JP2005518789A5 - - Google Patents
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- JP2005518789A5 JP2005518789A5 JP2003564202A JP2003564202A JP2005518789A5 JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5 JP 2003564202 A JP2003564202 A JP 2003564202A JP 2003564202 A JP2003564202 A JP 2003564202A JP 2005518789 A5 JP2005518789 A5 JP 2005518789A5
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- JP
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- Prior art keywords
- antibody
- psma
- seq
- region
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Images
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5998902A | 2002-01-28 | 2002-01-28 | |
PCT/US2003/002448 WO2003064606A2 (fr) | 2002-01-28 | 2003-01-28 | Anticorps monoclonaux humains de l'antigene d'enveloppe prostatique specifique (psma) |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005518789A JP2005518789A (ja) | 2005-06-30 |
JP2005518789A5 true JP2005518789A5 (fr) | 2006-03-02 |
Family
ID=27658271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003564202A Pending JP2005518789A (ja) | 2002-01-28 | 2003-01-28 | 前立腺特異性膜抗原(psma)に対するヒトモノクローナル抗体 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1519747A4 (fr) |
JP (1) | JP2005518789A (fr) |
KR (1) | KR20040077889A (fr) |
CN (1) | CN1652821A (fr) |
AU (1) | AU2003224604B2 (fr) |
BR (1) | BR0307216A (fr) |
CA (1) | CA2474616A1 (fr) |
MX (1) | MXPA04007262A (fr) |
NZ (1) | NZ534687A (fr) |
WO (1) | WO2003064606A2 (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
US6569432B1 (en) | 1995-02-24 | 2003-05-27 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
US7381407B1 (en) | 1996-03-25 | 2008-06-03 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US6962981B1 (en) | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
ES2559002T3 (es) | 2001-10-23 | 2016-02-10 | Psma Development Company, L.L.C. | Anticuerpos contra PSMA |
US20050191293A1 (en) * | 2003-12-10 | 2005-09-01 | Shrikant Deshpande | IP-10 antibodies and their uses |
EP1766093B1 (fr) * | 2004-02-06 | 2011-06-15 | University of Massachusetts | Anticorps diriges contre des toxines de clostridium difficile et utilisations de ces derniers |
JP4734319B2 (ja) * | 2004-03-19 | 2011-07-27 | イムクローン・リミテッド・ライアビリティ・カンパニー | ヒト抗上皮成長因子受容体抗体 |
CA2885854C (fr) | 2004-04-13 | 2017-02-21 | F. Hoffmann-La Roche Ag | Anticorps anti-p-selectine |
EP1791868B1 (fr) | 2004-07-01 | 2011-02-23 | Novo Nordisk A/S | Anticorps liant a des recepteurs kir2dl1,-2,-3, sauf kir2ds4 et leur usage therapeutique |
EP1836225B1 (fr) | 2005-01-06 | 2011-11-02 | Novo Nordisk A/S | Agents de liaison kir et leurs procedes d'utilisation |
US7875278B2 (en) | 2005-02-18 | 2011-01-25 | Medarex, Inc. | Monoclonal antibodies against prostate specific membrane antigen (PSMA) lacking in fucosyl residues |
CN101124249B (zh) * | 2005-02-18 | 2011-06-29 | 米德列斯公司 | 抗***特异性膜抗原(psma)的人单克隆抗体 |
CA2970873C (fr) * | 2005-05-09 | 2022-05-17 | E. R. Squibb & Sons, L.L.C. | Anticorps monoclonaux humains pour mort programmee 1 (mp-1) et procedes pour traiter le cancer en utilisant des anticorps anti-mp-1 seuls ou associes a d'autres immunotherapies |
