IL47860A - 5,9 -disubstituted 2-tetrahydrofuryl-6,7-benzomorphans andns containing them - Google Patents

5,9 -disubstituted 2-tetrahydrofuryl-6,7-benzomorphans andns containing them

Info

Publication number: IL47860A
Authority: IL; Israel
Prior art keywords: andns; benzomorphans; tetrahydrofuryl; disubstituted; benzomorphans andns
Prior art date: 1974-08-05

Application number

IL47860A

Other languages

English (en)

Other versions

IL47860A0 (en

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-08-05

Filing date

1975-08-04

Publication date

1979-01-31

1975-08-04 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1975-11-25 Publication of IL47860A0 publication Critical patent/IL47860A0/xx

1979-01-31 Publication of IL47860A publication Critical patent/IL47860A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL47860A 1974-08-05 1975-08-04 5,9 -disubstituted 2-tetrahydrofuryl-6,7-benzomorphans andns containing them IL47860A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2437610A DE2437610A1 (de)	1974-08-05	1974-08-05	Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (2)

Publication Number	Publication Date
IL47860A0 IL47860A0 (en)	1975-11-25
IL47860A true IL47860A (en)	1979-01-31

Family

ID=5922448

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL47860A IL47860A (en)	1974-08-05	1975-08-04	5,9 -disubstituted 2-tetrahydrofuryl-6,7-benzomorphans andns containing them

Country Status (27)

Country	Link
US (1)	US3982005A (ja)
JP (1)	JPS60358B2 (ja)
AT (1)	AT348140B (ja)
BE (1)	BE832099R (ja)
BG (3)	BG25090A3 (ja)
CA (1)	CA1049008A (ja)
CH (7)	CH613963A5 (ja)
CS (1)	CS189717B2 (ja)
DD (1)	DD122685A5 (ja)
DE (1)	DE2437610A1 (ja)
DK (1)	DK138992C (ja)
ES (6)	ES452764A1 (ja)
FI (1)	FI63229C (ja)
FR (1)	FR2320096A2 (ja)
GB (1)	GB1513950A (ja)
HU (1)	HU177952B (ja)
IE (1)	IE42216B1 (ja)
IL (1)	IL47860A (ja)
LU (1)	LU73138A1 (ja)
NL (1)	NL7509249A (ja)
NO (1)	NO143460C (ja)
PH (1)	PH13687A (ja)
PL (3)	PL99816B1 (ja)
RO (3)	RO67390A (ja)
SE (1)	SE425392B (ja)
SU (3)	SU591147A3 (ja)
ZA (1)	ZA754997B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4087532A (en) *	1974-03-09	1978-05-02	Boehringer Ingelheim Gmbh	Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1575009A (en) *	1976-06-21	1980-09-17	Acf Chemiefarma Nv	6,7-benzomorphan derivatives
DE2716687A1 (de) *	1977-04-15	1978-10-19	Boehringer Sohn Ingelheim	2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
NL7804509A (nl) *	1978-04-26	1979-10-30	Acf Chemiefarma Nv	Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JPS5636521A (en) *	1979-08-31	1981-04-09	Shin Etsu Chem Co Ltd	Production of alkenyloxy group-containing organopolysiloxane
EP2183228B1 (en)	2007-07-26	2014-08-20	Vitae Pharmaceuticals, Inc.	CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1
WO2009063061A2 (en)	2007-11-16	2009-05-22	Boehringer Ingelheim International Gmbh	Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en)	2007-12-11	2009-06-18	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en)	2008-01-24	2009-07-30	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en)	2008-02-15	2010-12-01	Vitae Pharmaceuticals, Inc.	Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2722427A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (en)	2008-05-01	2013-11-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en)	2008-05-13	2009-12-16	Boehringer Ingelheim Int	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
AU2009274567B2 (en)	2008-07-25	2013-04-04	Boehringer Ingelheim International Gmbh	Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
WO2010010157A2 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
US8680093B2 (en)	2009-04-30	2014-03-25	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en)	2009-06-11	2011-01-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) *	2009-11-06	2011-12-07	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en)	2011-08-17	2014-05-27	Boehringer Ingelheim International Gmbh	Indenopyridine derivatives
EP4253494A1 (en)	2020-11-26	2023-10-04	Shin-Etsu Chemical Co., Ltd.	Room temperature curable organopolysiloxane composition, article, hydrolyzable organosilane compound and method for producing same
KR20240052040A (ko)	2021-09-03	2024-04-22	신에쓰 가가꾸 고교 가부시끼가이샤	오르가노폴리실록산 화합물, 실온 경화성 오르가노폴리실록산 조성물 및 물품

