08-20 | 2008-04-24 | David Mullen | Tissue Marking Devices and Systems |
JP2008143896A (ja) * | 2006-11-21 | 2008-06-26 | Suros Surgical Systems Inc | 複数の物理療法で視認可能な部位マーカー |
JP2012177691A (ja) * | 2011-02-04 | 2012-09-13 | Hitachi Maxell Ltd | 磁性マーカー粒子 |
JP2013085642A (ja) * | 2011-10-17 | 2013-05-13 | Tokyo Denki Univ | 医療用チューブの先端位置検出システムおよび当該システムに適用する医療用チューブ |
US20140018663A1 (en) * | 2012-07-16 | 2014-01-16 | Endomagnetics Ltd. | Magnetic Marker for Surgical Localization |
Family Cites Families (169)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2614164A (en) | 1947-11-12 | 1952-10-14 | Schlumberger Well Surv Corp | Mutual inductance system |
US3449662A (en) | 1963-10-16 | 1969-06-10 | American Mach & Foundry | Magnetic inspection method and apparatus using resilient magnetizing means and resilient sensors |
US3445928A (en) | 1966-03-25 | 1969-05-27 | Bunker Ramo | Magnetometer method of manufacture |
US3492566A (en) | 1967-09-01 | 1970-01-27 | Canadian Patents Dev | Three dimensional magnetic anisotropic susceptibility meter |
US4324255A (en) | 1980-03-07 | 1982-04-13 | Barach John P | Method and apparatus for measuring magnetic fields and electrical currents in biological and other systems |
GB2109112A (en) | 1981-10-06 | 1983-05-25 | Pantatron Systems Limited | Eddy current test probe |
JPH0768117B2 (ja) | 1983-05-06 | 1995-07-26 | ベスター・インコーポレイテツド | 薬剤放出調整用小胞製剤 |
US4823113A (en) * | 1986-02-27 | 1989-04-18 | Allied-Signal Inc. | Glassy alloy identification marker |
US5055288A (en) | 1987-06-26 | 1991-10-08 | Advanced Magnetics, Inc. | Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides |
US5261403A (en) | 1987-03-30 | 1993-11-16 | Hitachi, Ltd. | Magnetic resonance imaging apparatus |
US5414356A (en) | 1987-09-21 | 1995-05-09 | Hitachi, Ltd. | Fluxmeter including squid and pickup coil with flux guiding core and method for sensing degree of deterioration of an object |
US4825162A (en) | 1987-12-07 | 1989-04-25 | General Electric Company | Nuclear magnetic resonance (NMR) imaging with multiple surface coils |
JP2613275B2 (ja) | 1988-09-16 | 1997-05-21 | 株式会社日立製作所 | 超電導量子干渉素子を用いた磁束計 |
EP0390935A1 (de) | 1989-03-29 | 1990-10-10 | Siemens Aktiengesellschaft | Verfahren zum Kalibrieren von Mehrkanal-Squid-Systemen mit Gradiometern beliebiger Ordnung |
US5442289A (en) | 1989-07-31 | 1995-08-15 | Biomagnetic Technologies, Inc. | Biomagnetometer having flexible sensor |
DE4003330A1 (de) | 1990-02-05 | 1991-08-08 | Foerster Inst Dr Friedrich | Wirbelstrompruefgeraet |
US5005001A (en) | 1990-04-05 | 1991-04-02 | Pitney Bowes Inc. | Field generation and reception system for electronic article surveillance |
US5512821A (en) | 1991-06-04 | 1996-04-30 | Nkk Corporation | Method and apparatus for magnetically detecting defects in an object with compensation for magnetic field shift by means of a compensating coil |
US5293119A (en) | 1992-02-20 | 1994-03-08 | Sqm Technology, Inc. | Electromagnetic microscope for evaluation of electrically conductive and magnetic materials |
JP2882167B2 (ja) | 1992-03-06 | 1999-04-12 | ダイキン工業株式会社 | Squid磁束計 |
FR2689638B1 (fr) | 1992-04-06 | 1996-08-09 | Aerospatiale | Capteur a courants de foucault. |
US5313192A (en) * | 1992-07-02 | 1994-05-17 | Sensormatic Electronics Corp. | Deactivatable/reactivatable magnetic marker having a step change in magnetic flux |
