HRP20020259A2 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number: HRP20020259A2
Authority: HR; Croatia
Prior art keywords: benzodiazepine derivatives; benzodiazepine; derivatives
Prior art date: 1999-10-15

Application number

HR20020259A

Other languages

English (en)

Inventor

Geo Adam

Alexander Alanine

Erwin Goetschi

Vincent Mutel

Thomas Johannes Woltering

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-15

Filing date

2002-03-27

Publication date

2004-04-30

2002-03-27 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2004-04-30 Publication of HRP20020259A2 publication Critical patent/HRP20020259A2/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Otolaryngology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

HR20020259A 1999-10-15 2002-03-27 Benzodiazepine derivatives HRP20020259A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99120520		1999-10-15
PCT/EP2000/009553 WO2001029011A2 (en)	1999-10-15	2000-09-29	Benzodiazepine derivatives as metabotropic glutamate receptor antagonists

Publications (1)

Publication Number	Publication Date
HRP20020259A2 true HRP20020259A2 (en)	2004-04-30

Family

ID=8239207

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20020259A HRP20020259A2 (en)	1999-10-15	2002-03-27	Benzodiazepine derivatives

Country Status (35)

Country	Link
US (1)	US6407094B1 (xx)
EP (1)	EP1224174B1 (xx)
JP (1)	JP3857138B2 (xx)
KR (1)	KR100480320B1 (xx)
CN (1)	CN1195522C (xx)
AR (1)	AR026029A1 (xx)
AT (1)	ATE250039T1 (xx)
AU (1)	AU774451B2 (xx)
BR (1)	BR0014859A (xx)
CA (1)	CA2386974C (xx)
CO (1)	CO5261604A1 (xx)
CZ (1)	CZ20021653A3 (xx)
DE (1)	DE60005386T2 (xx)
DK (1)	DK1224174T3 (xx)
EG (1)	EG24079A (xx)
ES (1)	ES2204704T3 (xx)
GC (1)	GC0000263A (xx)
HK (1)	HK1051038A1 (xx)
HR (1)	HRP20020259A2 (xx)
HU (1)	HUP0203142A3 (xx)
IL (2)	IL148816A0 (xx)
JO (1)	JO2262B1 (xx)
MA (1)	MA26831A1 (xx)
MY (1)	MY125540A (xx)
NO (1)	NO327817B1 (xx)
NZ (1)	NZ517999A (xx)
PE (1)	PE20010681A1 (xx)
PL (1)	PL357418A1 (xx)
PT (1)	PT1224174E (xx)
RU (1)	RU2259360C2 (xx)
SI (1)	SI1224174T1 (xx)
TR (1)	TR200201023T2 (xx)
WO (1)	WO2001029011A2 (xx)
YU (1)	YU26202A (xx)
ZA (1)	ZA200202544B (xx)

