IL148816A0 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number: IL148816A0
Authority: IL; Israel
Prior art keywords: benzodiazepine derivatives; benzodiazepine; derivatives
Prior art date: 1999-10-15

Application number

IL14881600A

Other languages

English (en)

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-15

Filing date

2000-09-29

Publication date

2002-09-12

2000-09-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2002-09-12 Publication of IL148816A0 publication Critical patent/IL148816A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Otolaryngology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL14881600A 1999-10-15 2000-09-29 Benzodiazepine derivatives IL148816A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99120520		1999-10-15
PCT/EP2000/009553 WO2001029011A2 (en)	1999-10-15	2000-09-29	Benzodiazepine derivatives as metabotropic glutamate receptor antagonists

Publications (1)

Publication Number	Publication Date
IL148816A0 true IL148816A0 (en)	2002-09-12

Family

ID=8239207

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL14881600A IL148816A0 (en)	1999-10-15	2000-09-29	Benzodiazepine derivatives
IL148816A IL148816A (en)	1999-10-15	2002-03-21	Derivatives of benzodiazepine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL148816A IL148816A (en)	1999-10-15	2002-03-21	Derivatives of benzodiazepine

Country Status (35)

Country	Link
US (1)	US6407094B1 (pt)
EP (1)	EP1224174B1 (pt)
JP (1)	JP3857138B2 (pt)
KR (1)	KR100480320B1 (pt)
CN (1)	CN1195522C (pt)
AR (1)	AR026029A1 (pt)
AT (1)	ATE250039T1 (pt)
AU (1)	AU774451B2 (pt)
BR (1)	BR0014859A (pt)
CA (1)	CA2386974C (pt)
CO (1)	CO5261604A1 (pt)
CZ (1)	CZ20021653A3 (pt)
DE (1)	DE60005386T2 (pt)
DK (1)	DK1224174T3 (pt)
EG (1)	EG24079A (pt)
ES (1)	ES2204704T3 (pt)
GC (1)	GC0000263A (pt)
HK (1)	HK1051038A1 (pt)
HR (1)	HRP20020259A2 (pt)
HU (1)	HUP0203142A3 (pt)
IL (2)	IL148816A0 (pt)
JO (1)	JO2262B1 (pt)
MA (1)	MA26831A1 (pt)
MY (1)	MY125540A (pt)
NO (1)	NO327817B1 (pt)
NZ (1)	NZ517999A (pt)
PE (1)	PE20010681A1 (pt)
PL (1)	PL357418A1 (pt)
PT (1)	PT1224174E (pt)
RU (1)	RU2259360C2 (pt)
SI (1)	SI1224174T1 (pt)
TR (1)	TR200201023T2 (pt)
WO (1)	WO2001029011A2 (pt)
YU (1)	YU26202A (pt)
ZA (1)	ZA200202544B (pt)