DE69324591T3 (de) | 1992-08-05 | 2004-02-12 | Meito Sangyo K.K., Nagoya | Verbundmaterial mit kleinem durchmesser, welches ein wasserlösliches carboxylpolysaccharid und magnetisches eisenoxid enthaltet |
DE4226814A1 (de) | 1992-08-13 | 1994-02-17 | Philips Patentverwaltung | Spulenanordnung für MR-Untersuchungen der Mamma |
US6023165A (en) | 1992-09-28 | 2000-02-08 | Fonar Corporation | Nuclear magnetic resonance apparatus and methods of use and facilities for incorporating the same |
US5575794A (en) | 1993-02-12 | 1996-11-19 | Walus; Richard L. | Tool for implanting a fiducial marker |
US5537037A (en) | 1993-03-16 | 1996-07-16 | Hitachi, Ltd. | Apparatus with cancel coil assembly for cancelling a field parallel to an axial direction to the plural coils and to a squid pick up coil |
JPH06324021A (ja) | 1993-03-16 | 1994-11-25 | Hitachi Ltd | 非破壊検査装置 |
WO1994024933A1 (en) | 1993-04-26 | 1994-11-10 | St. Louis University | Indicating the position of a surgical probe |
US5590654A (en) | 1993-06-07 | 1997-01-07 | Prince; Martin R. | Method and apparatus for magnetic resonance imaging of arteries using a magnetic resonance contrast agent |
US5363845A (en) | 1993-08-13 | 1994-11-15 | Medical Advances, Inc. | Breast coil for magnetic resonance imaging |
BE1007459A3 (nl) | 1993-08-24 | 1995-07-04 | Philips Electronics Nv | Magnetisch resonantie apparaat. |
US5437280A (en) | 1993-09-20 | 1995-08-01 | Hussman; Karl L. | Magnetic resonance breast localizer |
JPH0815229A (ja) | 1994-06-27 | 1996-01-19 | Mitsubishi Heavy Ind Ltd | 高分解能渦電流探傷装置 |
US5402094A (en) | 1994-08-15 | 1995-03-28 | Enge; Harald A. | MRI mammography magnet |
DE69534233T2 (de) | 1994-09-16 | 2005-10-27 | Ethicon Endo-Surgery, Inc., Cincinnati | Vorrichtungen zum bestimmen und markieren von gewebe |
JP3910222B2 (ja) | 1995-03-10 | 2007-04-25 | 株式会社豊田中央研究所 | 疲労度測定装置 |
US5657756A (en) | 1995-06-07 | 1997-08-19 | Ctf Systems Inc. | Method and systems for obtaining higher order gradiometer measurements with lower order gradiometers |
JP3580905B2 (ja) | 1995-06-13 | 2004-10-27 | 大日本印刷株式会社 | 磁気センサ |
JP3499054B2 (ja) | 1995-07-11 | 2004-02-23 | 独立行政法人 国立印刷局 | 安全保護紙の真偽判定装置 |
US5842986A (en) | 1995-08-16 | 1998-12-01 | Proton Sciences Corp. | Ferromagnetic foreign body screening method and apparatus |
DE19532676C1 (de) | 1995-09-05 | 1997-05-07 | Inst Physikalische Hochtech Ev | Anordnung zur Bestimmung der Position eines Markers in einem Hohlraum innerhalb des Organismus eines Lebewesens |
CZ234898A3 (cs) | 1996-01-25 | 1998-11-11 | Schering Aktiengesellschaft | Zdokonalené koncentrované injekční a infusní roztoky pro intravazální použití |
CA2248076A1 (en) | 1996-03-11 | 1997-09-18 | Richard D. Leavitt | Polymeric delivery of radionuclides and radiopharmaceuticals |
JPH1038854A (ja) | 1996-07-17 | 1998-02-13 | Agency Of Ind Science & Technol | 導電性材料の非破壊検査方法および装置 |
EP1284123B1 (en) | 1996-08-12 | 2005-07-20 | Ethicon Endo-Surgery, Inc. | Apparatus for marking tissue |
AU4070697A (en) | 1996-08-16 | 1998-03-06 | Jon Neal Weaver | Anti-shoplifting security system |
US5844140A (en) | 1996-08-27 | 1998-12-01 | Seale; Joseph B. | Ultrasound beam alignment servo |
US5997473A (en) | 1996-09-06 | 1999-12-07 | Olympus Optical Co., Ltd. | Method of locating a coil which consists of determining the space occupied by a source coil generating a magnetic field |
