IL173206A0 - Heparin-derived oligosaccharide mixtures, preparation thereof and pharmaceutical compositions containing said mixtures - Google Patents

Heparin-derived oligosaccharide mixtures, preparation thereof and pharmaceutical compositions containing said mixtures

Info

Publication number
IL173206A0
IL173206A0 IL173206A IL17320606A IL173206A0 IL 173206 A0 IL173206 A0 IL 173206A0 IL 173206 A IL173206 A IL 173206A IL 17320606 A IL17320606 A IL 17320606A IL 173206 A0 IL173206 A0 IL 173206A0
Authority
IL
Israel
Prior art keywords
mixtures
heparin
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL173206A
Other versions
IL173206A (en
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of IL173206A0 publication Critical patent/IL173206A0/en
Publication of IL173206A publication Critical patent/IL173206A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078Degradation products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL173206A 2003-07-24 2006-01-17 Heparin-derived oligosaccharide mixtures, preparation thereof and pharmaceutical compositions containing said mixtures IL173206A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0309041A FR2857971B1 (en) 2003-07-24 2003-07-24 MIXTURES OF HEPARIN DERIVED OLIGOSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR2004/001943 WO2005010051A2 (en) 2003-07-24 2004-07-22 Heparin-derived oligosaccharide mixtures, preparation thereof and pharmaceutical compositions containing said mixtures

Publications (2)

Publication Number Publication Date
IL173206A0 true IL173206A0 (en) 2006-06-11
IL173206A IL173206A (en) 2010-11-30

Family

ID=33561051

Family Applications (1)

Application Number Title Priority Date Filing Date
IL173206A IL173206A (en) 2003-07-24 2006-01-17 Heparin-derived oligosaccharide mixtures, preparation thereof and pharmaceutical compositions containing said mixtures

Country Status (40)

Country Link
EP (1) EP1651677B1 (en)
JP (1) JP4865552B2 (en)
KR (1) KR101125517B1 (en)
CN (1) CN1852926B (en)
AR (1) AR045917A1 (en)
AT (1) ATE487741T1 (en)
AU (1) AU2004259111B2 (en)
BR (1) BRPI0412850A (en)
CA (1) CA2533555A1 (en)
CR (1) CR8201A (en)
CY (1) CY1111165T1 (en)
DE (1) DE602004030015D1 (en)
DK (1) DK1651677T3 (en)
EC (1) ECSP066305A (en)
ES (1) ES2355827T3 (en)
FR (1) FR2857971B1 (en)
GT (1) GT200400145A (en)
HK (1) HK1094806A1 (en)
HN (1) HN2004000250A (en)
IL (1) IL173206A (en)
MA (1) MA27928A1 (en)
ME (1) MEP11608A (en)
MX (1) MXPA06000336A (en)
MY (1) MY136769A (en)
NO (1) NO20060821L (en)
NZ (1) NZ544717A (en)
OA (1) OA13197A (en)
PA (1) PA8606801A1 (en)
PE (1) PE20050246A1 (en)
PL (1) PL1651677T3 (en)
PT (1) PT1651677E (en)
RS (1) RS20060044A (en)
RU (1) RU2346005C2 (en)
SI (1) SI1651677T1 (en)
TN (1) TNSN06025A1 (en)
TW (1) TWI369208B (en)
UA (1) UA89356C2 (en)
UY (1) UY28435A1 (en)
WO (1) WO2005010051A2 (en)
ZA (1) ZA200600657B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7589145B2 (en) 2004-04-15 2009-09-15 Exxonmobil Chemical Patents Inc. Syndiotactic rich polyolefins
WO2007140231A2 (en) * 2006-05-25 2007-12-06 Momenta Pharmaceutical, Inc. Low molecular weight heparin composition and uses thereof
CN101711771B (en) * 2008-10-07 2015-12-09 上海喜恩医药科技发展有限公司 A kind of polysaccharide mixture of heparin derivative and method for making thereof and pharmaceutical composition
WO2012036152A1 (en) * 2010-09-14 2012-03-22 国立大学法人 宮崎大学 High purity heparin and production method therefor
WO2012072799A1 (en) 2010-12-02 2012-06-07 Aventis Pharma S.A. New methods for the in vitro measurement of the biological activity of an ultra low molecular weight heparin sample
CN102558392A (en) * 2010-12-14 2012-07-11 王芃 Preparation method of high-FXa-resistant low-FIIa-resistant low-molecular heparin sodium
CN102816255B (en) * 2011-06-10 2015-11-25 王芃 A kind of preparation method of ultra-low molecular heparin sodium
US9896517B2 (en) 2013-03-26 2018-02-20 Jiuzhitang Co., Ltd. Low molecular weight glycosaminoglycan derivative, pharmaceutical composition thereof, preparation method therefor and use thereof
CN103864959A (en) * 2014-04-03 2014-06-18 中国药科大学 Application of heparin oligosaccharide dp12 in atherosclerosis resistance
RU2639574C2 (en) * 2016-05-23 2017-12-21 Алексей Георгиевич Александров Process for low molecular weight heparin preparation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
FR2504928A1 (en) * 1981-04-29 1982-11-05 Choay Sa SHORT CHAIN OLIGOSACCHARIDES HAVING BIOLOGICAL PROPERTIES, PREPARATION THEREOF AND APPLICATIONS THEREOF AS MEDICAMENTS
EP0986581A1 (en) * 1997-06-06 2000-03-22 Hamilton Civic Hospitals Research Development, Inc. Modified low molecular weight heparin that inhibits clot associated coagulation factors
JP4897991B2 (en) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ Ultra low molecular weight heparin composition
ES2161615B1 (en) * 1999-07-23 2003-03-16 Rovi Lab Farmaceut Sa COMPOSITIONS OF HEPARINS OF VERY LOW MOLECULAR WEIGHT.
FR2800074B1 (en) * 1999-10-22 2001-12-21 Aventis Pharma Sa NOVEL OLIGOSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JP4585072B2 (en) * 2000-02-29 2010-11-24 扶桑薬品工業株式会社 Heparin depolymerization method, depolymerized heparin, derivatives thereof and pharmaceutical composition
FR2807043B1 (en) * 2000-03-28 2002-11-22 Aventis Pharma Sa PHARMACEUTICAL COMPOSITION CONTAINING OLIGOSACCHARIDES, NEW OLIGOSACCHARIDES AND THEIR PREPARATION
FR2811992B1 (en) * 2000-07-21 2003-07-04 Aventis Pharma Sa MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6969705B2 (en) * 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
JP2005505537A (en) * 2001-08-28 2005-02-24 レオ・ファーマ・アクティーゼルスカブ Antithrombotic composition comprising low molecular weight heparin and low molecular weight dermatan sulfate
FR2845686B1 (en) * 2002-10-10 2013-08-30 Aventis Pharma Sa MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
SI1651677T1 (en) 2011-03-31
HN2004000250A (en) 2006-06-29
TNSN06025A1 (en) 2007-10-03
MY136769A (en) 2008-11-28
CR8201A (en) 2006-09-22
OA13197A (en) 2006-12-13
WO2005010051A3 (en) 2005-06-16
MEP11608A (en) 2010-06-10
PE20050246A1 (en) 2005-06-02
FR2857971B1 (en) 2005-08-26
ECSP066305A (en) 2006-07-28
PA8606801A1 (en) 2005-02-04
BRPI0412850A (en) 2006-10-03
TWI369208B (en) 2012-08-01
AU2004259111A1 (en) 2005-02-03
GT200400145A (en) 2005-03-16
KR20060059974A (en) 2006-06-02
HK1094806A1 (en) 2007-04-13
PT1651677E (en) 2011-02-08
WO2005010051A2 (en) 2005-02-03
IL173206A (en) 2010-11-30
RS20060044A (en) 2008-06-05
NO20060821L (en) 2006-04-20
PL1651677T3 (en) 2011-04-29
ZA200600657B (en) 2007-05-30
CA2533555A1 (en) 2005-02-03
JP4865552B2 (en) 2012-02-01
TW200522970A (en) 2005-07-16
JP2006528614A (en) 2006-12-21
NZ544717A (en) 2009-09-25
EP1651677A2 (en) 2006-05-03
CY1111165T1 (en) 2015-06-11
MA27928A1 (en) 2006-06-01
RU2346005C2 (en) 2009-02-10
DE602004030015D1 (en) 2010-12-23
CN1852926A (en) 2006-10-25
MXPA06000336A (en) 2006-03-30
EP1651677B1 (en) 2010-11-10
AR045917A1 (en) 2005-11-16
ES2355827T3 (en) 2011-03-31
KR101125517B1 (en) 2012-03-23
RU2006105384A (en) 2007-09-10
DK1651677T3 (en) 2011-02-28
ATE487741T1 (en) 2010-11-15
AU2004259111B2 (en) 2009-06-11
FR2857971A1 (en) 2005-01-28
CN1852926B (en) 2010-05-12
UA89356C2 (en) 2010-01-25
UY28435A1 (en) 2005-02-28

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees