IL95121A - דיאמידים של חומצה (n, n-ביס )אלקאוקסיאלקיל(פירידין-2,4- דיקרבוקסילית, תהליך להכנתם ותכשירי רוקחות המכיליםאותם - Google Patents

דיאמידים של חומצה (n, n-ביס )אלקאוקסיאלקיל(פירידין-2,4- דיקרבוקסילית, תהליך להכנתם ותכשירי רוקחות המכיליםאותם

Info

Publication number
IL95121A
IL95121A IL9512190A IL9512190A IL95121A IL 95121 A IL95121 A IL 95121A IL 9512190 A IL9512190 A IL 9512190A IL 9512190 A IL9512190 A IL 9512190A IL 95121 A IL95121 A IL 95121A
Authority
IL
Israel
Prior art keywords
pyridine
formula
compound
bis
dicarboxylic acid
Prior art date
Application number
IL9512190A
Other languages
English (en)
Other versions
IL95121A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL95121A0 publication Critical patent/IL95121A0/xx
Publication of IL95121A publication Critical patent/IL95121A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL9512190A 1989-07-20 1990-07-18 דיאמידים של חומצה (n, n-ביס )אלקאוקסיאלקיל(פירידין-2,4- דיקרבוקסילית, תהליך להכנתם ותכשירי רוקחות המכיליםאותם IL95121A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3924093A DE3924093A1 (de) 1989-07-20 1989-07-20 N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung

Publications (2)

Publication Number Publication Date
IL95121A0 IL95121A0 (en) 1991-06-10
IL95121A true IL95121A (he) 1994-08-26

Family

ID=6385494

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9512190A IL95121A (he) 1989-07-20 1990-07-18 דיאמידים של חומצה (n, n-ביס )אלקאוקסיאלקיל(פירידין-2,4- דיקרבוקסילית, תהליך להכנתם ותכשירי רוקחות המכיליםאותם

Country Status (26)

Country Link
EP (1) EP0409119B1 (he)
JP (1) JPH0776213B2 (he)
KR (1) KR0181945B1 (he)
AT (1) ATE104280T1 (he)
AU (1) AU624978B2 (he)
CA (1) CA2021529C (he)
CY (1) CY1997A (he)
CZ (1) CZ280129B6 (he)
DD (1) DD300429A5 (he)
DE (2) DE3924093A1 (he)
DK (1) DK0409119T3 (he)
ES (1) ES2052112T3 (he)
FI (1) FI94630C (he)
HU (1) HU218274B (he)
IE (1) IE64438B1 (he)
IL (1) IL95121A (he)
LT (1) LT3798B (he)
LV (1) LV10430B (he)
NO (1) NO177187C (he)
NZ (1) NZ234563A (he)
PL (1) PL166307B1 (he)
PT (1) PT94779B (he)
RU (1) RU1836350C (he)
SK (1) SK279199B6 (he)
UA (1) UA19056A (he)
ZA (1) ZA905680B (he)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
TW199147B (he) * 1991-03-18 1993-02-01 Hoechst Ag
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW222585B (he) * 1992-09-11 1994-04-21 Hoechst Ag
DOP2002000332A (es) * 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3703963A1 (de) 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3828140A1 (de) 1988-08-19 1990-03-01 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden sowie verwendung dieser verbindungen zur herstellung oralverabreichbarer arzneimittel
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE3826471A1 (de) 1988-08-04 1990-02-22 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden

Also Published As

Publication number Publication date
LT3798B (en) 1996-03-25
LV10430B (en) 1996-02-20
PT94779A (pt) 1991-03-20
NO177187C (no) 1995-08-02
EP0409119A1 (de) 1991-01-23
PL286132A1 (en) 1991-07-29
FI903624A0 (fi) 1990-07-18
IE64438B1 (en) 1995-08-09
DE3924093A1 (de) 1991-02-07
HU218274B (en) 2000-07-28
IL95121A0 (en) 1991-06-10
CZ357690A3 (en) 1995-06-14
FI94630C (fi) 1995-10-10
PT94779B (pt) 1997-04-30
UA19056A (uk) 1997-12-25
LTIP1462A (en) 1995-05-25
CY1997A (en) 1997-09-05
DK0409119T3 (da) 1994-08-08
NO903235L (no) 1991-01-21
JPH0776213B2 (ja) 1995-08-16
NZ234563A (en) 1992-12-23
FI94630B (fi) 1995-06-30
NO903235D0 (no) 1990-07-19
HUT54653A (en) 1991-03-28
CZ280129B6 (cs) 1995-11-15
LV10430A (lv) 1995-02-20
ZA905680B (en) 1991-04-24
EP0409119B1 (de) 1994-04-13
KR910002799A (ko) 1991-02-26
SK357690A3 (en) 1998-07-08
HU904549D0 (en) 1990-12-28
AU5914490A (en) 1991-01-24
ES2052112T3 (es) 1994-07-01
DE59005328D1 (de) 1994-05-19
AU624978B2 (en) 1992-06-25
KR0181945B1 (ko) 1999-05-01
JPH0358973A (ja) 1991-03-14
RU1836350C (ru) 1993-08-23
DD300429A5 (de) 1992-06-11
CA2021529A1 (en) 1991-01-21
PL166307B1 (pl) 1995-05-31
CA2021529C (en) 1997-12-30
ATE104280T1 (de) 1994-04-15
NO177187B (no) 1995-04-24
SK279199B6 (sk) 1998-07-08
IE902642A1 (en) 1991-02-27

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