IT1318463B1 - Procedimento per la preparazione di 5'-acetilstavudina. - Google Patents

Procedimento per la preparazione di 5'-acetilstavudina.

Info

Publication number
IT1318463B1
IT1318463B1 IT2000MI000810A ITMI20000810A IT1318463B1 IT 1318463 B1 IT1318463 B1 IT 1318463B1 IT 2000MI000810 A IT2000MI000810 A IT 2000MI000810A IT MI20000810 A ITMI20000810 A IT MI20000810A IT 1318463 B1 IT1318463 B1 IT 1318463B1
Authority
IT
Italy
Prior art keywords
preparation
acetilstavudina
procedure
acetylstavudine
didehydro
Prior art date
Application number
IT2000MI000810A
Other languages
English (en)
Inventor
Giorgio Bertolini
Marco Frigerio
Luigi Petrucciani
Maurizio Velati
Original Assignee
Archimica S P A Ora Clariant L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimica S P A Ora Clariant L filed Critical Archimica S P A Ora Clariant L
Publication of ITMI20000810A0 publication Critical patent/ITMI20000810A0/it
Priority to IT2000MI000810A priority Critical patent/IT1318463B1/it
Priority to EP01917385A priority patent/EP1274704B1/en
Priority to MXPA02010072A priority patent/MXPA02010072A/es
Priority to JP2001575576A priority patent/JP2003530394A/ja
Priority to DE60101791T priority patent/DE60101791T2/de
Priority to KR1020027011340A priority patent/KR100800650B1/ko
Priority to ES01917385T priority patent/ES2213109T3/es
Priority to PCT/IB2001/000588 priority patent/WO2001077103A1/en
Priority to BR0109965-5A priority patent/BR0109965A/pt
Priority to HU0300259A priority patent/HUP0300259A3/hu
Priority to AT01917385T priority patent/ATE257835T1/de
Priority to US09/834,028 priority patent/US6350873B2/en
Publication of ITMI20000810A1 publication Critical patent/ITMI20000810A1/it
Application granted granted Critical
Publication of IT1318463B1 publication Critical patent/IT1318463B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IT2000MI000810A 2000-04-12 2000-04-12 Procedimento per la preparazione di 5'-acetilstavudina. IT1318463B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT2000MI000810A IT1318463B1 (it) 2000-04-12 2000-04-12 Procedimento per la preparazione di 5'-acetilstavudina.
ES01917385T ES2213109T3 (es) 2000-04-12 2001-04-10 Procedimiento para preparar 5'-acetilestavudina.
BR0109965-5A BR0109965A (pt) 2000-04-12 2001-04-10 Processo para preparação de 5'-acetilestavudina
JP2001575576A JP2003530394A (ja) 2000-04-12 2001-04-10 ５’−アセチルスタブジンの調製プロセス
DE60101791T DE60101791T2 (de) 2000-04-12 2001-04-10 Verfahren zur herstellung von 5'-acetylstavudin
KR1020027011340A KR100800650B1 (ko) 2000-04-12 2001-04-10 5'-아세틸스타부딘의 제조 방법
EP01917385A EP1274704B1 (en) 2000-04-12 2001-04-10 Process for preparing 5'-acetylstavudine
PCT/IB2001/000588 WO2001077103A1 (en) 2000-04-12 2001-04-10 Process for preparing 5'-acetylstavudine
MXPA02010072A MXPA02010072A (es) 2000-04-12 2001-04-10 Procedimiento para preparar 5'-acetilestavudina.
HU0300259A HUP0300259A3 (en) 2000-04-12 2001-04-10 Process for preparing 5'-acetylstavudine
AT01917385T ATE257835T1 (de) 2000-04-12 2001-04-10 Verfahren zur herstellung von 5'-acetylstavudin
US09/834,028 US6350873B2 (en) 2000-04-12 2001-04-12 Process for preparing 5′-acetylstavudine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000810A IT1318463B1 (it) 2000-04-12 2000-04-12 Procedimento per la preparazione di 5'-acetilstavudina.

Publications (3)

Publication Number Publication Date
ITMI20000810A0 ITMI20000810A0 (it) 2000-04-12
ITMI20000810A1 ITMI20000810A1 (it) 2001-10-12
IT1318463B1 true IT1318463B1 (it) 2003-08-25

Family

ID=11444838

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI000810A IT1318463B1 (it) 2000-04-12 2000-04-12 Procedimento per la preparazione di 5'-acetilstavudina.

Country Status (12)

Country Link
US (1) US6350873B2 (it)
EP (1) EP1274704B1 (it)
JP (1) JP2003530394A (it)
KR (1) KR100800650B1 (it)
AT (1) ATE257835T1 (it)
BR (1) BR0109965A (it)
DE (1) DE60101791T2 (it)
ES (1) ES2213109T3 (it)
HU (1) HUP0300259A3 (it)
IT (1) IT1318463B1 (it)
MX (1) MXPA02010072A (it)
WO (1) WO2001077103A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0617074A2 (pt) * 2005-08-31 2011-07-12 Cipla Ltd composição farmacêutica, uso de lamivudina, nevirapina e stavudina, uso de stavudina, lamivudina e nevirapina, método para tratar uma infecção viral em um humano, método para preparar uma composição farmacêutica, método para preparar uma forma de dosagem unitária farmacêutica bicamadas e método para preparar uma forma de dosagem unitária farmacêutica tri-camadas

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides

Also Published As

Publication number Publication date
ITMI20000810A0 (it) 2000-04-12
US6350873B2 (en) 2002-02-26
US20010039342A1 (en) 2001-11-08
ES2213109T3 (es) 2004-08-16
WO2001077103A1 (en) 2001-10-18
HUP0300259A2 (hu) 2003-06-28
DE60101791T2 (de) 2004-10-21
EP1274704B1 (en) 2004-01-14
JP2003530394A (ja) 2003-10-14
KR100800650B1 (ko) 2008-02-01
DE60101791D1 (de) 2004-02-19
HUP0300259A3 (en) 2005-12-28
ITMI20000810A1 (it) 2001-10-12
MXPA02010072A (es) 2003-03-10
BR0109965A (pt) 2003-05-27
KR20020086912A (ko) 2002-11-20
ATE257835T1 (de) 2004-01-15
EP1274704A1 (en) 2003-01-15

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