JP2015513557A5 - - Google Patents

Download PDF

Info

Publication number
JP2015513557A5
JP2015513557A5 JP2014561064A JP2014561064A JP2015513557A5 JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5 JP 2014561064 A JP2014561064 A JP 2014561064A JP 2014561064 A JP2014561064 A JP 2014561064A JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5
Authority
JP
Japan
Prior art keywords
agent according
therapeutic agent
pain
peripheral neuropathy
neuropathic pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014561064A
Other languages
English (en)
Other versions
JP2015513557A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/029258 external-priority patent/WO2013134336A2/en
Publication of JP2015513557A publication Critical patent/JP2015513557A/ja
Publication of JP2015513557A5 publication Critical patent/JP2015513557A5/ja
Pending legal-status Critical Current

Links

Claims (4)

  1. アダプター関連キナーゼ１（ＡＡＫ１）阻害剤を含む、疼痛を治療又は管理するための治療剤。
  2. 前記疼痛が神経因性疼痛である、請求項１に記載の治療剤。
  3. 前記神経因性疼痛が線維筋痛又は末梢神経障害である、請求項２に記載の治療剤。
  4. 前記末梢神経障害が糖尿病性神経障害である、請求項３に記載の治療剤。
JP2014561064A 2012-03-09 2013-03-06 疼痛の治療に対するアダプター関連キナーゼ１の阻害 Pending JP2015513557A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261608849P 2012-03-09 2012-03-09
US61/608,849 2012-03-09
PCT/US2013/029258 WO2013134336A2 (en) 2012-03-09 2013-03-06 Inhibition of adaptor associated kinase 1 for the treatment of pain

Publications (2)

Publication Number Publication Date
JP2015513557A JP2015513557A (ja) 2015-05-14
JP2015513557A5 true JP2015513557A5 (ja) 2016-04-21

Family

ID=47884616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014561064A Pending JP2015513557A (ja) 2012-03-09 2013-03-06 疼痛の治療に対するアダプター関連キナーゼ１の阻害

Country Status (14)

