IT8068555A0 - Derivati di 1 2 4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Derivati di 1 2 4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT8068555A0 IT8068555A0 IT8068555A IT6855580A IT8068555A0 IT 8068555 A0 IT8068555 A0 IT 8068555A0 IT 8068555 A IT8068555 A IT 8068555A IT 6855580 A IT6855580 A IT 6855580A IT 8068555 A0 IT8068555 A0 IT 8068555A0
- Authority
- IT
- Italy
- Prior art keywords
- oxadiazolin
- derivatives
- procedure
- contain
- preparation
- Prior art date
Links
- JKNSMBZZZFGYCB-UHFFFAOYSA-N 4,5-dihydrooxadiazole Chemical compound C1CN=NO1 JKNSMBZZZFGYCB-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
- C07D273/04—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU79CI1973A HU179951B (en) | 1979-10-11 | 1979-10-11 | Process for preparing 1,2,4-oxadiazolin-5-one derivatives and pharmaceutical compositions containing thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8068555A0 true IT8068555A0 (it) | 1980-10-09 |
| IT1129305B IT1129305B (it) | 1986-06-04 |
Family
ID=10994764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT68555/80A IT1129305B (it) | 1979-10-11 | 1980-10-09 | Derivati di 1,2,4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4365064A (it) |
| JP (1) | JPS5661375A (it) |
| AT (1) | AT375369B (it) |
| BE (1) | BE885633A (it) |
| CA (1) | CA1154019A (it) |
| CH (1) | CH649547A5 (it) |
| CS (1) | CS241032B2 (it) |
| DD (1) | DD153550A5 (it) |
| DE (1) | DE3037432A1 (it) |
| DK (1) | DK149854C (it) |
| ES (1) | ES495819A0 (it) |
| FI (2) | FI71318C (it) |
| FR (1) | FR2467203A1 (it) |
| GB (1) | GB2059967B (it) |
| HU (1) | HU179951B (it) |
| IL (1) | IL61175A (it) |
| IT (1) | IT1129305B (it) |
| NL (1) | NL8005586A (it) |
| NO (1) | NO154795C (it) |
| PL (3) | PL132131B1 (it) |
| SE (1) | SE452158B (it) |
| SU (1) | SU1087519A1 (it) |
| YU (1) | YU41738B (it) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU180708B (en) * | 1979-10-11 | 1983-04-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new 1,2,4-oxadiazine derivatives |
| NZ521792A (en) * | 2000-03-20 | 2004-06-25 | N Gene Res Lab Inc | Propenecarboxylic acid amidoxime derivatives, a process for the preparation thereof, and use in treating conditions connected with oxygen deficiency |
| JP2016505000A (ja) | 2012-12-21 | 2016-02-18 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
| US9365555B2 (en) * | 2012-12-21 | 2016-06-14 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| JP2016505597A (ja) | 2012-12-21 | 2016-02-25 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
| DK2935222T3 (en) | 2012-12-21 | 2019-01-07 | Epizyme Inc | PRMT5 INHIBITORS AND APPLICATIONS THEREOF |
| US9745291B2 (en) | 2012-12-21 | 2017-08-29 | Epizyme, Inc. | PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
| JP2017530940A (ja) | 2014-08-04 | 2017-10-19 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1529700A (fr) * | 1967-04-11 | 1968-06-21 | Dausse Sa Lab | Tertioaminoalcoyl oxadiazolinones et leur procédé de préparation |
| FR1575552A (it) * | 1967-12-07 | 1969-07-25 | ||
| US4038279A (en) * | 1972-12-23 | 1977-07-26 | Boehringer Ingelheim Gmbh | N-aryl-n'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof |
| US3994891A (en) * | 1974-12-20 | 1976-11-30 | Armour Pharmaceutical Company | Tetrahydroisoquinoline compounds |
| US4187220A (en) * | 1977-08-30 | 1980-02-05 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same |
| HU180708B (en) * | 1979-10-11 | 1983-04-29 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new 1,2,4-oxadiazine derivatives |
-
1979
- 1979-10-11 HU HU79CI1973A patent/HU179951B/hu not_active IP Right Cessation
-
1980
- 1980-09-30 IL IL61175A patent/IL61175A/xx unknown
- 1980-10-03 DE DE19803037432 patent/DE3037432A1/de not_active Withdrawn
- 1980-10-06 CS CS806737A patent/CS241032B2/cs unknown
- 1980-10-07 SE SE8007025A patent/SE452158B/sv not_active IP Right Cessation
- 1980-10-09 IT IT68555/80A patent/IT1129305B/it active
- 1980-10-09 FR FR8021624A patent/FR2467203A1/fr active Granted
- 1980-10-09 AT AT0501380A patent/AT375369B/de not_active IP Right Cessation
- 1980-10-09 JP JP14066880A patent/JPS5661375A/ja active Pending
- 1980-10-09 NL NL8005586A patent/NL8005586A/nl not_active Application Discontinuation
- 1980-10-10 SU SU802993201A patent/SU1087519A1/ru active