DE29724862U1 (de) | 1996-09-18 | 2004-12-30 | Ifm Electronic Gmbh | Induktiver Näherungsschalter |
JP2001527641A (ja) | 1996-12-27 | 2001-12-25 | ベーイーツェー−ナイセ ゲゼルシャフト ミット ベシュレンクテル ハフツング ビジネス アンド イノヴェイション センター イン デア オイロレギオーン ナイセ | 磁気共振センサ |
US6406420B1 (en) | 1997-01-02 | 2002-06-18 | Myocor, Inc. | Methods and devices for improving cardiac function in hearts |
WO2000045697A1 (en) | 1997-02-27 | 2000-08-10 | Uri Rapoport | Method and apparatus for detecting a magnetically responsive substance |
GB9712524D0 (en) | 1997-06-16 | 1997-08-20 | Nycomed Imaging As | Method |
FR2770779B1 (fr) | 1997-11-10 | 2000-07-21 | Bernstein Veronique | Solute hypotonique ou hypoosmolaire au plasma utilise dans le traitement de la cellulite, les fibroses, et de l'hirsutisme |
US6270464B1 (en) | 1998-06-22 | 2001-08-07 | Artemis Medical, Inc. | Biopsy localization method and device |
US6205352B1 (en) | 1997-11-19 | 2001-03-20 | Oncology Innovations, Inc. | Sentinel node identification using non-isotope means |
CA2260703A1 (en) * | 1998-04-07 | 1999-10-07 | Dennis W. Szymaitis | Disposal container for detecting, distinguishing and counting objects |
US6161034A (en) | 1999-02-02 | 2000-12-12 | Senorx, Inc. | Methods and chemical preparations for time-limited marking of biopsy sites |
US6347241B2 (en) | 1999-02-02 | 2002-02-12 | Senorx, Inc. | Ultrasonic and x-ray detectable biopsy site marker and apparatus for applying it |
AU2001217746A1 (en) | 1998-05-14 | 2002-05-27 | Calypso Medical, Inc. | Systems and methods for locating and defining a target location within a human body |
US5941890A (en) | 1998-06-26 | 1999-08-24 | Ethicon Endo-Surgery, Inc. | Implantable surgical marker |
KR100372050B1 (ko) * | 1998-11-26 | 2003-02-14 | 스미토모 도큐슈 긴조쿠 가부시키가이샤 | 페라이드 자석분말 및 자석분말을 이용한 자석 및 그제조방법 |
US6356782B1 (en) | 1998-12-24 | 2002-03-12 | Vivant Medical, Inc. | Subcutaneous cavity marking device and method |
US6371904B1 (en) | 1998-12-24 | 2002-04-16 | Vivant Medical, Inc. | Subcutaneous cavity marking device and method |
US6230038B1 (en) | 1999-02-01 | 2001-05-08 | International Business Machines Corporation | Imaging of internal structures of living bodies by sensing implanted magnetic devices |
US6862470B2 (en) | 1999-02-02 | 2005-03-01 | Senorx, Inc. | Cavity-filling biopsy site markers |
US6725083B1 (en) | 1999-02-02 | 2004-04-20 | Senorx, Inc. | Tissue site markers for in VIVO imaging |
US7983734B2 (en) | 2003-05-23 | 2011-07-19 | Senorx, Inc. | Fibrous marker and intracorporeal delivery thereof |
US6173715B1 (en) | 1999-03-01 | 2001-01-16 | Lucent Medical Systems, Inc. | Magnetic anatomical marker and method of use |
GB9908179D0 (en) * | 1999-04-09 | 1999-06-02 | Univ Cambridge Tech | Magnetic materials |
WO2000062672A1 (en) | 1999-04-15 | 2000-10-26 | Surgi-Vision | Methods for in vivo magnetic resonance imaging |
US6963769B1 (en) | 1999-04-21 | 2005-11-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for enhancing contrast produced by MRI |
US6292678B1 (en) * | 1999-05-13 | 2001-09-18 | Stereotaxis, Inc. | Method of magnetically navigating medical devices with magnetic fields and gradients, and medical devices adapted therefor |
US6766186B1 (en) | 1999-06-16 | 2004-07-20 | C. R. Bard, Inc. | Post biospy tissue marker and method of use |
JP2001000430A (ja) | 1999-06-24 | 2001-01-09 | Alcare Co Ltd | 画像撮影用のマ−カ− |
WO2001008578A1 (en) * | 1999-07-30 | 2001-02-08 | Vivant Medical, Inc. | Device and method for safe location and marking of a cavity and sentinel lymph nodes |
US6835572B1 (en) | 1999-10-18 | 2004-12-28 | Institute For Magnetic Resonance Research | Magnetic resonance spectroscopy of breast biopsy to determine pathology, vascularization and nodal involvement |
JP2001255358A (ja) | 2000-03-10 | 2001-09-21 | Sumitomo Electric Ind Ltd | 磁気センサ |
AU2001251348A1 (en) | 2000-04-07 | 2001-10-23 | The Johns-Hopkins University | Apparatus for sensing human prostate tumor |
US6889073B2 (en) | 2000-05-08 | 2005-05-03 | David A. Lampman | Breast biopsy and therapy system for magnetic resonance imagers |
WO2002013713A1 (en) | 2000-08-10 | 2002-02-21 | Cook Incorporated | Localizer needle |
US6394965B1 (en) | 2000-08-15 | 2002-05-28 | Carbon Medical Technologies, Inc. | Tissue marking using biocompatible microparticles |
JP2006500115A (ja) | 2000-11-16 | 2006-01-05 | マイクロスフエリツクス・エル・エル・シー | 密封小線源治療用の可撓性および/または弾性シードまたはストランド |
CA2775170C (en) | 2000-11-20 | 2017-09-05 | Senorx, Inc. | An intracorporeal marker delivery system for marking a tissue site |
FR2823092B1 (fr) | 2001-04-10 | 2004-03-05 | Eurorad 2 6 | Dispositif per-operatoire pour la localisation de tissus marques et procede utilisant un tel dispositif |
AU2002307762A1 (en) * | 2001-04-18 | 2002-10-28 | Bbms Ltd. | Navigating and maneuvering of an in vivo vechicle by extracorporeal devices |
JP4193382B2 (ja) | 2001-07-19 | 2008-12-10 | 株式会社日立製作所 | 磁場計測装置 |
US6850065B1 (en) | 2001-07-27 | 2005-02-01 | General Electric Company | MRI coil system for breast imaging |
US6592608B2 (en) | 2001-12-07 | 2003-07-15 | Biopsy Sciences, Llc | Bioabsorbable sealant |
ITSV20010029A1 (it) | 2001-08-14 | 2003-02-14 | Esaote Spa | Macchina per il rilevamento di immagini in risonanza magnetica nucleare (mri) |
US20030141868A1 (en) | 2001-08-23 | 2003-07-31 | Bakharev Alexander A. | High balance gradiometer |
US7135978B2 (en) | 2001-09-14 | 2006-11-14 | Calypso Medical Technologies, Inc. | Miniature resonating marker assembly |
US7701209B1 (en) | 2001-10-05 | 2010-04-20 | Fonar Corporation | Coils for horizontal field magnetic resonance imaging |
JP4090722B2 (ja) | 2001-10-23 | 2008-05-28 | 純一 小川 | 磁性流体検出装置 |
US20030216632A1 (en) | 2001-10-29 | 2003-11-20 | Mednovus, Inc. | Ferromagnetic sensing method and apparatus |
JP2003149212A (ja) | 2001-11-09 | 2003-05-21 | Japan Science & Technology Corp | 非破壊検査装置 |
US7787931B2 (en) * | 2001-12-03 | 2010-08-31 | Fabian Carl E | Portable surgical implement detector |
WO2003051217A2 (en) | 2001-12-14 | 2003-06-26 | Monteris Medical Inc. | Hyperthermia treatment and probe therefor |
JP2003315373A (ja) | 2002-04-18 | 2003-11-06 | Toshiba Corp | 電流検出装置及び半導体装置 |
US7329414B2 (en) | 2002-05-03 | 2008-02-12 | Biopsy Sciences, Llc | Biodegradable polymer for marking tissue and sealing tracts |
JP4221192B2 (ja) | 2002-06-14 | 2009-02-12 | 株式会社日立ハイテクノロジーズ | 生体磁気計測装置 |
US20040162477A1 (en) | 2002-10-04 | 2004-08-19 | Olympus Corporation | Apparatus for detecting magnetic fluid identifying sentinel-lymph node |
US20060173283A1 (en) | 2002-11-27 | 2006-08-03 | Oskar Axelsson | Method of magnetic resonance imaging |
