DE60101791D1 - Verfahren zur herstellung von 5'-acetylstavudin - Google Patents

Verfahren zur herstellung von 5'-acetylstavudin

Info

Publication number
DE60101791D1
DE60101791D1 DE60101791T DE60101791T DE60101791D1 DE 60101791 D1 DE60101791 D1 DE 60101791D1 DE 60101791 T DE60101791 T DE 60101791T DE 60101791 T DE60101791 T DE 60101791T DE 60101791 D1 DE60101791 D1 DE 60101791D1
Authority
DE
Germany
Prior art keywords
acetylstavudine
producing
didehydro
stavudine
deoxythymidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60101791T
Other languages
English (en)
Other versions
DE60101791T2 (de
Inventor
Giorgio Bertolini
Marco Frigerio
Maurizio Velati
Luigi Petrucciani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archimica SpA
Original Assignee
Clariant LSM Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant LSM Italia SpA filed Critical Clariant LSM Italia SpA
Publication of DE60101791D1 publication Critical patent/DE60101791D1/de
Application granted granted Critical
Publication of DE60101791T2 publication Critical patent/DE60101791T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60101791T 2000-04-12 2001-04-10 Verfahren zur herstellung von 5'-acetylstavudin Expired - Fee Related DE60101791T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000810A IT1318463B1 (it) 2000-04-12 2000-04-12 Procedimento per la preparazione di 5'-acetilstavudina.
PCT/IB2001/000588 WO2001077103A1 (en) 2000-04-12 2001-04-10 Process for preparing 5'-acetylstavudine

Publications (2)

Publication Number Publication Date
DE60101791D1 true DE60101791D1 (de) 2004-02-19
DE60101791T2 DE60101791T2 (de) 2004-10-21

Family

ID=11444838

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60101791T Expired - Fee Related DE60101791T2 (de) 2000-04-12 2001-04-10 Verfahren zur herstellung von 5'-acetylstavudin

Country Status (12)

Country Link
US (1) US6350873B2 (de)
EP (1) EP1274704B1 (de)
JP (1) JP2003530394A (de)
KR (1) KR100800650B1 (de)
AT (1) ATE257835T1 (de)
BR (1) BR0109965A (de)
DE (1) DE60101791T2 (de)
ES (1) ES2213109T3 (de)
HU (1) HUP0300259A3 (de)
IT (1) IT1318463B1 (de)
MX (1) MXPA02010072A (de)
WO (1) WO2001077103A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2008004389A0 (en) * 2005-08-31 2008-04-30 Cipla Ltd Pharmaceutical combinations containing lamivudine,stavudine,stavudine and navirapine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides

Also Published As

Publication number Publication date
MXPA02010072A (es) 2003-03-10
IT1318463B1 (it) 2003-08-25
US6350873B2 (en) 2002-02-26
ATE257835T1 (de) 2004-01-15
KR20020086912A (ko) 2002-11-20
EP1274704B1 (de) 2004-01-14
JP2003530394A (ja) 2003-10-14
US20010039342A1 (en) 2001-11-08
ITMI20000810A1 (it) 2001-10-12
ITMI20000810A0 (it) 2000-04-12
HUP0300259A2 (hu) 2003-06-28
DE60101791T2 (de) 2004-10-21
EP1274704A1 (de) 2003-01-15
ES2213109T3 (es) 2004-08-16
BR0109965A (pt) 2003-05-27
WO2001077103A1 (en) 2001-10-18
HUP0300259A3 (en) 2005-12-28
KR100800650B1 (ko) 2008-02-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ARCHIMICA S.R.L., MILANO, IT

8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8339 Ceased/non-payment of the annual fee