EP1726650A1 (fr) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Anticorps monoclonaux et fragments d'anticorps monocaténaires contre l'antigène spécifique de surface membranaire de la prostate |
ES2397973T3 (es) * | 2006-03-14 | 2013-03-12 | Cancer Targeted Technology Llc | Inhibidores peptidomiméticos del PSMA, compuestos que los comprenden y métodos de utilización |
US8852630B2 (en) | 2008-05-13 | 2014-10-07 | Yale University | Chimeric small molecules for the recruitment of antibodies to cancer cells |
DK2326350T3 (da) | 2008-09-08 | 2013-12-16 | Psma Dev Company L L C | Forbindelser til at dræbe psma-udtrykkende, taxanresistente cancerceller |
NZ591134A (en) * | 2008-10-01 | 2012-08-31 | Micromet Ag | Cross-species-specific (human and primate) bispecific single chain antibody that binds both cd3 (epsilon) epitope and prostate specific membrane antigen (pmsa) |
CN101891818B (zh) * | 2009-01-16 | 2012-07-25 | 中国人民解放军第四军医大学 | 抗人***特异性膜抗原胞外区单链抗体及其应用 |
EP2419451A4 (fr) * | 2009-04-14 | 2012-11-14 | Proscan Rx Pharma Inc | Anticorps dirigés contre l'antigène membranaire spécifique de la prostate |
CN103561771B (zh) | 2011-03-17 | 2019-01-04 | 伯明翰大学 | 重新定向的免疫治疗 |
CA2833019A1 (fr) | 2011-04-22 | 2012-10-26 | Emergent Product Development Seattle, Llc | Proteines de liaison a un antigene membranaire specifique de la prostate et compositions et procedes associes |
RS53818B1 (en) | 2012-10-12 | 2015-06-30 | Spirogen Sàrl | PIROLOBENZODIAZEPINI I NJIHOVI conjugated |
CA2905181C (fr) | 2013-03-13 | 2020-06-02 | Medimmune Limited | Pyrrolobenzodiazepines et ses conjugues servant a fournir une therapie ciblee |
CN103333249A (zh) * | 2013-06-14 | 2013-10-02 | 广州康合生物科技有限公司 | 一种抗***特异性膜抗原(psma)的单克隆抗体及其应用 |
WO2016037644A1 (fr) | 2014-09-10 | 2016-03-17 | Medimmune Limited | Pyrrolobenzodiazépines et leurs conjugués |
US10100126B2 (en) * | 2015-03-10 | 2018-10-16 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind PSMA |
ES2889906T3 (es) | 2015-05-21 | 2022-01-14 | Harpoon Therapeutics Inc | Proteínas de unión triespecíficas y usos médicos |
WO2017053469A2 (fr) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Polypeptides de liaison à cd3 |
KR101704379B1 (ko) * | 2015-10-27 | 2017-02-08 | (주)알테오젠 | 항체-약물 접합체 및 그 제조방법 |
WO2017164678A2 (fr) * | 2016-03-23 | 2017-09-28 | 서울대학교산학협력단 | Anticorps qui se lie à la protéine d'enveloppe du virus du syndrome de fièvre sévère avec thrombocytopénie, et son utilisation |
WO2017201488A1 (fr) | 2016-05-20 | 2017-11-23 | Harpoon Therapeutics, Inc. | Protéine de liaison à l'albumine sérique à domaine unique |
KR102365977B1 (ko) | 2016-05-20 | 2022-02-22 | 하푼 테라퓨틱스, 인크. | 단일 쇄 가변 단편 cd3 결합 단백질 |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
WO2018069289A1 (fr) | 2016-10-11 | 2018-04-19 | Medimmune Limited | Conjugués anticorps-médicament associés à des agents thérapeutiques à médiation immunitaire |
CA3044659A1 (fr) | 2016-11-23 | 2018-05-31 | Harpoon Therapeutics, Inc. | Proteine de liaison a l'antigene membranaire specifique de la prostate |
BR112019010602A2 (pt) * | 2016-11-23 | 2019-12-17 | Harpoon Therapeutics Inc | proteínas trispecíficas para psma e métodos de uso |
EP3589662A4 (fr) | 2017-02-28 | 2020-12-30 | Harpoon Therapeutics, Inc. | Protéine monovalente inductible de fixation d' antigène |
JP7090347B2 (ja) | 2017-05-12 | 2022-06-24 | ハープーン セラピューティクス,インク. | メソテリン結合タンパク質 |
CA3063362A1 (fr) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Proteines trispecifiques ciblant la msln et procedes d'utilisation |
BR112020007196A2 (pt) | 2017-10-13 | 2020-12-01 | Harpoon Therapeutics, Inc. | proteínas triespecíficas e métodos de uso |
CR20200195A (es) | 2017-10-13 | 2020-08-14 | Harpoon Therapeutics Inc | Proteínas de unión a antigenos de maduraciòn de celulas b |
WO2019224275A1 (fr) | 2018-05-23 | 2019-11-28 | Adc Therapeutics Sa | Adjuvant moléculaire |
US10815311B2 (en) | 2018-09-25 | 2020-10-27 | Harpoon Therapeutics, Inc. | DLL3 binding proteins and methods of use |
JP2022514262A (ja) | 2018-12-17 | 2022-02-10 | レビトープ リミテッド | 双子型免疫細胞エンゲージャー |
WO2021164692A1 (fr) * | 2020-02-18 | 2021-08-26 | 和铂医药(上海)有限责任公司 | Protéine isolée se liant à l'antigène psma et son utilisation |
CN115768463A (zh) | 2020-02-21 | 2023-03-07 | 哈普恩治疗公司 | Flt3结合蛋白及使用方法 |
WO2022079211A1 (fr) | 2020-10-16 | 2022-04-21 | Adc Therapeutics Sa | Glycoconjugués |
GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
US20230201366A1 (en) | 2021-11-19 | 2023-06-29 | Adc Therapeutics Sa | Anti-psma conjugates |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69426527T2 (de) * | 1993-06-09 | 2001-08-30 | Unilever Nv | Verfahren zur herstellung von fusionsproteinen, die scfv fragmente enthalten, in transformierten schimmelpilzen |
US7563874B2 (en) * | 1998-08-31 | 2009-07-21 | The Regents Of The University Of California | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
ES2277846T3 (es) * | 1999-07-29 | 2007-08-01 | Medarex, Inc. | Anticuerpos monoclonales humanos para antigeno prostatico especifico. |
GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
NZ522700A (en) * | 2000-06-16 | 2006-02-24 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to blys |
ES2559002T3 (es) * | 2001-10-23 | 2016-02-10 | Psma Development Company, L.L.C. | Anticuerpos contra PSMA |
AU2003270010A1 (en) * | 2002-08-30 | 2004-03-19 | Biorexis Pharmaceutical Corporation | Transferrin fusion protein libraries |
CA2508214A1 (fr) * | 2002-12-02 | 2004-06-17 | Abgenix, Inc. | Anticorps diriges contre la phospholipase a2 et utilisations |
-
2003
- 2003-01-28 KR KR10-2004-7011643A patent/KR20040077889A/ko not_active Application Discontinuation
- 2003-01-28 JP JP2003564202A patent/JP2005518789A/ja active Pending
- 2003-01-28 AU AU2003224604A patent/AU2003224604B2/en not_active Ceased
- 2003-01-28 WO PCT/US2003/002448 patent/WO2003064606A2/fr active IP Right Grant
- 2003-01-28 EP EP03721280A patent/EP1519747A4/fr not_active Withdrawn
- 2003-01-28 BR BR0307216-9A patent/BR0307216A/pt not_active IP Right Cessation
- 2003-01-28 CN CNA038073714A patent/CN1652821A/zh active Pending
- 2003-01-28 NZ NZ534687A patent/NZ534687A/en unknown
- 2003-01-28 MX MXPA04007262A patent/MXPA04007262A/es unknown
- 2003-01-28 CA CA002474616A patent/CA2474616A1/fr not_active Abandoned
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