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CN1199954C (zh)	1999-10-15	2005-05-04	弗·哈夫曼-拉罗切有限公司	苯并二氮杂䓬衍生物
HUP0400991A3 (en) *	2001-04-12	2009-06-29	Hoffmann La Roche	Dihydro-benzo[b][1,4]diazepin-2-one derivatives as mglur2 antagonists i, process for their preparation and pharmaceutical compositions containing them
CZ20033003A3 (cs)	2001-04-12	2004-05-12	F@Áhoffmann@Laárocheáag	Dihydrobenzo [b][�Ź@]diazepin@onové deriváty jako MGLUR@ antagonisty II
US20030051728A1 (en)	2001-06-05	2003-03-20	Lloyd Peter M.	Method and device for delivering a physiologically active compound
US20070122353A1 (en)	2001-05-24	2007-05-31	Hale Ron L	Drug condensation aerosols and kits
US6949542B2 (en)	2002-02-06	2005-09-27	Hoffman-La Roche Inc.	Dihydro-benzo[b][1,4]diazepin-2-one derivatives
US8354447B2 (en) *	2002-09-10	2013-01-15	The Scripps Research Institute	mGLU receptors antagonists for treating disorders associated with mGLU receptors including addiction and depression
ATE510174T1 (de)	2003-05-21	2011-06-15	Alexza Pharmaceuticals Inc	Schlag gezündete unabhängige heizeinheit
BRPI0412919A (pt) *	2003-07-25	2006-09-26	Hoffmann La Roche	combinação de antagonista de mglur2 e inibidor de ache para o tratamento de distúrbios neurológicos crÈnicos e/ou agudos
FR2862969A1 (fr)	2003-11-28	2005-06-03	Oreal	Procede de preparation de derives paraphenylenediamine a groupement pyrrolidinyle, substitue par un radical azote, et composes intermediaires
DE102004010893A1 (de) *	2004-03-06	2005-09-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
US7459563B2 (en)	2004-11-05	2008-12-02	Hoffmann-La Roche Inc.	Process for the preparation of isonicotinic acid derivatives
AP2007004047A0 (en)	2005-01-20	2007-06-30	Pfizer Ltd	Substituted triazole derivatives as oxtocin antagonists
TWI417095B (zh) *	2006-03-15	2013-12-01	Janssen Pharmaceuticals Inc	１，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
TW200900065A (en)	2007-03-07	2009-01-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en)	2007-03-07	2008-12-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
ES2594867T3 (es)	2007-03-09	2016-12-23	Alexza Pharmaceuticals, Inc.	Unidad de calentamiento para usar en un dispositivo de administración de fármaco
EP2137167B1 (en) *	2007-04-19	2011-08-10	F. Hoffmann-La Roche AG	Dihydro-benzo[b][1,4]diazepin-2-one sulfonamide derivatives
TW200927731A (en) *	2007-09-14	2009-07-01	Ortho Mcneil Janssen Pharm	1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
EA019085B1 (ru)	2007-09-14	2014-01-30	Янссен Фармасьютикалз, Инк.	1',3-двузамещенные 4-(арил-х-фенил)-1н-пиридин-2-оны
US9114138B2 (en)	2007-09-14	2015-08-25	Janssen Pharmaceuticals, Inc.	1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones
RU2488591C2 (ru) *	2007-09-26	2013-07-27	Маунт Синай Скул Оф Медсин	Аналоги азацитидина и их применение
JP5433582B2 (ja) *	2007-11-14	2014-03-05	ジャンセンファーマシューティカルズ，インコーポレイテッド．	イミダゾ［１，２−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体の正のアロステリック調節因子としてのその使用
WO2010025890A1 (en)	2008-09-02	2010-03-11	Ortho-Mcneil-Janssen Pharmaceuticals, Inc	3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
AU2009304293B2 (en)	2008-10-16	2012-04-26	Addex Pharma S.A.	Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
AU2009319387B2 (en)	2008-11-28	2012-05-10	Addex Pharma S.A.	Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
JP5634506B2 (ja)	2009-05-12	2014-12-03	ジャンセンファーマシューティカルズ，インコーポレイテッド	１，２，３−トリアゾロ［４，３−ａ］ピリジン誘導体ならびに神経障害および精神障害の治療または予防のためのその使用
MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CA2760259C (en)	2009-05-12	2018-05-01	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN101891706B (zh) *	2010-04-09	2013-05-29	复旦大学	3,4-二氢苯并[f][1,4]噻氮杂*类化合物或其盐及其药物用途
EP2599775A4 (en)	2010-07-29	2014-04-30	Taisho Pharmaceutical Co Ltd	ETHINYLPYRAZOLDERIVAT
JP5852665B2 (ja)	2010-11-08	2016-02-03	ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド	１，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
ES2552455T3 (es)	2010-11-08	2015-11-30	Janssen Pharmaceuticals, Inc.	Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
JP5852666B2 (ja)	2010-11-08	2016-02-03	ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド	１，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
JP2012153674A (ja) *	2011-01-28	2012-08-16	Astellas Pharma Inc	ジ（アリールアミノ）アリール化合物の製造方法及びその合成中間体
CN104736140A (zh)	2012-10-23	2015-06-24	霍夫曼-拉罗奇有限公司	用于治疗自闭症的mGlu2/3拮抗剂
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
LT3096790T (lt)	2014-01-21	2019-10-10	Janssen Pharmaceutica, N.V.	Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas
WO2015110435A1 (en)	2014-01-21	2015-07-30	Janssen Pharmaceutica Nv	Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