Country Link
US (4) US20140080834A1 (ja)
EP (2) EP3235499A3 (ja)
JP (1) JP2015513557A (ja)
CN (1) CN104220071A (ja)
AU (1) AU2013230066A1 (ja)
CA (1) CA2866145A1 (ja)
DK (1) DK2822555T3 (ja)
ES (1) ES2657061T3 (ja)
HK (1) HK1199814A1 (ja)
HU (1) HUE036040T2 (ja)
NO (1) NO2935475T3 (ja)
PL (1) PL2822555T3 (ja)
PT (1) PT2822555T (ja)
WO (1) WO2013134336A2 (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102085121B1 (ko) 2012-03-09 2020-03-05 렉시컨 파마슈티컬스 인코퍼레이티드 이미다조[1,2-b]피리다진계 화합물, 그를 포함하는 조성물 및 그의 용도
RU2014140735A (ru) 2012-03-09 2016-04-27 Лексикон Фармасьютикалз, Инк. ПРОИЗВОДНЫЕ ПИРАЗОЛО[1, 5-a]ПИРИМИДИНА, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ СОЕДИНЕНИЯ, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
US8901305B2 (en) 2012-07-31 2014-12-02 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
CN105121445A (zh) 2013-02-22 2015-12-02 百时美施贵宝公司 作为连接蛋白相关激酶1(AAK1)抑制剂的5H-色烯并[3,4-c]吡啶
WO2014175370A1 (ja) * 2013-04-25 2014-10-30 塩野義製薬株式会社 ピロリジン誘導体およびそれらを含有する医薬組成物
EP3016951B1 (en) * 2013-07-02 2017-05-31 Bristol-Myers Squibb Company Tricyclic pyrido-carboxamide derivatives as rock inhibitors
US10253027B2 (en) 2013-07-08 2019-04-09 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
TW201542550A (zh) 2013-09-06 2015-11-16 Lexicon Pharmaceuticals Inc 吡唑并［１，５－ａ］嘧啶基化合物、包含彼之組合物以及使用彼之方法
WO2015038112A1 (en) * 2013-09-11 2015-03-19 Bristol-Myers Squibb Company Aryl ether-base kinase inhibitors
EP3054955B1 (en) * 2013-10-11 2018-05-30 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
JP6441947B2 (ja) * 2014-01-31 2018-12-19 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ キノリンを基にしたキナーゼ阻害剤
TW201620911A (zh) * 2014-03-17 2016-06-16 雷西肯製藥股份有限公司 銜接子關聯激酶１之抑制劑、包含其之組成物、及其使用方法
CA2944466C (en) * 2014-04-02 2020-06-09 Bristol-Myers Squibb Company Biaryl kinase inhibitors
WO2016022312A1 (en) * 2014-08-05 2016-02-11 Bristol-Myers Squibb Company Heterocyclic kinase inhibitors
PT3215511T (pt) 2014-11-06 2024-05-22 Bial R&D Invest S A Pirazolo(1,5-a)pirimidinas substituídas e a sua utilização no tratamento de distúrbios médicos
EP3292124B1 (en) 2015-04-10 2019-05-22 Bristol-Myers Squibb Company 6h-isochromeno[3,4-c]pyridines and benzo[c][1,7]naphthyridin-6-(5h)-ones as adaptor associated kinase 1 (aak1) inhibitors
US10246469B2 (en) 2015-10-01 2019-04-02 Bristol-Myers Squibb Company Biaryl kinase inhibitors
CN112142655A (zh) 2015-10-01 2020-12-29 百时美施贵宝公司 联芳基激酶抑制剂
CA3020305A1 (en) 2016-04-06 2017-10-12 Lysosomal Therapeutics Inc. Imidazo [1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
AU2017246455B2 (en) 2016-04-06 2021-09-30 Bial - R&D Investments, S.A. Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
WO2017192930A1 (en) * 2016-05-05 2017-11-09 Lysosomal Therapeutics Inc. SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
WO2018013430A2 (en) 2016-07-12 2018-01-18 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus infection
KR102590444B1 (ko) * 2020-10-16 2023-10-18 김홍렬 Pmca 억제제를 포함하는 코로나바이러스 감염 또는 감염 질환의 치료용 조성물
KR102590438B1 (ko) * 2020-10-16 2023-10-18 김홍렬 Pmca 억제제를 포함하는 코로나바이러스 감염 또는 감염 질환의 예방 또는 소독용 조성물
WO2023196584A2 (en) * 2022-04-08 2023-10-12 New York University Endocytosis inhibitors and their use for pain treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
WO1993004169A1 (en) 1991-08-20 1993-03-04 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
WO2007025090A2 (en) * 2005-08-25 2007-03-01 Kalypsys, Inc. Heterobicyclic and - tricyclic inhibitors of mapk/erk kinase
MX2009004715A (es) * 2006-10-30 2009-05-20 Novartis Ag Compuestos heterociclicos como agentes antiinflamatorios.
EP2300469B1 (en) * 2008-05-13 2015-06-24 Novartis AG Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors
US8461336B2 (en) * 2008-09-04 2013-06-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules

Similar Documents

Publication Publication Date Title
JP2015513557A5 (ja)
JP2017506627A5 (ja)
JP2015503422A5 (ja)
JP2015528502A5 (ja)
EP3307738A4 (en) ARYL-DIHYDRO-2H-BENZO [B] [1,4] OXAZINE-SULPHONAMIDE AND RELATED COMPOUNDS FOR USE AS AGENTS OF RORY AND FOR THE TREATMENT OF DISEASES
JP2016139345A5 (ja)
JP2014530840A5 (ja)
EP3292119A4 (en) DIHYDRO-2H-BENZO[b][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE
CA2929436C (en) Compounds, pharmaceutical composition and methods for use in treating inflammatory diseases
JP2013231052A5 (ja)
CL2008000110A1 (es) Uso de compuestos derivados de piranona sustituidos para el tratamiento del sindrome metabolico; y compuestos derivados de piranona sustituidos.
JP2015173751A5 (ja)
WO2015066302A3 (en) Compositions, methods of use, and methods of treatment
JP2017531686A5 (ja)
EA201790687A1 (ru) Хинолинкарбоксамиды для применения в лечении множественной миеломы
EA201692518A3 (ru) Способы улучшения производительности миокарда у пациентов после операции фонтена с применением композиций уденафила
JP2015016294A5 (ja)
JP2015005289A5 (ja)
WO2014180882A3 (en) Treatment of brain metastasis from cancer
BR112014017493A2 (pt) usos terapêuticos
JP2017014205A5 (ja)
ES2525079A1 (es) Actividad antiparasitaria de escuaramidas
JP2015525770A5 (ja)
UA114966U (xx) Застосування натрієвої солі [полі-(2,5-дигідроксифенілен)]-4-тіосульфокислоти для лікування гострого пошкодження нирок
ICHIE The Beginning of Music & Acoustical Medicine