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE582575A (ja) *	1958-09-22
US3700734A (en) *	1969-01-23	1972-10-24	Merck & Co Inc	2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
DE2105743C3 (de) *	1971-02-08	1979-11-29	Boehringer Sohn Ingelheim	2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
CS166802B2 (ja) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim
DE2200596A1 (de) *	1972-01-07	1973-07-12	Boehringer Sohn Ingelheim	N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2217420C3 (de) *	1972-04-12	1981-03-12	C.H. Boehringer Sohn, 6507 Ingelheim	N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) *	1972-06-19	1974-01-31	Boehringer Sohn Ingelheim	2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

1974
- 1974-08-05 DE DE2437610A patent/DE2437610A1/de not_active Ceased
1975
- 1975-07-08 AT AT523775A patent/AT348140B/de not_active IP Right Cessation
- 1975-07-25 SU SU752162235A patent/SU591147A3/ru active
- 1975-07-30 RO RO7583017A patent/RO67390A/ro unknown
- 1975-07-30 US US05/600,374 patent/US3982005A/en not_active Expired - Lifetime
- 1975-07-30 JP JP50092995A patent/JPS60358B2/ja not_active Expired
- 1975-07-31 CH CH1002475A patent/CH613963A5/xx not_active IP Right Cessation
- 1975-07-31 RO RO7593232A patent/RO72735A/ro unknown
- 1975-07-31 RO RO7593231A patent/RO72736A/ro unknown
- 1975-08-01 CA CA75232728A patent/CA1049008A/en not_active Expired
- 1975-08-02 BG BG7500031843A patent/BG25090A3/xx unknown
- 1975-08-02 BG BG7500030726A patent/BG25088A3/xx unknown
- 1975-08-02 BG BG7500031842A patent/BG25089A3/xx unknown
- 1975-08-04 BE BE158924A patent/BE832099R/xx not_active IP Right Cessation
- 1975-08-04 LU LU73138A patent/LU73138A1/xx unknown
- 1975-08-04 GB GB32576/75A patent/GB1513950A/en not_active Expired
- 1975-08-04 PL PL1975190659A patent/PL99816B1/pl unknown
- 1975-08-04 ZA ZA754997A patent/ZA754997B/xx unknown
- 1975-08-04 SE SE7508789A patent/SE425392B/xx not_active IP Right Cessation
- 1975-08-04 FI FI752211A patent/FI63229C/fi not_active IP Right Cessation
- 1975-08-04 IL IL47860A patent/IL47860A/xx unknown
- 1975-08-04 PL PL1975190658A patent/PL99819B1/pl unknown
- 1975-08-04 NL NL7509249A patent/NL7509249A/xx not_active Application Discontinuation
- 1975-08-04 CS CS755425A patent/CS189717B2/cs unknown
- 1975-08-04 NO NO752731A patent/NO143460C/no unknown
- 1975-08-04 PH PH17443A patent/PH13687A/en unknown
- 1975-08-04 DD DD187666A patent/DD122685A5/xx unknown
- 1975-08-04 PL PL1975182528A patent/PL99838B1/pl unknown
- 1975-08-04 DK DK352875A patent/DK138992C/da active
- 1975-08-04 HU HU75BO1566A patent/HU177952B/hu unknown
- 1975-08-05 IE IE1738/75A patent/IE42216B1/en unknown
- 1975-08-05 FR FR7524380A patent/FR2320096A2/fr active Granted
1976
- 1976-04-16 SU SU762346107A patent/SU587858A3/ru active
- 1976-04-16 SU SU762346108A patent/SU587859A3/ru active
- 1976-10-27 ES ES452764A patent/ES452764A1/es not_active Expired
- 1976-10-27 ES ES452766A patent/ES452766A1/es not_active Expired
- 1976-10-27 ES ES452765A patent/ES452765A1/es not_active Expired
- 1976-10-27 ES ES452768A patent/ES452768A1/es not_active Expired
- 1976-10-27 ES ES452763A patent/ES452763A1/es not_active Expired
- 1976-10-27 ES ES452767A patent/ES452767A1/es not_active Expired
1979
- 1979-04-26 CH CH393579A patent/CH616421A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393479A patent/CH615679A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393179A patent/CH615677A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393679A patent/CH615680A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393379A patent/CH616420A5/de not_active IP Right Cessation
- 1979-04-26 CH CH393279A patent/CH615678A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
NL7509249A (nl)	1976-02-09
CH616421A5 (ja)	1980-03-31
ES452765A1 (es)	1977-10-16
CS189717B2 (en)	1979-04-30
FI63229B (fi)	1983-01-31
NO143460C (no)	1981-02-18
DK138992C (da)	1979-04-30
JPS60358B2 (ja)	1985-01-07
RO72736A (ro)	1982-09-09
CH615679A5 (ja)	1980-02-15
ES452768A1 (es)	1977-10-01
DK352875A (da)	1976-02-06
PL99819B1 (pl)	1978-08-31
DE2437610A1 (de)	1976-02-26
NO143460B (no)	1980-11-10
NO752731L (ja)	1976-02-06
PL99816B1 (pl)	1978-08-31
FI752211A (ja)	1976-02-06
ATA523775A (de)	1978-06-15
CH616420A5 (ja)	1980-03-31
PH13687A (en)	1980-09-01
RO67390A (ro)	1981-06-30
SE7508789L (sv)	1976-02-10
ES452763A1 (es)	1977-10-01
PL99838B1 (pl)	1978-08-31
DK138992B (da)	1978-11-27
CH613963A5 (ja)	1979-10-31
HU177952B (en)	1982-02-28
IE42216L (en)	1976-02-05
DD122685A5 (ja)	1976-10-20
BE832099R (fr)	1976-02-04
US3982005A (en)	1976-09-21
FI63229C (fi)	1983-05-10
AU8364675A (en)	1977-02-10
IL47860A0 (en)	1975-11-25
IE42216B1 (en)	1980-07-02
CH615678A5 (ja)	1980-02-15
ES452764A1 (es)	1977-10-16
ES452767A1 (es)	1977-10-01
ZA754997B (en)	1977-04-27
CH615677A5 (ja)	1980-02-15
FR2320096B2 (ja)	1978-09-01
CA1049008A (en)	1979-02-20
BG25089A3 (en)	1978-07-12
SU591147A3 (ru)	1978-01-30
SU587858A3 (ru)	1978-01-05
FR2320096A2 (fr)	1977-03-04
ES452766A1 (es)	1977-10-01
SE425392B (sv)	1982-09-27
LU73138A1 (ja)	1977-04-13
JPS5139673A (en)	1976-04-02
SU587859A3 (ru)	1978-01-05
AT348140B (de)	1979-01-25
CH615680A5 (ja)	1980-02-15
RO72735A (ro)	1982-09-09
BG25088A3 (en)	1978-07-12
BG25090A3 (en)	1978-07-12
GB1513950A (en)	1978-06-14

