ES2061819T3 - Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem. - Google Patents

Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem.

Info

Publication number
ES2061819T3
ES2061819T3 ES89113136T ES89113136T ES2061819T3 ES 2061819 T3 ES2061819 T3 ES 2061819T3 ES 89113136 T ES89113136 T ES 89113136T ES 89113136 T ES89113136 T ES 89113136T ES 2061819 T3 ES2061819 T3 ES 2061819T3
Authority
ES
Spain
Prior art keywords
synthesis
intermediaries
diltiazem
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89113136T
Other languages
English (en)
Inventor
Silvia Cavicchioli
Maurizio Paiocchi
Claudio Giordano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Application granted granted Critical
Publication of ES2061819T3 publication Critical patent/ES2061819T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Abstract

COMPUESTO DE FORMULA III, LA CUAL ES UN INTERMEDIO EN LA SINTESIS DE SOLUCIONES DE TIAZOL, SE PREPARA POR N-ALQUILACION DE LOS CORRESPONDIENTES DERIVADOS N-H CON 2-DIMETILAMINOETANOL EN UN DISOLVENTE INERTE Y EN PRESENCIA DE CLORURO DE METANOSULFONILO Y UNA BASE.
ES89113136T 1988-07-26 1989-07-18 Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem. Expired - Lifetime ES2061819T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821479A IT1226301B (it) 1988-07-26 1988-07-26 Processo per la preparazione di intermedi per la sintesi del diltiazem.

Publications (1)

Publication Number Publication Date
ES2061819T3 true ES2061819T3 (es) 1994-12-16

Family

ID=11182442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89113136T Expired - Lifetime ES2061819T3 (es) 1988-07-26 1989-07-18 Procedimiento para la preparacion de intermediarios para la sintesis de diltiazem.

Country Status (7)

Country Link
US (1) US4937334A (es)
EP (1) EP0355395B1 (es)
JP (1) JP3101819B2 (es)
AT (1) ATE103598T1 (es)
DE (1) DE68914211T2 (es)
ES (1) ES2061819T3 (es)
IT (1) IT1226301B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244878B (it) * 1990-12-11 1994-09-12 Lusochimica Spa Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato
TW438787B (en) 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester
FR3033701B1 (fr) 2015-03-19 2021-01-15 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
HU195795B (en) * 1985-11-06 1988-07-28 Richter Gedeon Vegyeszet Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Also Published As

Publication number Publication date
ATE103598T1 (de) 1994-04-15
US4937334A (en) 1990-06-26
JP3101819B2 (ja) 2000-10-23
DE68914211D1 (de) 1994-05-05
IT8821479A0 (it) 1988-07-26
EP0355395B1 (en) 1994-03-30
IT1226301B (it) 1990-12-27
DE68914211T2 (de) 1994-07-07
EP0355395A1 (en) 1990-02-28
JPH0278673A (ja) 1990-03-19

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