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RU2257382C2 (ru)	1999-10-15	2005-07-27	Ф.Хоффманн-Ля Рош Аг	Производные бензодиазепина, лекарственное средство, содержащее их, и способ их получения
AU2002312788B2 (en) *	2001-04-12	2005-11-10	F. Hoffmann-La Roche Ag	Dihydro-benzo [b] [1, 4] diazepin-2-one derivatives as mGluR2 antagonists II
ES2235044T3 (es) *	2001-04-12	2005-07-01	F. Hoffmann-La Roche Ag	Derivados de dihidro-benzo (b) (1,4)-diazepin-2-ona como antagonistas i de mglur2.
US20070122353A1 (en)	2001-05-24	2007-05-31	Hale Ron L	Drug condensation aerosols and kits
US20030051728A1 (en)	2001-06-05	2003-03-20	Lloyd Peter M.	Method and device for delivering a physiologically active compound
US6949542B2 (en) *	2002-02-06	2005-09-27	Hoffman-La Roche Inc.	Dihydro-benzo[b][1,4]diazepin-2-one derivatives
BR0314192A (pt) *	2002-09-10	2005-07-26	Novartis Ag	Antagonistas de receptores de mglu para tratamento de distúrbios associados com receptores de mglu incluindo vìcio e depressão
CA2526475A1 (en)	2003-05-21	2004-12-02	Alexza Pharmaceuticals, Inc.	Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
ATE374030T1 (de) *	2003-07-25	2007-10-15	Hoffmann La Roche	Kombination eines mglur2 antagonists und eines ache inhibitors zur behandlung von akuten und/oder chronischen neurologischen krankheiten
FR2862969A1 (fr)	2003-11-28	2005-06-03	Oreal	Procede de preparation de derives paraphenylenediamine a groupement pyrrolidinyle, substitue par un radical azote, et composes intermediaires
DE102004010893A1 (de) *	2004-03-06	2005-09-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
WO2006048172A1 (en)	2004-11-05	2006-05-11	F. Hoffmann-La Roche Ag	Process for preparation of isonicotinic acid derivatives
AP2007004047A0 (en)	2005-01-20	2007-06-30	Pfizer Ltd	Substituted triazole derivatives as oxtocin antagonists
AR059898A1 (es) *	2006-03-15	2008-05-07	Janssen Pharmaceutica Nv	Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en)	2007-03-07	2009-01-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en)	2007-03-07	2008-12-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
US20080216828A1 (en)	2007-03-09	2008-09-11	Alexza Pharmaceuticals, Inc.	Heating unit for use in a drug delivery device
JP2010524879A (ja)	2007-04-19	2010-07-22	エフ．ホフマン−ラロシュアーゲー	ジヒドロ−ベンゾ［ｂ］［１，４］ジアゼピン−２−オンスルホンアミド誘導体
CN103342695B (zh)	2007-09-14	2015-04-22	杨森制药有限公司	1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮
AU2008297876B2 (en)	2007-09-14	2011-07-07	Addex Pharma S.A.	1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
ES2409215T3 (es) *	2007-09-14	2013-06-25	Janssen Pharmaceuticals, Inc.	4-fenil-1H-piridin-2-onas 1-3-disustituidas
US8158605B2 (en) *	2007-09-26	2012-04-17	Mount Sinai School Of Medicine	Azacytidine analogues and uses thereof
JP5433582B2 (ja) *	2007-11-14	2014-03-05	ジャンセンファーマシューティカルズ，インコーポレイテッド．	イミダゾ［１，２−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体の正のアロステリック調節因子としてのその使用
BRPI0918055A2 (pt)	2008-09-02	2015-12-01	Addex Pharmaceuticals Sa	derivados de 3-azabiciclo[3,1,0]hexila como moduladores de receptores metabotrópicos de glutamato.
CN102186477B (zh)	2008-10-16	2013-07-17	奥梅-杨森制药有限公司	作为代谢型谷氨酸受体调节剂的吲哚和苯并吗啉衍生物
MX2011005242A (es)	2008-11-28	2011-09-06	Ortho Mcneil Janssen Pharm	Derivados de indol y benzoxazina como moduladores de los receptores de glutamato metabotropicos.
MY161325A (en)	2009-05-12	2017-04-14	Janssen Pharmaceuticals Inc	1, 2, 4-triazolo[4,3-a]pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders
AR076859A1 (es)	2009-05-12	2011-07-13	Ortho Mcneil Janssen Pharm	Derivados de 1,2,4-triazolo[4,3-a]piridina moduladores alostericos positivos de receptores mglur2 , composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de trastornos neurologicos y siquiatricos.
MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN101891706B (zh) *	2010-04-09	2013-05-29	复旦大学	3,4-二氢苯并[f][1,4]噻氮杂*类化合物或其盐及其药物用途
WO2012015024A1 (ja)	2010-07-29	2012-02-02	大正製薬株式会社	エチニル－ピラゾール誘導体
ES2536433T3 (es)	2010-11-08	2015-05-25	Janssen Pharmaceuticals, Inc.	Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
WO2012062750A1 (en)	2010-11-08	2012-05-18	Janssen Pharmaceuticals, Inc.	1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
ES2552879T3 (es)	2010-11-08	2015-12-02	Janssen Pharmaceuticals, Inc.	Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
JP2012153674A (ja) *	2011-01-28	2012-08-16	Astellas Pharma Inc	ジ（アリールアミノ）アリール化合物の製造方法及びその合成中間体
WO2014064028A1 (en)	2012-10-23	2014-05-01	F. Hoffmann-La Roche Ag	Mglu2/3 antagonists for the treatment of autistic disorders
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
CN106061504B (zh)	2014-01-21	2019-09-06	詹森药业有限公司	包括代谢型谷氨酸能受体亚型2的正别构调节物或正位激动剂的组合及其用途
KR20200126026A (ko)	2014-01-21	2020-11-05	얀센 파마슈티카 엔.브이.	대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
US9895324B2 (en)	2014-03-26	2018-02-20	University Of Kentucky Research Foundation	Halogenated diarylacetylenes and methods of treating cancer
RU2016144702A (ru)	2014-04-23	2018-05-24	Ф. Хоффманн-Ля Рош Аг	Антагонисты mglu2/3 для лечения интеллектуальной недостаточности
EP3154954B1 (en)	2014-06-10	2022-02-09	Sanford-Burnham Medical Research Institute	Metabotropic glutamate receptor negative allosteric modulators (nams) and uses thereof
CN106243050B (zh) *	2016-08-10	2019-09-06	安徽恒星制药有限公司	一种适合工业化生产氯巴占的方法
CN109836356B (zh) *	2017-11-24	2022-03-08	沈阳化工研究院有限公司	一种芳甲醚衍生物及其应用
RU2702358C1 (ru) *	2019-06-04	2019-10-08	Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук	Способ получения 2,2,4-триалкил-2,3-дигидро-1Н-1,5-бензодиазепинов
CN114349779B (zh) *	2021-12-29	2023-09-26	智仑超纯环氧树脂(西安)有限公司	一种改性二氧化硅颗粒除氯剂及其制备方法及应用

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Publication number	Priority date	Publication date	Assignee	Title
WO1997005109A1 (en) *	1995-07-31	1997-02-13	Novo Nordisk A/S	Heterocyclic compounds, their preparation and use
AU771358B2 (en) *	1997-11-21	2004-03-18	Astrazeneca Ab	Metabotropic glutamate receptor antagonists for treating central nervous system diseases

2000
- 2000-09-29 EP EP00969347A patent/EP1224174B1/en not_active Expired - Lifetime
- 2000-09-29 AT AT00969347T patent/ATE250039T1/de not_active IP Right Cessation
- 2000-09-29 IL IL14881600A patent/IL148816A0/xx active IP Right Grant
- 2000-09-29 ES ES00969347T patent/ES2204704T3/es not_active Expired - Lifetime
- 2000-09-29 SI SI200030210T patent/SI1224174T1/xx unknown
- 2000-09-29 NZ NZ517999A patent/NZ517999A/en unknown
- 2000-09-29 HU HU0203142A patent/HUP0203142A3/hu unknown
- 2000-09-29 CN CNB008142742A patent/CN1195522C/zh not_active Expired - Fee Related
- 2000-09-29 KR KR10-2002-7004838A patent/KR100480320B1/ko not_active IP Right Cessation
- 2000-09-29 CZ CZ20021653A patent/CZ20021653A3/cs unknown
- 2000-09-29 TR TR2002/01023T patent/TR200201023T2/xx unknown
- 2000-09-29 CA CA002386974A patent/CA2386974C/en not_active Expired - Fee Related
- 2000-09-29 PL PL00357418A patent/PL357418A1/xx unknown
- 2000-09-29 YU YU26202A patent/YU26202A/sh unknown
- 2000-09-29 WO PCT/EP2000/009553 patent/WO2001029011A2/en active IP Right Grant
- 2000-09-29 DK DK00969347T patent/DK1224174T3/da active
- 2000-09-29 RU RU2002110104/04A patent/RU2259360C2/ru not_active IP Right Cessation
- 2000-09-29 JP JP2001531811A patent/JP3857138B2/ja not_active Expired - Fee Related
- 2000-09-29 DE DE60005386T patent/DE60005386T2/de not_active Expired - Lifetime
- 2000-09-29 BR BR0014859-8A patent/BR0014859A/pt not_active Application Discontinuation
- 2000-09-29 AU AU79102/00A patent/AU774451B2/en not_active Ceased
- 2000-09-29 PT PT00969347T patent/PT1224174E/pt unknown
- 2000-10-10 JO JO2000169A patent/JO2262B1/en active
- 2000-10-10 PE PE2000001083A patent/PE20010681A1/es not_active Application Discontinuation
- 2000-10-11 GC GCP2000950 patent/GC0000263A/en active
- 2000-10-12 CO CO00077957A patent/CO5261604A1/es not_active Application Discontinuation
- 2000-10-13 MY MYPI20004817A patent/MY125540A/en unknown
- 2000-10-13 AR ARP000105386A patent/AR026029A1/es unknown
- 2000-10-13 US US09/687,240 patent/US6407094B1/en not_active Expired - Fee Related
- 2000-10-14 EG EG20001310A patent/EG24079A/xx active
2002
- 2002-03-21 IL IL148816A patent/IL148816A/en not_active IP Right Cessation
- 2002-03-27 HR HR20020259A patent/HRP20020259A2/xx not_active Application Discontinuation
- 2002-03-28 ZA ZA200202544A patent/ZA200202544B/xx unknown
- 2002-04-10 NO NO20021690A patent/NO327817B1/no not_active IP Right Cessation
- 2002-04-15 MA MA26601A patent/MA26831A1/fr unknown
2003
- 2003-04-17 HK HK03102802A patent/HK1051038A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2386974C (en)	2009-10-13
ZA200202544B (en)	2003-09-23
CN1195522C (zh)	2005-04-06
DE60005386D1 (de)	2003-10-23
KR20020038954A (ko)	2002-05-24
CA2386974A1 (en)	2001-04-26
JP3857138B2 (ja)	2006-12-13
NO20021690D0 (no)	2002-04-10
KR100480320B1 (ko)	2005-04-07
CZ20021653A3 (cs)	2002-08-14
WO2001029011A2 (en)	2001-04-26
IL148816A (en)	2006-10-31
DE60005386T2 (de)	2004-06-24
RU2259360C2 (ru)	2005-08-27
JP2003512359A (ja)	2003-04-02
GC0000263A (en)	2006-11-01
TR200201023T2 (tr)	2002-09-23
AU7910200A (en)	2001-04-30
CO5261604A1 (es)	2003-03-31
DK1224174T3 (da)	2004-01-26
ES2204704T3 (es)	2004-05-01
ATE250039T1 (de)	2003-10-15
PL357418A1 (en)	2004-07-26
HUP0203142A2 (hu)	2003-02-28
AR026029A1 (es)	2002-12-26
AU774451B2 (en)	2004-06-24
SI1224174T1 (en)	2003-12-31
PE20010681A1 (es)	2001-06-28
HUP0203142A3 (en)	2003-03-28
NO327817B1 (no)	2009-09-28
WO2001029011A3 (en)	2001-11-08
BR0014859A (pt)	2002-07-16
EG24079A (en)	2008-05-11
HRP20020259A2 (en)	2004-04-30
MA26831A1 (fr)	2004-12-20
EP1224174A2 (en)	2002-07-24
MY125540A (en)	2006-08-30
JO2262B1 (en)	2004-10-07
NO20021690L (no)	2002-04-10
EP1224174B1 (en)	2003-09-17
HK1051038A1 (en)	2003-07-18
PT1224174E (pt)	2004-01-30
YU26202A (sh)	2004-12-31
US6407094B1 (en)	2002-06-18
CN1379765A (zh)	2002-11-13
NZ517999A (en)	2004-07-30

Legal Events

Date	Code	Title	Description
2007-06-17	FF	Patent granted
2007-06-17	KB	Patent renewed

Publication	Publication Date	Title
GC0000207A (en)	2006-03-29	Benzodiazepine derivatives
EG24079A (en)	2008-05-11	Benzodiazepine derivatives
EG23817A (en)	2007-09-19	4-Phenyl-pyridine derivatives
HUP0201535A2 (en)	2002-08-28	5-cyano-2-aminopyrimidine derivatives
IL148167A0 (en)	2002-09-12	Amino-triazolopyridine derivatives
GC0000183A (en)	2006-03-29	3-Phenyl-pyridine derivatives
IL145739A0 (en)	2002-07-25	13-methyl-erythromycin derivatives
GC0000338A (en)	2007-03-31	5-Phenyl-pyrimidine derivatives
IL148837A0 (en)	2002-09-12	Isoxazolecarboxamide derivatives
GC0000191A (en)	2006-03-29	4-Phenyl-pyrimidine derivatives
IL155035A0 (en)	2003-10-31	Benzodiazepine derivatives
IL147636A0 (en)	2002-08-14	3-amino-2-benzyl-1-phenyl-propane derivatives
GB9925880D0 (en)	1999-12-29	B-Carboline derivatives
IL150132A0 (en)	2002-12-01	Cyclopenteneone derivatives
GC0000256A (en)	2006-11-01	Ethanesulfonyl-piperidine derivatives
AP2001002327A0 (en)	2001-12-31	1-Trifluoromethyl-4-hydroxy-7- piperidinylaminomethy lchroman derivatives
PL351407A1 (en)	2003-04-22	Thio-oxindole derivatives
IL146282A0 (en)	2002-07-25	Thio-oxindole derivatives
GB9907134D0 (en)	1999-05-19	Antimor napthylcombretastatin derivatives
HK1043987A1 (zh)	2002-10-04	硫-羥吲衍生物