Publication	Publication Date	Title
IL47860A (en)	1979-01-31	5,9 -disubstituted 2-tetrahydrofuryl-6,7-benzomorphans andns containing them
IL53485A0 (en)	1978-01-31	2,3-dioxypiperazine derivatives
ZA751193B (en)	1976-04-28	1,1-diaryl-1-oxadiazol-alkylamines
AU7742875A (en)	1976-07-22	New phenol-acetals
EG11730A (en)	1978-03-29	New thiatiazolylimidazolidinones
GB1517973A (en)	1978-07-19	6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
AU8483675A (en)	1977-03-24	Polyhydroxy-alkyl-3,5-disubstituted-2, 4,6-triiodo-carbanilates
IE42364L (en)	1976-06-03	Hydroxyphenylacetonitriles.
ATA392274A (de)	1975-11-15	Einrichtung zum antrieb einer durchbiegungsausgleichwalze
ZA75254B (en)	1976-01-28	17 alpha-ethynyl (5-alpha), 2-androsten, 17 beta-ol
KE2924A (en)	1979-04-06	2,3-dioyopiperazine derivatives
GB1487457A (en)	1977-09-28	5,7-dihydroxy-tetraisoquinoline derivatives
ZA75954B (en)	1976-01-28	1,2,4-triazolidin-3-ones
GB1520905A (en)	1978-08-09	1,3,4-thiadiazole-2-ylureas
ZA756191B (en)	1976-09-29	1,4-oxazepines
GB1516534A (en)	1978-07-05	Basically substituted 3,4-dihydro-2h-isoquinolin-1-thione
IL47507A0 (en)	1975-08-31	2,-3-dihydroestra-1,3,5(10)-trieno-(16alpha,17alpha-beta)furan-17beta-ols
NZ178880A (en)	1978-06-20	13-alkyl-d-jomogon-(4,16-or5(10),16)-dien-17 -ols
AU498671B2 (en)	1979-03-22	1-aryl-2-oxo-hexahydro-2,4,5,6,7,7a-indoles
IL47487A0 (en)	1975-08-31	9-thia-or oxothia-and dioxothia-11,12-seco-prostaglandins
IE41250B1 (en)	1979-11-21	2,2-bis-hydroxymethylalkanesulphonates
PH11939A (en)	1978-09-15	5,6-dibenzyloxy-2-aminotetralol derivatives
ZA751663B (en)	1976-02-25	N-substitute 1,2,4-triazoles
PH13018A (en)	1979-11-09	1,2,4-triazolidin-2-ones
CA1029373A (en)	1978-04-11	1,2,4-dithiaaz-3-enes