US7412275B2 (en) | 2002-12-13 | 2008-08-12 | Mauro Marinelli | Susceptometer for non-invasive iron level measurement in a body |
US7009398B2 (en) | 2003-03-20 | 2006-03-07 | Siemens Aktiengesellschaft | Portable magnetic resonance surface coil unit with an access opening for manual gripping |
US7877133B2 (en) | 2003-05-23 | 2011-01-25 | Senorx, Inc. | Marker or filler forming fluid |
US7783336B2 (en) | 2003-06-06 | 2010-08-24 | Ethicon Endo-Surgery, Inc. | Subcutaneous biopsy cavity marker device |
US7744852B2 (en) * | 2003-07-25 | 2010-06-29 | Rubicor Medical, Llc | Methods and systems for marking post biopsy cavity sites |
US20050033157A1 (en) | 2003-07-25 | 2005-02-10 | Klein Dean A. | Multi-modality marking material and method |
US7001341B2 (en) | 2003-08-13 | 2006-02-21 | Scimed Life Systems, Inc. | Marking biopsy sites |
US7084631B2 (en) | 2003-11-19 | 2006-08-01 | General Electric Company | Magnetic resonance imaging array coil system and method for breast imaging |
EP1541083A3 (en) | 2003-12-09 | 2006-03-01 | Olympus Corporation | Magnetic fluid detection device |
JP4217599B2 (ja) | 2003-12-09 | 2009-02-04 | オリンパス株式会社 | 磁性流体検出装置 |
US8118754B1 (en) | 2007-11-15 | 2012-02-21 | Flynn Edward R | Magnetic needle biopsy |
US7386338B2 (en) | 2004-04-30 | 2008-06-10 | General Electric Company | Bilateral imaging apparatus |
US7708751B2 (en) | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
JP3896489B2 (ja) | 2004-07-16 | 2007-03-22 | 国立大学法人 岡山大学 | 磁気検知装置及び物質判定装置 |
US7116094B2 (en) | 2004-07-28 | 2006-10-03 | International Business Machines Corporation | Apparatus and method for transmission and remote sensing of signals from integrated circuit devices |
US20060074295A1 (en) | 2004-10-01 | 2006-04-06 | Nexgen | Combined MR coil technology in medical devices |
US20060079805A1 (en) * | 2004-10-13 | 2006-04-13 | Miller Michael E | Site marker visable under multiple modalities |
US8280486B2 (en) | 2004-10-13 | 2012-10-02 | Suros Surgical Systems, Inc. | Site marker visable under multiple modalities |
US20100125191A1 (en) | 2004-11-18 | 2010-05-20 | Nedim Turan Sahin | Mri as a therapeutic device |
WO2006056739A2 (en) | 2004-11-23 | 2006-06-01 | Quantum Medical Technology Limited | Surgical tag, magnetometer, and associated system |
JP5226319B2 (ja) | 2004-12-22 | 2013-07-03 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 磁気粒子の空間分布を定めるための配置および方法 |
US20090299176A1 (en) * | 2004-12-22 | 2009-12-03 | Koninklijke Philips Electronics, N.V. | Marker for position determination with a magnetic method |
DE102005002944A1 (de) * | 2005-01-18 | 2006-07-27 | Charité - Universitätsmedizin Berlin (Charité) | Endoskopisches Markierungsmittel sowie Instrumente zur Applikation und Detektion des Markierungsmittels sowie zur operativen Fixierung des markierten Gewebebereichs |
US8467849B2 (en) | 2005-02-03 | 2013-06-18 | ORGAMEND Inc. | Magnetic resonance imaging device |
US7842178B2 (en) * | 2005-04-18 | 2010-11-30 | University Of Iowa Research Foundation | Magnet incorporated electrically conductive electrodes |
GB2425610A (en) | 2005-04-29 | 2006-11-01 | Univ London | Magnetic properties sensing system |
US7831293B2 (en) | 2005-05-10 | 2010-11-09 | Advanced Clinical Solutions, Inc. | Method of defining a biological target for treatment |
