IN2014DN06869A - - Google Patents

Info

Publication number
IN2014DN06869A
IN2014DN06869A IN6869DEN2014A IN2014DN06869A IN 2014DN06869 A IN2014DN06869 A IN 2014DN06869A IN 6869DEN2014 A IN6869DEN2014 A IN 6869DEN2014A IN 2014DN06869 A IN2014DN06869 A IN 2014DN06869A
Authority
IN
India
Prior art keywords
subclasses
classes
pharmaceutically acceptable
treatment
pharmaceutical compositions
Prior art date
Application number
Other languages
English (en)
Inventor
Bijoy Panicker
Rama K Mishra
Dawoon Jung
Lambertus J W M Oehlen
Dong Sung Lim
Original Assignee
Angion Biomedica Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angion Biomedica Corp filed Critical Angion Biomedica Corp
Publication of IN2014DN06869A publication Critical patent/IN2014DN06869A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
IN6869DEN2014 2012-01-26 2013-01-26 IN2014DN06869A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261632582P 2012-01-26 2012-01-26
PCT/US2013/023324 WO2013112959A1 (fr) 2012-01-26 2013-01-26 Composés antifibrotiques et leurs utilisations

Publications (1)

Publication Number Publication Date
IN2014DN06869A true IN2014DN06869A (fr) 2015-05-22

Family

ID=48873985

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6869DEN2014 IN2014DN06869A (fr) 2012-01-26 2013-01-26

Country Status (15)

Country Link
US (4) US9040555B2 (fr)
EP (2) EP3604307A1 (fr)
JP (1) JP6152389B2 (fr)
CN (1) CN104136436B (fr)
AU (1) AU2013211888B2 (fr)
CA (1) CA2862692C (fr)
DK (1) DK2807160T3 (fr)
ES (1) ES2748873T3 (fr)
HK (1) HK1203502A1 (fr)
HU (1) HUE046368T2 (fr)
IL (2) IL233727A (fr)
IN (1) IN2014DN06869A (fr)
PL (1) PL2807160T3 (fr)
PT (1) PT2807160T (fr)
WO (1) WO2013112959A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104136436B (zh) 2012-01-26 2019-01-01 安贞生物医学公司 抗纤维化的化合物及其用途
US9597321B2 (en) * 2012-01-26 2017-03-21 Angion Biomedica Corp. Antifibrotic compounds and uses thereof
US20150105380A1 (en) * 2013-09-23 2015-04-16 Angion Biomedica Corp. Methods and uses of compounds for treating disease
CN104387385B (zh) * 2014-11-14 2016-03-23 苏州和健医药科技有限公司 6-羧酸甲酯-2-氧-7-氮杂吲哚及其制备方法与应用
CN108368108B (zh) * 2015-11-12 2021-09-21 岭南大学研究合作基金会 包含作为活性成分的7-氮杂吲哚啉-2-酮衍生物或其可药用盐的药物组合物
EA038773B1 (ru) 2016-03-08 2021-10-18 Респиверт Лимитед Индольные производные и их применение в качестве ингибиторов протеинкиназы
AU2017277524B2 (en) * 2016-06-07 2021-07-29 Dermavant Sciences GmbH Topical formulations of PDE-4 inhibitors and their methods of use
IL293013A (en) * 2019-11-20 2022-07-01 Angion Biomedica Corp Methods for treating inflammatory bowel disease
WO2022006278A1 (fr) * 2020-07-01 2022-01-06 Angion Biomedica Corp. Réduction de la fibrose et traitement de maladies, de troubles et d'états associés
WO2022006277A1 (fr) * 2020-07-01 2022-01-06 Angion Biomedica Corp. Méthodes de traitement de maladies rénales fibrotiques
US20230312561A1 (en) * 2020-07-01 2023-10-05 Angion Biomedica Corp. Solid forms of (z)-methyl 3-(((4-(n-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine-6-carboxylate and salts thereof
WO2022165092A1 (fr) * 2021-01-29 2022-08-04 Angion Biomedica Corp. Méthodes de traitement de maladies fibrotiques

