IL96812A - 3-Hydroxy-2-hydroxymethyl (-Propionamide-2,4,6-triiodoisopthalamide nonionic, their preparation and contrast media containing them - Google Patents
3-Hydroxy-2-hydroxymethyl (-Propionamide-2,4,6-triiodoisopthalamide nonionic, their preparation and contrast media containing themInfo
- Publication number
- IL96812A IL96812A IL9681290A IL9681290A IL96812A IL 96812 A IL96812 A IL 96812A IL 9681290 A IL9681290 A IL 9681290A IL 9681290 A IL9681290 A IL 9681290A IL 96812 A IL96812 A IL 96812A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- ppm
- hydroxy
- contrast media
- hydroxymethyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9000106A FR2656865B1 (fr) | 1990-01-05 | 1990-01-05 | Compose non ionique iode, son procede de preparation et produit de contraste le contenant. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL96812A0 IL96812A0 (en) | 1991-09-16 |
IL96812A true IL96812A (en) | 1995-05-26 |
Family
ID=9392557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9681290A IL96812A (en) | 1990-01-05 | 1990-12-27 | 3-Hydroxy-2-hydroxymethyl (-Propionamide-2,4,6-triiodoisopthalamide nonionic, their preparation and contrast media containing them |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0437144B1 (ja) |
JP (1) | JP2529032B2 (ja) |
KR (1) | KR100194506B1 (ja) |
AT (1) | ATE114639T1 (ja) |
CA (1) | CA2050334C (ja) |
CZ (1) | CZ283986B6 (ja) |
DE (1) | DE69014581T2 (ja) |
DK (1) | DK0437144T3 (ja) |
ES (1) | ES2067710T3 (ja) |
FI (1) | FI102746B (ja) |
FR (1) | FR2656865B1 (ja) |
GR (1) | GR3015183T3 (ja) |
HK (1) | HK1006019A1 (ja) |
HU (1) | HUT59079A (ja) |
IE (1) | IE65329B1 (ja) |
IL (1) | IL96812A (ja) |
NO (1) | NO180297C (ja) |
NZ (1) | NZ236675A (ja) |
PL (1) | PL165683B1 (ja) |
PT (1) | PT96410B (ja) |
RO (1) | RO108559B1 (ja) |
SK (1) | SK279646B6 (ja) |
TR (1) | TR24944A (ja) |
WO (1) | WO1991009836A1 (ja) |
ZA (1) | ZA9173B (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2687669B1 (fr) * | 1992-02-24 | 1997-12-19 | Guerbet Sa | Composes utilisables dans des produits de contraste pour la radiographie. |
IT1256163B (it) * | 1992-10-27 | 1995-11-29 | Zambon Spa | Processo per la preparazione di un intermedio della sintesi organica |
IT1283319B1 (it) * | 1996-03-29 | 1998-04-16 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati |
PT108524B (pt) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
CN108947959B (zh) * | 2017-05-27 | 2022-09-20 | 正大天晴药业集团股份有限公司 | 一种非离子型碘造影剂中间体的制备方法 |
CN110903275A (zh) * | 2018-09-14 | 2020-03-24 | 苏州科伦药物研究有限公司 | 制备碘比醇的方法、其中间体及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
DE3429949A1 (de) * | 1984-08-10 | 1986-02-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel |
IL90326A (en) * | 1988-06-02 | 1993-05-13 | Guerbet Sa | Non-ionic triiodobenzene compounds and contrast media containing them |
-
1990
- 1990-01-05 FR FR9000106A patent/FR2656865B1/fr not_active Expired - Fee Related
- 1990-12-20 SK SK6482-90A patent/SK279646B6/sk unknown
- 1990-12-20 CZ CS906482A patent/CZ283986B6/cs not_active IP Right Cessation
- 1990-12-26 EP EP90403770A patent/EP0437144B1/fr not_active Expired - Lifetime
- 1990-12-26 AT AT90403770T patent/ATE114639T1/de not_active IP Right Cessation
- 1990-12-26 DK DK90403770.2T patent/DK0437144T3/da active
- 1990-12-26 ES ES90403770T patent/ES2067710T3/es not_active Expired - Lifetime
- 1990-12-26 DE DE69014581T patent/DE69014581T2/de not_active Expired - Lifetime
- 1990-12-27 IL IL9681290A patent/IL96812A/en not_active IP Right Cessation
- 1990-12-28 CA CA002050334A patent/CA2050334C/en not_active Expired - Lifetime
- 1990-12-28 WO PCT/FR1990/000969 patent/WO1991009836A1/fr active IP Right Grant
- 1990-12-28 HU HU912860A patent/HUT59079A/hu unknown
- 1990-12-28 KR KR1019910701024A patent/KR100194506B1/ko not_active IP Right Cessation
- 1990-12-28 RO RO148263A patent/RO108559B1/ro unknown
-
1991
- 1991-01-03 PT PT96410A patent/PT96410B/pt not_active IP Right Cessation
- 1991-01-04 JP JP3052354A patent/JP2529032B2/ja not_active Expired - Lifetime
- 1991-01-04 ZA ZA9173A patent/ZA9173B/xx unknown
- 1991-01-04 IE IE3591A patent/IE65329B1/en not_active IP Right Cessation
- 1991-01-04 PL PL91288603A patent/PL165683B1/pl not_active IP Right Cessation
- 1991-01-04 NZ NZ236675A patent/NZ236675A/en unknown
- 1991-01-18 TR TR91/0009A patent/TR24944A/xx unknown
- 1991-08-30 NO NO913403A patent/NO180297C/no not_active IP Right Cessation
- 1991-09-02 FI FI914114A patent/FI102746B/fi active
-
1995
- 1995-02-27 GR GR940403887T patent/GR3015183T3/el unknown
-
1998
- 1998-06-10 HK HK98105100A patent/HK1006019A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |