IL62602A - Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL62602A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; pyridoxine derivatives; pyridoxine
Prior art date: 1980-05-19

Application number

IL62602A

Other languages

English (en)

Other versions

IL62602A0 (en

Inventor

Marcel Descamps

Marcel Urbain

Original Assignee

Labaz Sanofi Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-19

Filing date

1981-04-07

Publication date

1984-06-29

1981-04-07 Application filed by Labaz Sanofi Nv filed Critical Labaz Sanofi Nv

1981-06-29 Publication of IL62602A0 publication Critical patent/IL62602A0/xx

1984-06-29 Publication of IL62602A publication Critical patent/IL62602A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

IL62602A 1980-05-19 1981-04-07 Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them IL62602A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8016516		1980-05-19

Publications (2)

Publication Number	Publication Date
IL62602A0 IL62602A0 (en)	1981-06-29
IL62602A true IL62602A (en)	1984-06-29

Family

ID=10513518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL62602A IL62602A (en)	1980-05-19	1981-04-07	Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (32)

Country	Link
US (1)	US4374841A (es)
EP (1)	EP0040591B1 (es)
JP (1)	JPS5711966A (es)
AR (1)	AR226356A1 (es)
AT (1)	ATE3859T1 (es)
AU (1)	AU542463B2 (es)
BG (1)	BG35327A3 (es)
CA (1)	CA1152080A (es)
CS (1)	CS223842B2 (es)
DD (1)	DD159071A5 (es)
DE (1)	DE3160480D1 (es)
DK (1)	DK217481A (es)
EG (1)	EG15890A (es)
ES (1)	ES502276A0 (es)
FI (1)	FI811525L (es)
GR (1)	GR82343B (es)
HU (1)	HU183441B (es)
IE (1)	IE51179B1 (es)
IL (1)	IL62602A (es)
IN (1)	IN151915B (es)
IS (1)	IS1183B6 (es)
MA (1)	MA19147A1 (es)
NO (1)	NO811680L (es)
NZ (1)	NZ196766A (es)
OA (1)	OA06811A (es)
PL (1)	PL129213B1 (es)
PT (1)	PT72992B (es)
RO (1)	RO81943A (es)
SU (1)	SU1077566A3 (es)
YU (1)	YU126281A (es)
ZA (1)	ZA812448B (es)
ZW (1)	ZW9681A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4663354A (en) *	1984-04-26	1987-05-05	Klinge Pharma Gmbh	Use of etilefrin and etilefrin pivalate in the long term treatment of circulatory disorders not due to hypotonia
DE3519693A1 (de) *	1985-06-01	1987-01-02	Basf Ag	Pyridin-derivate, ihre herstellung und verwendung
US6051587A (en) *	1998-04-16	2000-04-18	Medicure, Inc.	Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein
US6043259A (en) *	1998-07-09	2000-03-28	Medicure Inc.	Treatment of cardiovascular and related pathologies
US6339085B1 (en)	1999-03-08	2002-01-15	The University Of Manitoba	Therapeutics for cardiovascular and related diseases
US6489345B1 (en)	1999-07-13	2002-12-03	Medicure, Inc.	Treatment of diabetes and related pathologies
EP1872797A3 (en) *	1999-08-24	2008-04-02	Medicure International Inc.	Treatment of cardiovascular and related pathologies
US7442689B2 (en) *	2000-02-29	2008-10-28	Medicure International Inc.	Cardioprotective phosphonates and malonates
JP2003525303A (ja)	2000-02-29	2003-08-26	メディキュアインターナショナルインコーポレイテッド	心臓保護ホスホン酸塩およびマロン酸塩
EP1278526A2 (en)	2000-03-28	2003-01-29	Medicure International Inc.	Treatment of cerebrovascular disease
ATE364595T1 (de)	2000-07-07	2007-07-15	Medicure Int Inc	Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika
US6548519B1 (en)	2001-07-06	2003-04-15	Medicure International Inc.	Pyridoxine and pyridoxal analogues: novel uses
US6897228B2 (en) *	2000-07-07	2005-05-24	Medicure International Inc.	Pyridoxine and pyridoxal analogues: new uses
US20040121988A1 (en) *	2001-03-28	2004-06-24	Medicure International Inc.	Treatment of cerebrovascular disease
JP4048166B2 (ja) *	2002-11-18	2008-02-13	三井製糖株式会社	血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料
US20040186077A1 (en) *	2003-03-17	2004-09-23	Medicure International Inc.	Novel heteroaryl phosphonates as cardioprotective agents
AU2004224566A1 (en) *	2003-03-27	2004-10-07	Medicure Inc.	Compositions for treating angina
EP1773370A1 (en) *	2004-07-07	2007-04-18	Medicure International Inc.	Combination therapies employing platelet aggregation drugs
US20070060549A1 (en) *	2004-08-10	2007-03-15	Friesen Albert D	Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
WO2006050598A1 (en) *	2004-10-28	2006-05-18	Medicure International Inc.	Dual antiplatelet/anticoagulant pyridoxine analogs
US20060094749A1 (en) *	2004-10-28	2006-05-04	Medicure International Inc.	Substituted pyridoxines as anti-platelet agents
US7459468B2 (en) *	2004-10-28	2008-12-02	Medicure International, Inc.	Aryl sulfonic pyridoxines as antiplatelet agents
WO2007059631A1 (en) *	2005-11-28	2007-05-31	Medicure International Inc.	Selected dosage for the treatment of cardiovascular and related pathologies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4115575A (en) *	1973-02-20	1978-09-19	Ciba-Geigy Corporation	2-(3-Amino-2-hydroxy-propoxy)-pyrazines
AR207133A1 (es) *	1973-02-20	1976-09-15	Ciba Geigy Ag	Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
GB1485919A (en) *	1975-08-12	1977-09-14	Grindstedvaerket As	Pyridine derivatives
DE2711655A1 (de) *	1977-03-17	1978-09-21	Basf Ag	Pyridinyl-aminoalkylaether
US4210653A (en) *	1978-06-27	1980-07-01	Merck & Co., Inc.	Pyridyloxypropanolamines

1981
- 1981-04-07 IL IL62602A patent/IL62602A/xx unknown
- 1981-04-08 NZ NZ196766A patent/NZ196766A/en unknown
- 1981-04-10 IS IS2631A patent/IS1183B6/is unknown
- 1981-04-13 ZA ZA00812448A patent/ZA812448B/xx unknown
- 1981-04-14 GR GR64686A patent/GR82343B/el unknown
- 1981-04-27 ZW ZW96/81A patent/ZW9681A1/xx unknown
- 1981-04-28 BG BG8151875A patent/BG35327A3/xx unknown
- 1981-05-02 IN IN465/CAL/81A patent/IN151915B/en unknown
- 1981-05-07 PT PT72992A patent/PT72992B/pt unknown
- 1981-05-07 AR AR285225A patent/AR226356A1/es active
- 1981-05-11 US US06/262,449 patent/US4374841A/en not_active Expired - Fee Related
- 1981-05-12 EG EG260/81A patent/EG15890A/xx active
- 1981-05-13 MA MA19356A patent/MA19147A1/fr unknown
- 1981-05-13 AU AU70535/81A patent/AU542463B2/en not_active Ceased
- 1981-05-15 AT AT81870023T patent/ATE3859T1/de not_active IP Right Cessation
- 1981-05-15 DE DE8181870023T patent/DE3160480D1/de not_active Expired
- 1981-05-15 EP EP81870023A patent/EP0040591B1/fr not_active Expired
- 1981-05-15 CA CA000377739A patent/CA1152080A/en not_active Expired
- 1981-05-15 IE IE1085/81A patent/IE51179B1/en unknown
- 1981-05-15 YU YU01262/81A patent/YU126281A/xx unknown
- 1981-05-15 JP JP7407681A patent/JPS5711966A/ja active Pending
- 1981-05-15 PL PL1981231193A patent/PL129213B1/pl unknown
- 1981-05-15 CS CS813634A patent/CS223842B2/cs unknown
- 1981-05-18 SU SU813289800A patent/SU1077566A3/ru active
- 1981-05-18 DD DD81230039A patent/DD159071A5/de unknown
- 1981-05-18 HU HU811402A patent/HU183441B/hu unknown
- 1981-05-18 ES ES502276A patent/ES502276A0/es active Granted
- 1981-05-18 DK DK217481A patent/DK217481A/da not_active Application Discontinuation
- 1981-05-18 RO RO81104319A patent/RO81943A/ro unknown
- 1981-05-18 FI FI811525A patent/FI811525L/fi not_active Application Discontinuation
- 1981-05-18 OA OA57404A patent/OA06811A/xx unknown
- 1981-05-18 NO NO811680A patent/NO811680L/no unknown

Also Published As

Publication number	Publication date
PT72992A (en)	1981-06-01
NO811680L (no)	1981-11-20
DE3160480D1 (en)	1983-07-28
AR226356A1 (es)	1982-06-30
OA06811A (fr)	1982-12-31
IE811085L (en)	1981-11-19
DD159071A5 (de)	1983-02-16
NZ196766A (en)	1984-02-03
SU1077566A3 (ru)	1984-02-29
ATE3859T1 (de)	1983-07-15
AU542463B2 (en)	1985-02-21
ZA812448B (en)	1982-04-28
YU126281A (en)	1984-02-29
IL62602A0 (en)	1981-06-29
HU183441B (en)	1984-05-28
AU7053581A (en)	1981-11-26
PL129213B1 (en)	1984-04-30
RO81943B (ro)	1983-05-30
FI811525L (fi)	1981-11-20
PT72992B (en)	1982-07-01
IN151915B (es)	1983-09-03
MA19147A1 (fr)	1981-12-31
RO81943A (ro)	1983-06-01
DK217481A (da)	1981-11-20
IE51179B1 (en)	1986-10-29
ES8203845A1 (es)	1982-04-01
CA1152080A (en)	1983-08-16
US4374841A (en)	1983-02-22
CS223842B2 (en)	1983-11-25
ZW9681A1 (en)	1982-01-20
JPS5711966A (en)	1982-01-21
ES502276A0 (es)	1982-04-01
PL231193A1 (es)	1982-07-05
GR82343B (es)	1984-12-13
EP0040591A1 (fr)	1981-11-25
BG35327A3 (en)	1984-03-15
IS1183B6 (is)	1985-05-13
IS2631A7 (is)	1981-11-11
EP0040591B1 (fr)	1983-06-22
EG15890A (en)	1987-03-30

Publication	Publication Date	Title
IL65257A0 (en)	1983-12-30	Arylcyclo-butanealkylamine derivatives,their preparation and pharmaceutical compositions containing them
IL62200A (en)	1984-09-30	Piperidine derivatives,their preparation and pharmaceutical compositions containing them
IL62694A0 (en)	1981-06-29	Aminothiadiazole derivatives,their preparation and pharmaceutical compositions containing them
IL65803A (en)	1988-02-29	Cyclobutene-dione derivatives,their preparation and pharmaceutical compositions containing them
IL62602A (en)	1984-06-29	Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
IL63428A (en)	1984-12-31	2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL64777A0 (en)	1982-03-31	3-aminopropoxyaryl derivatives,their preparation and pharmaceutical compositions containing them
ZA816826B (en)	1983-06-29	Pyridine derivatives, processes for their preparation, and pharmaceutical compositions thereof
IL65327A0 (en)	1982-05-31	Acylquinolinone derivatives,their preparation and pharmaceutical compositions containing them
IL62824A (en)	1984-07-31	Phthalyltaurine derivatives,their preparation and pharmaceutical compositions comprising them
IL65422A0 (en)	1982-07-30	2-piperazino-pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
DE3169095D1 (en)	1985-03-28	3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL62229A0 (en)	1981-03-31	Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
IL63965A0 (en)	1981-12-31	Cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL62295A0 (en)	1981-05-20	Pyrazolopyridine derivatives,their preparation and pharmaceutical compositions containing them
IL63245A0 (en)	1981-10-30	3-aminopropoxyphenyl derivatives,their preparation and pharmaceutical compositions containing them
IL69392A0 (en)	1983-11-30	Nicotinamide derivatives,their preparation and pharmaceutical compositions containing them
IL64555A0 (en)	1982-03-31	Pharmaceutical compositions containing 3-amine-2-pyrazoline derivatives,certain such novel derivatives and their preparation
IL62970A0 (en)	1981-07-31	Substituted phenoxy-aminopropanol derivatives,their preparation and pharmaceutical compositions containing them
IL62519A0 (en)	1981-05-20	Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL63174A0 (en)	1981-09-13	Dibenzindole derivatives,their preparation and pharmaceutical compositions containing them
IL62400A0 (en)	1981-05-20	Thiazole derivatives,their preparation and pharmaceutical compositions containing them
IL63369A (en)	1985-11-29	13-oxa-prostaglandin derivatives,their preparation and pharmaceutical compositions containing them
IL62116A (en)	1986-01-31	Benzylidenimine derivatives,their preparation and pharmaceutical compositions containing them
IL70084A0 (en)	1984-01-31	Pyridine derivatives,their preparation and pharmaceutical compositions containing them