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
GB9721437D0 (en) * 1997-10-10 1997-12-10 Glaxo Group Ltd Heteroaromatic compounds and their use in medicine
WO1999065875A1 (fr) 1998-06-17 1999-12-23 Geron Corporation Inhibiteurs de la telomerase
GB9904995D0 (en) * 1999-03-04 1999-04-28 Glaxo Group Ltd Substituted aza-oxindole derivatives
US6982265B1 (en) 1999-05-21 2006-01-03 Bristol Myers Squibb Company Pyrrolotriazine inhibitors of kinases
US6762180B1 (en) * 1999-10-13 2004-07-13 Boehringer Ingelheim Pharma Kg Substituted indolines which inhibit receptor tyrosine kinases
UA75054C2 (uk) 1999-10-13 2006-03-15 Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу
CA2407799A1 (fr) * 2000-05-02 2001-11-08 Sugen, Inc. Derives d'acide acetique (2-oxindole-3-ylidenyl) et leur utilisation comme inhibiteurs de la proteine kinase
JP2006510727A (ja) * 2002-11-15 2006-03-30 エクセリクシス, インク. キナーゼモジュレーター
PE20060777A1 (es) * 2004-12-24 2006-10-06 Boehringer Ingelheim Int Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
WO2008138232A1 (fr) 2007-05-14 2008-11-20 Shanghai Hengrui Pharmaceutical Co., Ltd. Dérivés pyrrolo-azotés hétérocycliques, leur préparation et leur utilisation pharmaceutique
WO2008138184A1 (fr) 2007-05-14 2008-11-20 Shanghai Hengrui Pharmaceutical Co.Ltd. Dérivés de pyrrolo-azacycles, leur procédé de fabrication et leur utilisation en tant qu'inhibiteurs de protéine kinases
WO2009042646A1 (fr) 2007-09-24 2009-04-02 Curis, Inc. Agents antiprolifératifs
TWI440638B (zh) * 2007-10-30 2014-06-11 Otsuka Pharma Co Ltd 雜環化合物及其藥學組成物
WO2010088000A2 (fr) * 2009-02-02 2010-08-05 Angion Biomedica Corp. Composés antifibrotiques et leurs utilisations
WO2010144959A1 (fr) * 2009-06-18 2010-12-23 Fibrotech Therapeutics Pty Ltd Analogues d'agents antifibrotiques
JP2011213697A (ja) * 2010-04-02 2011-10-27 Astellas Pharma Inc アントラサイクリン化合物
CN104136436B (zh) * 2012-01-26 2019-01-01 安贞生物医学公司 抗纤维化的化合物及其用途
US9597321B2 (en) * 2012-01-26 2017-03-21 Angion Biomedica Corp. Antifibrotic compounds and uses thereof
US20150105380A1 (en) 2013-09-23 2015-04-16 Angion Biomedica Corp. Methods and uses of compounds for treating disease

Also Published As

Publication number Publication date
IL251974B (en) 2020-08-31
AU2013211888B2 (en) 2017-08-31
EP2807160A1 (fr) 2014-12-03
EP3604307A1 (fr) 2020-02-05
ES2748873T3 (es) 2020-03-18
EP2807160A4 (fr) 2014-12-24
AU2013211888A1 (en) 2014-08-14
JP6152389B2 (ja) 2017-06-21
US11504359B2 (en) 2022-11-22
CA2862692C (fr) 2021-05-04
US9040555B2 (en) 2015-05-26
HUE046368T2 (hu) 2020-02-28
CN104136436A (zh) 2014-11-05
JP2015505543A (ja) 2015-02-23
CN104136436B (zh) 2019-01-01
US20180008581A1 (en) 2018-01-11
EP2807160B1 (fr) 2019-07-24
DK2807160T3 (da) 2019-10-14
WO2013112959A1 (fr) 2013-08-01
US20200069662A1 (en) 2020-03-05
US20140371234A1 (en) 2014-12-18
US20190125731A1 (en) 2019-05-02
IL251974A0 (en) 2017-06-29
PT2807160T (pt) 2019-10-28
US10195184B2 (en) 2019-02-05
PL2807160T3 (pl) 2020-03-31
HK1203502A1 (en) 2015-10-30
CA2862692A1 (fr) 2013-08-01
WO2013112959A8 (fr) 2013-09-12
WO2013112959A9 (fr) 2015-01-15
IL233727A (en) 2017-05-29

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