US20060293581A1 (en) | 2005-05-12 | 2006-12-28 | Sunnybrook And Women's College Health Sciences Centre | Marker device for X-ray, ultrasound and MR imaging |
US7570056B2 (en) | 2005-08-10 | 2009-08-04 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging apparatus |
GB0519391D0 (en) | 2005-09-22 | 2005-11-02 | Aion Diagnostics Ltd | Imaging agents |
JP5063603B2 (ja) * | 2005-09-30 | 2012-10-31 | クック メディカル テクノロジーズ エルエルシー | 被覆された血管閉塞装置 |
US7479784B2 (en) | 2005-10-12 | 2009-01-20 | New York University | Arrangements, systems and methods for facilitating and collecting information associated with fluxes of magnetic fields provided at various angles from one another |
WO2007053533A2 (en) | 2005-11-01 | 2007-05-10 | Wyeth | Sodium chloride solution for drug reconstitution or dilution |
US8193804B2 (en) | 2005-11-16 | 2012-06-05 | Rex Chin-Yih Hong | Device for measuring AC magnetization of materials |
US7702378B2 (en) | 2005-11-17 | 2010-04-20 | Breast-Med, Inc. | Tissue marker for multimodality radiographic imaging |
US8078260B2 (en) | 2006-05-02 | 2011-12-13 | ORGAMEND Inc. | Method for improving magnetic resonance imaging of the breast |
WO2008051749A2 (en) | 2006-10-23 | 2008-05-02 | C. R. Bard, Inc. | Breast marker |
US20090024022A1 (en) | 2006-10-25 | 2009-01-22 | Siemens Corporate Research, Inc. | System and method for lymph node imaging using co-registration of ct and mr imagery |
US20080124281A1 (en) * | 2006-11-29 | 2008-05-29 | Board Of Regents, The University Of Texas System | Nanotubular probes as ultrasensitive mr contrast agent |
US20080146914A1 (en) | 2006-12-19 | 2008-06-19 | General Electric Company | System, method and apparatus for cancer imaging |
DE102007009016A1 (de) | 2007-02-23 | 2008-08-28 | Siemens Ag | Markierung und Verfahren zur Positionsbestimmung eines Zielgewebes |
US20080228164A1 (en) | 2007-03-14 | 2008-09-18 | Nicoson Zachary R | Implant delivery system |
US20080255425A1 (en) | 2007-04-13 | 2008-10-16 | Ethicon Endo-Surgery, Inc. | Nanoparticle treated medical devices |
WO2008131391A1 (en) | 2007-04-23 | 2008-10-30 | Device Evolutions, Llc | Surgical metal detection apparatus and methods |
US8137320B2 (en) | 2007-05-01 | 2012-03-20 | Suros Surgical Systems, Inc. | Securement for a surgical site marker and deployment device for same |
US9763597B2 (en) | 2007-05-03 | 2017-09-19 | Wisconsin Alumni Research Foundation | Local MRI breast coil and method of use |
US20090082662A1 (en) | 2007-09-24 | 2009-03-26 | Israel Henry M | Mri breast image magnet structure |
DE102007046186A1 (de) | 2007-09-26 | 2009-04-02 | Amedo Smart Tracking Solutions Gmbh | Gewebemarkierung |
US8731635B2 (en) | 2007-11-07 | 2014-05-20 | University of Pittsburgh—of the Commonwealth System of Higher Education | Coils for magnetic resonance spectroscopy and imaging of human breast |
WO2009103938A1 (en) * | 2008-02-22 | 2009-08-27 | University Of Exeter | Controllable magnetic systems |
DE102008015781B4 (de) * | 2008-03-26 | 2011-09-29 | Malte Neuss | Vorrichtung zum Verschluss von Defekten im Gefäßsystem |
US8050742B2 (en) | 2008-07-30 | 2011-11-01 | Devicor Medical Products, Inc. | Biopsy device |
DE102008048291B4 (de) | 2008-09-22 | 2012-02-16 | Siemens Aktiengesellschaft | Brustspulenanordnung für Magnetresonanzanwendungen |
GB2465771A (en) | 2008-11-28 | 2010-06-02 | Helyn Margaret Wright | Surgical Localisation Device |
