FI94630B - Analogiamenetelmä terapeuttisesti käyttökelpoisten N,N'-bis(alkoksi- ja hydroksialkyyli)pyridiini-2,4-dikarboksyylihappodiamidien valmistamiseksi - Google Patents

Analogiamenetelmä terapeuttisesti käyttökelpoisten N,N'-bis(alkoksi- ja hydroksialkyyli)pyridiini-2,4-dikarboksyylihappodiamidien valmistamiseksi

Info

Publication number
FI94630B
FI94630B FI903624A FI903624A FI94630B FI 94630 B FI94630 B FI 94630B FI 903624 A FI903624 A FI 903624A FI 903624 A FI903624 A FI 903624A FI 94630 B FI94630 B FI 94630B
Authority
FI
Finland
Prior art keywords
pyridine
bis
dicarboxylic acid
hydroxyalkyl
alkoxy
Prior art date
Application number
FI903624A
Other languages
English (en)
Swedish (sv)
Other versions
FI903624A0 (fi
FI94630C (fi
Inventor
Ekkehard Baader
Martin Bickel
Volkmar Guenzler-Pukall
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI903624A0 publication Critical patent/FI903624A0/fi
Application granted granted Critical
Publication of FI94630B publication Critical patent/FI94630B/fi
Publication of FI94630C publication Critical patent/FI94630C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI903624A 1989-07-20 1990-07-18 Analogiamenetelmä terapeuttisesti käyttökelpoisten N,N'-bis(alkoksi- ja hydroksialkyyli)pyridiini-2,4-dikarboksyylihappodiamidien valmistamiseksi FI94630C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3924093A DE3924093A1 (de) 1989-07-20 1989-07-20 N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3924093 1989-07-20

Publications (3)

Publication Number Publication Date
FI903624A0 FI903624A0 (fi) 1990-07-18
FI94630B true FI94630B (fi) 1995-06-30
FI94630C FI94630C (fi) 1995-10-10

Family

ID=6385494

Family Applications (1)

Application Number Title Priority Date Filing Date
FI903624A FI94630C (fi) 1989-07-20 1990-07-18 Analogiamenetelmä terapeuttisesti käyttökelpoisten N,N'-bis(alkoksi- ja hydroksialkyyli)pyridiini-2,4-dikarboksyylihappodiamidien valmistamiseksi

Country Status (26)

Country Link
EP (1) EP0409119B1 (fi)
JP (1) JPH0776213B2 (fi)
KR (1) KR0181945B1 (fi)
AT (1) ATE104280T1 (fi)
AU (1) AU624978B2 (fi)
CA (1) CA2021529C (fi)
CY (1) CY1997A (fi)
CZ (1) CZ280129B6 (fi)
DD (1) DD300429A5 (fi)
DE (2) DE3924093A1 (fi)
DK (1) DK0409119T3 (fi)
ES (1) ES2052112T3 (fi)
FI (1) FI94630C (fi)
HU (1) HU218274B (fi)
IE (1) IE64438B1 (fi)
IL (1) IL95121A (fi)
LT (1) LT3798B (fi)
LV (1) LV10430B (fi)
NO (1) NO177187C (fi)
NZ (1) NZ234563A (fi)
PL (1) PL166307B1 (fi)
PT (1) PT94779B (fi)
RU (1) RU1836350C (fi)
SK (1) SK279199B6 (fi)
UA (1) UA19056A (fi)
ZA (1) ZA905680B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
TW199147B (fi) * 1991-03-18 1993-02-01 Hoechst Ag
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW222585B (fi) * 1992-09-11 1994-04-21 Hoechst Ag
DOP2002000332A (es) * 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3703963A1 (de) 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3828140A1 (de) 1988-08-19 1990-03-01 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden sowie verwendung dieser verbindungen zur herstellung oralverabreichbarer arzneimittel
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE3826471A1 (de) 1988-08-04 1990-02-22 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden

Also Published As

Publication number Publication date
LT3798B (en) 1996-03-25
LV10430B (en) 1996-02-20
IL95121A (en) 1994-08-26
PT94779A (pt) 1991-03-20
NO177187C (no) 1995-08-02
EP0409119A1 (de) 1991-01-23
PL286132A1 (en) 1991-07-29
FI903624A0 (fi) 1990-07-18
IE64438B1 (en) 1995-08-09
DE3924093A1 (de) 1991-02-07
HU218274B (en) 2000-07-28
IL95121A0 (en) 1991-06-10
CZ357690A3 (en) 1995-06-14
FI94630C (fi) 1995-10-10
PT94779B (pt) 1997-04-30
UA19056A (uk) 1997-12-25
LTIP1462A (en) 1995-05-25
CY1997A (en) 1997-09-05
DK0409119T3 (da) 1994-08-08
NO903235L (no) 1991-01-21
JPH0776213B2 (ja) 1995-08-16
NZ234563A (en) 1992-12-23
NO903235D0 (no) 1990-07-19
HUT54653A (en) 1991-03-28
CZ280129B6 (cs) 1995-11-15
LV10430A (lv) 1995-02-20
ZA905680B (en) 1991-04-24
EP0409119B1 (de) 1994-04-13
KR910002799A (ko) 1991-02-26
SK357690A3 (en) 1998-07-08
HU904549D0 (en) 1990-12-28
AU5914490A (en) 1991-01-24
ES2052112T3 (es) 1994-07-01
DE59005328D1 (de) 1994-05-19
AU624978B2 (en) 1992-06-25
KR0181945B1 (ko) 1999-05-01
JPH0358973A (ja) 1991-03-14
RU1836350C (ru) 1993-08-23
DD300429A5 (de) 1992-06-11
CA2021529A1 (en) 1991-01-21
PL166307B1 (pl) 1995-05-31
CA2021529C (en) 1997-12-30
ATE104280T1 (de) 1994-04-15
NO177187B (no) 1995-04-24
SK279199B6 (sk) 1998-07-08
IE902642A1 (en) 1991-02-27

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MM Patent lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT