IT1226301B - Processo per la preparazione di intermedi per la sintesi del diltiazem. - Google Patents

Processo per la preparazione di intermedi per la sintesi del diltiazem.

Info

Publication number
IT1226301B
IT1226301B IT8821479A IT2147988A IT1226301B IT 1226301 B IT1226301 B IT 1226301B IT 8821479 A IT8821479 A IT 8821479A IT 2147988 A IT2147988 A IT 2147988A IT 1226301 B IT1226301 B IT 1226301B
Authority
IT
Italy
Prior art keywords
diltiazem
synthesis
intermediates
preparation
dimethylaminoethanol
Prior art date
Application number
IT8821479A
Other languages
English (en)
Other versions
IT8821479A0 (it
Inventor
Silvia Cavicchioli
Maurizio Paiocchi
Claudio Giordano
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT8821479A priority Critical patent/IT1226301B/it
Publication of IT8821479A0 publication Critical patent/IT8821479A0/it
Priority to AT89113136T priority patent/ATE103598T1/de
Priority to ES89113136T priority patent/ES2061819T3/es
Priority to DE68914211T priority patent/DE68914211T2/de
Priority to EP89113136A priority patent/EP0355395B1/en
Priority to US07/384,730 priority patent/US4937334A/en
Priority to JP01193818A priority patent/JP3101819B2/ja
Application granted granted Critical
Publication of IT1226301B publication Critical patent/IT1226301B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
IT8821479A 1988-07-26 1988-07-26 Processo per la preparazione di intermedi per la sintesi del diltiazem. IT1226301B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8821479A IT1226301B (it) 1988-07-26 1988-07-26 Processo per la preparazione di intermedi per la sintesi del diltiazem.
AT89113136T ATE103598T1 (de) 1988-07-26 1989-07-18 Verfahren zur herstellung von zwischenprodukten in der synthese von diltiazem.
ES89113136T ES2061819T3 (es) 1988-07-26 1989-07-18 Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem.
DE68914211T DE68914211T2 (de) 1988-07-26 1989-07-18 Verfahren zur Herstellung von Zwischenprodukten in der Synthese von Diltiazem.
EP89113136A EP0355395B1 (en) 1988-07-26 1989-07-18 Process for the preparation of intermediates for the synthesis of diltiazem
US07/384,730 US4937334A (en) 1988-07-26 1989-07-25 Process for the preparation of intermediates for the synthesis of diltiazem
JP01193818A JP3101819B2 (ja) 1988-07-26 1989-07-26 （２ｓ，３ｓ）（＋）―３―ヒドロキシ―２，３―ジヒドロ―２―（４―メトキシフェニル）―５―（２―ジメチルアミノエチル）―１，５―ベンゾチアゼピン―４（５ｈ）―オンの製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821479A IT1226301B (it) 1988-07-26 1988-07-26 Processo per la preparazione di intermedi per la sintesi del diltiazem.

Publications (2)

Publication Number Publication Date
IT8821479A0 IT8821479A0 (it) 1988-07-26
IT1226301B true IT1226301B (it) 1990-12-27

Family

ID=11182442

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8821479A IT1226301B (it) 1988-07-26 1988-07-26 Processo per la preparazione di intermedi per la sintesi del diltiazem.

Country Status (7)

Country Link
US (1) US4937334A (it)
EP (1) EP0355395B1 (it)
JP (1) JP3101819B2 (it)
AT (1) ATE103598T1 (it)
DE (1) DE68914211T2 (it)
ES (1) ES2061819T3 (it)
IT (1) IT1226301B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244878B (it) * 1990-12-11 1994-09-12 Lusochimica Spa Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato
TW438787B (en) 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester
FR3033701B1 (fr) 2015-03-19 2021-01-15 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
HU195795B (en) * 1985-11-06 1988-07-28 Richter Gedeon Vegyeszet Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Also Published As

Publication number Publication date
JPH0278673A (ja) 1990-03-19
EP0355395A1 (en) 1990-02-28
DE68914211T2 (de) 1994-07-07
JP3101819B2 (ja) 2000-10-23
ES2061819T3 (es) 1994-12-16
EP0355395B1 (en) 1994-03-30
DE68914211D1 (de) 1994-05-05
US4937334A (en) 1990-06-26
ATE103598T1 (de) 1994-04-15
IT8821479A0 (it) 1988-07-26

Similar Documents

Publication Publication Date Title
ES2088537T3 (es) Derivados de piranil cianoguanidina.
ATE112285T1 (de) Adenosin-derivate, die eine aktivität gegen bluthochdruck haben.
FI906045A0 (fi) Kvaevehaltiga spirocykliska foereningar.
CO4290427A1 (es) Preparacion de n-alquilcarboxilatos de piperidinilo 3,4,4- trisustituidos e intermedios
ES2188661T3 (es) Preparacion de un derivado de camptothecin por ciclacion intramolecular.
ITMI921203A1 (it) Derivati di s-triazina come agenti fotostabilizzanti
HUT52043A (en) Process for producing intermediates for producing substituted indolinon derivatives
DK0503453T3 (da) Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde
CA1273957C (it)
DE60333733D1 (en) Clohexancarbonsäurederivats
ITMI931012A1 (it) Composti spiro-piranici dotati di caratteristiche fotocromatiche
IT1226301B (it) Processo per la preparazione di intermedi per la sintesi del diltiazem.
FI955954A0 (fi) Thiolyhdisteitä
DE69915413D1 (de) Verfahren zur Herstellung von 4-phenyl-1,2,3,6-tetrahydropyridin-derivaten und die dafür verwendeten Zwischenprodukte
ES2053707T3 (es) Procedimiento para la preparacion de amidas de acidos 3,3-diaril-acrilicos.
BR9405302A (pt) Processo para a preparação de um composto e o referido composto
ES2061080T3 (es) Terpenos aciclicos.
IT1198237B (it) Intermedi per la sintesi di composti organici
ES2164258T3 (es) Procedimiento de preparacion de derivados de carbamoilmetilurea.
KR920021563A (ko) 니자티딘의 제조방법 및 그에 대한 중간체