- 1980-10-10 FI FI803219A patent/FI71318C/fi not_active IP Right Cessation
- 1980-10-10 DK DK429780A patent/DK149854C/da not_active IP Right Cessation
- 1980-10-10 YU YU2594/80A patent/YU41738B/xx unknown
- 1980-10-10 GB GB8032828A patent/GB2059967B/en not_active Expired
- 1980-10-10 FI FI803220A patent/FI71932C/fi not_active IP Right Cessation
- 1980-10-10 BE BE0/202406A patent/BE885633A/fr not_active IP Right Cessation
- 1980-10-10 PL PL1980232293A patent/PL132131B1/pl unknown
- 1980-10-10 PL PL1980232292A patent/PL131451B1/pl unknown
- 1980-10-10 DD DD80224478A patent/DD153550A5/de not_active IP Right Cessation
- 1980-10-10 CA CA000362217A patent/CA1154019A/en not_active Expired
- 1980-10-10 CH CH7599/80A patent/CH649547A5/de not_active IP Right Cessation
- 1980-10-10 PL PL1980227209A patent/PL131375B1/pl unknown
- 1980-10-10 NO NO803044A patent/NO154795C/no unknown
- 1980-10-10 ES ES495819A patent/ES495819A0/es active Granted
- 1980-10-14 US US06/196,583 patent/US4365064A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT8167311A0 (it) | Derivati carbostirilici procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali derivati | |
| IT1109339B (it) | Procedimento per la preparazione di derivati amminici e composizioni farmaceutiche che li contengono e prodotto ottenuto | |
| IT8168316A0 (it) | Derivati di polietilen glicoli procedimento per la loro preparazione ed impiego e composizioni che licontengono | |
| IT8567757A0 (it) | Derivati di benzonorbornene procedimento per la loro preparazione e composizioni medicinali e cosmetiche che li contengono | |
| IT1224226B (it) | Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono | |
| IT1129933B (it) | Derivati tioetilammidici loro composizioni farmaceutiche e procedimento per la loro preparazione | |
| IT1156490B (it) | Derivati carbostirilici procedimento per la loro preparazione e composizioni carditoniche contenenti tali derivati | |
| IT1114720B (it) | Procedimento per la preparazione di derivati di 2-fenilimmino-imidazolidine composizioni farmaceutiche che li contengono e prodotto ottenuto | |
| IT8068555A0 (it) | Derivati di 1 2 4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
| IT7948266A0 (it) | Procedimento per la preparazione di derivati di bicicloottano e di composizioni farmaceutiche che li con tengono e prodotto ottenuto | |
| IT7850986A0 (it) | 5-imminodaunomicina e suoi derivati procedimento per prepararla nonche'composizioni farmaceutiche che la contengono | |
| IT1147741B (it) | Derivati di idrossiammino eburnano e procedimento per la loro preparazione | |
| IT1132403B (it) | Derivati di alovincamone e procedimento per la loro preparazione | |
| IT8667976A0 (it) | Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono | |
| IT8667809A0 (it) | Derivati di 2 1 2 4 triazolin 5 one procedimento per la loro preparazione composizioni che li contengono e relativi impieghi | |
| IT1168766B (it) | Derivati di piperazina e di omopipe razina,procedimenti per la loro preparazione e composizioni farmaceutiche che li contengono | |
| IT1227456B (it) | Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono | |
| IT1146725B (it) | Derivati dell 1 benzilimidazolo procedimento per la loro preparazione e composizione farmaceutica e composizione fungicida che li contengono | |
| IT1164697B (it) | Procedimento per la preparazione di derivati acetilenici di androst-4-ene e composizioni farmaceutiche che li contengono e prodotto uttenuto | |
| IT8048308A0 (it) | Derivati benzotiazolici procedimento per prepararli e composizioni farmaceutiche che li contengono | |
| IT1132404B (it) | Derivati di 10-alo-e-omoeburnano e procedimento per la loro preparazione | |
| IT8024152A0 (it) | Derivati dell'1,1,2-trifenilpropano e dell'1,1,2-trifenilpropene, procedimento per la loro preparazione e composizioni farmaceutiche contenenti i composti | |
| IT7950600A0 (it) | Derivati eterociclici di cumarina procedimento per prepararli e composizioni farmaceutiche che li contengono | |
| IT1133085B (it) | Derivati dialogenati geminali di composti condensati del pirimidin 4 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
| IT8068556A0 (it) | Derivati della 1 2 4 ossadiazina procedimento per la loro preparazione e composizioni farmaceutiche cheli contengono |