US9895324B2 (en)	2014-03-26	2018-02-20	University Of Kentucky Research Foundation	Halogenated diarylacetylenes and methods of treating cancer
EP3134089A2 (en)	2014-04-23	2017-03-01	F. Hoffmann-La Roche AG	Mglu2/3 antagonists for the treatment of intellectual disabilities
CA2950952C (en)	2014-06-10	2023-01-10	Sanford-Burnham Medical Research Institute	Metabotropic glutamate receptor negative allosteric modulators (nams) and uses thereof
CN106243050B (zh) *	2016-08-10	2019-09-06	安徽恒星制药有限公司	一种适合工业化生产氯巴占的方法
CN109836356B (zh) *	2017-11-24	2022-03-08	沈阳化工研究院有限公司	一种芳甲醚衍生物及其应用
RU2702358C1 (ru) *	2019-06-04	2019-10-08	Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук	Способ получения 2,2,4-триалкил-2,3-дигидро-1Н-1,5-бензодиазепинов
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2000
- 2000-09-29 SI SI200030210T patent/SI1224174T1/xx unknown
- 2000-09-29 WO PCT/EP2000/009553 patent/WO2001029011A2/en active IP Right Grant
- 2000-09-29 RU RU2002110104/04A patent/RU2259360C2/ru not_active IP Right Cessation
- 2000-09-29 CA CA002386974A patent/CA2386974C/en not_active Expired - Fee Related
- 2000-09-29 ES ES00969347T patent/ES2204704T3/es not_active Expired - Lifetime
- 2000-09-29 PL PL00357418A patent/PL357418A1/xx unknown
- 2000-09-29 JP JP2001531811A patent/JP3857138B2/ja not_active Expired - Fee Related
- 2000-09-29 DE DE60005386T patent/DE60005386T2/de not_active Expired - Lifetime
- 2000-09-29 PT PT00969347T patent/PT1224174E/pt unknown
- 2000-09-29 KR KR10-2002-7004838A patent/KR100480320B1/ko not_active IP Right Cessation
- 2000-09-29 EP EP00969347A patent/EP1224174B1/en not_active Expired - Lifetime
- 2000-09-29 CZ CZ20021653A patent/CZ20021653A3/cs unknown
- 2000-09-29 AU AU79102/00A patent/AU774451B2/en not_active Ceased
- 2000-09-29 IL IL14881600A patent/IL148816A0/xx active IP Right Grant
- 2000-09-29 YU YU26202A patent/YU26202A/sh unknown
- 2000-09-29 BR BR0014859-8A patent/BR0014859A/pt not_active Application Discontinuation
- 2000-09-29 AT AT00969347T patent/ATE250039T1/de not_active IP Right Cessation
- 2000-09-29 TR TR2002/01023T patent/TR200201023T2/xx unknown
- 2000-09-29 CN CNB008142742A patent/CN1195522C/zh not_active Expired - Fee Related
- 2000-09-29 HU HU0203142A patent/HUP0203142A3/hu unknown
- 2000-09-29 NZ NZ517999A patent/NZ517999A/en unknown
- 2000-09-29 DK DK00969347T patent/DK1224174T3/da active
- 2000-10-10 PE PE2000001083A patent/PE20010681A1/es not_active Application Discontinuation
- 2000-10-10 JO JO2000169A patent/JO2262B1/en active
- 2000-10-11 GC GCP2000950 patent/GC0000263A/en active
- 2000-10-12 CO CO00077957A patent/CO5261604A1/es not_active Application Discontinuation
- 2000-10-13 MY MYPI20004817A patent/MY125540A/en unknown
- 2000-10-13 US US09/687,240 patent/US6407094B1/en not_active Expired - Fee Related
- 2000-10-13 AR ARP000105386A patent/AR026029A1/es unknown
- 2000-10-14 EG EG20001310A patent/EG24079A/xx active
2002
- 2002-03-21 IL IL148816A patent/IL148816A/en not_active IP Right Cessation
- 2002-03-27 HR HR20020259A patent/HRP20020259A2/xx not_active Application Discontinuation
- 2002-03-28 ZA ZA200202544A patent/ZA200202544B/xx unknown
- 2002-04-10 NO NO20021690A patent/NO327817B1/no not_active IP Right Cessation
- 2002-04-15 MA MA26601A patent/MA26831A1/fr unknown
2003
- 2003-04-17 HK HK03102802A patent/HK1051038A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1379765A (zh)	2002-11-13
AR026029A1 (es)	2002-12-26
DE60005386D1 (de)	2003-10-23
KR20020038954A (ko)	2002-05-24
MY125540A (en)	2006-08-30
IL148816A0 (en)	2002-09-12
WO2001029011A2 (en)	2001-04-26
SI1224174T1 (en)	2003-12-31
CN1195522C (zh)	2005-04-06
HUP0203142A3 (en)	2003-03-28
EP1224174B1 (en)	2003-09-17
US6407094B1 (en)	2002-06-18
NO327817B1 (no)	2009-09-28
MA26831A1 (fr)	2004-12-20
JP3857138B2 (ja)	2006-12-13
PT1224174E (pt)	2004-01-30
YU26202A (sh)	2004-12-31
BR0014859A (pt)	2002-07-16
PL357418A1 (en)	2004-07-26
TR200201023T2 (tr)	2002-09-23
NO20021690L (no)	2002-04-10
NO20021690D0 (no)	2002-04-10
CA2386974C (en)	2009-10-13
CA2386974A1 (en)	2001-04-26
AU774451B2 (en)	2004-06-24
NZ517999A (en)	2004-07-30
CZ20021653A3 (cs)	2002-08-14
KR100480320B1 (ko)	2005-04-07
AU7910200A (en)	2001-04-30
IL148816A (en)	2006-10-31
CO5261604A1 (es)	2003-03-31
JO2262B1 (en)	2004-10-07
ATE250039T1 (de)	2003-10-15
JP2003512359A (ja)	2003-04-02
RU2259360C2 (ru)	2005-08-27
EG24079A (en)	2008-05-11
DK1224174T3 (da)	2004-01-26
DE60005386T2 (de)	2004-06-24
EP1224174A2 (en)	2002-07-24
PE20010681A1 (es)	2001-06-28
HK1051038A1 (en)	2003-07-18
GC0000263A (en)	2006-11-01
HUP0203142A2 (hu)	2003-02-28
WO2001029011A3 (en)	2001-11-08
ZA200202544B (en)	2003-09-23
ES2204704T3 (es)	2004-05-01