AU2010265891B2 (en) | 2009-06-26 | 2016-06-23 | Cianna Medical, Inc. | Apparatus, systems, and methods for localizing markers or tissue structures within a body |
GB0916334D0 (en) | 2009-09-17 | 2009-10-28 | Renovo Ltd | Inhibition of tendon adhesions |
US10634741B2 (en) | 2009-12-04 | 2020-04-28 | Endomagnetics Ltd. | Magnetic probe apparatus |
US9427186B2 (en) | 2009-12-04 | 2016-08-30 | Endomagnetics Ltd. | Magnetic probe apparatus |
JP5678565B2 (ja) | 2009-12-08 | 2015-03-04 | Jnc株式会社 | 磁性微粒子およびその製造方法 |
US8870898B2 (en) | 2010-01-05 | 2014-10-28 | GI Windows, Inc. | Self-assembling magnetic anastomosis device having an exoskeleton |
DE102011081445A1 (de) * | 2011-08-23 | 2013-02-28 | Epflex Feinwerktechnik Gmbh | Medizinischer Führungsdraht und Herstellungsverfahren |
US8798716B1 (en) | 2011-11-03 | 2014-08-05 | Solstice Corporation | Fiducial markers and related methods |
EP2809256B1 (en) | 2012-02-01 | 2017-07-12 | Koninklijke Philips N.V. | Multimodal fiducial marker and marker arrangement |
BR112015022129B1 (pt) | 2013-03-11 | 2022-04-19 | Endomagnetics Ltd | Soluções hiposmóticas para a detecção de linfonodo |
JP6305869B2 (ja) * | 2014-08-19 | 2018-04-04 | 日立建機株式会社 | 建設機械用エンジン制御装置 |
-
2016
- 2016-06-03 KR KR1020187000167A patent/KR102589814B1/ko active IP Right Grant
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Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002004118A (ja) * | 2000-06-21 | 2002-01-09 | Unitika Ltd | 徘徊患者用衣服 |
US20080097199A1 (en) * | 2004-08-20 | 2008-04-24 | David Mullen | Tissue Marking Devices and Systems |
JP2008143896A (ja) * | 2006-11-21 | 2008-06-26 | Suros Surgical Systems Inc | 複数の物理療法で視認可能な部位マーカー |
JP2012177691A (ja) * | 2011-02-04 | 2012-09-13 | Hitachi Maxell Ltd | 磁性マーカー粒子 |
JP2013085642A (ja) * | 2011-10-17 | 2013-05-13 | Tokyo Denki Univ | 医療用チューブの先端位置検出システムおよび当該システムに適用する医療用チューブ |
US20140018663A1 (en) * | 2012-07-16 | 2014-01-16 | Endomagnetics Ltd. | Magnetic Marker for Surgical Localization |
WO2014013235A1 (en) * | 2012-07-16 | 2014-01-23 | Endomagnetics Ltd | Magnetic marker for surgical localization |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021005955A1 (ja) * | 2019-07-10 | 2021-01-14 | 京都府公立大学法人 | 医療用イメージガイダンスマーカー |
JPWO2021005955A1 (ja) * | 2019-07-10 | 2021-01-14 | ||
JP7273428B2 (ja) | 2019-07-10 | 2023-05-15 | 京都府公立大学法人 | 医療用イメージガイダンスマーカー |
WO2023007702A1 (ja) * | 2021-07-30 | 2023-02-02 | 株式会社マトリックス細胞研究所 | 磁性マーカセット、磁性マーカ配置方法 |
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CN113558782A (zh) | 2021-10-29 |
EP3302338A2 (en) | 2018-04-11 |
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AU2016272550B2 (en) | 2021-01-28 |
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KR102589814B1 (ko) | 2023-10-13 |
CN107920865A (zh) | 2018-04-17 |
CA2988065C (en) | 2024-03-26 |
EP4085866A2 (en) | 2022-11-09 |
US11504207B2 (en) | 2022-11-22 |
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CA2988065A1 (en) | 2016-12-08 |
EP3782575A1 (en) | 2021-02-24 |
KR20180015234A (ko) | 2018-02-12 |
MX2017015588A (es) | 2018-04-13 |
JP6821665B2 (ja) | 2021-01-27 |
ES2833377T3 (es) | 2021-06-15 |
CN107920865B (zh) | 2021-07-09 |
AU2016272550A1 (en) | 2018-01-18 |
EP4085866A3 (en) | 2023-01-18 |
WO2016193753A3 (en) | 2017-01-12 |
US20160354178A1 (en) | 2016-12-08 |
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