Legal Events

Date	Code	Title
2004-04-30	A1OB	Publication of a patent application
2004-10-19	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2008-12-09	OBST	Application withdrawn

Publication	Publication Date	Title
GC0000207A (en)	2006-03-29	Benzodiazepine derivatives
GC0000263A (en)	2006-11-01	Benzodiazepine derivatives
EG23817A (en)	2007-09-19	4-Phenyl-pyridine derivatives
HUP0201535A2 (en)	2002-08-28	5-cyano-2-aminopyrimidine derivatives
IL148167A0 (en)	2002-09-12	Amino-triazolopyridine derivatives
GC0000183A (en)	2006-03-29	3-Phenyl-pyridine derivatives
IL145739A0 (en)	2002-07-25	13-methyl-erythromycin derivatives
GC0000338A (en)	2007-03-31	5-Phenyl-pyrimidine derivatives
IL148837A0 (en)	2002-09-12	Isoxazolecarboxamide derivatives
GC0000191A (en)	2006-03-29	4-Phenyl-pyrimidine derivatives
IL155035A0 (en)	2003-10-31	Benzodiazepine derivatives
GB9925880D0 (en)	1999-12-29	B-Carboline derivatives
IL150132A0 (en)	2002-12-01	Cyclopenteneone derivatives
IL147636A0 (en)	2002-08-14	3-amino-2-benzyl-1-phenyl-propane derivatives
GC0000256A (en)	2006-11-01	Ethanesulfonyl-piperidine derivatives
IL145949A0 (en)	2002-07-25	1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives
PL351407A1 (en)	2003-04-22	Thio-oxindole derivatives
GB9907134D0 (en)	1999-05-19	Antimor napthylcombretastatin derivatives
IL146282A0 (en)	2002-07-25	Thio-oxindole derivatives
HK1043987A1 (zh)	2002-10-04	硫-羥吲衍生物